IL47445A - Pyridazinyl benzimidazoles, their preparation and pharmaceutical compositions containing them - Google Patents

Pyridazinyl benzimidazoles, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL47445A
IL47445A IL47445A IL4744575A IL47445A IL 47445 A IL47445 A IL 47445A IL 47445 A IL47445 A IL 47445A IL 4744575 A IL4744575 A IL 4744575A IL 47445 A IL47445 A IL 47445A
Authority
IL
Israel
Prior art keywords
benzimidazoles
pyridazinyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL47445A
Other languages
English (en)
Other versions
IL47445A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742427943 external-priority patent/DE2427943C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL47445A0 publication Critical patent/IL47445A0/xx
Publication of IL47445A publication Critical patent/IL47445A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
IL47445A 1974-06-10 1975-06-09 Pyridazinyl benzimidazoles, their preparation and pharmaceutical compositions containing them IL47445A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742427943 DE2427943C2 (de) 1974-06-10 1974-06-10 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2516040A DE2516040C2 (de) 1974-06-10 1975-04-12 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
IL47445A0 IL47445A0 (en) 1975-08-31
IL47445A true IL47445A (en) 1978-07-31

Family

ID=25767253

Family Applications (1)

Application Number Title Priority Date Filing Date
IL47445A IL47445A (en) 1974-06-10 1975-06-09 Pyridazinyl benzimidazoles, their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US4026891A (de)
JP (1) JPS6015632B2 (de)
AT (1) AT342610B (de)
BE (1) BE830030A (de)
BG (2) BG23216A3 (de)
CA (1) CA1041095A (de)
CH (1) CH620438A5 (de)
CS (1) CS195292B2 (de)
DD (1) DD120440A5 (de)
DE (1) DE2516040C2 (de)
DK (1) DK258975A (de)
ES (2) ES437296A1 (de)
FI (1) FI59408C (de)
FR (1) FR2273545A1 (de)
GB (1) GB1466547A (de)
HU (1) HU171059B (de)
IE (1) IE41257B1 (de)
IL (1) IL47445A (de)
NL (1) NL178969C (de)
NO (1) NO142402C (de)
PH (1) PH14298A (de)
RO (1) RO68750A (de)
SE (1) SE420836B (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53117215A (en) * 1977-03-24 1978-10-13 Hideyoshi Morita Earthquakeeproof steel beam
ES482789A0 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3006671A1 (de) * 1980-02-22 1981-08-27 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
US4699909A (en) * 1981-07-25 1987-10-13 Dr. Karl Thomae Gmbh Benzotriazolyl-4,5-dihydro-3(2H)-pyridazinones
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
US4840955A (en) * 1984-12-24 1989-06-20 Warner-Lambert Company 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents
US4785101A (en) * 1985-11-22 1988-11-15 Rorer Pharmaceutical Corporation Benzodiazinone-hydroxypyrazolyl compounds, cardiotonic compositions including the same and their uses
US4725686A (en) * 1985-11-22 1988-02-16 William H. Rorer, Inc. Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
US4868300A (en) * 1985-11-22 1989-09-19 Rorer Pharmaceutical Corporation Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
JPS62249019A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
JPS62249018A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
US4859672A (en) * 1986-10-29 1989-08-22 Rorer Pharmaceutical Corporation Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone
US5002944A (en) * 1986-10-29 1991-03-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cardiotonic activity
JPS63181827U (de) * 1987-05-13 1988-11-24
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
US6465484B1 (en) 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
CN1148190C (zh) * 1998-10-23 2004-05-05 东丽株式会社 用于免疫调节的药物组合物
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
EP1804799B1 (de) * 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterozyklische Derivate und ihre Verwendung als Stearoyl-Coa-Desaturase-Inhibitoren
CA2580781A1 (en) * 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Bicyclic heterocyclic derivatives and their use as inhibitors of stearoyl-coa-desaturase (scd)
AR051202A1 (es) * 2004-09-20 2006-12-27 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
AU2005286846A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
BRPI0515483A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos para o tratamento de doenças mediadas por enzimas estearoil-coa desaturase
TW200626572A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
AR051094A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
BRPI0515505A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados heterocìclicos e sua utilização como inibidores da estearoil-coa desaturase
JP4714921B2 (ja) * 2005-02-14 2011-07-06 トーアエイヨー株式会社 ピモベンダンの製造法及びその中間体
EP2540296A1 (de) * 2005-06-03 2013-01-02 Xenon Pharmaceuticals Inc. Arminothiazolderivate als menschliche Stearoyl-Coa-Desaturase-Hemmer
WO2007003604A2 (en) 2005-07-04 2007-01-11 Novo Nordisk A/S Hists1mine h3 receptor antagonists
JP5175730B2 (ja) * 2005-08-15 2013-04-03 アイアールエム・リミテッド・ライアビリティ・カンパニー Ｔｐｏ模倣剤としての化合物および組成物
PL2079732T3 (pl) * 2006-05-29 2012-05-31 High Point Pharmaceuticals Llc 3-(1,3-benzodioksol-5-ylo)-6-(4-cyklopropylopiperazyn-1-ylo)-pirydazyna, jej sole i solwaty oraz jej zastosowanie jako antagonisty receptora histaminowego h3
EP2014656A3 (de) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC Neue heterocyclische H3-Antagonisten
CA2755251A1 (en) 2009-03-18 2010-09-23 Schering Corporation Bicyclic compounds as inhibitors of diacylglycerol acyltransferase
MY174339A (en) 2012-08-13 2020-04-09 Novartis Ag 1,4-disubstituted pyridazine analogs and methods for treating smn-deficiency-related conditions
KR102318727B1 (ko) * 2013-07-31 2021-10-28 노파르티스 아게 1,4-이치환된 피리다진 유사체 및 smn-결핍-관련 상태를 치료하기 위한 그의 용도
WO2018086703A1 (en) * 2016-11-11 2018-05-17 Bayer Pharma Aktiengesellschaft Dihydropyridazinones substituted with phenylureas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US3705157A (en) * 1970-10-19 1972-12-05 American Cyanamid Co Azolylpyridazine compounds and quaternary salts thereof
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Also Published As

Publication number Publication date
AT342610B (de) 1978-04-10
BG24052A3 (en) 1977-12-15
IL47445A0 (en) 1975-08-31
BG23216A3 (de) 1977-07-12
DK258975A (da) 1975-12-11
DD120440A5 (de) 1976-06-12
CA1041095A (en) 1978-10-24
US4026891A (en) 1977-05-31
NO142402B (no) 1980-05-05
JPS6015632B2 (ja) 1985-04-20
FR2273545B1 (de) 1979-08-10
FR2273545A1 (fr) 1976-01-02
SE420836B (sv) 1981-11-02
IE41257B1 (en) 1979-11-21
CS195292B2 (en) 1980-01-31
BE830030A (fr) 1975-12-09
AU8192675A (en) 1976-12-16
CH620438A5 (de) 1980-11-28
ES437296A1 (es) 1977-01-01
FI59408C (fi) 1981-08-10
SE7506583L (sv) 1975-12-11
FI59408B (fi) 1981-04-30
NL178969C (nl) 1986-06-16
IE41257L (en) 1975-12-10
NO142402C (no) 1980-08-13
HU171059B (hu) 1977-10-28
DE2516040C2 (de) 1984-12-20
NL7506806A (nl) 1975-12-12
ATA344575A (de) 1977-08-15
FI751700A (de) 1975-12-11
RO68750A (ro) 1980-03-15
JPS516980A (de) 1976-01-20
GB1466547A (en) 1977-03-09
PH14298A (en) 1981-05-19
DE2516040A1 (de) 1976-11-04
NO752022L (de) 1975-12-11
ES441340A1 (es) 1977-03-16

Similar Documents

Publication Publication Date Title
IL47445A (en) Pyridazinyl benzimidazoles, their preparation and pharmaceutical compositions containing them
IL46967A (en) N-pyrrolidyl-, n-piperidyl-,n-pyridyl-and n-pyrroly-polyfluoroalkyl-benzamide derivatives, their preparation and pharmaceutical compositions comprising them
IL47046A (en) Acylaniline derivatives,their preparation and fungicidal compositions containing them
IL47625A (en) 4-heterocyclyl-6,7-dialkoxyquin-azoline derivatives and pharmaceutical compositions containing them
IL48592A (en) 1-substituted-4-benzypiperidine derivatives,their preparation and pharmaceutical composistions comprising them
IL48593A (en) 1-substituted-4-benzylidenepiperidine derivatives, their preparation and pharmaceutical compositions comprising them
IL46695A (en) Substituted n-(1-benzylpyrrolidinyl-2-alkyl)-benzamides, their preparation and pharmaceutical compositions containing them
IL47529A0 (en) New benzimidazolinone derivatives,their preparation and pharmaceutical compositions containing them
IL46966A0 (en) 1,1-diaryl-1-oxadiazolyl-alkylamines,their preparation and pharmaceutical compositions containing them
IL48069A0 (en) New diazepine derivatives,their preparation and pharmaceutical compositions containing them
IL48061A (en) 4a-phenyl-cis-decahydroisoquinoline derivatives, their preparation and pharmaceutical compositions containing them
IL48502A0 (en) Novel benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL47329A0 (en) New pyridobenzodiazepinones,their preparation and pharmaceutical compositions containing them
IL47404A0 (en) Pyrazolobenzazepines,their manufacture and pharmaceutical compositions containing them
IL47196A (en) 7-substituted-8-aminomethyl-isoflavone derivatives, their preparation and pharmaceutical compositions containing them
HK20881A (en) Cinnamamides,their preparation and pharmaceutical compositions containing them
IL46476A0 (en) 2-substituted 4,5-diphenylthiazoles,their preparation and pharmaceutical compositions containing them
IL47195A0 (en) New 5-substituted phenyltetrazoles,their preparation and pharmaceutical compositions containing them
IL48441A0 (en) Isoindole derivatives,their manufacture and pharmaceutical compositions containing them
IL48463A (en) 2-acyl-hydrazono-formyl-quinoxaline-1,4-dioxides, their preparation and pharmaceutical compositions containing them
IL49099A (en) Xanthene-9-carboxylates, their preparation and pharmaceutical compositions containing them
IL48526A0 (en) Diaryloxy-imidazolyl-o,n-acetals,their preparation and pharmaceutical compositions containing them
IL47522A0 (en) Ergopeptine derivatives,their preparation and pharmaceutical compositions containing them
NZ179530A (en) 9-aminoalk(en)yl-9,10-dihydro9,10-methanoanthracenes and pharmaceutical compositions
IL46409A (en) 7,8-dihalo-1,2,3,4-tetrahydro-isoquinolines their preparation and pharmaceutical compositions containing them