DE69738349D1 - Anthranilsäure diamide derivate, ihre herstellung und pharmazeutische verwendung als antigastrin mittel - Google Patents

Anthranilsäure diamide derivate, ihre herstellung und pharmazeutische verwendung als antigastrin mittel

Info

Publication number
DE69738349D1
DE69738349D1 DE69738349T DE69738349T DE69738349D1 DE 69738349 D1 DE69738349 D1 DE 69738349D1 DE 69738349 T DE69738349 T DE 69738349T DE 69738349 T DE69738349 T DE 69738349T DE 69738349 D1 DE69738349 D1 DE 69738349D1
Authority
DE
Germany
Prior art keywords
pct
anthranilic acid
antigastrine
agents
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69738349T
Other languages
English (en)
Other versions
DE69738349T2 (de
Inventor
Francesco Makovec
Walter Peris
Lucio Claudio Rovati
Luigi Angelo Rovati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rottapharm SpA
Original Assignee
Rottapharm SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rottapharm SpA filed Critical Rottapharm SpA
Application granted granted Critical
Publication of DE69738349D1 publication Critical patent/DE69738349D1/de
Publication of DE69738349T2 publication Critical patent/DE69738349T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DE69738349T 1996-07-02 1997-06-26 Anthranilsäurediamid-derivate, ihre herstellung und pharmazeutische verwendung als antigastrinmittel Expired - Lifetime DE69738349T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITTO960564 1996-07-02
IT96TO000564A IT1286141B1 (it) 1996-07-02 1996-07-02 Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico.
PCT/EP1997/003361 WO1998000404A1 (en) 1996-07-02 1997-06-26 Anthranilic acid diamides derivatives, their preparation and pharmaceutical use as anti-gastrin agents

Publications (2)

Publication Number Publication Date
DE69738349D1 true DE69738349D1 (de) 2008-01-17
DE69738349T2 DE69738349T2 (de) 2008-11-13

Family

ID=11414751

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738349T Expired - Lifetime DE69738349T2 (de) 1996-07-02 1997-06-26 Anthranilsäurediamid-derivate, ihre herstellung und pharmazeutische verwendung als antigastrinmittel

Country Status (13)

Country Link
US (1) US6075033A (de)
EP (1) EP0918754B1 (de)
JP (1) JP2000515497A (de)
AT (1) ATE380178T1 (de)
AU (1) AU724814B2 (de)
CA (1) CA2259345C (de)
DE (1) DE69738349T2 (de)
DK (1) DK0918754T3 (de)
ES (1) ES2299184T3 (de)
IT (1) IT1286141B1 (de)
PT (1) PT918754E (de)
WO (1) WO1998000404A1 (de)
ZA (1) ZA975898B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19935219A1 (de) 1999-07-27 2001-02-01 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
CA2445477A1 (en) * 2001-05-11 2002-11-21 Yamanouchi Pharmaceutical Co., Ltd. Antitumor agents
JP5197361B2 (ja) * 2005-06-06 2013-05-15 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ 睡眠障害を処置するための組成物および方法
EP2275421A1 (de) 2009-07-15 2011-01-19 Rottapharm S.p.A. Spiro-Amino-Verbindungen geeignet zur Behandlung von unter anderem Schlafstörungen und Drogenabhängigkeit

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1241029B (it) * 1990-12-11 1993-12-27 Rotta Research Lab Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione
IT1263116B (it) * 1992-04-09 1996-07-30 Rotta Research Lab Derivati basici dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso farmaceutico
IT1264765B1 (it) * 1993-03-10 1996-10-04 Rotta Research Lab Derivati dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso come farmaci potenzianti la
IT1261255B (it) * 1993-09-09 1996-05-09 Rotta Research Lab Derivati acidi poliamidici ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico.
IT1276462B1 (it) * 1995-07-03 1997-10-31 Rotta Research Lab Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico

Also Published As

Publication number Publication date
ATE380178T1 (de) 2007-12-15
ES2299184T3 (es) 2008-05-16
EP0918754A1 (de) 1999-06-02
EP0918754B1 (de) 2007-12-05
JP2000515497A (ja) 2000-11-21
AU724814B2 (en) 2000-09-28
AU3344897A (en) 1998-01-21
ITTO960564A1 (it) 1998-01-02
PT918754E (pt) 2008-03-04
DE69738349T2 (de) 2008-11-13
US6075033A (en) 2000-06-13
IT1286141B1 (it) 1998-07-07
ITTO960564A0 (de) 1996-07-02
DK0918754T3 (da) 2008-03-31
CA2259345C (en) 2006-01-31
CA2259345A1 (en) 1998-01-08
ZA975898B (en) 1998-01-30
WO1998000404A1 (en) 1998-01-08

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