NL7506806A - Werkwijze voor de bereiding van nieuwe benzimida- zolen. - Google Patents

Werkwijze voor de bereiding van nieuwe benzimida- zolen.

Info

Publication number
NL7506806A
NL7506806A NL7506806A NL7506806A NL7506806A NL 7506806 A NL7506806 A NL 7506806A NL 7506806 A NL7506806 A NL 7506806A NL 7506806 A NL7506806 A NL 7506806A NL 7506806 A NL7506806 A NL 7506806A
Authority
NL
Netherlands
Prior art keywords
benzimida
soles
preparation
new
new benzimida
Prior art date
Application number
NL7506806A
Other languages
English (en)
Other versions
NL178969C (nl
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742427943 external-priority patent/DE2427943C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NL7506806A publication Critical patent/NL7506806A/nl
Application granted granted Critical
Publication of NL178969C publication Critical patent/NL178969C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NLAANVRAGE7506806,A 1974-06-10 1975-06-09 Werkwijze voor de bereiding van een farmaceutisch preparaat met bloeddrukverlagende, antitrombotische en cardiotonische werking en daarvoor geschikte benzimidazolen. NL178969C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742427943 DE2427943C2 (de) 1974-06-10 1974-06-10 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2516040A DE2516040C2 (de) 1974-06-10 1975-04-12 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
NL7506806A true NL7506806A (nl) 1975-12-12
NL178969C NL178969C (nl) 1986-06-16

Family

ID=25767253

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7506806,A NL178969C (nl) 1974-06-10 1975-06-09 Werkwijze voor de bereiding van een farmaceutisch preparaat met bloeddrukverlagende, antitrombotische en cardiotonische werking en daarvoor geschikte benzimidazolen.

Country Status (23)

Country Link
US (1) US4026891A (nl)
JP (1) JPS6015632B2 (nl)
AT (1) AT342610B (nl)
BE (1) BE830030A (nl)
BG (2) BG23216A3 (nl)
CA (1) CA1041095A (nl)
CH (1) CH620438A5 (nl)
CS (1) CS195292B2 (nl)
DD (1) DD120440A5 (nl)
DE (1) DE2516040C2 (nl)
DK (1) DK258975A (nl)
ES (2) ES437296A1 (nl)
FI (1) FI59408C (nl)
FR (1) FR2273545A1 (nl)
GB (1) GB1466547A (nl)
HU (1) HU171059B (nl)
IE (1) IE41257B1 (nl)
IL (1) IL47445A (nl)
NL (1) NL178969C (nl)
NO (1) NO142402C (nl)
PH (1) PH14298A (nl)
RO (1) RO68750A (nl)
SE (1) SE420836B (nl)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53117215A (en) * 1977-03-24 1978-10-13 Hideyoshi Morita Earthquakeeproof steel beam
ES8101067A1 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3006671A1 (de) * 1980-02-22 1981-08-27 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
US4699909A (en) * 1981-07-25 1987-10-13 Dr. Karl Thomae Gmbh Benzotriazolyl-4,5-dihydro-3(2H)-pyridazinones
US4840955A (en) * 1984-12-24 1989-06-20 Warner-Lambert Company 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
US4725686A (en) * 1985-11-22 1988-02-16 William H. Rorer, Inc. Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4785101A (en) * 1985-11-22 1988-11-15 Rorer Pharmaceutical Corporation Benzodiazinone-hydroxypyrazolyl compounds, cardiotonic compositions including the same and their uses
US4868300A (en) * 1985-11-22 1989-09-19 Rorer Pharmaceutical Corporation Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
JPS62249018A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
JPS62249019A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
US5002944A (en) * 1986-10-29 1991-03-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cardiotonic activity
US4859672A (en) * 1986-10-29 1989-08-22 Rorer Pharmaceutical Corporation Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone
JPS63181827U (nl) * 1987-05-13 1988-11-24
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
US6465484B1 (en) 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
ATE264104T1 (de) * 1998-10-23 2004-04-15 Toray Industries Immunmodulierende arzneimittelzusammenstellung
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
BRPI0515478A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos e seu uso como mediadores de estearoil-coa-desaturase
CN101084207A (zh) * 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途
TW200626154A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
CN101083986A (zh) * 2004-09-20 2007-12-05 泽农医药公司 双环杂环衍生物及其作为硬脂酰CoA去饱和酶(SCD)抑制剂的用途
TW200626155A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
AU2005329423A1 (en) * 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
CN101083982A (zh) 2004-09-20 2007-12-05 泽农医药公司 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物
WO2006034279A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
JP4714921B2 (ja) * 2005-02-14 2011-07-06 トーアエイヨー株式会社 ピモベンダンの製造法及びその中間体
BRPI0611187A2 (pt) * 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
CA2614116A1 (en) * 2005-07-04 2007-01-11 Novo Nordisk A/S Novel medicaments
CA2618634A1 (en) 2005-08-15 2007-02-22 Irm Llc Compounds and compositions as tpo mimetics
CN102295606A (zh) * 2006-05-29 2011-12-28 高点制药有限责任公司 合成3-（1，3-苯并间二氧杂环戊烯-5-基）-6-（4-环丙基哌嗪-1-基）-哒嗪的方法及其适用的中间体
EP2014656A3 (en) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC New heteocyclic h3 antagonists
JP2012520887A (ja) * 2009-03-18 2012-09-10 シェーリング コーポレイション ジアシルグリセロールアシルトランスフェラーゼの阻害剤としての二環式化合物
US8729263B2 (en) 2012-08-13 2014-05-20 Novartis Ag 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
EA030631B1 (ru) * 2013-07-31 2018-09-28 Новартис Аг 1,4-дизамещенные аналоги пиридазинхинолина и способы лечения состояний, связанных с smn-дефицитом
WO2018086703A1 (en) * 2016-11-11 2018-05-17 Bayer Pharma Aktiengesellschaft Dihydropyridazinones substituted with phenylureas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US3705157A (en) * 1970-10-19 1972-12-05 American Cyanamid Co Azolylpyridazine compounds and quaternary salts thereof
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Also Published As

Publication number Publication date
PH14298A (en) 1981-05-19
SE7506583L (sv) 1975-12-11
CH620438A5 (nl) 1980-11-28
IL47445A0 (en) 1975-08-31
DD120440A5 (nl) 1976-06-12
IL47445A (en) 1978-07-31
AU8192675A (en) 1976-12-16
ES441340A1 (es) 1977-03-16
FI751700A (nl) 1975-12-11
ATA344575A (de) 1977-08-15
DK258975A (da) 1975-12-11
FI59408B (fi) 1981-04-30
US4026891A (en) 1977-05-31
JPS6015632B2 (ja) 1985-04-20
ES437296A1 (es) 1977-01-01
CS195292B2 (en) 1980-01-31
DE2516040C2 (de) 1984-12-20
IE41257B1 (en) 1979-11-21
RO68750A (ro) 1980-03-15
SE420836B (sv) 1981-11-02
CA1041095A (en) 1978-10-24
BG23216A3 (bg) 1977-07-12
FR2273545B1 (nl) 1979-08-10
DE2516040A1 (de) 1976-11-04
GB1466547A (en) 1977-03-09
AT342610B (de) 1978-04-10
NO142402C (no) 1980-08-13
FR2273545A1 (fr) 1976-01-02
IE41257L (en) 1975-12-10
BE830030A (fr) 1975-12-09
BG24052A3 (en) 1977-12-15
NO142402B (no) 1980-05-05
NO752022L (nl) 1975-12-11
JPS516980A (nl) 1976-01-20
FI59408C (fi) 1981-08-10
HU171059B (hu) 1977-10-28
NL178969C (nl) 1986-06-16

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee