DK4269578T3 - Opløselig hyaluronidasesammensætning - Google Patents

Opløselig hyaluronidasesammensætning Download PDF

Info

Publication number
DK4269578T3
DK4269578T3 DK23191930.9T DK23191930T DK4269578T3 DK 4269578 T3 DK4269578 T3 DK 4269578T3 DK 23191930 T DK23191930 T DK 23191930T DK 4269578 T3 DK4269578 T3 DK 4269578T3
Authority
DK
Denmark
Prior art keywords
soluble hyaluronidase
hyaluronidase composition
composition
soluble
hyaluronidase
Prior art date
Application number
DK23191930.9T
Other languages
English (en)
Inventor
David Baker
Louis Bookbinder
Original Assignee
Halozyme Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40732065&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK4269578(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Halozyme Inc filed Critical Halozyme Inc
Application granted granted Critical
Publication of DK4269578T3 publication Critical patent/DK4269578T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2474—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01036—Hyaluronoglucuronidase (3.2.1.36)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK23191930.9T 2008-03-06 2009-03-06 Opløselig hyaluronidasesammensætning DK4269578T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6862208P 2008-03-06 2008-03-06
EP21189086.8A EP3960854B1 (en) 2008-03-06 2009-03-06 Large-scale production of soluble hyaluronidase

Publications (1)

Publication Number Publication Date
DK4269578T3 true DK4269578T3 (da) 2024-06-17

Family

ID=40732065

Family Applications (1)

Application Number Title Priority Date Filing Date
DK23191930.9T DK4269578T3 (da) 2008-03-06 2009-03-06 Opløselig hyaluronidasesammensætning

Country Status (17)

Country Link
US (2) US8187855B2 (da)
EP (6) EP4421168A2 (da)
JP (2) JP5650546B2 (da)
KR (2) KR20140130512A (da)
CN (2) CN106906196A (da)
CA (1) CA2717383C (da)
DK (1) DK4269578T3 (da)
ES (2) ES2887219T3 (da)
FI (1) FI4269578T3 (da)
HR (1) HRP20240797T3 (da)
IL (2) IL207398A (da)
LT (1) LT4269578T (da)
PL (1) PL4269578T3 (da)
PT (1) PT4269578T (da)
RS (1) RS65606B1 (da)
SI (1) SI4269578T1 (da)
WO (1) WO2009111066A1 (da)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2218779A1 (en) 2002-12-16 2010-08-18 Halozyme, Inc. Human chondroitinase glycoprotein (chasegp), process for preparing the same, and pharmaceutical compositions comprising thereof
US20060104968A1 (en) * 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US7871607B2 (en) 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
ES2335005T5 (es) * 2003-03-05 2013-04-17 Halozyme, Inc. Glicoproteína hialuronidasa soluble (shasegp), proceso para prepararla, usos y composiciones farmacéuticas que la comprenden
JP4636847B2 (ja) 2004-10-13 2011-02-23 株式会社ロッテ 全粒粉からなる小麦粉の加工方法及びその加工方法により得られた加工小麦粉並びにその加工小麦粉を使用した食品
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
PL4269578T3 (pl) 2008-03-06 2024-07-29 Halozyme, Inc. Kompozycja rozpuszczalnej hialuronidazy
TWI489994B (zh) * 2008-03-17 2015-07-01 Baxter Healthcare Sa 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法
CA2721229C (en) 2008-04-14 2022-08-23 Halozyme, Inc. Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
TWI394580B (zh) * 2008-04-28 2013-05-01 Halozyme Inc 超快起作用胰島素組成物
EA022752B1 (ru) 2008-12-09 2016-02-29 Галозим, Инк. Длинные растворимые полипептиды рн20 и их использование
ES2385251B1 (es) * 2009-05-06 2013-05-06 Fundació Privada Institut D'investigació Biomèdica De Bellvitge Adenovirus oncolíticos para el tratamiento del cáncer.
JP5734985B2 (ja) * 2009-09-17 2015-06-17 バクスター・ヘルスケヤー・ソシエテ・アノニムＢａｘｔｅｒ Ｈｅａｌｔｈｃａｒｅ ＳＡ ヒアルロニダーゼおよび免疫グロブリンの安定な共製剤およびそれらの使用方法
DK2595624T3 (da) 2010-07-20 2018-03-26 Halozyme Inc Fremgangsmåder til behandling eller forebyggelse af negative bivirkninger forbundet med administration af et anti-hyaluronanmiddel
US8740982B2 (en) 2010-10-26 2014-06-03 Kyphon Sarl Devices containing a chemonucleolysis agent and methods for treating an intervertebral disc or spinal arachnoiditis
US9414930B2 (en) 2010-10-26 2016-08-16 Kyphon SÀRL Activatable devices containing a chemonucleolysis agent
US8404268B2 (en) 2010-10-26 2013-03-26 Kyphon Sarl Locally targeted anti-fibrotic agents and methods of use
JP2014510045A (ja) 2011-02-08 2014-04-24 ハロザイム インコーポレイテッド ヒアルロナン分解酵素の組成物および脂質製剤ならびに良性前立腺肥大症の治療のためのその使用
KR101654810B1 (ko) * 2011-04-05 2016-09-07 바이오스트림테크놀러지스(주) 신규미생물 비브리오 스플린디더스 ｂｓｔ３９８ 및 이를 이용한 저분자 히알루론산의 제조방법
US20120258519A1 (en) * 2011-04-10 2012-10-11 Therapeutic Proteins Inc. Protein Harvesting
NZ618331A (en) 2011-06-17 2016-04-29 Halozyme Inc Stable formulations of a hyaluronan-degrading enzyme
US9993529B2 (en) 2011-06-17 2018-06-12 Halozyme, Inc. Stable formulations of a hyaluronan-degrading enzyme
WO2013040501A1 (en) 2011-09-16 2013-03-21 Pharmathene, Inc. Compositions and combinations of organophosphorus bioscavengers and hyaluronan-degrading enzymes, and uses thereof
EP2771028A2 (en) 2011-10-24 2014-09-03 Halozyme, Inc. Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
EP2771038B1 (en) * 2011-10-26 2018-10-10 Amgen Inc. Methods of reducing or eliminating protein modification and degradation arising from exposure to uv light
DK3130347T3 (da) * 2011-12-30 2019-10-14 Halozyme Inc PH20-polypeptidvarianter, formuleringer og anvendelser deraf
AU2013243873B2 (en) 2012-04-04 2016-08-25 Halozyme, Inc. Combination therapy with an anti - hyaluronan agent and a tumor - targeted taxane
WO2014062856A1 (en) 2012-10-16 2014-04-24 Halozyme, Inc. Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
KR101454646B1 (ko) * 2012-11-05 2014-10-27 (주)한국비엠아이 히알루로니다아제의 안정화 제제 및 이를 포함하는 액상제제
AR093460A1 (es) 2012-11-14 2015-06-10 Merck Patent Ges Mit Beschränkter Haftung Medios de cultivo celular
CN103173474B (zh) * 2013-03-27 2014-08-27 广州白云山拜迪生物医药有限公司 一种用于cho细胞表达可溶性重组人透明质酸酶ph20的基因序列
KR101387097B1 (ko) 2013-04-02 2014-04-29 유한회사 마스터이미지쓰리디아시아 삼중 광분할 방법과 이를 이용한 입체 영상장치
ITMI20130992A1 (it) * 2013-06-17 2014-12-18 Fidia Farmaceutici Ialuronidasi batterica e metodo per la sua produzione
TW201534726A (zh) 2013-07-03 2015-09-16 Halozyme Inc 熱穩定ｐｈ２０玻尿酸酶變異體及其用途
US20160257754A1 (en) 2013-10-16 2016-09-08 Momenta Pharmaceuticals Inc. Sialylated glycoproteins
US9603927B2 (en) 2014-02-28 2017-03-28 Janssen Biotech, Inc. Combination therapies with anti-CD38 antibodies
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
HUE043847T2 (hu) 2014-08-28 2019-09-30 Halozyme Inc Hialuronán-lebontó enzimmel és egy immun checkpoint inhibitorral végzett kombinációs terápia
DK3207130T3 (da) 2014-10-14 2019-11-11 Halozyme Inc Sammensætninger af Adenosin Deaminase-2 (ADA2), varianter deraf og fremgangsmåder til anvendelse af samme
WO2016085545A1 (en) * 2014-11-26 2016-06-02 River Road Research, Inc. Method for converting food waste and other biological waste into invertebrate feed
KR101702024B1 (ko) 2015-04-06 2017-02-02 유한회사 마스터이미지쓰리디아시아 원격정렬형 입체영상장치 및 이를 이용한 입체영상상영방법
US9981021B1 (en) 2015-04-09 2018-05-29 Kinetiq, Inc. Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof
BR112017024877A2 (pt) 2015-05-20 2019-09-17 Janssen Biotech, Inc. anticorpo anti-cd38 e seu uso no tratamento de amiloidose de cadeia leve e outras malignidades hematológicas positivas para cd38
MA43187B1 (fr) 2015-11-03 2021-02-26 Janssen Biotech Inc Formulations sous-cutanée d'anticorps anti-cd38 et leurs utilisations
EP3973973A1 (en) 2017-10-31 2022-03-30 KaliVir Immunotherapeutics, Inc. Platform oncolytic vector for systemic delivery
US11618787B2 (en) 2017-10-31 2023-04-04 Janssen Biotech, Inc. Methods of treating high risk multiple myeloma
CN107805277A (zh) * 2018-01-29 2018-03-16 浙江海洋大学 曼氏无针乌贼精子表面蛋白及制备方法和用途
WO2019222435A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20
WO2021165226A1 (en) 2020-02-17 2021-08-26 Biotest Ag Subcutaneous administration of factor viii
CN111733148A (zh) * 2020-06-15 2020-10-02 南通大学 一种重组spam1蛋白及其应用
AU2021320569A1 (en) * 2020-08-07 2022-10-27 Alteogen, Inc Method for producing recombinant hyaluronidase
BR112023022681A2 (pt) 2021-04-30 2024-01-23 Kalivir Immunotherapeutics Inc Vírus oncolíticos para expressão modificada de mhc
EP4380618A2 (en) 2021-08-02 2024-06-12 argenx BV Subcutaneous unit dosage forms
PE20241337A1 (es) 2021-09-14 2024-07-03 Takeda Pharmaceuticals Co Administracion facilitada de formulaciones concentradas de anticuerpos mediante el uso de hialuronidasa
CN114634920B (zh) * 2022-03-24 2024-02-27 江南大学 一种产人源透明质酸酶ph20的重组毕赤酵母及其构建方法
CN117887691B (zh) * 2023-12-27 2024-07-12 山东福瑞达医药集团有限公司 一种透明质酸酶融合蛋白、酵母工程菌及构建方法与应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0263417A1 (de) 1986-09-30 1988-04-13 BIOCHEMIE Gesellschaft m.b.H. Verwendung von Hyaluronidase
ZA912770B (en) 1990-04-16 1992-01-29 Bethesda Eye Inst Enzymatic disinsertion of vitreous body
US5721348A (en) * 1990-12-14 1998-02-24 University Of Connecticut DNA encoding PH-20 proteins
US5705364A (en) * 1995-06-06 1998-01-06 Genentech, Inc. Mammalian cell culture process
US5958750A (en) * 1996-07-03 1999-09-28 Inctye Pharmaceuticals, Inc. Human hyaluronidase
US6193963B1 (en) * 1996-10-17 2001-02-27 The Regents Of The University Of California Method of treating tumor-bearing patients with human plasma hyaluronidase
US6528286B1 (en) * 1998-05-29 2003-03-04 Genentech, Inc. Mammalian cell culture process for producing glycoproteins
SK17612001A3 (sk) * 1999-06-12 2002-04-04 Merck Patent Gmbh Hyaluronidáza z Hirudinaria manillensis, jej izolácia, čistenie a rekombinantné spôsoby jej výroby
FR2809821B1 (fr) 2000-06-02 2002-09-20 Inst Francais Du Petrole Dispositif de connexion electrique etanche d'electrodes par cable blinde et systeme pour mesures petrophysiques utilisant le dispositif
US6571605B2 (en) 2001-01-19 2003-06-03 Larry Keith Johnson Constant-head soil permeameter for determining the hydraulic conductivity of earthen materials
US6745776B2 (en) 2001-04-10 2004-06-08 David B. Soll Methods for reducing postoperative intraocular pressure
US7153124B2 (en) 2002-08-09 2006-12-26 The Boeing Company Preforming thermoplastic ducts
US20090123367A1 (en) * 2003-03-05 2009-05-14 Delfmems Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
ES2335005T5 (es) * 2003-03-05 2013-04-17 Halozyme, Inc. Glicoproteína hialuronidasa soluble (shasegp), proceso para prepararla, usos y composiciones farmacéuticas que la comprenden
US20060104968A1 (en) 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US7871607B2 (en) * 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
JP4926448B2 (ja) * 2005-10-27 2012-05-09 三省製薬株式会社 老化防止剤
PL4269578T3 (pl) 2008-03-06 2024-07-29 Halozyme, Inc. Kompozycja rozpuszczalnej hialuronidazy
TWI489994B (zh) * 2008-03-17 2015-07-01 Baxter Healthcare Sa 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法
CA2721229C (en) * 2008-04-14 2022-08-23 Halozyme, Inc. Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
US20090311237A1 (en) * 2008-04-14 2009-12-17 Frost Gregory I Combination therapy using a soluble hyaluronidase and a bisphosphonate
TWI394580B (zh) * 2008-04-28 2013-05-01 Halozyme Inc 超快起作用胰島素組成物
EA022752B1 (ru) * 2008-12-09 2016-02-29 Галозим, Инк. Длинные растворимые полипептиды рн20 и их использование
JP5734985B2 (ja) 2009-09-17 2015-06-17 バクスター・ヘルスケヤー・ソシエテ・アノニムＢａｘｔｅｒ Ｈｅａｌｔｈｃａｒｅ ＳＡ ヒアルロニダーゼおよび免疫グロブリンの安定な共製剤およびそれらの使用方法
DK2595624T3 (da) 2010-07-20 2018-03-26 Halozyme Inc Fremgangsmåder til behandling eller forebyggelse af negative bivirkninger forbundet med administration af et anti-hyaluronanmiddel

Also Published As

Publication number Publication date
EP3760715B1 (en) 2021-08-04
JP5856261B2 (ja) 2016-02-09
RS65606B1 (sr) 2024-07-31
EP3760715A1 (en) 2021-01-06
US8343487B2 (en) 2013-01-01
IL207398A (en) 2014-04-30
KR20100135777A (ko) 2010-12-27
LT4269578T (lt) 2024-09-10
US8187855B2 (en) 2012-05-29
PT4269578T (pt) 2024-06-18
EP2674487A2 (en) 2013-12-18
FI4269578T3 (fi) 2024-06-07
CN106906196A (zh) 2017-06-30
EP3960854B1 (en) 2024-07-17
HRP20240797T3 (hr) 2024-09-13
US20120196348A1 (en) 2012-08-02
IL207398A0 (en) 2010-12-30
EP2268805B1 (en) 2015-05-06
EP4269578B1 (en) 2024-06-05
PL4269578T3 (pl) 2024-07-29
KR20140130512A (ko) 2014-11-10
EP4421168A2 (en) 2024-08-28
IL223420A (en) 2014-04-30
EP2268805A1 (en) 2011-01-05
EP3960854A1 (en) 2022-03-02
JP2015006199A (ja) 2015-01-15
WO2009111066A1 (en) 2009-09-11
SI4269578T1 (sl) 2024-07-31
KR101489028B1 (ko) 2015-02-03
JP2011512844A (ja) 2011-04-28
IL223420A0 (en) 2013-02-03
CA2717383A1 (en) 2009-09-11
ES2887219T3 (es) 2021-12-22
EP4269578B8 (en) 2024-07-17
CA2717383C (en) 2017-01-03
CN101970650B (zh) 2017-07-25
ES2537340T3 (es) 2015-06-05
CN101970650A (zh) 2011-02-09
US20110053247A1 (en) 2011-03-03
EP4269578A1 (en) 2023-11-01
EP2674487A3 (en) 2014-02-26
JP5650546B2 (ja) 2015-01-07

Similar Documents

Publication Publication Date Title
DK4269578T3 (da) Opløselig hyaluronidasesammensætning
DK2634231T3 (da) Sammensætninger
BRPI0906749A2 (pt) Composição
BRPI0913808A2 (pt) composição
SMT201600307B (it) Composizione liposomiale
DE602008002756D1 (de) Bauzusammensetzung
BRPI0810634A2 (pt) Composições fungicidas
BRPI0917231A2 (pt) composição
IT1392101B1 (it) Composizione comprendente isoflavoni
BRPI1013588A2 (pt) composição
DK2308877T3 (da) Imidazopyridin-2-on-derivater
BRPI0813775A2 (pt) Composição
BRPI0914763A2 (pt) composição aglutinante
BRPI1015474A2 (pt) composição
ATE528048T1 (de) Schweisshemmende/desodorierende zusammensetzung
FIC20240018I1 (fi) Vamoroloni
BRPI0810557A2 (pt) composição
DK2275414T3 (da) Cyclopentylacrylamidderivat
BRPI0811274A2 (pt) Composição
DE112009005504A5 (de) Schmiermittelzusammensetzung
BRPI0908558A2 (pt) composição lubrificante
ATE534634T1 (de) 2-phenyl-4-cyclopropyl-pyrimidinderivate
BRPI0811002A2 (pt) Composição biofertilizante
BRPI1005290A2 (pt) composição
BRPI0820960A2 (pt) composição