DK2398889T3 - Fermenteringsbouillonformuleringer - Google Patents

Fermenteringsbouillonformuleringer Download PDF

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DK2398889T3
DK2398889T3 DK10705512.1T DK10705512T DK2398889T3 DK 2398889 T3 DK2398889 T3 DK 2398889T3 DK 10705512 T DK10705512 T DK 10705512T DK 2398889 T3 DK2398889 T3 DK 2398889T3
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acid
organic acid
cells
composition
weight
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Tom Tao Huang
Aaron Kelley
John Mclaughlin
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Danisco Us Inc
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/005—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor after treatment of microbial biomass not covered by C12N1/02 - C12N1/08
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Claims (20)

  1. EERMENTERINGSBOUILLONFORMULERINGER
    1. Fremgangsmåde til fremstilling af en fermenteringsbouillonformulering, hvilken fremgangsmåde omfatter følgende trin: (i) fremstilling af en første blanding, der omfatter: (a) tilvejebringelse af én eller flere fermenteringsbouilloner, (b) tilsætning af en første organisk syrebestanddel, der omfatter mindst én organisk syre med 1-5-kulstoffatomer og/eller et salt deraf i en mængde fra 0,1 til 15 vægt-% af blandingen, og (c) tilsætning af en anden organisk syrebestanddel, der omfatter mindst én organisk syre med 6- eller flere kulstofatomer og/eller et salt deraf i en mængde fra 0,025 til 5 vægt-% af blandingen, (ii) inkubation af den første blanding i et tidsrum og under betingelser, der resulterer i mindst et 4 log-fald i levedygtige celler i den ene eller flere fermenteringsbouilloner, hvorved fermenteringsbouillonformuleringen fremstilles; hvor den anden organiske syrebestanddel er benzoesyre, et salt af benzoesyre, cyclohexancarboxylsyre, et salt af cyclohexancarboxylsyre, 4-methylvalerianesyre, et salt af 4-methylvalerianesyre, phenyleddikesyre, et salt af phenyleddikesyre eller en blanding af to eller flere af ovenstående.
  2. 2. Fremgangsmåde ifølge krav 1, eller sammensætning ifølge krav 15, hvor den første organiske syrebestanddel er i en mængde fra 0,2 til 1 %, fra 0,2 % til 0,5%, fra 0,1 % til 10 %, fra 0,25 % til 5 % eller fra 0,3 % til 3 vægt-% af den første blanding, og/eller den anden organiske syrebestanddel er i en mængde fra 0,04 % til 3 %, fra 0,2 % til 0,5 %, fra 0,1 % til 1 %, fra 0,25 % til 5 % eller fra 0,3 % til 3 vægt-% af den første blanding eller sammensætning,
  3. 3. Fremgangsmåde ifølge et hvilket som helst af kravene 1 eller 2, hvor tidsrummet er fra 8 timer til 36 timer, såsom fra 20 timer til 28 timer.
  4. 4. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 3, hvor betingelserne indbefatter en temperatur på 20 °C til 50 °C, såsom 25 °C til 40 °C, for eksempel 28 °C til 33 °C.
  5. 5. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 4, hvor betingelserne indbefatter et pH på 3,5 til 5, såsom et pH på 4 til 4,7, for eksempel et pH på 4,2 til 4,5.
  6. 6. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 5, hvor cellerne er svampeceller, for eksempel filamentøse svampeceller, såsom celler fra arterne Trichoderma, Aspergillus, Penicillium, Humicola, Chrysosporium eller Neurospora.
  7. 7. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 6, eller sammensætning ifølge et hvilket som helst af kravene 15 til 18, hvor den første organiske syrebestanddel omfatter eller består af eddikesyre, et salt af eddikesyre, myresyre, et salt af myresyre, propionsyre, et salt af propionsyre eller en blanding af to eller flere af ovenstående.
  8. 8. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 7, eller sammensætning ifølge et hvilket som helst af kravene 15 til 17, hvor den første organiske syrebestanddel omfatter et natrium-, kalium-, calcium- eller magnesiumsalt af den organiske syre med 1-5 kulstofatomer, og/eller hvor den anden organiske syrebestanddel omfatter et natrium-, kalium-, calcium- eller magnesiumsalt af den organiske syre med 6 eller flere kulstofatomer.
  9. 9. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 6, hvor den første organiske syrebestanddel omfatter eddikesyre ved en koncentration på 0,2 - 0,4 vægt-% og den anden organiske syrebestanddel omfatter natriumbenzoat ved en koncentration på 0,2 - 0,4 vægt-%, eventuelt hvor tidsrummet er 24 timer, betingelserne indbefatter en temperatur på 40 °C, og pH’et er mellem 4 og 4,6.
  10. 10. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 9, hvor mindst ét af det ene eller flere fermenteringsbouilloner indeholder ét eller flere proteiner, der er sekreteret af cellerne, hvor eventuelt det mindst ene af det ene eller flere proteiner udtrykkes rekombinant af cellerne, og/eller mindst ét af det ene eller flere proteiner er et enzym, såsom en exoglucanase, en endoglucanase, en hemicellulase eller en β-glucosidase; hvor eventuelt mindst én af den ene eller flere fermenteringsbouilloner indeholder en flerhed af enzymer, der er udtrykt rekombinant og sekreteret af cellerne, for eksempel hvor flerheden af enzymer hver er en exoglucanase, en endoglucanase, en hemicellulase eller en β-glucosidase.
  11. 11. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 10, eller sammensætning ifølge krav 15 til 19, hvor proteiner udgør 5 til 15 vægtprocent af den første blanding.
  12. 12. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 11, der endvidere omfatter trinnet med tilsætning af et pH-justeringsmiddel, såsom phosphorsyre, svovlsyre eller natriumhydroxid, til den første blanding i løbet af inkubationsperioden.
  13. 13. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 12, hvor den første blanding endvidere omfatter ét eller flere antimikrobielle midler, såsom humleekstrakt, der indeholder iso-alfa-syrer, tetra-iso-alfa-syrer, og/eller beta-syrer, eventuelt i en mængde af 0,0005 til 0,05 vægt-% af den første blanding, såsom 0,001 til 0,025 vægt-% af den første blanding.
  14. 14. Fermenteringsbouillonformulering, der omfatter svampeceller, hvor fermenteringsbouillonformuleringen er opnået eller kan opnås ved hjælp af fremgangsmåden ifølge et hvilket som helst af kravene 1 til 13, der eventuelt omfatter ét eller flere ekstracellulære enzymer, der er udvalgt fra en exoglucanase, en endoglucanase, en hemicellulase og en β-glucosidase, hvilken bouillonformulering eventuelt har 2200 til 2800 CMC U/g endoglucanaseaktivitet og 525 til 775 pNPG U/g β-glucosidaseaktivitet, eller 2200 til 3200 CMC U/g endoglucanase, 300 til 800 pNPG U/g β-glucosidase aktivitet og 2000 til 5000 ABX U/g xylanaseaktivitet.
  15. 15. Sammensætning, der omfatter (a) én eller flere fermenteringsbouilloner, der omfatter svampeceller, for eksempel filamentøse svampeceller, såsom celler fra arterne Trichoderma, Aspergillus, Penicillium, Humicola, Chrysosporium eller Neurospora; (b) en første organisk syrebestanddel, der omfatter mindst én organisk syre med 1-5 kulstofatomer og/eller et salt deraf i en mængde af 0,2 til 1,5 vægt-% af sammensætningen, (c) en anden organisk syrebestanddel, der omfatter mindst én organisk syre med 6- eller flere kulstofatomer og/eller et salt deraf i en mængde af 0,04 til 0,6 vægt-% af sammensætningen, hvor den anden organiske syrebestanddel omfatter eller består af benzoesyre, et salt af benzoesyre, cyclohexancarboxylsyre, et salt af cyclohexancarboxylsyre, 4-methylvalerianesyre, et salt af 4-methylvalerianesyre, phenyleddikesyre, et salt af phenyleddikesyre eller en blanding af to eller flere af ovenstående; og hvor svampecellerne i overvejende grad eller fuldt ud er ikke-levedygtige celler, eventuelt hvor, hvis cellerne er levedygtige eller er til stede i sammensætningen, forholdet mellem ikke-levedygtige og levedygtige celler i sammensætningen er mindst 10:1, mindst 50:1, mindst 100:1, mindst 1000:1, mindst 10.000:1, mindst 100.000:1 eller mindst 1.000.000:1.
  16. 16. Sammensætning ifølge krav 15, der har et pH på 3,5 til 5, såsom et pH på 4 til 4,7, for eksempel et pH på 4,2 til 4,5.
  17. 17. Sammensætning ifølge et hvilket som helst af kravene 15 til 16, hvor den første organiske syrebestanddel omfatter eddikesyre ved en koncentration på 0,2 - 0,4 vægt-% og den anden organiske syrebestanddel omfatter natriumbenzoat ved en koncentration på 0,2 - 0,4 vægt-%.
  18. 18. Sammensætning ifølge et hvilket som helst af kravene 15 til 17, der omfatter ét eller flere proteiner, der er sekreteret af svampecellerne, hvor eventuelt mindst ét af det ene eller flere proteiner udtrykkes rekombinant af svampecellerne, og/eller hvor mindst ét af det ene eller flere proteiner er et enzym, såsom en exoglucanase, en endoglucanase, en hemicellulase eller en β-glucosidase; hvor eventuelt sammensætningen indeholder en flerhed af enzymer, der udtrykkes rekombinant og sekreteres af cellerne, såsom en flerhed af enzymer, der hvert er en exoglucanase, en endoglucanase, en hemicellulase eller en β-glucosidase.
  19. 19. Sammensætning ifølge et hvilket som helst af kravene 15 til 18, der endvidere omfatter ét eller flere antimikrobielle midler, såsom humleekstrakt, der indeholder iso-alfa-syrer, tetra-iso-alfa-syrer og/eller beta-syrer, eventuelt i en mængde af 0,0005 til 0,05 vægt-% af sammensætningen, såsom i en mængde af 0,001 til 0,025 vægt-% af sammensætningen.
  20. 20. Kit, der omfatter (a) emballering og (b) fermenteringsbouillonformuleringen ifølge krav 14 eller sammensætning ifølge et hvilket som helst af kravene 15 til 19.
DK10705512.1T 2009-02-20 2010-02-19 Fermenteringsbouillonformuleringer DK2398889T3 (da)

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US15423509P 2009-02-20 2009-02-20
US18586509P 2009-06-10 2009-06-10
US30421910P 2010-02-12 2010-02-12
PCT/US2010/024768 WO2010096673A1 (en) 2009-02-20 2010-02-19 Fermentation broth formulations

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JP (1) JP5663497B2 (da)
KR (1) KR20110124242A (da)
CN (1) CN102325872B (da)
AU (1) AU2010215867B2 (da)
BR (1) BRPI1008890A2 (da)
CA (1) CA2753075A1 (da)
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MX (1) MX2011008495A (da)
MY (1) MY158663A (da)
RU (1) RU2560424C2 (da)
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Families Citing this family (182)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012003091A (es) 2009-09-23 2012-04-30 Danisco Us Inc Enzimas de glicosil hidrolasa novedosas y usos de las mismas.
CN102686736B (zh) 2009-12-23 2017-05-31 丹尼斯科美国公司 提高同步糖化发酵反应效率的方法
US9303074B2 (en) 2010-08-30 2016-04-05 Novoyzmes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2012030811A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US8629325B2 (en) 2010-08-30 2014-01-14 Novozymes A/S Polypeptides having beta-glucosidase activity and polynucleotides encoding same
WO2012030844A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
US8624082B2 (en) 2010-08-30 2014-01-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
US20130212746A1 (en) 2010-08-30 2013-08-15 Novoyzmes A/S Polypeptides Having Hemicellulolytic Activity And Polynucleotides Encoding Same
BR112013007693B1 (pt) 2010-09-30 2021-12-07 Novozymes, Inc Variante, polinucleotídeo isolado, célula hospedeira microbiana recombinante, métodos para produzir uma variante, para produzir uma variante tendo atividade intensificadora celulolítica, para degradar um material celulósico, para produzir um produto de fermentação, para fermentar um material celulósico, e, composição enzimática, formulação do caldo completo ou composição de cultura de células
US9816082B2 (en) 2010-09-30 2017-11-14 Novozymes, Inc. Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN105886485B (zh) 2010-10-01 2019-09-24 诺维信股份有限公司 β-葡糖苷酶变体及其编码多核苷酸
BR112013010008B1 (pt) 2010-11-02 2020-09-08 Novozymes, Inc. Métodos para degradar e para fermentar um material celulósico, e para produzir um produto de fermentação
US9212354B2 (en) 2010-11-04 2015-12-15 Novozymes Inc. Polypeptides having cellobiohydrolase activitiy and polynucleotides encoding same
WO2012062220A1 (en) 2010-11-12 2012-05-18 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
EP2640833B1 (en) 2010-11-18 2016-08-24 Novozymes, Inc. Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2012103350A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
BR112013019038B1 (pt) 2011-01-26 2021-03-30 Novozymes A/S Célula hospedeira microbiana transgênica, métodos para produzir um polipeptídeo, para produzir uma proteína, para degradar um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico, e, construção de ácido nucleico ou vetor de expressão
MX2013007997A (es) 2011-02-23 2013-08-21 Novozymes Inc Polipeptidos que tienen actividad de incremento celulolitico y polinucleotidos que codifican para los mismos.
US9150842B2 (en) 2011-03-09 2015-10-06 Novozymes A/S Methods of increasing the cellulolytic enhancing activity of a polypeptide
WO2012122477A1 (en) 2011-03-10 2012-09-13 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
MX2013010512A (es) 2011-03-17 2013-10-07 Danisco Inc Metodo para reducir la viscosidad en un proceso de sacarificacion.
US9879294B2 (en) 2011-03-25 2018-01-30 Novozymes A/S Methods for degrading or converting cellulosic material
EP2691519A1 (en) 2011-03-31 2014-02-05 Novozymes, Inc. Cellulose binding domain variants and polynucleotides encoding same
WO2012135659A2 (en) 2011-03-31 2012-10-04 Novozymes A/S Methods for enhancing the degradation or conversion of cellulosic material
MX2013012325A (es) 2011-04-28 2013-11-01 Novozymes Inc Polipeptidos que tienen actividad de endoglucanasa y polinucleotidos que codifican los mismos.
WO2012149344A1 (en) 2011-04-29 2012-11-01 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
WO2012159007A1 (en) 2011-05-19 2012-11-22 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
EP2710133A1 (en) 2011-05-19 2014-03-26 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
CA2846398A1 (en) 2011-08-24 2013-02-28 Novozymes, Inc. Cellulolytic enzyme compositions and uses thereof
BR112014004193A2 (pt) 2011-08-24 2017-03-28 Novozymes Inc célula hospedeira recombinante de trichoderma, métodos para produzir uma composição enzimática, composição enzimática, processos para degradar um material celulósico, para sintetizar um produto de fermentação e para fermentar um material celulósico
WO2013043910A1 (en) 2011-09-20 2013-03-28 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
DK2760885T3 (da) 2011-09-30 2017-10-30 Novozymes Inc Kimære polypeptider med beta-glucosidaseaktivitet og polynukleotider, der koder for dem
CA2850070A1 (en) 2011-09-30 2013-04-04 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
UA116335C2 (uk) 2011-10-06 2018-03-12 Хамлет Протеїн А/С Спосіб суміщеного отримання ферментованого твердого продукту і етанолу, сирий етанол, ферментований твердий продукт та його застосування, харчова та кормова добавка, харчовий, кормовий, косметичний та фармацевтичний продукт
EP2773656B1 (en) 2011-10-31 2019-06-19 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP3409769A1 (en) 2011-11-18 2018-12-05 Novozymes A/S Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
EP3597736A1 (en) 2011-11-21 2020-01-22 Novozymes A/S Gh61 polypeptide variants and polynucleotides encoding same
EP3342860A1 (en) 2011-11-22 2018-07-04 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
BR112014012417A2 (pt) 2011-12-01 2017-06-06 Novozymes Inc polipeptídeo e polinucleotídeo isolados, célula hospedeira recombinante, métodos para a produção de um polipeptídeo, de um mutante de uma célula de origem, e de uma proteína, e para a inibição da expressão de um polipeptídeo, planta transgênica, parte da planta ou célula de planta, molécula de rna, processos para degradar ou converter um material celulósico ou contendo xilano, para produzir um produto de fermentação, e de fermentação de um material celulósico ou contendo xilano, e, formulação de caldo integral ou composição de cultura de células
EP3272862A1 (en) 2011-12-16 2018-01-24 Novozymes, Inc. Polypeptides having laccase activity and polynucleotides encoding same
WO2013091547A1 (en) 2011-12-19 2013-06-27 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
WO2013096603A2 (en) 2011-12-20 2013-06-27 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
US20150017670A1 (en) 2011-12-21 2015-01-15 Novozymes, Inc. Methods For Determining The Degradation Of A Biomass Material
CN104245926B (zh) 2012-04-27 2021-05-07 诺维信股份有限公司 Gh61多肽变体以及编码其的多核苷酸
AR090971A1 (es) 2012-05-07 2014-12-17 Novozymes As Polipeptidos que tienen actividad de degradacion de xantano y polinucleotidos que los codifican
US8759069B2 (en) * 2012-06-15 2014-06-24 E I Du Pont De Nemours And Company Contaminant control in Zymomonas fermentation using hop acids
BR112014029846A2 (pt) * 2012-07-06 2017-06-27 Novozymes As método de inativação da célula hospedeira microbiana em um caldo de fermentação
US9828595B2 (en) 2012-08-17 2017-11-28 Novozymes A/S Thermostable asparaginase variants and polynucleotides encoding same
US20150210991A1 (en) 2012-09-19 2015-07-30 Novozymes, Inc. Methods For Enhancing The Degradation Or Conversion Of Cellulosic Material
CN105861469B (zh) 2012-10-08 2020-04-14 诺维信公司 具有纤维素分解增强活性的多肽以及编码它们的多核苷酸
WO2014066141A2 (en) 2012-10-24 2014-05-01 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CA2892054A1 (en) 2012-12-07 2014-06-12 Ling Hua Compositions and methods of use
US9765373B2 (en) 2012-12-14 2017-09-19 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US20150337280A1 (en) 2012-12-19 2015-11-26 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
EP2938628A4 (en) 2012-12-24 2016-10-19 Novozymes As POLYPEPTIDES WITH ENDOGLUCANASE ACTIVITY AND POLYNUCLEOTIDES FOR CODING THEREOF
EP2964760B1 (en) 2013-03-08 2021-05-12 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
GB201308843D0 (en) 2013-03-14 2013-07-03 Verenium Corp Phytase formulation
US9850512B2 (en) 2013-03-15 2017-12-26 The Research Foundation For The State University Of New York Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield
CN105378050A (zh) 2013-04-18 2016-03-02 诺维信公司 具有蛋白酶活性的多肽和编码它们的多核苷酸
CA2910239A1 (en) 2013-05-10 2014-11-13 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
US20160083703A1 (en) 2013-05-17 2016-03-24 Novozymes A/S Polypeptides having alpha amylase activity
EP3011044A1 (en) 2013-06-21 2016-04-27 Novozymes A/S Production of polypeptides without secretion signal in bacillus
HUE040545T2 (hu) 2013-07-17 2019-03-28 Novozymes As Pullulanáz kimérák és az azokat kódoló polinukleotidok
US10167460B2 (en) 2013-07-29 2019-01-01 Danisco Us Inc Variant enzymes
EP3033420B1 (en) 2013-08-15 2018-02-21 Novozymes A/S Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same
JP6167758B2 (ja) * 2013-08-26 2017-07-26 王子ホールディングス株式会社 エタノールの製造方法
AU2014315208A1 (en) 2013-09-04 2016-01-28 Novozymes A/S Processes for increasing enzymatic hydrolysis of cellulosic material
WO2015081139A1 (en) 2013-11-26 2015-06-04 Novozymes A/S Enzyme compositions and uses thereof
CA2932239C (en) 2014-01-22 2023-03-14 Novozymes A/S Pullulanase variants and polynucleotides encoding same
US9951363B2 (en) 2014-03-14 2018-04-24 The Research Foundation for the State University of New York College of Environmental Science and Forestry Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects
CN106103708A (zh) 2014-04-01 2016-11-09 诺维信公司 具有α淀粉酶活性的多肽
US10131863B2 (en) 2014-04-11 2018-11-20 Novozymes A/S Detergent composition
CA2950273C (en) 2014-05-30 2022-06-21 Novozymes A/S Variants of gh family 11 xylanase and polynucleotides encoding same
DK3152315T3 (da) 2014-06-06 2018-11-26 Novozymes As Enzymsammensætninger og anvendelser deraf
CN106414729A (zh) 2014-06-12 2017-02-15 诺维信公司 α‑淀粉酶变体以及对其进行编码的多核苷酸
CN106795504A (zh) 2014-08-20 2017-05-31 诺维信公司 木葡聚糖内糖基转移酶变体以及编码其的多核苷酸
WO2016030480A1 (en) 2014-08-28 2016-03-03 Renescience A/S Solubilization of msw with blend enzymes
BR112017004251A2 (pt) 2014-09-05 2017-12-12 Novozymes As variantes de módulos de ligação a carboidrato e polinucleotídeos que os codificam
US10287562B2 (en) 2014-11-20 2019-05-14 Novoszymes A/S Alicyclobacillus variants and polynucleotides encoding same
WO2016087327A1 (en) 2014-12-01 2016-06-09 Novozymes A/S Polypeptides having pullulanase activity comprising the x25, x45 and cbm41 domains
US10781428B2 (en) 2014-12-02 2020-09-22 Novozymes A/S Laccase variants and polynucleotides encoding same
US10711259B2 (en) 2014-12-19 2020-07-14 Novozymes A/S Compositions comprising polypeptides having xylanase activity and polypeptides having arabinofuranosidase activity
US10557127B2 (en) 2015-02-24 2020-02-11 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
BR112017018461A2 (pt) 2015-03-12 2018-04-17 Novozymes As processos para hidrólise multiestágio, para produção de um produto de fermentação, e, para aumento de rendimento de açúcar de hidrólise.
WO2016145350A1 (en) 2015-03-12 2016-09-15 Novozymes A/S Multi-stage enzymatic hydrolysis of lignocellulosic biomass
BR112017019331A2 (pt) 2015-03-12 2018-06-05 Beta Renewables Spa processos para sacarificação de múltiplos estágios de um material lignocelulósico e para melhorar um rendimento de glicose ou xilose de sacarificação de um material lignocelulósico em um reator de tanque continuamente agitado
EP3277826A4 (en) * 2015-03-31 2018-10-31 Xyleco, Inc. Processing of biomass materials
WO2016169893A1 (en) 2015-04-20 2016-10-27 Dsm Ip Assets B.V. Whole fermentation broth
EP3964575A3 (en) 2015-05-08 2022-09-28 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
US10647946B2 (en) 2015-05-08 2020-05-12 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
US10519520B2 (en) 2015-05-27 2019-12-31 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2016196202A1 (en) 2015-05-29 2016-12-08 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
CN108350442A (zh) 2015-06-18 2018-07-31 诺维信公司 具有海藻糖酶活性的多肽及其在产生发酵产物的方法中的用途
US20180317514A1 (en) 2015-06-26 2018-11-08 Novozymes A/S Method for Producing a Coffee Extract
WO2016207373A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Polypeptides having peroxygenase activity
BR112017028065A2 (pt) 2015-06-26 2018-09-11 Novozymes As sistema de bioacabamento
WO2017019491A1 (en) 2015-07-24 2017-02-02 Novozymes Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
EP3325616A1 (en) 2015-07-24 2018-05-30 Novozymes, Inc. Polypeptides having arabinofuranosidase activity and polynucleotides encoding same
WO2017040907A1 (en) 2015-09-04 2017-03-09 Novozymes A/S Methods of inhibiting aa9 lytic polysaccharide monooxygenase catalyzed inactivation of enzyme compositions
CA2991114A1 (en) 2015-09-17 2017-03-23 Novozymes A/S Polypeptides having xanthan degrading activity and polynucleotides encoding same
CN108350044B (zh) 2015-09-22 2022-05-24 诺维信公司 具有纤维二糖水解酶活性的多肽以及对其进行编码的多核苷酸
US10934535B2 (en) 2015-10-07 2021-03-02 Novozymes A/S Detergent composition comprising a DNase
WO2017070219A1 (en) 2015-10-20 2017-04-27 Novozymes A/S Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same
WO2017076421A1 (en) 2015-11-02 2017-05-11 Renescience A/S Solubilization of msw with blend enzymes
WO2017129754A1 (en) 2016-01-29 2017-08-03 Novozymes A/S Beta-glucanase variants and polynucleotides encoding same
EP3423577B1 (en) 2016-03-02 2024-05-08 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
DK3433358T3 (da) 2016-03-24 2022-09-26 Novozymes As Cellobiohydrolasevarianter og polynukleotider, der koder for dem
CN109153981A (zh) 2016-05-24 2019-01-04 诺维信公司 具有α-半乳糖苷酶活性的多肽以及编码其的多核苷酸
US11058129B2 (en) 2016-05-24 2021-07-13 Novozymes A/S Animal feed additives
BR112018073283A2 (pt) 2016-05-24 2019-03-19 Novozymes A/S composição, grânulo, aditivo de ração para animal, ração para animal, ração para animal peletizada, formulação líquida, método para liberar galactose do material à base de planta, método para melhorar um ou mais parâmetros de desempenho de um animal, uso da composição, do grânulo, do aditivo de ração para animal ou da formulação líquida, polipeptídeo isolado, método para produzir o polipeptídeo, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, e, célula hospedeira
CN109312321A (zh) 2016-05-24 2019-02-05 诺维信公司 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物
WO2017205535A1 (en) 2016-05-27 2017-11-30 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
US20190256884A1 (en) 2016-07-07 2019-08-22 Novozymes A/S Methods of producing a fermentation product in trichoderma
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
CA3029113A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Xylanase variants and polynucleotides encoding same
US20190352627A1 (en) 2016-07-08 2019-11-21 Novozymes A/S Polypeptides having Xylanase Activity and Polynucleotides Encoding Same
US11326152B2 (en) 2016-07-18 2022-05-10 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
EP3487997B1 (en) 2016-07-20 2021-03-24 Novozymes A/S Heat-stable metagenomic carbonic anhydrases and their use
WO2018026868A1 (en) 2016-08-01 2018-02-08 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US20210284933A1 (en) 2016-10-25 2021-09-16 Novozymes A/S Detergent compositions
WO2018085370A1 (en) 2016-11-02 2018-05-11 Novozymes A/S Processes for reducing production of primeverose during enzymatic saccharification of lignocellulosic material
CN110072997A (zh) 2016-11-23 2019-07-30 诺维信公司 具有蛋白酶活性的多肽和编码其的多核苷酸
WO2018134386A1 (en) 2017-01-23 2018-07-26 Novozymes A/S Host cells and methods for producing double-stranded rna
US11051520B2 (en) 2017-02-20 2021-07-06 Novozymes A/S Lipolytic enzyme for use in baking
EP3601550A1 (en) 2017-03-31 2020-02-05 Novozymes A/S Polypeptides having dnase activity
WO2018177936A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
CN110651039A (zh) 2017-03-31 2020-01-03 诺维信公司 具有rna酶活性的多肽
EP3607039A1 (en) 2017-04-04 2020-02-12 Novozymes A/S Polypeptides
US11339355B2 (en) 2017-04-04 2022-05-24 Novozymes A/S Glycosyl hydrolases
EP3642339A1 (en) 2017-06-22 2020-04-29 Novozymes A/S Xylanase variants and polynucleotides encoding same
DK3645555T3 (da) 2017-06-28 2022-03-07 Novozymes As Polypeptider med trehalaseaktivitet og polynukleotider, der koder for disse
BR112020002115A2 (pt) 2017-08-08 2020-08-11 Novozymes A/S polipeptídeo variante de trealase, polinucleotídeo, construto de ácido nucleico, vetor de expressão, célula hospedeira, composição, formulação de caldo inteiro ou composição de cultura de células, método de produção de uma variante de trealase, e, processo de produção de um produto de fermentação
US11377650B2 (en) 2017-08-31 2022-07-05 Novozymes A/S Polypeptides having D-psicose 3 epimerase activity and polynucleotides encoding same
CN111050565A (zh) 2017-09-01 2020-04-21 诺维信公司 包含具有蛋白酶活性的多肽的动物饲料添加剂及其用途
MX2020002177A (es) 2017-09-01 2020-07-14 Novozymes As Aditivos para pienso para animales que comprenden un polipéptido que tiene actividad proteasa y usos de estos.
WO2019068715A1 (en) 2017-10-02 2019-04-11 Novozymes A/S POLYPEPTIDES HAVING MANNANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING THESE POLYPEPTIDES
CN111417725A (zh) 2017-10-02 2020-07-14 诺维信公司 具有甘露聚糖酶活性的多肽和编码它们的多核苷酸
WO2019070883A1 (en) 2017-10-04 2019-04-11 Novozymes A/S POLYPEPTIDES WITH PROTEASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
WO2019074828A1 (en) 2017-10-09 2019-04-18 Danisco Us Inc CELLOBIOSE DEHYDROGENASE VARIANTS AND METHODS OF USE
CN111417726A (zh) 2017-10-23 2020-07-14 诺维信公司 通过与前肽共表达改善蛋白酶的表达
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
WO2019096903A1 (en) 2017-11-20 2019-05-23 Novozymes A/S New galactanases (ec 3.2.1.89) for use in soy processing
EP3720955B1 (en) 2017-12-08 2023-06-14 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
MX2020005724A (es) 2017-12-08 2020-08-13 Novozymes As Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.
BR112020012577A2 (pt) * 2017-12-22 2020-11-24 Danisco Us Inc. método para aumentar a produção de aminoácidos em cultura de corynebacterium submersa
MX2020010526A (es) 2018-04-09 2021-01-08 Novozymes As Polipéptidos que tienen actividad alfa-amilasa ypolinucleótidos que los codifican.
WO2020070199A1 (en) 2018-10-03 2020-04-09 Novozymes A/S Polypeptides having alpha-mannan degrading activity and polynucleotides encoding same
BR112021011384A2 (pt) 2018-12-12 2022-05-17 Novozymes As Polipeptídeo isolado, composição de enzimas, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo isolado, célula hospedeira recombinante, método de produção de um polipeptídeo, planta, parte da planta ou célula da planta transgênica, e, processos para degradação de um material celulósico ou hemicelulósico, para produção de um produto de fermentação e de fermentação de um material celulósico ou hemicelulósico
WO2020127796A2 (en) 2018-12-21 2020-06-25 Novozymes A/S Polypeptides having peptidoglycan degrading activity and polynucleotides encoding same
WO2020156903A1 (en) 2019-01-30 2020-08-06 Novozymes A/S Cognate foldase co-expression
WO2020160126A1 (en) 2019-01-31 2020-08-06 Novozymes A/S Polypeptides having xylanase activity and use thereof for improving the nutritional quality of animal feed
CN113785056A (zh) 2019-03-08 2021-12-10 诺维信公司 改善蛋白酶表达的手段和方法
BR112021018137A2 (pt) 2019-03-18 2022-01-25 Novozymes As Pululanase variante, variante, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, composição, métodos de produção de uma pululanase variante e de produção de um mosto de cerveja, processos de produção de um xarope e de produção de produtos de fermentação, e, uso da célula hospedeira e da pululanase variante
EP3942032A1 (en) 2019-03-21 2022-01-26 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
CN113785039A (zh) 2019-04-03 2021-12-10 诺维信公司 具有β-葡聚糖酶活性的多肽、编码其的多核苷酸及其在清洁和洗涤剂组合物中的用途
CA3152952A1 (en) 2019-09-16 2021-03-25 Novozymes A/S Polypeptides having beta-glucanase activity and polynucleotides encoding same
WO2021064068A1 (en) 2019-10-03 2021-04-08 Novozymes A/S Polypeptides comprising at least two carbohydrate binding domains
CN110859192A (zh) * 2019-11-08 2020-03-06 宕昌县福江源药业科技有限责任公司 一种防治纹党参根腐病的制剂及其制备方法
AR120801A1 (es) 2019-12-19 2022-03-16 Novozymes As Variantes de xilanasa y polinucleótidos que codifican las mismas
WO2021123307A2 (en) 2019-12-20 2021-06-24 Novozymes A/S Polypeptides having proteolytic activity and use thereof
CN115052981A (zh) 2020-01-31 2022-09-13 诺维信公司 甘露聚糖酶变体以及编码它们的多核苷酸
EP4097226A1 (en) 2020-01-31 2022-12-07 Novozymes A/S Mannanase variants and polynucleotides encoding same
EP4103709A2 (en) 2020-02-10 2022-12-21 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
CN115210369A (zh) 2020-02-10 2022-10-18 诺维信公司 α-淀粉酶变体以及编码它们的多核苷酸
US20230235367A1 (en) 2020-02-10 2023-07-27 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
US11732278B1 (en) 2020-03-11 2023-08-22 Poet Research, Inc. Systems and methods for co-culture of oxygen sensitive bacteria and yeast
US11597950B1 (en) 2020-03-11 2023-03-07 Poet Research, Inc. Systems, compositions, and methods of fermentation with Z. mobilis
CN115516071A (zh) 2020-04-21 2022-12-23 诺维信公司 包含具有果聚糖降解活性的多肽的清洁组合物
US20230313209A1 (en) 2020-08-18 2023-10-05 Novozymes A/S Dispersins expressed with amylase signal peptides
CN116323889A (zh) 2020-08-25 2023-06-23 诺维信公司 家族44木葡聚糖酶变体
EP4204547A1 (en) 2020-08-28 2023-07-05 Novozymes A/S Protease variants with improved solubility
CN116507725A (zh) 2020-10-07 2023-07-28 诺维信公司 α-淀粉酶变体
CA3199315A1 (en) 2020-11-02 2022-05-05 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2022171780A2 (en) 2021-02-12 2022-08-18 Novozymes A/S Alpha-amylase variants
EP4359518A1 (en) 2021-06-23 2024-05-01 Novozymes A/S Alpha-amylase polypeptides
CN117730090A (zh) 2021-07-13 2024-03-19 诺维信公司 重组角质酶表达
WO2023118565A1 (en) 2021-12-23 2023-06-29 Novozymes A/S Reduction of residual dna in microbial fermentation products
WO2023170177A1 (en) 2022-03-08 2023-09-14 Novozymes A/S Fusion polypeptides with deamidase inhibitor and deamidase domains
EP4242303A1 (en) 2022-03-08 2023-09-13 Novozymes A/S Fusion polypeptides with deamidase inhibitor and deamidase domains
WO2024012912A1 (en) 2022-07-15 2024-01-18 Novozymes A/S Polypeptides having deamidase inhibitor activity
WO2024056643A1 (en) 2022-09-15 2024-03-21 Novozymes A/S Fungal signal peptides

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1333777C (en) 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi
CA2058633C (en) 1989-06-13 2000-03-21 Virgil B. Lawlis, Jr. A method for killing cells without lysis
US5801034A (en) * 1989-06-13 1998-09-01 Genencor International Method for killing cells without lysis and enzyme recovery
IL95019A0 (en) * 1989-08-09 1991-06-10 Mycogen Corp Process for encapsulation of biologicals
DE69133100T3 (de) 1990-12-10 2015-09-03 Danisco Us Inc. Verbesserte saccharifizierung von zellulose durch klonierung und vervielfältigung des beta-glukosidase genes aus trichoderma reesei
US5789210A (en) 1993-11-08 1998-08-04 Purdue Research Foundation Recombinant yeasts for effective fermentation of glucose and xylose
AU3066199A (en) * 1998-03-02 1999-09-20 University Of Georgia Research Foundation, Inc., The Reduction of bacterial pathogens on fresh food items
EP1078990A1 (de) * 1999-08-25 2001-02-28 Haarmann & Reimer Gmbh Fermentatives Verfahren zur Gewinnung natürlicher, aliphatischer und Thiocarbonsäuren und Mikroorganismus dafür
EP1133926A1 (en) * 2000-03-17 2001-09-19 Dsm N.V. Foodstuffs containing mucorales fungi
JP2004527261A (ja) 2001-05-18 2004-09-09 ノボザイムス アクティーゼルスカブ セロビアーゼ活性を有するポリペプチド及びそれをコードするポリヌクレオチド
US6982159B2 (en) 2001-09-21 2006-01-03 Genencor International, Inc. Trichoderma β-glucosidase
US7005289B2 (en) 2001-12-18 2006-02-28 Genencor International, Inc. BGL5 β-glucosidase and nucleic acids encoding the same
US7045332B2 (en) 2001-12-18 2006-05-16 Genencor International, Inc. BGL4 β-glucosidase and nucleic acids encoding the same
AU2003291395A1 (en) 2002-11-07 2004-06-03 Genencor International, Inc. Bgl6 beta-glucosidase and nucleic acids encoding the same
US7407788B2 (en) 2002-11-21 2008-08-05 Danisco A/S, Genencor Division BGL7 beta-glucosidase and nucleic acids encoding the same
EP1862626B1 (en) 2003-05-29 2011-09-14 Genencor International, Inc. Novel trichoderma genes
EP1570738A1 (en) * 2004-02-12 2005-09-07 Bayer CropScience S.A. Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the spores germination or mycelium growth by acting on different metabolic routes
EP2004820A1 (en) 2006-04-13 2008-12-24 DSMIP Assets B.V. Liquid composition comprising an aspartic protease
EP2032697A1 (en) 2006-06-26 2009-03-11 DSMIP Assets B.V. Peptidylarginine deiminase and uses thereof in the production of citrullinated proteins and peptides
CN101167480A (zh) * 2006-10-23 2008-04-30 黄永 一种微生物发酵液制成的组合制剂
CN100575480C (zh) * 2007-03-21 2009-12-30 珠海市农业科学研究中心 一株高效利用亚硝态氮的沼泽红假单胞菌及其应用
WO2008113799A1 (en) 2007-03-22 2008-09-25 Dsm Ip Assets B.V. Novel lysyl oxidases

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RU2560424C2 (ru) 2015-08-20
BRPI1008890A2 (pt) 2015-08-25
AU2010215867A1 (en) 2011-08-11
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CA2753075A1 (en) 2010-08-26
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US8679824B2 (en) 2014-03-25
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