DK258975A - Fremgangsmade til fremstilling af benzimidazoler - Google Patents

Fremgangsmade til fremstilling af benzimidazoler

Info

Publication number
DK258975A
DK258975A DK258975A DK258975A DK258975A DK 258975 A DK258975 A DK 258975A DK 258975 A DK258975 A DK 258975A DK 258975 A DK258975 A DK 258975A DK 258975 A DK258975 A DK 258975A
Authority
DK
Denmark
Prior art keywords
benzimidazoles
procedure
production
Prior art date
Application number
DK258975A
Other languages
Danish (da)
English (en)
Inventor
V Austel
E Kutter
J Heider
W Eberlein
R Kadatz
W Diederen
Original Assignee
Thomae Ges Mit Beschrenkter Ha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742427943 external-priority patent/DE2427943C2/de
Application filed by Thomae Ges Mit Beschrenkter Ha filed Critical Thomae Ges Mit Beschrenkter Ha
Publication of DK258975A publication Critical patent/DK258975A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK258975A 1974-06-10 1975-06-09 Fremgangsmade til fremstilling af benzimidazoler DK258975A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742427943 DE2427943C2 (de) 1974-06-10 1974-06-10 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2516040A DE2516040C2 (de) 1974-06-10 1975-04-12 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
DK258975A true DK258975A (da) 1975-12-11

Family

ID=25767253

Family Applications (1)

Application Number Title Priority Date Filing Date
DK258975A DK258975A (da) 1974-06-10 1975-06-09 Fremgangsmade til fremstilling af benzimidazoler

Country Status (23)

Country Link
US (1) US4026891A (it)
JP (1) JPS6015632B2 (it)
AT (1) AT342610B (it)
BE (1) BE830030A (it)
BG (2) BG23216A3 (it)
CA (1) CA1041095A (it)
CH (1) CH620438A5 (it)
CS (1) CS195292B2 (it)
DD (1) DD120440A5 (it)
DE (1) DE2516040C2 (it)
DK (1) DK258975A (it)
ES (2) ES437296A1 (it)
FI (1) FI59408C (it)
FR (1) FR2273545A1 (it)
GB (1) GB1466547A (it)
HU (1) HU171059B (it)
IE (1) IE41257B1 (it)
IL (1) IL47445A (it)
NL (1) NL178969C (it)
NO (1) NO142402C (it)
PH (1) PH14298A (it)
RO (1) RO68750A (it)
SE (1) SE420836B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152496B (da) * 1978-08-25 1988-03-07 Thomae Gmbh Dr K Analogifremgangsmaade til fremstilling af i 5- eller 6-stilling med en pyridazinonring substituerede benzimidazoler eller deres fysiologisk acceptable syreadditionssalte

Families Citing this family (41)

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JPS53117215A (en) * 1977-03-24 1978-10-13 Hideyoshi Morita Earthquakeeproof steel beam
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3006671A1 (de) * 1980-02-22 1981-08-27 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel
US4699909A (en) * 1981-07-25 1987-10-13 Dr. Karl Thomae Gmbh Benzotriazolyl-4,5-dihydro-3(2H)-pyridazinones
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
US4840955A (en) * 1984-12-24 1989-06-20 Warner-Lambert Company 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
US4868300A (en) * 1985-11-22 1989-09-19 Rorer Pharmaceutical Corporation Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
US4785101A (en) * 1985-11-22 1988-11-15 Rorer Pharmaceutical Corporation Benzodiazinone-hydroxypyrazolyl compounds, cardiotonic compositions including the same and their uses
US4725686A (en) * 1985-11-22 1988-02-16 William H. Rorer, Inc. Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
JPS62249018A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
JPS62249019A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
US5002944A (en) * 1986-10-29 1991-03-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cardiotonic activity
US4859672A (en) * 1986-10-29 1989-08-22 Rorer Pharmaceutical Corporation Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone
JPS63181827U (it) * 1987-05-13 1988-11-24
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
US6465484B1 (en) 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
DE69823240T2 (de) * 1998-10-23 2005-04-28 Toray Industries, Inc. Immunmodulierende arzneimittelzusammenstellung
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
AR051294A1 (es) * 2004-09-20 2007-01-03 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
WO2006034341A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
US7592343B2 (en) * 2004-09-20 2009-09-22 Xenon Pharmaceuticals Inc. Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors
BRPI0515488A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados de heterocìclicos e seu uso como agentes terapêuticos
EP1799668A1 (en) 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
US8071603B2 (en) * 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
CA2580787A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
JP4958786B2 (ja) 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
JP4714921B2 (ja) * 2005-02-14 2011-07-06 トーアエイヨー株式会社 ピモベンダンの製造法及びその中間体
BRPI0611187A2 (pt) * 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
EP2233470B1 (en) * 2005-07-04 2011-12-07 High Point Pharmaceuticals, LLC Histamine H3 receptor antagonists
CN101282929A (zh) 2005-08-15 2008-10-08 Irm责任有限公司 用作tpo模拟物的化合物和组合物
SG163547A1 (en) * 2006-05-29 2010-08-30 High Point Pharmaceuticals Llc 3- (1, 3-benz0di0x0l-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist
EP2014656A3 (en) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC New heteocyclic h3 antagonists
AR075858A1 (es) 2009-03-18 2011-05-04 Schering Corp Compuestos biciclicos como inhibidores de diacilglicerol aciltransferasa
US8729263B2 (en) 2012-08-13 2014-05-20 Novartis Ag 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
CN105636953B (zh) * 2013-07-31 2018-01-02 诺华股份有限公司 1,4‑二取代的哒嗪衍生物及其用于治疗与smn缺乏相关的病症的用途
WO2018086703A1 (en) * 2016-11-11 2018-05-17 Bayer Pharma Aktiengesellschaft Dihydropyridazinones substituted with phenylureas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US3705157A (en) * 1970-10-19 1972-12-05 American Cyanamid Co Azolylpyridazine compounds and quaternary salts thereof
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152496B (da) * 1978-08-25 1988-03-07 Thomae Gmbh Dr K Analogifremgangsmaade til fremstilling af i 5- eller 6-stilling med en pyridazinonring substituerede benzimidazoler eller deres fysiologisk acceptable syreadditionssalte

Also Published As

Publication number Publication date
IL47445A0 (en) 1975-08-31
DD120440A5 (it) 1976-06-12
ES437296A1 (es) 1977-01-01
FI59408B (fi) 1981-04-30
PH14298A (en) 1981-05-19
FI59408C (fi) 1981-08-10
SE7506583L (sv) 1975-12-11
HU171059B (hu) 1977-10-28
FR2273545A1 (fr) 1976-01-02
CS195292B2 (en) 1980-01-31
JPS516980A (it) 1976-01-20
AT342610B (de) 1978-04-10
ES441340A1 (es) 1977-03-16
IE41257L (en) 1975-12-10
CA1041095A (en) 1978-10-24
DE2516040A1 (de) 1976-11-04
JPS6015632B2 (ja) 1985-04-20
NO142402C (no) 1980-08-13
CH620438A5 (it) 1980-11-28
BE830030A (fr) 1975-12-09
NO142402B (no) 1980-05-05
NL7506806A (nl) 1975-12-12
FR2273545B1 (it) 1979-08-10
NL178969C (nl) 1986-06-16
DE2516040C2 (de) 1984-12-20
BG24052A3 (en) 1977-12-15
BG23216A3 (bg) 1977-07-12
AU8192675A (en) 1976-12-16
RO68750A (ro) 1980-03-15
ATA344575A (de) 1977-08-15
NO752022L (it) 1975-12-11
FI751700A (it) 1975-12-11
IL47445A (en) 1978-07-31
IE41257B1 (en) 1979-11-21
SE420836B (sv) 1981-11-02
US4026891A (en) 1977-05-31
GB1466547A (en) 1977-03-09

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Legal Events

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AHS Application shelved for other reasons than non-payment