ATA344575A - Verfahren zur herstellung neuer pyridazinderivate und deren saureadditionssalze - Google Patents

Verfahren zur herstellung neuer pyridazinderivate und deren saureadditionssalze

Info

Publication number
ATA344575A
ATA344575A AT753445A AT344575A ATA344575A AT A344575 A ATA344575 A AT A344575A AT 753445 A AT753445 A AT 753445A AT 344575 A AT344575 A AT 344575A AT A344575 A ATA344575 A AT A344575A
Authority
AT
Austria
Prior art keywords
preparation
pyridazine derivatives
additional salts
acid additional
new pyridazine
Prior art date
Application number
AT753445A
Other languages
English (en)
Other versions
AT342610B (de
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742427943 external-priority patent/DE2427943C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ATA344575A publication Critical patent/ATA344575A/de
Application granted granted Critical
Publication of AT342610B publication Critical patent/AT342610B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
AT344575A 1974-06-10 1975-05-06 Verfahren zur herstellung neuer pyridazinderivate und deren saureadditionssalze AT342610B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742427943 DE2427943C2 (de) 1974-06-10 1974-06-10 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2516040A DE2516040C2 (de) 1974-06-10 1975-04-12 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
ATA344575A true ATA344575A (de) 1977-08-15
AT342610B AT342610B (de) 1978-04-10

Family

ID=25767253

Family Applications (1)

Application Number Title Priority Date Filing Date
AT344575A AT342610B (de) 1974-06-10 1975-05-06 Verfahren zur herstellung neuer pyridazinderivate und deren saureadditionssalze

Country Status (23)

Country Link
US (1) US4026891A (de)
JP (1) JPS6015632B2 (de)
AT (1) AT342610B (de)
BE (1) BE830030A (de)
BG (2) BG23216A3 (de)
CA (1) CA1041095A (de)
CH (1) CH620438A5 (de)
CS (1) CS195292B2 (de)
DD (1) DD120440A5 (de)
DE (1) DE2516040C2 (de)
DK (1) DK258975A (de)
ES (2) ES437296A1 (de)
FI (1) FI59408C (de)
FR (1) FR2273545A1 (de)
GB (1) GB1466547A (de)
HU (1) HU171059B (de)
IE (1) IE41257B1 (de)
IL (1) IL47445A (de)
NL (1) NL178969C (de)
NO (1) NO142402C (de)
PH (1) PH14298A (de)
RO (1) RO68750A (de)
SE (1) SE420836B (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53117215A (en) * 1977-03-24 1978-10-13 Hideyoshi Morita Earthquakeeproof steel beam
ES8101067A1 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3006671A1 (de) * 1980-02-22 1981-08-27 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
US4699909A (en) * 1981-07-25 1987-10-13 Dr. Karl Thomae Gmbh Benzotriazolyl-4,5-dihydro-3(2H)-pyridazinones
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
US4840955A (en) * 1984-12-24 1989-06-20 Warner-Lambert Company 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents
US4725686A (en) * 1985-11-22 1988-02-16 William H. Rorer, Inc. Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4785101A (en) * 1985-11-22 1988-11-15 Rorer Pharmaceutical Corporation Benzodiazinone-hydroxypyrazolyl compounds, cardiotonic compositions including the same and their uses
US4868300A (en) * 1985-11-22 1989-09-19 Rorer Pharmaceutical Corporation Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
JPS62249018A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
JPS62249019A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
US5002944A (en) * 1986-10-29 1991-03-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cardiotonic activity
US4859672A (en) * 1986-10-29 1989-08-22 Rorer Pharmaceutical Corporation Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone
JPS63181827U (de) * 1987-05-13 1988-11-24
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
US6465484B1 (en) 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
ATE264104T1 (de) * 1998-10-23 2004-04-15 Toray Industries Immunmodulierende arzneimittelzusammenstellung
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
CA2580787A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
BRPI0515477A (pt) * 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos bicìclicos e o uso dos mesmos como inibidores de estaroil-coa-desaturase (scd)
BRPI0515488A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados de heterocìclicos e seu uso como agentes terapêuticos
US7592343B2 (en) * 2004-09-20 2009-09-22 Xenon Pharmaceuticals Inc. Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors
AR051202A1 (es) * 2004-09-20 2006-12-27 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
JP5094398B2 (ja) 2004-09-20 2012-12-12 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環式誘導体およびステアロイル−CoAデサチュラーゼのメディエータとしてのそれらの使用
TW200626155A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
EP2266569A3 (de) 2004-09-20 2011-03-09 Xenon Pharmaceuticals Inc. Heterozyklische Derivate und ihre Verwendung als Stearoyl-Coa-Desaturase-Inhibitoren
JP4714921B2 (ja) * 2005-02-14 2011-07-06 トーアエイヨー株式会社 ピモベンダンの製造法及びその中間体
EP2540296A1 (de) * 2005-06-03 2013-01-02 Xenon Pharmaceuticals Inc. Arminothiazolderivate als menschliche Stearoyl-Coa-Desaturase-Hemmer
BRPI0613564A2 (pt) 2005-07-04 2011-01-18 Novo Nordisk As compostos, seus usos na preparação de composições farmacêuticas e composições farmacêuticas compreendendo os mesmos
CN101282929A (zh) * 2005-08-15 2008-10-08 Irm责任有限公司 用作tpo模拟物的化合物和组合物
CN102295606A (zh) * 2006-05-29 2011-12-28 高点制药有限责任公司 合成3-(1,3-苯并间二氧杂环戊烯-5-基)-6-(4-环丙基哌嗪-1-基)-哒嗪的方法及其适用的中间体
EP2014656A3 (de) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC Neue heterocyclische H3-Antagonisten
US20120022057A1 (en) 2009-03-18 2012-01-26 Schering Corporation Bicyclic compounds as inhibitors of diacyglycerol acyltransferase
MY174339A (en) 2012-08-13 2020-04-09 Novartis Ag 1,4-disubstituted pyridazine analogs and methods for treating smn-deficiency-related conditions
CA2918805C (en) * 2013-07-31 2023-02-28 Novartis Ag 1,4-disubstituted pyridazine derivatives and their use for treating smn-deficiency-related conditions
WO2018086703A1 (en) * 2016-11-11 2018-05-17 Bayer Pharma Aktiengesellschaft Dihydropyridazinones substituted with phenylureas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US3705157A (en) * 1970-10-19 1972-12-05 American Cyanamid Co Azolylpyridazine compounds and quaternary salts thereof
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Also Published As

Publication number Publication date
PH14298A (en) 1981-05-19
AU8192675A (en) 1976-12-16
CH620438A5 (de) 1980-11-28
JPS516980A (de) 1976-01-20
FI59408B (fi) 1981-04-30
BG24052A3 (en) 1977-12-15
CS195292B2 (en) 1980-01-31
NL178969C (nl) 1986-06-16
NL7506806A (nl) 1975-12-12
JPS6015632B2 (ja) 1985-04-20
IE41257L (en) 1975-12-10
DD120440A5 (de) 1976-06-12
NO142402B (no) 1980-05-05
US4026891A (en) 1977-05-31
IL47445A (en) 1978-07-31
ES441340A1 (es) 1977-03-16
IL47445A0 (en) 1975-08-31
FR2273545B1 (de) 1979-08-10
RO68750A (ro) 1980-03-15
DK258975A (da) 1975-12-11
BG23216A3 (de) 1977-07-12
NO142402C (no) 1980-08-13
SE7506583L (sv) 1975-12-11
GB1466547A (en) 1977-03-09
FI751700A (de) 1975-12-11
IE41257B1 (en) 1979-11-21
NO752022L (de) 1975-12-11
CA1041095A (en) 1978-10-24
HU171059B (hu) 1977-10-28
DE2516040C2 (de) 1984-12-20
DE2516040A1 (de) 1976-11-04
SE420836B (sv) 1981-11-02
BE830030A (fr) 1975-12-09
FR2273545A1 (fr) 1976-01-02
AT342610B (de) 1978-04-10
ES437296A1 (es) 1977-01-01
FI59408C (fi) 1981-08-10

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee