HUE053068T2 - Hosszú hatástartamú koagulációs faktorok és alkalmazásaik - Google Patents

Hosszú hatástartamú koagulációs faktorok és alkalmazásaik

Info

Publication number
HUE053068T2
HUE053068T2 HUE18150731A HUE18150731A HUE053068T2 HU E053068 T2 HUE053068 T2 HU E053068T2 HU E18150731 A HUE18150731 A HU E18150731A HU E18150731 A HUE18150731 A HU E18150731A HU E053068 T2 HUE053068 T2 HU E053068T2
Authority
HU
Hungary
Prior art keywords
long
coagulation factors
acting coagulation
acting
factors
Prior art date
Application number
HUE18150731A
Other languages
English (en)
Inventor
Udi Eyal Fima
Gili Hart
Original Assignee
Opko Biologics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48983616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE053068(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US13/372,540 external-priority patent/US8759292B2/en
Application filed by Opko Biologics Ltd filed Critical Opko Biologics Ltd
Publication of HUE053068T2 publication Critical patent/HUE053068T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Glass Compositions (AREA)
HUE18150731A 2012-02-14 2013-02-05 Hosszú hatástartamú koagulációs faktorok és alkalmazásaik HUE053068T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/372,540 US8759292B2 (en) 2006-02-03 2012-02-14 Long-acting coagulation factors and methods of producing same

Publications (1)

Publication Number Publication Date
HUE053068T2 true HUE053068T2 (hu) 2021-06-28

Family

ID=48983616

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE18150731A HUE053068T2 (hu) 2012-02-14 2013-02-05 Hosszú hatástartamú koagulációs faktorok és alkalmazásaik

Country Status (22)

Country Link
EP (3) EP2822576B1 (hu)
JP (2) JP6242819B2 (hu)
KR (3) KR102310704B1 (hu)
CN (2) CN104427994A (hu)
AU (3) AU2013219935B2 (hu)
BR (1) BR122021004014B1 (hu)
CA (1) CA2870621C (hu)
CL (2) CL2014002183A1 (hu)
CO (1) CO7131365A2 (hu)
DK (2) DK2822576T3 (hu)
EA (2) EA028578B1 (hu)
ES (2) ES2665319T3 (hu)
HK (1) HK1205460A1 (hu)
HU (1) HUE053068T2 (hu)
IL (2) IL264959B (hu)
MX (3) MX362446B (hu)
MY (1) MY172539A (hu)
NO (1) NO2920022T3 (hu)
PE (1) PE20142290A1 (hu)
PL (1) PL3326642T3 (hu)
SG (1) SG11201404836QA (hu)
WO (1) WO2013121416A1 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
MX362446B (es) * 2012-02-14 2019-01-18 Opko Biologics Ltd Factores de coagulacion de accion prolongada y metodos de produccion de los mismos.
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
EP3240564A4 (en) * 2014-12-10 2018-05-30 OPKO Biologics Ltd. Methods of producing long acting ctp-modified polypeptides
KR102662956B1 (ko) * 2015-06-19 2024-05-03 옵코 바이오로직스 리미티드 장기-작용성 응고 인자 및 그의 제조 방법
TWI741992B (zh) 2015-08-03 2021-10-11 美商百歐維拉提夫治療公司 因子ｉｘ融合蛋白以及其製備及使用方法
EA201990255A1 (ru) * 2016-07-11 2019-07-31 Опко Байолоджикс Лтд Фактор свертывания крови vii пролонгированного действия и способы его получения
WO2018032638A1 (zh) 2016-08-19 2018-02-22 安源医药科技（上海）有限公司 用于构建融合蛋白的连接肽
CN107759696A (zh) 2016-08-19 2018-03-06 安源医药科技（上海）有限公司 人白介素7融合蛋白及其制备方法
CN106279437B (zh) 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
JP7023925B2 (ja) 2017-03-08 2022-02-22 テイ・エス テック株式会社 乗物用シート
US11981718B2 (en) 2020-05-27 2024-05-14 Ampsource Biopharma Shanghai Inc. Dual-function protein for lipid and blood glucose regulation

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MX362446B (es) * 2012-02-14 2019-01-18 Opko Biologics Ltd Factores de coagulacion de accion prolongada y metodos de produccion de los mismos.
SG10202010383YA (en) * 2012-11-20 2020-11-27 Opko Biologics Ltd Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides

Also Published As

Publication number Publication date
KR102310704B1 (ko) 2021-10-08
MX2022008807A (es) 2022-08-11
DK3326642T3 (da) 2021-02-22
EA028578B1 (ru) 2017-12-29
MX2019000708A (es) 2020-09-02
EP3326642B1 (en) 2020-11-25
JP2015508771A (ja) 2015-03-23
PE20142290A1 (es) 2015-01-15
NO2920022T3 (hu) 2018-06-09
ES2665319T3 (es) 2018-04-25
AU2017219044A1 (en) 2017-09-14
KR102630953B1 (ko) 2024-01-29
PL3326642T3 (pl) 2021-06-14
EP2822576B1 (en) 2018-01-10
AU2017219044B2 (en) 2019-05-30
CO7131365A2 (es) 2014-12-01
EA201790960A3 (ru) 2018-01-31
MY172539A (en) 2019-11-30
ES2855133T3 (es) 2021-09-23
IL282121A (en) 2021-05-31
EA201790960A2 (ru) 2017-09-29
KR102118729B1 (ko) 2020-06-05
JP6242819B2 (ja) 2017-12-06
KR20210125595A (ko) 2021-10-18
WO2013121416A1 (en) 2013-08-22
JP6510002B2 (ja) 2019-05-08
CL2017002233A1 (es) 2018-05-11
AU2016202829A1 (en) 2016-05-19
AU2013219935A1 (en) 2014-09-25
KR20140134673A (ko) 2014-11-24
IL282121B (en) 2022-06-01
EP3326642A1 (en) 2018-05-30
EP2822576A1 (en) 2015-01-14
AU2016202829B2 (en) 2017-05-25
CA2870621A1 (en) 2013-08-22
HK1205460A1 (en) 2015-12-18
DK2822576T3 (en) 2018-04-16
EP3791890A1 (en) 2021-03-17
CN109535245A (zh) 2019-03-29
MX2014009910A (es) 2015-09-28
SG11201404836QA (en) 2014-12-30
CA2870621C (en) 2022-08-09
BR112014020198A2 (pt) 2018-05-15
AU2013219935B2 (en) 2016-02-04
IL264959B (en) 2021-08-31
CN104427994A (zh) 2015-03-18
BR122021004014B1 (pt) 2022-12-27
KR20200063274A (ko) 2020-06-04
EP2822576A4 (en) 2015-11-25
MX362446B (es) 2019-01-18
JP2018065815A (ja) 2018-04-26
EA201491519A1 (ru) 2014-12-30
CL2014002183A1 (es) 2015-01-09

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