DK323687D0 - Insulinprecursorer og fremgangsmaade til fremstilling deraf - Google Patents

Insulinprecursorer og fremgangsmaade til fremstilling deraf

Info

Publication number
DK323687D0
DK323687D0 DK323687A DK323687A DK323687D0 DK 323687 D0 DK323687 D0 DK 323687D0 DK 323687 A DK323687 A DK 323687A DK 323687 A DK323687 A DK 323687A DK 323687 D0 DK323687 D0 DK 323687D0
Authority
DK
Denmark
Prior art keywords
chain
insulin
human insulin
bridging
lys
Prior art date
Application number
DK323687A
Other languages
English (en)
Other versions
DK157933B (da
DK323687A (da
DK157933C (da
Inventor
Jan Markussen
Niels Fiil
Mogens Trier Hansen
Lars Thim
Kjeld Norris
Hans Ole Voigt
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26064247&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK323687(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DK266584A external-priority patent/DK266584D0/da
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK323687A priority Critical patent/DK157933C/da
Publication of DK323687D0 publication Critical patent/DK323687D0/da
Publication of DK323687A publication Critical patent/DK323687A/da
Publication of DK157933B publication Critical patent/DK157933B/da
Application granted granted Critical
Publication of DK157933C publication Critical patent/DK157933C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/69—Increasing the copy number of the vector
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces
    • Y10S435/942—Saccharomyces cerevisiae

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK323687A 1984-05-30 1987-06-25 Insulinprecursorer DK157933C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK323687A DK157933C (da) 1984-05-30 1987-06-25 Insulinprecursorer

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK266584A DK266584D0 (da) 1984-05-30 1984-05-30 Dna-sekvens, der koder for en biosyntetisk insulinprecursor og fremgangsmaade til fremstilling af insulinprecursoren
DK266584 1984-05-30
DK58285A DK58285D0 (da) 1984-05-30 1985-02-08 Peptider samt fremstilling og anvendelse deraf
DK58285 1985-02-08
DK323687A DK157933C (da) 1984-05-30 1987-06-25 Insulinprecursorer
DK323687 1987-06-25

Publications (4)

Publication Number Publication Date
DK323687D0 true DK323687D0 (da) 1987-06-25
DK323687A DK323687A (da) 1987-06-25
DK157933B DK157933B (da) 1990-03-05
DK157933C DK157933C (da) 1990-08-27

Family

ID=26064247

Family Applications (2)

Application Number Title Priority Date Filing Date
DK58285A DK58285D0 (da) 1984-05-30 1985-02-08 Peptider samt fremstilling og anvendelse deraf
DK323687A DK157933C (da) 1984-05-30 1987-06-25 Insulinprecursorer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK58285A DK58285D0 (da) 1984-05-30 1985-02-08 Peptider samt fremstilling og anvendelse deraf

Country Status (15)

Country Link
US (1) US4916212A (da)
EP (2) EP0163529B1 (da)
JP (4) JPH0630613B2 (da)
AT (1) ATE143374T1 (da)
AU (1) AU590197B2 (da)
CA (1) CA1304022C (da)
DE (2) DE3588125T2 (da)
DK (2) DK58285D0 (da)
ES (2) ES8609483A1 (da)
FI (1) FI89183C (da)
GR (1) GR851304B (da)
IE (1) IE66387B1 (da)
NO (1) NO174351C (da)
NZ (1) NZ212243A (da)
PT (1) PT80551B (da)

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JPS58183659A (ja) * 1982-03-31 1983-10-26 ジェネテイックス、インスチチュ−ト、インコ−ポレ−テッド 修飾プロインシュリン前駆体、これを暗号化するｄｎａ配列およびそれらの産生方法
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EP0243465A1 (en) * 1985-10-25 1987-11-04 Vivian L. Mackay Method of using bar1 for secreting foreign proteins

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DK157933B (da) 1990-03-05
FI852135A0 (fi) 1985-05-29
JPH06141865A (ja) 1994-05-24
JPH06141866A (ja) 1994-05-24
DK323687A (da) 1987-06-25
DE3588125D1 (de) 1996-10-31
DK58285D0 (da) 1985-02-08
DE3588125T2 (de) 1997-02-13
JP2519023B2 (ja) 1996-07-31
ATE143374T1 (de) 1996-10-15
IE851331L (en) 1985-11-30
NO174351B (no) 1994-01-10
NZ212243A (en) 1988-05-30
DE3583824D1 (de) 1991-09-26
EP0427296A1 (en) 1991-05-15
EP0163529B1 (en) 1991-08-21
JPH0746998B2 (ja) 1995-05-24
JPS611389A (ja) 1986-01-07
JPH0630613B2 (ja) 1994-04-27
JPH07309896A (ja) 1995-11-28
ES8702488A1 (es) 1986-12-16
PT80551A (en) 1985-06-01
FI89183B (fi) 1993-05-14
CA1304022C (en) 1992-06-23
NO174351C (no) 1994-04-20
AU4309285A (en) 1985-12-05
DK157933C (da) 1990-08-27
IE66387B1 (en) 1995-12-27
AU590197B2 (en) 1989-11-02
ES543594A0 (es) 1986-09-01
GR851304B (da) 1985-11-25
FI89183C (fi) 1993-08-25
ES8609483A1 (es) 1986-09-01
ES551941A0 (es) 1986-12-16
FI852135L (fi) 1985-12-01
US4916212A (en) 1990-04-10
PT80551B (en) 1987-04-09
JPH07121226B2 (ja) 1995-12-25
NO852132L (no) 1985-12-02
EP0163529A1 (en) 1985-12-04
EP0427296B1 (en) 1996-09-25

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