DK3169706T3 - Antistoffer, der binder axl - Google Patents

Antistoffer, der binder axl Download PDF

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Publication number
DK3169706T3
DK3169706T3 DK15738884.4T DK15738884T DK3169706T3 DK 3169706 T3 DK3169706 T3 DK 3169706T3 DK 15738884 T DK15738884 T DK 15738884T DK 3169706 T3 DK3169706 T3 DK 3169706T3
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DK
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Prior art keywords
axl
antibodies
binder
binder axl
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DK15738884.4T
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Danish (da)
English (en)
Inventor
Esther Breij
David Satijn
Den Brink Edward Norbert Van
Dennis Verzijl
Jong Rob N De
Paul Parren
Dijkhuizen Radersma Riemke Van
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Genmab As
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Publication of DK3169706T3 publication Critical patent/DK3169706T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/77—Internalization into the cell
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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WO2016005593A1 (en) 2016-01-14
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KR102586656B1 (ko) 2023-10-11
CY1122721T1 (el) 2021-03-12
EP3169706A1 (en) 2017-05-24
ZA201608609B (en) 2020-12-23
CN107074948B (zh) 2022-01-28
SG11201610777VA (en) 2017-01-27
AU2021205074B2 (en) 2024-12-12
AU2015286569B2 (en) 2021-04-15
PT3169706T (pt) 2020-03-13
EP3169706B1 (en) 2019-12-04
ME03665B (me) 2020-10-20
UA127198C2 (uk) 2023-06-07
AU2025201717A1 (en) 2025-03-27
JP2024026158A (ja) 2024-02-28
US10500276B2 (en) 2019-12-10
HUE048667T2 (hu) 2020-08-28
NZ766131A (en) 2024-07-05
IL249512A0 (en) 2017-02-28
SG10202006715SA (en) 2020-08-28
AU2021205074A1 (en) 2021-08-12
ES2774428T3 (es) 2020-07-21
HRP20200283T1 (hr) 2020-05-29
IL296633A (en) 2022-11-01
US20190160170A1 (en) 2019-05-30
LT3169706T (lt) 2020-03-25
RS60012B1 (sr) 2020-04-30
US20170157250A1 (en) 2017-06-08
US20240091352A1 (en) 2024-03-21
US10201607B2 (en) 2019-02-12
JP2017522871A (ja) 2017-08-17
AU2015286569A1 (en) 2017-02-02
KR20230146665A (ko) 2023-10-19
MX2016016881A (es) 2017-03-27
IL249512B (en) 2022-10-01
JP2020141682A (ja) 2020-09-10
EA201790173A1 (ru) 2017-06-30
US20180214549A1 (en) 2018-08-02
BR112017000316A2 (pt) 2017-10-31
US20190275149A1 (en) 2019-09-12
MX370807B (es) 2020-01-08

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