DK97784A - Dna-segment - Google Patents

Dna-segment Download PDF

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Publication number
DK97784A
DK97784A DK97784A DK97784A DK97784A DK 97784 A DK97784 A DK 97784A DK 97784 A DK97784 A DK 97784A DK 97784 A DK97784 A DK 97784A DK 97784 A DK97784 A DK 97784A
Authority
DK
Denmark
Prior art keywords
gene
segment
dna
vector
yeast
Prior art date
Application number
DK97784A
Other languages
Danish (da)
English (en)
Other versions
DK97784D0 (da
Inventor
David Botstein
Ronald Wayne Davis
Gerald Ralph Fink
Alison Taunton-Rigby
Robert Gentry Knowlton
Jen-I Mao
Donald Taylor Moir
Christopher Godfrey Goff
Original Assignee
Collaborative Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23869556&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK97784(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Collaborative Res Inc filed Critical Collaborative Res Inc
Publication of DK97784D0 publication Critical patent/DK97784D0/da
Publication of DK97784A publication Critical patent/DK97784A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces
    • Y10S435/942—Saccharomyces cerevisiae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Prostheses (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Road Signs Or Road Markings (AREA)
  • Vessels, Lead-In Wires, Accessory Apparatuses For Cathode-Ray Tubes (AREA)
  • Devices For Indicating Variable Information By Combining Individual Elements (AREA)
DK97784A 1983-02-28 1984-02-24 Dna-segment DK97784A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/470,911 US4661454A (en) 1983-02-28 1983-02-28 GAL1 yeast promoter linked to non galactokinase gene

Publications (2)

Publication Number Publication Date
DK97784D0 DK97784D0 (da) 1984-02-24
DK97784A true DK97784A (da) 1984-08-29

Family

ID=23869556

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97784A DK97784A (da) 1983-02-28 1984-02-24 Dna-segment

Country Status (8)

Country Link
US (1) US4661454A (fr)
EP (1) EP0123811B1 (fr)
JP (1) JPS6058077A (fr)
AT (1) ATE64416T1 (fr)
CA (1) CA1283373C (fr)
DE (1) DE3484689D1 (fr)
DK (1) DK97784A (fr)
GB (1) GB2137208B (fr)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0128743A3 (fr) * 1983-06-07 1985-12-27 Genex Corporation Expression de gènes étrangers dans la levure
EP0132309A3 (fr) * 1983-06-27 1985-12-27 The Board Of Trustees Of The Leland Stanford Junior University Elément promoteur eucaryotique réglable
IL71555A (en) * 1984-04-15 1992-06-21 State Of Israel Israel Inst Fo Bovine interferon
ATE54167T1 (de) * 1984-12-06 1990-07-15 Fina Research Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.
US4861868A (en) * 1985-02-22 1989-08-29 Monsanto Company Production of proteins in procaryotes
US5037806A (en) * 1985-02-22 1991-08-06 Monsanto Company Biologically active method using somatotropins
EP0225887B1 (fr) * 1985-04-08 1994-06-08 Amgen Inc. Procede et activeur hybride permettant de commander la transcription de genes exogenes
JP2677350B2 (ja) * 1985-08-02 1997-11-17 メルク エンド カムパニ− インコ−ポレ−テツド 発現蛋白の発酵収率増大
JPH0668B2 (ja) * 1985-08-30 1994-01-05 財団法人化学及血清療法研究所 単純ヘルペスウイルス遺伝子が組込まれた組換えプラスミド
US5002876A (en) * 1986-09-22 1991-03-26 Phillips Petroleum Company Yeast production of human tumor necrosis factor
US5013652A (en) * 1986-10-14 1991-05-07 Genex Corporation Composite yeast vectors
US5882884A (en) * 1987-06-19 1999-03-16 Lucky Biotech Corporation Expression of proteinaceous sweeteners in yeast
US5487990A (en) * 1988-07-01 1996-01-30 The General Hospital Corporation Glucose-regulated promoter of yeast acetyl-CoA hydrolase
US5057419A (en) * 1988-09-22 1991-10-15 Rutgers University Genetically engineered plasmid and organisms for the production of specialized oils
US5187079A (en) * 1988-12-21 1993-02-16 The Research Foundation Of State University Of New York Glucose-repressible gene for the regulated expression of proteins and expression vector therefor
WO1991014780A1 (fr) * 1990-03-21 1991-10-03 Board Of Regents, The University Of Texas System Vecteurs d'expression de levure
WO1992005244A1 (fr) 1990-09-13 1992-04-02 Duke University Expression de recepteurs couples a une proteine g dans une cellule de levure
JPH04287683A (ja) * 1991-03-14 1992-10-13 Ajinomoto Co Inc 酵母変異株およびそれを利用するペプチドまたは蛋白質　　　　　　　　　　　等の製造方法
GB9226065D0 (en) * 1992-12-14 1993-02-10 Ici Plc Peptides
DE4303744A1 (de) * 1993-02-09 1994-08-11 Univ Autonoma De Nuevo Leon Mo Hundewachstumshormon
DE19534120A1 (de) 1995-09-14 1997-03-20 Hoechst Ag Verwendung von Cytohesin-PH-Peptiden zur Beeinflußung der Adhäsionsfähigkeit von Integrinen
AU1206397A (en) 1995-12-29 1997-07-28 Guilford Pharmaceuticals Inc. Method and kit for detection of multiple protein interactions
US5886151A (en) 1996-05-03 1999-03-23 Regents Of The University Of Minnesota Candida albicans integrin-like protein
IL129379A (en) 1996-10-16 2008-12-29 Zymogenetics Inc Fibroblast growth factor homologues
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
GB9726897D0 (en) * 1997-12-20 1998-02-18 Zeneca Ltd Process
DE69941126D1 (de) 1998-09-23 2009-08-27 Zymogenetics Inc Cytokinerezeptor zalpha11
ATE404668T1 (de) 1998-12-07 2008-08-15 Zymogenetics Inc Wachstumsfaktor-homologe zvegf-3
ES2329254T3 (es) 1999-01-07 2009-11-24 Zymogenetics, Inc. Usos terapeuticos de receptores solubles de br43x2.
US7833529B1 (en) 1999-01-07 2010-11-16 Zymogenetics, Inc. Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
CN1927883B (zh) 1999-03-09 2011-09-21 津莫吉尼蒂克斯公司 新的细胞因子zalpha11配体
AU6069800A (en) 1999-07-07 2001-01-30 Zymogenetics Inc. Human cytokine receptor
AU2292601A (en) 1999-12-23 2001-07-03 Zymogenetics Inc. Novel cytokine zcyto18
ATE473280T1 (de) 2000-05-11 2010-07-15 Zymogenetics Inc Zsig33-ähnliche peptide
PT1325115T (pt) 2000-06-26 2016-09-28 Zymogenetics Inc Recetor de citocina zcytor17
WO2002002627A2 (fr) 2000-06-30 2002-01-10 Zymogenetics, Inc. Proteine zcyto21de type interferon
EP1736545A3 (fr) 2000-08-08 2007-03-28 ZymoGenetics, Inc. Récepteurs de cytokines zcytor 11 solubles
EP1354956A4 (fr) * 2000-12-28 2004-10-27 Toyota Motor Co Ltd Procede de production d'alcool de prenyl
JP2004533997A (ja) 2001-02-20 2004-11-11 ザイモジェネティクス，インコーポレイティド Ｂｃｍａ及びｔａｃｉの両者を結合する抗体
DK2116259T3 (da) 2001-05-24 2012-05-21 Zymogenetics Inc TACI-immunoglobulinfusionsproteiner
EP2130919A1 (fr) 2001-11-05 2009-12-09 ZymoGenetics, Inc. Antagonistes IL-21
PT1576112E (pt) 2002-01-18 2012-05-25 Zymogenetics Inc Multímeros de receptor de citocina zcytor17
CN100575482C (zh) 2002-01-18 2009-12-30 津莫吉尼蒂克斯公司 新的细胞因子zcytor17配体
EP1497415B1 (fr) 2002-04-19 2010-12-29 ZymoGenetics, L.L.C. Methodes d'identification ou modulation de l'interaction d'un recepteur de cytokine et son ligand
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
US7785871B2 (en) * 2002-10-09 2010-08-31 Intrexon Corporation DNA cloning vector plasmids and methods for their use
US20080050808A1 (en) * 2002-10-09 2008-02-28 Reed Thomas D DNA modular cloning vector plasmids and methods for their use
US7157559B2 (en) 2003-08-07 2007-01-02 Zymogenetics, Inc. Homogeneous preparations of IL-28 and IL-29
CN1283792C (zh) * 2003-11-14 2006-11-08 余伟明 生物大分子组分相分离法
CA2558811A1 (fr) 2004-03-08 2005-09-22 Zymogenetics, Inc. Proteines de fusion dimeres et materiaux et methodes de production de ces proteines
CN1981047B (zh) * 2004-05-18 2013-08-21 英特拉克森公司 Dna克隆载体质粒的动态载体装配方法
EP2389944A1 (fr) 2004-07-29 2011-11-30 ZymoGenetics, L.L.C. Utilisation d'IL-28 et IL-29 pour traiter le cancer
EP1781784A2 (fr) 2004-08-02 2007-05-09 BASF Plant Science GmbH Procede pour l'isolement de sequences de terminaison de transcription
WO2006086396A2 (fr) 2005-02-08 2006-08-17 Zymogenetics, Inc. Anticorps et partenaires de liaison anti-il-20, anti-il-22 et anti-il-22ra, et methodes d'utilisation de ces anticorps et partenaires de liaison dans des processus inflammatoires
EP1891107B1 (fr) 2005-05-12 2011-07-06 ZymoGenetics, Inc. Compositions et procedes permettant de moduler des reponses immunitaires
JP5118037B2 (ja) 2005-08-09 2013-01-16 ザイモジェネティクス， インコーポレイテッド Ｔａｃｉ融合分子を用いた異常細胞増殖の処置及び予防のための方法
AR059945A1 (es) * 2005-08-09 2008-05-14 Zymogenetics Inc Metodos para tratar afecciones malignas de celulas b que utilizan una molecula de fusion taci-ig
US8153598B2 (en) * 2005-10-19 2012-04-10 Intrexon Corporation PKD ligands and polynucleotides encoding PKD ligands
UA98462C2 (ru) * 2006-05-15 2012-05-25 Арес Трейдинг С.А. Способы лечения аутоиммунных заболеваний с использованием слитой молекулы taci-ig
EP2164863A4 (fr) 2007-06-15 2010-07-28 Univ Arkansas Procédés de distribution de molécule à des cellules en utilisant une sous-unité de ricine et compositions associées
CA2697193C (fr) 2007-09-14 2017-06-06 Adimab, Inc. Bibliotheques d'anticorps synthetiques rationnelles et leurs utilisations
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
DK2225267T3 (en) 2007-11-21 2015-04-27 Roskilde Uni Polypeptides comprising a isbindende activity
WO2009080054A1 (fr) * 2007-12-21 2009-07-02 Ifxa A/S Inhibiteur de protéases
CN102037007A (zh) * 2008-01-25 2011-04-27 奥尔胡斯大学 选择性外部位点抑制papp-a对igfbp-4的活性
PL2274008T3 (pl) 2008-03-27 2014-07-31 Zymogenetics Inc Kompozycje i sposoby hamowania PDGFRbeta i VEGF-A
EP2623112B1 (fr) 2008-06-27 2015-03-04 Zymogenetics, Inc. Récepteurs de Fc gamma hybrides solubles et procédés associés
BR112012031329A2 (pt) 2010-06-09 2016-10-11 Zymogenetics Inc proteínas de fusão diméricas vstm3 e composições e métodos relacionados
CA3156904A1 (en) 2012-02-01 2013-08-08 Synthetic Genomics, Inc. Materials and methods for the synthesis of error-minimized nucleic acid molecules
WO2014202089A2 (fr) 2013-06-18 2014-12-24 Roskilde Universitet Variants de polypeptides antigel
CN106318943B (zh) * 2015-06-29 2019-03-05 中国科学院大连化学物理研究所 半乳糖激酶启动子和终止子及其应用
CN106318942B (zh) * 2015-06-29 2018-12-25 中国科学院大连化学物理研究所 一种半乳糖激酶启动子和终止子及其应用
JP6953020B2 (ja) 2015-09-08 2021-10-27 セリピオン， インコーポレイテッド ＡｐｏＡ−１融合ポリペプチドならびに関連する組成物および方法
WO2018136163A2 (fr) 2016-12-09 2018-07-26 Theripion, Inc. Polypeptides de fusion apoa-1 en tandem
NZ761636A (en) 2017-07-20 2023-07-28 Aptevo Res & Development Llc Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
RU2756100C1 (ru) 2017-12-20 2021-09-28 Харбор Байомед (Шанхай) Ко., Лтд Антитела, связывающие ctla-4, и их применение
US10150801B1 (en) 2017-12-27 2018-12-11 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
EP3732190A1 (fr) 2017-12-27 2020-11-04 Imunami Laboratories Pte. Ltd. Polypeptides recombinants et leurs procédés d'utilisation
EP4021512A1 (fr) 2019-08-26 2022-07-06 Imunami Laboratories Pte. Ltd. Polypeptides recombinants et leurs méthodes d'utilisation
US10675332B1 (en) 2019-08-26 2020-06-09 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
WO2021262081A1 (fr) 2020-06-22 2021-12-30 Imunami Laboratories Pte. Ltd. Polypeptides recombinants et combinaisons pour utilisation dans le traitement du cancer
CA3207134A1 (fr) 2021-02-19 2022-08-25 Jeffrey A. Ledbetter Polypeptides de fusion dnase, compositions et methodes associees

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
US4666847A (en) * 1981-01-16 1987-05-19 Collaborative Research, Inc. Recombinant DNA means and method
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
EP0128743A3 (fr) * 1983-06-07 1985-12-27 Genex Corporation Expression de gènes étrangers dans la levure
EP0132309A3 (fr) * 1983-06-27 1985-12-27 The Board Of Trustees Of The Leland Stanford Junior University Elément promoteur eucaryotique réglable

Also Published As

Publication number Publication date
GB2137208B (en) 1987-05-13
DE3484689D1 (de) 1991-07-18
ATE64416T1 (de) 1991-06-15
EP0123811A2 (fr) 1984-11-07
GB2137208A (en) 1984-10-03
DK97784D0 (da) 1984-02-24
GB8405129D0 (en) 1984-04-04
CA1283373C (fr) 1991-04-23
EP0123811A3 (en) 1986-03-26
US4661454A (en) 1987-04-28
EP0123811B1 (fr) 1991-06-12
JPS6058077A (ja) 1985-04-04

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