DK2803720T3 - Mikroorganismer fra escherichia coli med forbedret produktion af l-tryptofan og fremgangsmåde til fremstilling af l-tryptofan dermed - Google Patents
Mikroorganismer fra escherichia coli med forbedret produktion af l-tryptofan og fremgangsmåde til fremstilling af l-tryptofan dermed Download PDFInfo
- Publication number
- DK2803720T3 DK2803720T3 DK13735653.1T DK13735653T DK2803720T3 DK 2803720 T3 DK2803720 T3 DK 2803720T3 DK 13735653 T DK13735653 T DK 13735653T DK 2803720 T3 DK2803720 T3 DK 2803720T3
- Authority
- DK
- Denmark
- Prior art keywords
- tryptofan
- tryptophane
- organisms
- procedure
- production
- Prior art date
Links
- 241000588724 Escherichia coli Species 0.000 title 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
- 229960004799 tryptophan Drugs 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
-
- H—ELECTRICITY
- H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
- H10K—ORGANIC ELECTRIC SOLID-STATE DEVICES
- H10K59/00—Integrated devices, or assemblies of multiple devices, comprising at least one organic light-emitting element covered by group H10K50/00
- H10K59/10—OLED displays
- H10K59/12—Active-matrix OLED [AMOLED] displays
- H10K59/131—Interconnections, e.g. wiring lines or terminals
-
- H—ELECTRICITY
- H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
- H10K—ORGANIC ELECTRIC SOLID-STATE DEVICES
- H10K50/00—Organic light-emitting devices
- H10K50/80—Constructional details
- H10K50/805—Electrodes
- H10K50/82—Cathodes
- H10K50/826—Multilayers, e.g. opaque multilayers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20120002906 | 2012-01-10 | ||
| PCT/KR2013/000214 WO2013105800A2 (ko) | 2012-01-10 | 2013-01-10 | L-트립토판 생산능이 강화된 에스케리키아속 미생물 및 이를 이용하여 l-트립토판을 생산하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2803720T3 true DK2803720T3 (da) | 2022-04-04 |
Family
ID=48993539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13735653.1T DK2803720T3 (da) | 2012-01-10 | 2013-01-10 | Mikroorganismer fra escherichia coli med forbedret produktion af l-tryptofan og fremgangsmåde til fremstilling af l-tryptofan dermed |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9587261B2 (da) |
| EP (1) | EP2803720B1 (da) |
| JP (2) | JP6449653B2 (da) |
| KR (3) | KR101532129B1 (da) |
| BR (1) | BR112014017074B1 (da) |
| CA (1) | CA2860974C (da) |
| DK (1) | DK2803720T3 (da) |
| ES (1) | ES2910377T3 (da) |
| HU (1) | HUE057864T2 (da) |
| MX (1) | MX351721B (da) |
| MY (1) | MY173848A (da) |
| PH (1) | PH12014501590A1 (da) |
| RU (1) | RU2593957C2 (da) |
| WO (1) | WO2013105800A2 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2593957C2 (ru) * | 2012-01-10 | 2016-08-10 | СиДжей ЧЕИЛДЗЕДАНГ КОРПОРЕЙШН | МИКРООРГАНИЗМ ИЗ РОДА Escherichia, ОБЛАДАЮЩИЙ УСИЛЕННОЙ СПОСОБНОСТЬЮ К ПРОДУКЦИИ L-ТРИПТОФАНА, И СПОСОБ ПОЛУЧЕНИЯ L-ТРИПТОФАНА С ЕГО ИСПОЛЬЗОВАНИЕМ |
| KR101835173B1 (ko) * | 2014-06-23 | 2018-03-07 | 씨제이제일제당 (주) | L-트립토판 생산능을 갖는 에스케리키아속 미생물 및 이를 이용한 l-트립토판의 제조 방법 |
| KR101835935B1 (ko) * | 2014-10-13 | 2018-03-12 | 씨제이제일제당 (주) | L-아르기닌을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아르기닌의 제조 방법 |
| KR101704199B1 (ko) * | 2015-05-14 | 2017-02-08 | 씨제이제일제당 (주) | L-트립토판 생산능을 갖는 에스케리키아속 미생물 및 이를 이용한 l-트립토판의 제조 방법 |
| KR101704198B1 (ko) | 2015-05-14 | 2017-02-08 | 씨제이제일제당 (주) | L-트립토판 생산능을 갖는 에스케리키아속 미생물 및 이를 이용한 l-트립토판의 제조 방법 |
| WO2017136795A1 (en) * | 2016-02-04 | 2017-08-10 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with tryptophan metabolism |
| US10947523B2 (en) | 2017-11-15 | 2021-03-16 | Technische Universitaet Hamburg | Biotechnological production of L-tryptophan |
| KR102035844B1 (ko) * | 2018-02-23 | 2019-10-23 | 씨제이제일제당 주식회사 | L-트립토판을 생산하는 재조합 코리네형 미생물 및 이를 이용한 l-트립토판을 생산하는 방법 |
| BR112020018947B1 (pt) | 2018-03-23 | 2023-05-02 | Cj Cheiljedang Corporation | Grânulos que compreendem l-aminoácido e método para preparar os mesmos |
| US11053526B2 (en) | 2018-08-09 | 2021-07-06 | Evonik Operations Gmbh | Process for preparing L amino acids using improved strains of the enterobacteriaceae family |
| KR101991206B1 (ko) | 2018-11-29 | 2019-06-19 | 씨제이제일제당 (주) | cAMP 수용 단백질 변이체 및 이를 이용한 L-아미노산 제조방법 |
| KR101996767B1 (ko) | 2018-11-29 | 2019-07-04 | 씨제이제일제당 (주) | cAMP 수용 단백질 변이체 및 이를 이용한 L-아미노산 제조방법 |
| KR101991207B1 (ko) | 2018-11-29 | 2019-06-19 | 씨제이제일제당 (주) | cAMP 수용 단백질 변이체 및 이를 이용한 L-아미노산 제조방법 |
| EP3677594A1 (en) * | 2019-01-07 | 2020-07-08 | Evonik Operations GmbH | Method for producing l-tryptophan using improved strains of the enterobacteriaceae family |
| KR102205717B1 (ko) * | 2019-04-05 | 2021-01-22 | 씨제이제일제당 주식회사 | 신규 l-트립토판 배출 단백질 변이체 및 이를 이용한 l-트립토판을 생산하는 방법 |
| KR102134418B1 (ko) * | 2019-06-17 | 2020-07-16 | 씨제이제일제당 주식회사 | L-타이로신을 생산하는 미생물 및 이를 이용한 l-타이로신 생산 방법 |
| CN116033831A (zh) | 2020-06-26 | 2023-04-28 | Cj第一制糖株式会社 | 从发酵液制造氨基酸颗粒的方法 |
| CN117660448B (zh) * | 2023-11-09 | 2024-10-18 | 江苏集萃未来食品技术研究所有限公司 | 一种产l-色氨酸菌株的高通量筛选方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4371614A (en) | 1980-08-22 | 1983-02-01 | Ajinomoto Co., Inc. | E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan |
| EP0113372A1 (en) | 1982-07-13 | 1984-07-18 | Celltech Limited | Vector |
| KR850001232B1 (ko) | 1983-12-09 | 1985-08-23 | 제일제당 주식회사 | 발효에 의한 l-페닐알라닌의 제조방법 |
| JPS619287A (ja) | 1984-06-22 | 1986-01-16 | Hitachi Ltd | 複合プラスミド及びそれを保持する微生物 |
| KR870001813B1 (ko) | 1985-05-20 | 1987-10-13 | 한국과학기술원 | 발효법에 의한 l-트립토판의 제조방법 |
| WO1987001130A1 (en) * | 1985-08-15 | 1987-02-26 | Stauffer Chemical Company | Tryptophan producing microorganism |
| EP0293207A3 (en) * | 1987-05-29 | 1989-11-02 | The Standard Oil Company | Eschericia coli carrying recombinant plasmid for the production of tryptophan |
| DE4232468A1 (de) * | 1992-09-28 | 1994-03-31 | Consortium Elektrochem Ind | Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung |
| GB2304718B (en) * | 1995-09-05 | 2000-01-19 | Degussa | The production of tryptophan by the bacterium escherichia coli |
| JP2002209596A (ja) * | 2001-01-19 | 2002-07-30 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP4380305B2 (ja) * | 2003-11-21 | 2009-12-09 | 味の素株式会社 | 発酵法によるｌ−アミノ酸の製造法 |
| JP2010017081A (ja) | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| KR100792095B1 (ko) * | 2006-12-29 | 2008-01-04 | 씨제이 주식회사 | Ｌ-페닐알라닌 생산능을 갖는 대장균 변이주로부터유전자조작된 ｌ-트립토판 생산능을 갖는 재조합 대장균균주 및 이를 이용한 트립토판 제조방법 |
| RU2395567C2 (ru) * | 2007-03-22 | 2010-07-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ОДИН ИЛИ НЕСКОЛЬКО ГЕНОВ, КОДИРУЮЩИХ МАЛЫЕ РНК |
| KR100949312B1 (ko) | 2007-12-20 | 2010-03-23 | 씨제이제일제당 (주) | 안스라닐산염에 대한 내성을 갖는 대장균 균주를 이용한ｌ-트립토판 제조 방법 |
| KR20090075549A (ko) | 2008-01-04 | 2009-07-08 | 씨제이제일제당 (주) | 향상된 ｌ-쓰레오닌 생산능을 갖는 대장균 및 이를 이용한ｌ-쓰레오닌의 생산 방법 |
| RU2593957C2 (ru) * | 2012-01-10 | 2016-08-10 | СиДжей ЧЕИЛДЗЕДАНГ КОРПОРЕЙШН | МИКРООРГАНИЗМ ИЗ РОДА Escherichia, ОБЛАДАЮЩИЙ УСИЛЕННОЙ СПОСОБНОСТЬЮ К ПРОДУКЦИИ L-ТРИПТОФАНА, И СПОСОБ ПОЛУЧЕНИЯ L-ТРИПТОФАНА С ЕГО ИСПОЛЬЗОВАНИЕМ |
-
2013
- 2013-01-10 RU RU2014132889/10A patent/RU2593957C2/ru active
- 2013-01-10 CA CA2860974A patent/CA2860974C/en active Active
- 2013-01-10 ES ES13735653T patent/ES2910377T3/es active Active
- 2013-01-10 KR KR1020130002913A patent/KR101532129B1/ko active IP Right Grant
- 2013-01-10 HU HUE13735653A patent/HUE057864T2/hu unknown
- 2013-01-10 MX MX2014008470A patent/MX351721B/es active IP Right Grant
- 2013-01-10 WO PCT/KR2013/000214 patent/WO2013105800A2/ko active Application Filing
- 2013-01-10 DK DK13735653.1T patent/DK2803720T3/da active
- 2013-01-10 US US14/371,465 patent/US9587261B2/en active Active
- 2013-01-10 EP EP13735653.1A patent/EP2803720B1/en active Active
- 2013-01-10 BR BR112014017074-6A patent/BR112014017074B1/pt active IP Right Grant
- 2013-01-10 JP JP2014552128A patent/JP6449653B2/ja active Active
- 2013-01-10 MY MYPI2014002060A patent/MY173848A/en unknown
-
2014
- 2014-07-10 PH PH12014501590A patent/PH12014501590A1/en unknown
-
2015
- 2015-05-18 KR KR1020150068980A patent/KR101886480B1/ko active IP Right Grant
-
2016
- 2016-05-10 KR KR1020160057013A patent/KR101629159B1/ko active IP Right Grant
- 2016-07-04 JP JP2016132893A patent/JP6475668B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014132889A (ru) | 2016-02-27 |
| MY173848A (en) | 2020-02-24 |
| EP2803720A4 (en) | 2016-04-06 |
| US20150147788A1 (en) | 2015-05-28 |
| JP6475668B2 (ja) | 2019-02-27 |
| KR101532129B1 (ko) | 2015-06-29 |
| CN104204189A (zh) | 2014-12-10 |
| WO2013105800A2 (ko) | 2013-07-18 |
| EP2803720A2 (en) | 2014-11-19 |
| JP2015503358A (ja) | 2015-02-02 |
| HUE057864T2 (hu) | 2022-06-28 |
| MX2014008470A (es) | 2014-11-10 |
| US9587261B2 (en) | 2017-03-07 |
| JP2017018094A (ja) | 2017-01-26 |
| BR112014017074B1 (pt) | 2022-05-10 |
| CA2860974A1 (en) | 2013-07-18 |
| EP2803720B1 (en) | 2022-03-09 |
| KR20150061626A (ko) | 2015-06-04 |
| KR101886480B1 (ko) | 2018-08-07 |
| RU2593957C2 (ru) | 2016-08-10 |
| MX351721B (es) | 2017-10-25 |
| WO2013105800A3 (ko) | 2013-10-17 |
| BR112014017074A2 (pt) | 2020-10-27 |
| PH12014501590A1 (en) | 2014-10-08 |
| CA2860974C (en) | 2019-03-05 |
| KR20130082121A (ko) | 2013-07-18 |
| KR20160058077A (ko) | 2016-05-24 |
| ES2910377T3 (es) | 2022-05-12 |
| JP6449653B2 (ja) | 2019-01-09 |
| KR101629159B1 (ko) | 2016-06-09 |
| WO2013105800A9 (ko) | 2013-08-29 |
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