BG24052A3 - Метод за получаване на бензимидазоли - Google Patents

Метод за получаване на бензимидазоли

Info

Publication number
BG24052A3
BG24052A3 BG030103A BG3010375A BG24052A3 BG 24052 A3 BG24052 A3 BG 24052A3 BG 030103 A BG030103 A BG 030103A BG 3010375 A BG3010375 A BG 3010375A BG 24052 A3 BG24052 A3 BG 24052A3
Authority
BG
Bulgaria
Prior art keywords
benzimidazoles
preparing
preparing benzimidazoles
Prior art date
Application number
BG030103A
Other languages
English (en)
Inventor
Volkhard Austel
Eberhard Kutter
Joachim Heider
Wolfgang Eberlein
Rudolf Kadatz
Willi Diederen
Original Assignee
Dr. Karl Thomae Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742427943 external-priority patent/DE2427943C2/de
Application filed by Dr. Karl Thomae Gmbh filed Critical Dr. Karl Thomae Gmbh
Publication of BG24052A3 publication Critical patent/BG24052A3/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG030103A 1974-06-10 1975-05-27 Метод за получаване на бензимидазоли BG24052A3 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742427943 DE2427943C2 (de) 1974-06-10 1974-06-10 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2516040A DE2516040C2 (de) 1974-06-10 1975-04-12 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BG24052A3 true BG24052A3 (bg) 1977-12-15

Family

ID=25767253

Family Applications (2)

Application Number Title Priority Date Filing Date
BG030846A BG23216A3 (bg) 1974-06-10 1975-05-27 Метод за получаване на бензимидазоли
BG030103A BG24052A3 (bg) 1974-06-10 1975-05-27 Метод за получаване на бензимидазоли

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BG030846A BG23216A3 (bg) 1974-06-10 1975-05-27 Метод за получаване на бензимидазоли

Country Status (23)

Country Link
US (1) US4026891A (bg)
JP (1) JPS6015632B2 (bg)
AT (1) AT342610B (bg)
BE (1) BE830030A (bg)
BG (2) BG23216A3 (bg)
CA (1) CA1041095A (bg)
CH (1) CH620438A5 (bg)
CS (1) CS195292B2 (bg)
DD (1) DD120440A5 (bg)
DE (1) DE2516040C2 (bg)
DK (1) DK258975A (bg)
ES (2) ES437296A1 (bg)
FI (1) FI59408C (bg)
FR (1) FR2273545A1 (bg)
GB (1) GB1466547A (bg)
HU (1) HU171059B (bg)
IE (1) IE41257B1 (bg)
IL (1) IL47445A (bg)
NL (1) NL178969C (bg)
NO (1) NO142402C (bg)
PH (1) PH14298A (bg)
RO (1) RO68750A (bg)
SE (1) SE420836B (bg)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53117215A (en) * 1977-03-24 1978-10-13 Hideyoshi Morita Earthquakeeproof steel beam
ES8101067A1 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3006671A1 (de) * 1980-02-22 1981-08-27 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
US4699909A (en) * 1981-07-25 1987-10-13 Dr. Karl Thomae Gmbh Benzotriazolyl-4,5-dihydro-3(2H)-pyridazinones
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
US4840955A (en) * 1984-12-24 1989-06-20 Warner-Lambert Company 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents
US4785101A (en) * 1985-11-22 1988-11-15 Rorer Pharmaceutical Corporation Benzodiazinone-hydroxypyrazolyl compounds, cardiotonic compositions including the same and their uses
US4725686A (en) * 1985-11-22 1988-02-16 William H. Rorer, Inc. Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4868300A (en) * 1985-11-22 1989-09-19 Rorer Pharmaceutical Corporation Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
JPS62249019A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
JPS62249018A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
US4859672A (en) * 1986-10-29 1989-08-22 Rorer Pharmaceutical Corporation Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone
US5002944A (en) * 1986-10-29 1991-03-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cardiotonic activity
JPS63181827U (bg) * 1987-05-13 1988-11-24
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
US6465484B1 (en) 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
CA2347939C (en) * 1998-10-23 2006-10-10 Akira Matsumori Composition for the treatment of rheumatism, hepatitis or pancreatitis
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
JP5043668B2 (ja) 2004-09-20 2012-10-10 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
MX2007003332A (es) * 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de estearoil-coa-desaturasa.
TW200626154A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
EP1804799B1 (en) * 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
JP5080256B2 (ja) * 2004-09-20 2012-11-21 ゼノン・ファーマシューティカルズ・インコーポレイテッド 二環式複素環誘導体およびステアロイル−ＣｏＡデサチュラーゼ（ＳＣＤ）のインヒビターとしてのそれらの使用
MX2007003327A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos, y su uso como mediadores de estearoil-coa desaturasa.
BRPI0515483A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos para o tratamento de doenças mediadas por enzimas estearoil-coa desaturase
JP5149009B2 (ja) 2004-09-20 2013-02-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド ヒトステアロイル−ＣｏＡデサチュラーゼを阻害するためのピリダジン誘導体
JP4714921B2 (ja) * 2005-02-14 2011-07-06 トーアエイヨー株式会社 ピモベンダンの製造法及びその中間体
MX2007015216A (es) * 2005-06-03 2008-02-22 Xenon Pharmaceuticals Inc Derivados de aminotiazol y sus usos como agentes terapeuticos.
MX2007015675A (es) 2005-07-04 2008-02-20 Novo Nordisk As Antagonistas del receptor de histamina h3.
BRPI0616994A2 (pt) 2005-08-15 2011-07-05 Irm Llc compostos e composições como miméticos de tpo
CN101460487A (zh) * 2006-05-29 2009-06-17 高点制药有限责任公司 3-(1，3-苯并间二氧杂环戊烯- 5-基)-6-(4-环丙基哌嗪-1-基)-哒嗪、其盐和溶剂合物及其作为组胺h3受体拮抗剂的用途
EP2014656A3 (en) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC New heteocyclic h3 antagonists
JP2012520887A (ja) 2009-03-18 2012-09-10 シェーリング コーポレイション ジアシルグリセロールアシルトランスフェラーゼの阻害剤としての二環式化合物
US8729263B2 (en) 2012-08-13 2014-05-20 Novartis Ag 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
KR20210130843A (ko) 2013-07-31 2021-11-01 노파르티스 아게 1,4-이치환된 피리다진 유사체 및 smn-결핍-관련 상태를 치료하기 위한 그의 용도
WO2018086703A1 (en) * 2016-11-11 2018-05-17 Bayer Pharma Aktiengesellschaft Dihydropyridazinones substituted with phenylureas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US3705157A (en) * 1970-10-19 1972-12-05 American Cyanamid Co Azolylpyridazine compounds and quaternary salts thereof
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Also Published As

Publication number Publication date
IE41257B1 (en) 1979-11-21
GB1466547A (en) 1977-03-09
IL47445A (en) 1978-07-31
FI751700A (bg) 1975-12-11
AT342610B (de) 1978-04-10
PH14298A (en) 1981-05-19
SE7506583L (sv) 1975-12-11
NO752022L (bg) 1975-12-11
IE41257L (en) 1975-12-10
AU8192675A (en) 1976-12-16
NO142402B (no) 1980-05-05
NO142402C (no) 1980-08-13
DE2516040A1 (de) 1976-11-04
CH620438A5 (bg) 1980-11-28
HU171059B (hu) 1977-10-28
FI59408B (fi) 1981-04-30
JPS516980A (bg) 1976-01-20
ES437296A1 (es) 1977-01-01
US4026891A (en) 1977-05-31
DD120440A5 (bg) 1976-06-12
RO68750A (ro) 1980-03-15
FI59408C (fi) 1981-08-10
JPS6015632B2 (ja) 1985-04-20
ES441340A1 (es) 1977-03-16
DE2516040C2 (de) 1984-12-20
SE420836B (sv) 1981-11-02
BG23216A3 (bg) 1977-07-12
IL47445A0 (en) 1975-08-31
BE830030A (fr) 1975-12-09
DK258975A (da) 1975-12-11
ATA344575A (de) 1977-08-15
NL178969C (nl) 1986-06-16
NL7506806A (nl) 1975-12-12
CA1041095A (en) 1978-10-24
CS195292B2 (en) 1980-01-31
FR2273545B1 (bg) 1979-08-10
FR2273545A1 (fr) 1976-01-02

Similar Documents

Publication Publication Date Title
BG24052A3 (bg) Метод за получаване на бензимидазоли
CS189680B2 (en) Method of preparing 3-aryloxy-3-phenylpropyl amines
CS194715B2 (en) Method of producing new derivatives of 2-/2-heterocyclylmethylthio/benzimidazole
JPS53101385A (en) Method of producing phenyllpyrimidine
BG27744A3 (bg) Метод за получаване на ханазолинови производни
CS188985B2 (en) Method of producing aryl-1-azolylmethanes
GR58521B (en) Preparation method of 2-descarboxy-2-(tetrazol-5-yl)-11-desoxy-15-substituted-omega-pentanoprostaglandins
BG24812A3 (bg) Метод за получаване на 8-тиометилерголини
BG24542A3 (bg) Метод за получаване на карбонилалдиминометанфосфонати
CS191882B2 (en) Method of preparing 7-methoxy-6-thia-tetracycline
CS193047B2 (en) Method of preparing macromoleculer adenine derivatives
BG23901A3 (bg) Метод за получаване на пиридобензодиазепинони
CS188938B2 (en) Method of producing xanthene-9-spiro-4-piperidines
SU677666A3 (en) Method of producing 7l-or extradiols
BG23900A3 (bg) Метод за получаване на 2-карбалкокси-амино- бензимидазолил-5(6)-сулфоновокисели фенилестери
CS189635B2 (en) Method of producing bromderivatives of 4-imido-thioazetidin-2-one
CS182298B2 (en) Method of producing substituted benzendisulphon-amides
JPS51125089A (en) Preparation method of piperazinopyrimidine derivatives
IL48565A0 (en) Method of preparation of 3-methylenecephams
CS191954B2 (en) Method of preparing 3-acetoxy-3,7-dimethyl-6-octennitrile
BG24403A3 (bg) Метод за получаване на 2-нитробензалдехид
JPS51125088A (en) Preparation method of new benzhydryloxyyalkylamine derivatives
SU576953A1 (en) Method of preparing tertiary phosphinoxides
CS188945B2 (en) Method of producing 1-aryluracils
BG24798A3 (bg) Метод за получаване на алфа-6-деокситетрациклин