DK3326642T3 - Langtidsvirkende koagulationsfaktorer og brugen deraf - Google Patents

Langtidsvirkende koagulationsfaktorer og brugen deraf Download PDF

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Publication number
DK3326642T3
DK3326642T3 DK18150731.0T DK18150731T DK3326642T3 DK 3326642 T3 DK3326642 T3 DK 3326642T3 DK 18150731 T DK18150731 T DK 18150731T DK 3326642 T3 DK3326642 T3 DK 3326642T3
Authority
DK
Denmark
Prior art keywords
coopulation
factors
term
long
term coopulation
Prior art date
Application number
DK18150731.0T
Other languages
English (en)
Inventor
Udi Eyal Fima
Gili Hart
Original Assignee
Opko Biologics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48983616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3326642(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US13/372,540 external-priority patent/US8759292B2/en
Application filed by Opko Biologics Ltd filed Critical Opko Biologics Ltd
Application granted granted Critical
Publication of DK3326642T3 publication Critical patent/DK3326642T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Glass Compositions (AREA)
DK18150731.0T 2012-02-14 2013-02-05 Langtidsvirkende koagulationsfaktorer og brugen deraf DK3326642T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/372,540 US8759292B2 (en) 2006-02-03 2012-02-14 Long-acting coagulation factors and methods of producing same
EP13749077.7A EP2822576B1 (en) 2012-02-14 2013-02-05 Long-acting coagulation factors and methods of producing same

Publications (1)

Publication Number Publication Date
DK3326642T3 true DK3326642T3 (da) 2021-02-22

Family

ID=48983616

Family Applications (2)

Application Number Title Priority Date Filing Date
DK18150731.0T DK3326642T3 (da) 2012-02-14 2013-02-05 Langtidsvirkende koagulationsfaktorer og brugen deraf
DK13749077.7T DK2822576T3 (da) 2012-02-14 2013-02-05 Langtidsvirkende koagulationsfaktorer og fremgangsmåder til fremstilling heraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK13749077.7T DK2822576T3 (da) 2012-02-14 2013-02-05 Langtidsvirkende koagulationsfaktorer og fremgangsmåder til fremstilling heraf

Country Status (22)

Country Link
EP (3) EP3326642B1 (da)
JP (2) JP6242819B2 (da)
KR (3) KR102310704B1 (da)
CN (2) CN104427994A (da)
AU (3) AU2013219935B2 (da)
BR (1) BR122021004014B1 (da)
CA (1) CA2870621C (da)
CL (2) CL2014002183A1 (da)
CO (1) CO7131365A2 (da)
DK (2) DK3326642T3 (da)
EA (2) EA028578B1 (da)
ES (2) ES2855133T3 (da)
HK (1) HK1205460A1 (da)
HU (1) HUE053068T2 (da)
IL (2) IL264959B (da)
MX (3) MX362446B (da)
MY (1) MY172539A (da)
NO (1) NO2920022T3 (da)
PE (1) PE20142290A1 (da)
PL (1) PL3326642T3 (da)
SG (1) SG11201404836QA (da)
WO (1) WO2013121416A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
DK3326642T3 (da) * 2012-02-14 2021-02-22 Opko Biologics Ltd Langtidsvirkende koagulationsfaktorer og brugen deraf
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
KR102527180B1 (ko) * 2014-12-10 2023-04-27 옵코 바이오로직스 리미티드 장기간 작용성 ctp-변형된 성장 호르몬 폴리펩타이드의 제조 방법
EP3310347B1 (en) * 2015-06-19 2021-08-04 OPKO Biologics Ltd. Long-acting coagulation factors and methods of producing same
UA126016C2 (uk) 2015-08-03 2022-08-03 Біовератів Терапеутікс Інк. Злитий білок фактора іх
KR20240006077A (ko) * 2016-07-11 2024-01-12 옵코 바이오로직스 리미티드 지속성 응고 인자 vii 및 그 제조 방법
CN107759694B (zh) 2016-08-19 2023-01-13 安源医药科技（上海）有限公司 双特异性抗体及其制备方法与用途
US11123438B2 (en) 2016-08-19 2021-09-21 Ampsource Biopharma Shanghai Inc. Linker peptide for constructing fusion protein
CN106279437B (zh) * 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
WO2018163586A1 (ja) 2017-03-08 2018-09-13 テイ・エス テック株式会社 乗物用シート
US11981718B2 (en) 2020-05-27 2024-05-14 Ampsource Biopharma Shanghai Inc. Dual-function protein for lipid and blood glucose regulation

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US8759292B2 (en) * 2006-02-03 2014-06-24 Prolor Biotech, Llc Long-acting coagulation factors and methods of producing same
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TWI538916B (zh) * 2008-04-11 2016-06-21 介控生化科技公司 經修飾的因子vii多肽和其用途
JP5977945B2 (ja) * 2008-08-06 2016-08-24 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 長期のインビボ有効性を有するコンジュゲートタンパク質
DK3326642T3 (da) * 2012-02-14 2021-02-22 Opko Biologics Ltd Langtidsvirkende koagulationsfaktorer og brugen deraf
CN112661863A (zh) * 2012-11-20 2021-04-16 奥普科生物制品有限公司 通过连接至促性腺激素羧基端肽来增加多肽的流体动力学体积的方法

Also Published As

Publication number Publication date
EP2822576A4 (en) 2015-11-25
AU2016202829B2 (en) 2017-05-25
CN104427994A (zh) 2015-03-18
MY172539A (en) 2019-11-30
CA2870621C (en) 2022-08-09
EP2822576A1 (en) 2015-01-14
AU2017219044A1 (en) 2017-09-14
CL2017002233A1 (es) 2018-05-11
ES2855133T3 (es) 2021-09-23
WO2013121416A1 (en) 2013-08-22
EA201790960A2 (ru) 2017-09-29
IL264959B (en) 2021-08-31
JP6510002B2 (ja) 2019-05-08
KR20200063274A (ko) 2020-06-04
KR102118729B1 (ko) 2020-06-05
EP3326642A1 (en) 2018-05-30
EP3791890A1 (en) 2021-03-17
AU2017219044B2 (en) 2019-05-30
JP2018065815A (ja) 2018-04-26
IL282121A (en) 2021-05-31
KR20210125595A (ko) 2021-10-18
CL2014002183A1 (es) 2015-01-09
EA028578B1 (ru) 2017-12-29
KR20140134673A (ko) 2014-11-24
JP2015508771A (ja) 2015-03-23
CA2870621A1 (en) 2013-08-22
MX2014009910A (es) 2015-09-28
KR102630953B1 (ko) 2024-01-29
PL3326642T3 (pl) 2021-06-14
BR112014020198A2 (pt) 2018-05-15
IL282121B (en) 2022-06-01
NO2920022T3 (da) 2018-06-09
MX2019000708A (es) 2020-09-02
HK1205460A1 (en) 2015-12-18
EA201491519A1 (ru) 2014-12-30
JP6242819B2 (ja) 2017-12-06
HUE053068T2 (hu) 2021-06-28
AU2013219935A1 (en) 2014-09-25
SG11201404836QA (en) 2014-12-30
CO7131365A2 (es) 2014-12-01
AU2013219935B2 (en) 2016-02-04
EA201790960A3 (ru) 2018-01-31
EP2822576B1 (en) 2018-01-10
DK2822576T3 (da) 2018-04-16
EP3326642B1 (en) 2020-11-25
KR102310704B1 (ko) 2021-10-08
MX2022008807A (es) 2022-08-11
PE20142290A1 (es) 2015-01-15
AU2016202829A1 (en) 2016-05-19
ES2665319T3 (es) 2018-04-25
MX362446B (es) 2019-01-18
CN109535245A (zh) 2019-03-29
BR122021004014B1 (pt) 2022-12-27

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