SMT201600307B - Composizione liposomiale - Google Patents
Composizione liposomialeInfo
- Publication number
- SMT201600307B SMT201600307B SM201600307T SM201600307T SMT201600307B SM T201600307 B SMT201600307 B SM T201600307B SM 201600307 T SM201600307 T SM 201600307T SM 201600307 T SM201600307 T SM 201600307T SM T201600307 B SMT201600307 B SM T201600307B
- Authority
- SM
- San Marino
- Prior art keywords
- liposomial
- composition
- liposomial composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16465309P | 2009-03-30 | 2009-03-30 | |
| JP2009082521 | 2009-03-30 | ||
| PCT/JP2010/055770 WO2010113984A1 (ja) | 2009-03-30 | 2010-03-30 | リポソーム組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201600307B true SMT201600307B (it) | 2016-11-10 |
Family
ID=42828273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM201600307T SMT201600307B (it) | 2009-03-30 | 2016-09-08 | Composizione liposomiale |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US20120058178A1 (it) |
| EP (1) | EP2415470B1 (it) |
| JP (1) | JP5551683B2 (it) |
| KR (1) | KR101495951B1 (it) |
| CN (1) | CN102369008B (it) |
| AU (1) | AU2010232347A1 (it) |
| BR (1) | BRPI1014527B8 (it) |
| CA (1) | CA2756811C (it) |
| CO (1) | CO6430500A2 (it) |
| CY (1) | CY1118231T1 (it) |
| DK (1) | DK2415470T3 (it) |
| ES (1) | ES2593027T3 (it) |
| HK (1) | HK1165707A1 (it) |
| HR (1) | HRP20161157T1 (it) |
| HU (1) | HUE029577T2 (it) |
| IL (1) | IL215059A (it) |
| LT (1) | LT2415470T (it) |
| MA (1) | MA33127B1 (it) |
| ME (1) | ME02518B (it) |
| MX (1) | MX2011009632A (it) |
| MY (1) | MY160203A (it) |
| NZ (1) | NZ595212A (it) |
| PE (2) | PE20120923A1 (it) |
| PL (1) | PL2415470T3 (it) |
| PT (1) | PT2415470T (it) |
| RS (1) | RS55148B1 (it) |
| SG (1) | SG174255A1 (it) |
| SI (1) | SI2415470T1 (it) |
| SM (1) | SMT201600307B (it) |
| TW (1) | TWI392519B (it) |
| UA (1) | UA103794C2 (it) |
| WO (1) | WO2010113984A1 (it) |
| ZA (1) | ZA201106535B (it) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8097648B2 (en) | 1998-06-17 | 2012-01-17 | Eisai R&D Management Co., Ltd. | Methods and compositions for use in treating cancer |
| CN101209243B (zh) | 2006-12-29 | 2010-12-08 | 石药集团中奇制药技术（石家庄）有限公司 | 一种脂质体药物及其制备方法 |
| SI2415470T1 (sl) | 2009-03-30 | 2016-12-30 | Eisai R&D Management Co., Ltd. | Liposomski sestavek |
| US9968583B2 (en) | 2009-03-30 | 2018-05-15 | Eisai R & D Management Co., Ltd. | Method of manufacture of liposome composition |
| RU2561582C2 (ru) * | 2010-11-19 | 2015-08-27 | Российская Федерация в лице Министерства промышленности и торговли Российской Федерации | Инъекционная лекарственная форма олигопептидного препарата для лечения рассеянного склероза и способ ее получения |
| WO2012119077A1 (en) | 2011-03-02 | 2012-09-07 | Morphotek Inc. | Co -administration of eribulin and farletuzumab for the treatment of breast cancer |
| CA2899882C (en) * | 2013-02-01 | 2023-12-12 | Zoneone Pharma, Inc. | Remote loading of sparingly water-soluble drugs into liposomes |
| CN106999419A (zh) | 2014-08-04 | 2017-08-01 | 佐尼奥尼制药股份有限公司 | 远程装载略微水溶性药物至脂质膜泡 |
| JP2018507227A (ja) | 2015-03-03 | 2018-03-15 | キュアポート インコーポレイテッド | 二薬搭載リポソーム医薬製剤 |
| HRP20211776T8 (hr) | 2015-09-18 | 2022-03-18 | Technische Universität München | Ligandi za integrin alfavbeta6, njihova sinteza i upotreba |
| MA43184A (fr) * | 2015-11-02 | 2021-04-14 | Fujifilm Corp | Composition liposomale et son procédé de production |
| EP3449921B1 (en) | 2016-04-28 | 2023-05-31 | Eisai R&D Management Co., Ltd. | Eribulin for inhibiting tumor growth |
| RU2765736C2 (ru) | 2017-01-18 | 2022-02-02 | Темасек Лайф Сайенсиз Лаборатори Лимитед | Гиперстабилизированные липосомы, повышающие направленное таргетирование митотических клеток |
| WO2018167295A1 (en) | 2017-03-17 | 2018-09-20 | Technische Universität München | LIGANDS FOR INTEGRIN αvβ8, SYNTHESIS AND USES THEREOF |
| CN110505869A (zh) * | 2017-03-31 | 2019-11-26 | 富士胶片株式会社 | 脂质体组合物及医药组合物 |
| EP3713565A1 (en) | 2017-11-20 | 2020-09-30 | Basilea Pharmaceutica International AG | Pharmaceutical combinations for use in the treatment of neoplastic diseases |
| US11083705B2 (en) | 2019-07-26 | 2021-08-10 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| CN115666552A (zh) * | 2020-05-29 | 2023-01-31 | 江苏恒瑞医药股份有限公司 | 含有乙二胺四乙酸或其盐的艾日布林或其可药用盐脂质体 |
| CN115957351B (zh) * | 2022-11-15 | 2023-06-27 | 中国人民解放军海军第九七一医院 | 一种碘海醇注射液及其制备方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5736155A (en) * | 1984-08-08 | 1998-04-07 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
| IL91664A (en) | 1988-09-28 | 1993-05-13 | Yissum Res Dev Co | Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release |
| GB9126209D0 (en) | 1991-12-10 | 1992-02-12 | Orion Yhtymae Oy | Drug formulations for parenteral use |
| US5759573A (en) | 1993-04-22 | 1998-06-02 | Depotech Corporation | Cyclodextrin liposomes encapsulating pharmacologic compounds and methods for their use |
| FR2736056B1 (fr) | 1995-06-29 | 1997-08-08 | Commissariat Energie Atomique | Derives de cyclodextrines, leur preparation et leur utilisation pour incorporer des molecules hydrophobes dans des systemes de tensioactifs organises |
| US6051251A (en) | 1997-11-20 | 2000-04-18 | Alza Corporation | Liposome loading method using a boronic acid compound |
| US8097648B2 (en) | 1998-06-17 | 2012-01-17 | Eisai R&D Management Co., Ltd. | Methods and compositions for use in treating cancer |
| US6653341B1 (en) | 1998-06-17 | 2003-11-25 | Eisai Co., Ltd. | Methods and compositions for use in treating cancer |
| EP2277873B1 (en) | 1998-06-17 | 2012-05-30 | Eisai R&D Management Co., Ltd. | Intermediate compound for the preparation of halichondrin analogs |
| US6593308B2 (en) | 1999-12-03 | 2003-07-15 | The Regents Of The University Of California | Targeted drug delivery with a hyaluronan ligand |
| CN1116875C (zh) | 2000-10-19 | 2003-08-06 | 南京振中生物工程有限公司 | 紫杉醇脂质组合物及其制备方法 |
| PT1443900E (pt) * | 2001-11-13 | 2012-08-01 | Celator Pharmaceuticals Inc | Composições de veículo lipídico com estabilidade melhorada no sangue |
| WO2003041682A2 (en) | 2001-11-13 | 2003-05-22 | Celator Technologies, Inc. | Lipid carrier compositions and methods for improved drug retention |
| DE10255106A1 (de) | 2002-11-24 | 2004-06-09 | Novosom Ag | Liposomale Glucocorticoide |
| AU2003293140A1 (en) | 2002-11-26 | 2004-06-18 | Gilead Sciences, Inc. | Method of drug loading in liposomes by gradient |
| EP1435231B8 (en) * | 2002-12-31 | 2010-03-03 | Zydus BSV Pharma Private Limited | Non-pegylated long-circulating liposomes |
| JPWO2004089419A1 (ja) * | 2003-04-04 | 2006-07-06 | 国立大学法人 東京大学 | 抗ｍｔ−ｍｍｐモノクローナル抗体含有脂質膜構造体 |
| US6747011B1 (en) | 2003-06-04 | 2004-06-08 | A.P. Group, Inc. | Antitumor drugs and methods |
| US20050129753A1 (en) | 2003-11-14 | 2005-06-16 | Gabizon Alberto A. | Method for drug loading in liposomes |
| JPWO2005073223A1 (ja) | 2004-01-29 | 2007-09-13 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | マクロライド系化合物の安定化方法 |
| DK1746976T3 (en) * | 2004-05-03 | 2017-04-10 | Merrimack Pharmaceuticals Inc | LIPOSOMES SUITABLE FOR PHARMACEUTICAL SUPPLY |
| DE602005018043D1 (de) | 2004-05-17 | 2010-01-14 | Tekmira Pharmaceuticals Corp | Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung |
| EP3587408A1 (en) | 2004-06-03 | 2020-01-01 | Eisai R&D Management Co., Ltd. | Intermediates for the preparation of halichondrin b |
| CN101072588B (zh) | 2004-10-06 | 2012-11-28 | 不列颠哥伦比亚抗癌机构 | 用于治疗癌症的具有改善的药物保留的脂质体 |
| TWI373473B (en) | 2005-09-02 | 2012-10-01 | Otsuka Pharma Co Ltd | Anticancer agent |
| CN101209243B (zh) | 2006-12-29 | 2010-12-08 | 石药集团中奇制药技术（石家庄）有限公司 | 一种脂质体药物及其制备方法 |
| US20090196913A1 (en) | 2007-05-11 | 2009-08-06 | Ken Shi Kun Huang | Anti-Alpha-V Immunoliposome Composition, Methods, and Uses |
| US20090196917A1 (en) | 2008-02-01 | 2009-08-06 | University Of Kentucky Research Foundation | Liposomal Formulations of Hydrophobic Lactone Drugs in the Presence of Metal Ions |
| US9968583B2 (en) | 2009-03-30 | 2018-05-15 | Eisai R & D Management Co., Ltd. | Method of manufacture of liposome composition |
| SI2415470T1 (sl) | 2009-03-30 | 2016-12-30 | Eisai R&D Management Co., Ltd. | Liposomski sestavek |
| US8203010B2 (en) | 2010-01-26 | 2012-06-19 | Eisai R&D Management Co., Ltd. | Compounds useful in the synthesis of halichondrin B analogs |
| US20140248263A1 (en) | 2011-04-08 | 2014-09-04 | The University Of British Columbia | Bisphenol compounds and methods for their use |
| CA2842306A1 (en) | 2011-07-19 | 2013-01-24 | Stc.Unm | Intraperitoneally-administered nanocarriers that release their therapeutic load based on the inflammatory environment of cancers |
| KR102265952B1 (ko) | 2013-06-26 | 2021-06-16 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 암 치료 병용요법으로서 에리불린 및 렌바티닙의 용도 |
| WO2015042279A1 (en) | 2013-09-18 | 2015-03-26 | Stc. Unm | Torroidal mesoporous silica nanoparticles (tmsnps) and related protocells |
| WO2015095784A1 (en) | 2013-12-19 | 2015-06-25 | Luminus Biosciences, Inc. | Solid nanoparticle formulation of microtubule inhibitors with reduced ostwald ripening for oral administration |
| CA2940983A1 (en) | 2014-03-03 | 2015-09-11 | Eisai R&D Management Co., Ltd. | Use of eribulin and mtor inhibitors as combination therapy for the treatment of cancer |
| EP3148336B1 (en) | 2014-05-28 | 2019-10-02 | Eisai R&D Management Co., Ltd. | Eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer |
| CN105640935A (zh) | 2014-11-12 | 2016-06-08 | 天津市汉康医药生物技术有限公司 | 供注射用甲磺酸艾日布林药物组合物 |
-
2010
- 2010-03-30 SI SI201031275A patent/SI2415470T1/sl unknown
- 2010-03-30 TW TW099109838A patent/TWI392519B/zh active
- 2010-03-30 CN CN201080014698.2A patent/CN102369008B/zh active Active
- 2010-03-30 WO PCT/JP2010/055770 patent/WO2010113984A1/ja active Application Filing
- 2010-03-30 MX MX2011009632A patent/MX2011009632A/es active IP Right Grant
- 2010-03-30 SG SG2011063880A patent/SG174255A1/en unknown
- 2010-03-30 PL PL10758755.2T patent/PL2415470T3/pl unknown
- 2010-03-30 LT LTEP10758755.2T patent/LT2415470T/lt unknown
- 2010-03-30 BR BRPI1014527A patent/BRPI1014527B8/pt active IP Right Grant
- 2010-03-30 RS RS20160763A patent/RS55148B1/sr unknown
- 2010-03-30 UA UAA201111426A patent/UA103794C2/ru unknown
- 2010-03-30 KR KR1020117022860A patent/KR101495951B1/ko active IP Right Grant
- 2010-03-30 JP JP2011507240A patent/JP5551683B2/ja active Active
- 2010-03-30 EP EP10758755.2A patent/EP2415470B1/en active Active
- 2010-03-30 PT PT107587552T patent/PT2415470T/pt unknown
- 2010-03-30 ME MEP-2016-188A patent/ME02518B/me unknown
- 2010-03-30 PE PE2011001735A patent/PE20120923A1/es not_active Application Discontinuation
- 2010-03-30 DK DK10758755.2T patent/DK2415470T3/en active
- 2010-03-30 AU AU2010232347A patent/AU2010232347A1/en not_active Abandoned
- 2010-03-30 NZ NZ595212A patent/NZ595212A/en unknown
- 2010-03-30 US US13/260,872 patent/US20120058178A1/en not_active Abandoned
- 2010-03-30 MY MYPI2011004382A patent/MY160203A/en unknown
- 2010-03-30 PE PE2015001798A patent/PE20151519A1/es unknown
- 2010-03-30 MA MA34174A patent/MA33127B1/fr unknown
- 2010-03-30 CA CA2756811A patent/CA2756811C/en active Active
- 2010-03-30 HU HUE10758755A patent/HUE029577T2/en unknown
- 2010-03-30 ES ES10758755.2T patent/ES2593027T3/es active Active
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2011
- 2011-09-07 ZA ZA2011/06535A patent/ZA201106535B/en unknown
- 2011-09-08 IL IL215059A patent/IL215059A/en active IP Right Grant
- 2011-10-04 CO CO11130828A patent/CO6430500A2/es active IP Right Grant
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2012
- 2012-06-29 HK HK12106366.9A patent/HK1165707A1/zh unknown
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2013
- 2013-10-23 US US14/061,426 patent/US20140044777A1/en active Pending
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2016
- 2016-09-08 SM SM201600307T patent/SMT201600307B/it unknown
- 2016-09-08 HR HRP20161157TT patent/HRP20161157T1/hr unknown
- 2016-09-14 CY CY20161100911T patent/CY1118231T1/el unknown
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2020
- 2020-10-09 US US17/067,302 patent/US11071713B2/en active Active
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