DK3326642T3 - Langtidsvirkende koagulationsfaktorer og brugen deraf - Google Patents

Langtidsvirkende koagulationsfaktorer og brugen deraf Download PDF

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Publication number
DK3326642T3
DK3326642T3 DK18150731.0T DK18150731T DK3326642T3 DK 3326642 T3 DK3326642 T3 DK 3326642T3 DK 18150731 T DK18150731 T DK 18150731T DK 3326642 T3 DK3326642 T3 DK 3326642T3
Authority
DK
Denmark
Prior art keywords
coopulation
factors
term
long
term coopulation
Prior art date
Application number
DK18150731.0T
Other languages
English (en)
Inventor
Udi Eyal Fima
Gili Hart
Original Assignee
Opko Biologics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48983616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3326642(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US13/372,540 external-priority patent/US8759292B2/en
Application filed by Opko Biologics Ltd filed Critical Opko Biologics Ltd
Application granted granted Critical
Publication of DK3326642T3 publication Critical patent/DK3326642T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
DK18150731.0T 2012-02-14 2013-02-05 Langtidsvirkende koagulationsfaktorer og brugen deraf DK3326642T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/372,540 US8759292B2 (en) 2006-02-03 2012-02-14 Long-acting coagulation factors and methods of producing same
EP13749077.7A EP2822576B1 (en) 2012-02-14 2013-02-05 Long-acting coagulation factors and methods of producing same

Publications (1)

Publication Number Publication Date
DK3326642T3 true DK3326642T3 (da) 2021-02-22

Family

ID=48983616

Family Applications (2)

Application Number Title Priority Date Filing Date
DK13749077.7T DK2822576T3 (da) 2012-02-14 2013-02-05 Langtidsvirkende koagulationsfaktorer og fremgangsmåder til fremstilling heraf
DK18150731.0T DK3326642T3 (da) 2012-02-14 2013-02-05 Langtidsvirkende koagulationsfaktorer og brugen deraf

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK13749077.7T DK2822576T3 (da) 2012-02-14 2013-02-05 Langtidsvirkende koagulationsfaktorer og fremgangsmåder til fremstilling heraf

Country Status (22)

Country Link
EP (3) EP3326642B1 (da)
JP (2) JP6242819B2 (da)
KR (3) KR102630953B1 (da)
CN (2) CN104427994A (da)
AU (3) AU2013219935B2 (da)
BR (1) BR122021004014B1 (da)
CA (1) CA2870621C (da)
CL (2) CL2014002183A1 (da)
CO (1) CO7131365A2 (da)
DK (2) DK2822576T3 (da)
EA (2) EA028578B1 (da)
ES (2) ES2665319T3 (da)
HK (1) HK1205460A1 (da)
HU (1) HUE053068T2 (da)
IL (2) IL264959B (da)
MX (3) MX362446B (da)
MY (1) MY172539A (da)
NO (1) NO2920022T3 (da)
PE (1) PE20142290A1 (da)
PL (1) PL3326642T3 (da)
SG (1) SG11201404836QA (da)
WO (1) WO2013121416A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
JP6242819B2 (ja) * 2012-02-14 2017-12-06 オプコ バイオロジクス リミテッド 長時間作用型凝固因子およびその生成方法
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
AU2015358890B2 (en) 2014-12-10 2019-06-13 Opko Biologics Ltd. Methods of producing long acting CTP-modified growth hormone polypeptides
AU2016280867B2 (en) * 2015-06-19 2020-02-27 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
EA201890423A1 (ru) 2015-08-03 2018-07-31 Биовератив Терапьютикс Инк. Слитые белки фактора ix, способы их получения и применения
ES2963725T3 (es) * 2016-07-11 2024-04-01 Opko Biologics Ltd Factor VII de coagulación de acción prolongada y métodos para producir el mismo
CN106279437B (zh) * 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
US11123438B2 (en) 2016-08-19 2021-09-21 Ampsource Biopharma Shanghai Inc. Linker peptide for constructing fusion protein
CN107759697B (zh) 2016-08-19 2023-03-24 安源医药科技（上海）有限公司 制备融合蛋白的方法
WO2018163586A1 (ja) 2017-03-08 2018-09-13 テイ・エス テック株式会社 乗物用シート

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Also Published As

Publication number Publication date
MX362446B (es) 2019-01-18
EA028578B1 (ru) 2017-12-29
EP3791890A1 (en) 2021-03-17
KR102118729B1 (ko) 2020-06-05
IL264959B (en) 2021-08-31
EP3326642B1 (en) 2020-11-25
MX2014009910A (es) 2015-09-28
CL2014002183A1 (es) 2015-01-09
JP2015508771A (ja) 2015-03-23
ES2855133T3 (es) 2021-09-23
IL282121B (en) 2022-06-01
CA2870621C (en) 2022-08-09
MX2019000708A (es) 2020-09-02
EP3326642A1 (en) 2018-05-30
EA201790960A2 (ru) 2017-09-29
ES2665319T3 (es) 2018-04-25
AU2016202829A1 (en) 2016-05-19
CO7131365A2 (es) 2014-12-01
BR122021004014B1 (pt) 2022-12-27
KR20140134673A (ko) 2014-11-24
KR20200063274A (ko) 2020-06-04
HUE053068T2 (hu) 2021-06-28
CN109535245A (zh) 2019-03-29
CL2017002233A1 (es) 2018-05-11
EA201790960A3 (ru) 2018-01-31
AU2017219044B2 (en) 2019-05-30
EA201491519A1 (ru) 2014-12-30
EP2822576A4 (en) 2015-11-25
KR102630953B1 (ko) 2024-01-29
PL3326642T3 (pl) 2021-06-14
KR20210125595A (ko) 2021-10-18
CA2870621A1 (en) 2013-08-22
CN104427994A (zh) 2015-03-18
WO2013121416A1 (en) 2013-08-22
JP2018065815A (ja) 2018-04-26
HK1205460A1 (en) 2015-12-18
JP6242819B2 (ja) 2017-12-06
BR112014020198A2 (pt) 2018-05-15
AU2013219935A1 (en) 2014-09-25
EP2822576B1 (en) 2018-01-10
SG11201404836QA (en) 2014-12-30
DK2822576T3 (da) 2018-04-16
MY172539A (en) 2019-11-30
NO2920022T3 (da) 2018-06-09
KR102310704B1 (ko) 2021-10-08
IL282121A (en) 2021-05-31
JP6510002B2 (ja) 2019-05-08
AU2016202829B2 (en) 2017-05-25
AU2017219044A1 (en) 2017-09-14
AU2013219935B2 (en) 2016-02-04
PE20142290A1 (es) 2015-01-15
MX2022008807A (es) 2022-08-11
EP2822576A1 (en) 2015-01-14

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