SG10202107836SA - Hyperstabilized liposomes increase targeting of mitotic cells - Google Patents
Hyperstabilized liposomes increase targeting of mitotic cellsInfo
- Publication number
- SG10202107836SA SG10202107836SA SG10202107836SA SG10202107836SA SG10202107836SA SG 10202107836S A SG10202107836S A SG 10202107836SA SG 10202107836S A SG10202107836S A SG 10202107836SA SG 10202107836S A SG10202107836S A SG 10202107836SA SG 10202107836S A SG10202107836S A SG 10202107836SA
- Authority
- SG
- Singapore
- Prior art keywords
- hyperstabilized
- mitotic cells
- increase targeting
- liposomes increase
- liposomes
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title 1
- 230000000394 mitotic effect Effects 0.000 title 1
- 230000008685 targeting Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762447498P | 2017-01-18 | 2017-01-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202107836SA true SG10202107836SA (en) | 2021-08-30 |
Family
ID=62909275
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201906539YA SG11201906539YA (en) | 2017-01-18 | 2018-01-17 | Hyperstabilized liposomes increase targeting of mitotic cells |
| SG10202107836SA SG10202107836SA (en) | 2017-01-18 | 2018-01-17 | Hyperstabilized liposomes increase targeting of mitotic cells |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201906539YA SG11201906539YA (en) | 2017-01-18 | 2018-01-17 | Hyperstabilized liposomes increase targeting of mitotic cells |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11331272B2 (en) |
| EP (1) | EP3570818B1 (en) |
| JP (2) | JP7232530B2 (en) |
| KR (1) | KR20190122676A (en) |
| CN (1) | CN110381922A (en) |
| AU (1) | AU2018210748B2 (en) |
| BR (1) | BR112019014718A2 (en) |
| CA (1) | CA3050686A1 (en) |
| CL (1) | CL2019002002A1 (en) |
| CO (1) | CO2019008876A2 (en) |
| IL (1) | IL268099B2 (en) |
| MA (1) | MA47319A (en) |
| MX (1) | MX2019008533A (en) |
| PH (1) | PH12019501650A1 (en) |
| RU (1) | RU2765736C2 (en) |
| SG (2) | SG11201906539YA (en) |
| TW (1) | TWI816656B (en) |
| WO (1) | WO2018136002A1 (en) |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0768117B2 (en) * | 1983-05-06 | 1995-07-26 | ベスター・インコーポレイテツド | Vesicle formulation for controlled drug release |
| CA1338702C (en) | 1987-03-05 | 1996-11-12 | Lawrence D. Mayer | High drug:lipid formulations of liposomal- antineoplastic agents |
| US5714163A (en) * | 1994-06-27 | 1998-02-03 | Nexstar Pharmaceuticals, Inc. | Vinca alkaloid vesicles with enhanced efficacy and tumor targeting properties |
| US6120800A (en) * | 1997-09-25 | 2000-09-19 | Nexstar Pharmaceuticals, Inc. | Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties |
| WO2003032947A2 (en) * | 2001-09-06 | 2003-04-24 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | A method for preparing liposome formulations with a predefined release profile |
| UA86063C2 (en) | 2004-05-03 | 2009-03-25 | Хермес Біосайенсез, Інк. | Liposomes useful for drug delivery |
| EP1829526B1 (en) | 2004-11-02 | 2016-01-20 | National University Corporation Tokyo Medical and Dental University | Liposome and method of injecting substance into cell by using the same |
| CN101209243B (en) * | 2006-12-29 | 2010-12-08 | 石药集团中奇制药技术（石家庄）有限公司 | Liposome medicament and preparation thereof |
| US20110033461A1 (en) * | 2008-03-12 | 2011-02-10 | Vladimir Ratushny | Combination Therapy for the Treatment of Cancer |
| US20090285881A1 (en) * | 2008-04-16 | 2009-11-19 | Abbott Laboratories | Cationic lipids and uses thereof |
| US8318817B2 (en) * | 2008-07-21 | 2012-11-27 | Otonomy, Inc. | Controlled release antimicrobial compositions and methods for the treatment of otic disorders |
| KR101495951B1 (en) | 2009-03-30 | 2015-02-25 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | Liposome composition |
| CN102458996B (en) | 2009-04-17 | 2016-11-16 | 3M创新有限公司 | There is the lighting protection plate of patterned conductor |
| US9220682B2 (en) * | 2009-04-22 | 2015-12-29 | Emory University | Nanocarrier therapy for treating invasive tumors |
| WO2010143972A2 (en) * | 2009-06-08 | 2010-12-16 | Epitarget As | Acoustically sensitive drug delivery particles comprising non-lamellar forming lipids |
| US20120301537A1 (en) * | 2011-05-23 | 2012-11-29 | Delta-Fly Pharma, Inc. | LIPOSOME CONTAINING shRNA MOLECULE TARGETING A THYMIDYLATE SYNTHASE AND USE THEREOF |
| EP2773426B1 (en) * | 2011-10-31 | 2018-08-22 | Mallinckrodt LLC | Combinational liposome compositions for cancer therapy |
| KR102554628B1 (en) * | 2013-02-01 | 2023-07-12 | 존원 파마, 인코포레이티드 | Remote loading of sparingly water-soluble drugs into liposomes |
| BR112015022415A2 (en) * | 2013-03-13 | 2017-07-18 | Mallinckrodt Llc | Liposomal cisplatin compositions for cancer therapy |
| BR112015023481B1 (en) * | 2013-03-15 | 2022-12-20 | Tlc Biopharmaceuticals, Inc. | CONTROL DRUG RELEASE PROFILE DESIGN VIA LIPOSOME COMPOSITION IN BOTH AQUEOUS AND NON-AQUEOUS COMPARTMENTSCROSS-REFERENCE TO RELATED REQUIREMENTS |
| AU2015206628A1 (en) * | 2014-01-14 | 2016-08-25 | The Johns Hopkins University | Liposome compositions encapsulating modified cyclodextrin complexes and uses thereof |
| JP2017516760A (en) * | 2014-04-14 | 2017-06-22 | エンドサイト・インコーポレイテッドＥｎｄｏｃｙｔｅ， Ｉｎｃ． | Drug delivery complex for treating resistant cancer and for use in combination therapy |
| US20160175250A1 (en) * | 2014-12-23 | 2016-06-23 | Tolmar Inc. | Method for Making Liposomes Containing an Active Pharmaceutical Ingredient |
| KR20170132152A (en) * | 2015-02-13 | 2017-12-01 | 오피 나노 컴퍼니, 리미티드 | Compositions and methods for treating tumors using nanoparticles |
-
2018
- 2018-01-17 CA CA3050686A patent/CA3050686A1/en active Pending
- 2018-01-17 RU RU2019125724A patent/RU2765736C2/en active
- 2018-01-17 AU AU2018210748A patent/AU2018210748B2/en active Active
- 2018-01-17 JP JP2019559257A patent/JP7232530B2/en active Active
- 2018-01-17 KR KR1020197024196A patent/KR20190122676A/en active IP Right Grant
- 2018-01-17 MA MA047319A patent/MA47319A/en unknown
- 2018-01-17 WO PCT/SG2018/050026 patent/WO2018136002A1/en unknown
- 2018-01-17 US US16/478,278 patent/US11331272B2/en active Active
- 2018-01-17 IL IL268099A patent/IL268099B2/en unknown
- 2018-01-17 EP EP18741815.7A patent/EP3570818B1/en active Active
- 2018-01-17 MX MX2019008533A patent/MX2019008533A/en unknown
- 2018-01-17 SG SG11201906539YA patent/SG11201906539YA/en unknown
- 2018-01-17 SG SG10202107836SA patent/SG10202107836SA/en unknown
- 2018-01-17 BR BR112019014718-7A patent/BR112019014718A2/en active Search and Examination
- 2018-01-17 CN CN201880012370.3A patent/CN110381922A/en active Pending
- 2018-01-18 TW TW107101914A patent/TWI816656B/en active
-
2019
- 2019-07-16 PH PH12019501650A patent/PH12019501650A1/en unknown
- 2019-07-17 CL CL2019002002A patent/CL2019002002A1/en unknown
- 2019-08-15 CO CONC2019/0008876A patent/CO2019008876A2/en unknown
-
2022
- 2022-10-20 JP JP2022168560A patent/JP2023002702A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| IL268099B2 (en) | 2024-05-01 |
| JP2023002702A (en) | 2023-01-10 |
| CN110381922A (en) | 2019-10-25 |
| US20190358161A1 (en) | 2019-11-28 |
| RU2019125724A3 (en) | 2021-03-04 |
| RU2765736C2 (en) | 2022-02-02 |
| JP2020505451A (en) | 2020-02-20 |
| JP7232530B2 (en) | 2023-03-03 |
| KR20190122676A (en) | 2019-10-30 |
| MX2019008533A (en) | 2019-12-02 |
| IL268099B1 (en) | 2024-01-01 |
| TW201828925A (en) | 2018-08-16 |
| AU2018210748A1 (en) | 2019-08-29 |
| AU2018210748B2 (en) | 2023-09-28 |
| EP3570818B1 (en) | 2023-11-01 |
| WO2018136002A1 (en) | 2018-07-26 |
| CO2019008876A2 (en) | 2020-01-17 |
| EP3570818A4 (en) | 2020-11-18 |
| MA47319A (en) | 2019-11-27 |
| TWI816656B (en) | 2023-10-01 |
| PH12019501650A1 (en) | 2020-02-24 |
| US11331272B2 (en) | 2022-05-17 |
| CA3050686A1 (en) | 2018-07-26 |
| EP3570818A1 (en) | 2019-11-27 |
| RU2019125724A (en) | 2021-02-19 |
| SG11201906539YA (en) | 2019-08-27 |
| BR112019014718A2 (en) | 2020-03-10 |
| IL268099A (en) | 2019-09-26 |
| CL2019002002A1 (en) | 2020-01-17 |
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