DK222977A - Benzodiazocin-forbindelser til anvendelse som mellemprodukter ved fremstilling af terapeutisk virksomme benzodiazepin forbindelser samt fremgangsmade til fremstilling af benzodiazocinforbindelserne - Google Patents

Benzodiazocin-forbindelser til anvendelse som mellemprodukter ved fremstilling af terapeutisk virksomme benzodiazepin forbindelser samt fremgangsmade til fremstilling af benzodiazocinforbindelserne

Info

Publication number
DK222977A
DK222977A DK222977A DK222977A DK222977A DK 222977 A DK222977 A DK 222977A DK 222977 A DK222977 A DK 222977A DK 222977 A DK222977 A DK 222977A DK 222977 A DK222977 A DK 222977A
Authority
DK
Denmark
Prior art keywords
compounds
therapodic
binzodine
benzodia
benzodiazocine
Prior art date
Application number
DK222977A
Other languages
English (en)
Other versions
DK144969C (da
DK144969B (da
Inventor
W Milkowski
R Budden
S Funke
R Hueschens
H G Liepmann
W Stuehmer
H Zeugner
Original Assignee
Kali Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Ag filed Critical Kali Chemie Ag
Publication of DK222977A publication Critical patent/DK222977A/da
Publication of DK144969B publication Critical patent/DK144969B/da
Application granted granted Critical
Publication of DK144969C publication Critical patent/DK144969C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/5545—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having eight-membered rings not containing additional condensed or non-condensed nitrogen-containing 3-7 membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/04—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D245/06—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK222977A 1972-05-03 1977-05-20 6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazocin-forbindelser til anvendelse som mellemprodukter ved fremstilling af terapeutisk virksomme 5-phenyl-2,3-dihydro-1h-1,4-benzodiazepin-forbindelser samt fremgangsmaade til fremstilling af benzodiazocin-forbindelserne DK144969C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2221558 1972-05-03
DE2221558A DE2221558C2 (de) 1972-05-03 1972-05-03 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DK238573 1973-05-02
DK238573A DK147050C (da) 1972-05-03 1973-05-02 Fremgangsmaade til fremstilling af 5-phenyl-2,3-dihydro-1h-1,4-benzodiazepin-forbindelser eller syreadditionssalte deraf

Publications (3)

Publication Number Publication Date
DK222977A true DK222977A (da) 1977-05-20
DK144969B DK144969B (da) 1982-07-19
DK144969C DK144969C (da) 1982-12-06

Family

ID=5843904

Family Applications (3)

Application Number Title Priority Date Filing Date
DK238573A DK147050C (da) 1972-05-03 1973-05-02 Fremgangsmaade til fremstilling af 5-phenyl-2,3-dihydro-1h-1,4-benzodiazepin-forbindelser eller syreadditionssalte deraf
DK223077A DK223077A (da) 1972-05-03 1977-05-20 Acyldiamin forbindelser til anvendelse som mellemprodukter ved fremstillingen af terapeutisk virksomme benzodiazepinforbindelser
DK222977A DK144969C (da) 1972-05-03 1977-05-20 6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazocin-forbindelser til anvendelse som mellemprodukter ved fremstilling af terapeutisk virksomme 5-phenyl-2,3-dihydro-1h-1,4-benzodiazepin-forbindelser samt fremgangsmaade til fremstilling af benzodiazocin-forbindelserne

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK238573A DK147050C (da) 1972-05-03 1973-05-02 Fremgangsmaade til fremstilling af 5-phenyl-2,3-dihydro-1h-1,4-benzodiazepin-forbindelser eller syreadditionssalte deraf
DK223077A DK223077A (da) 1972-05-03 1977-05-20 Acyldiamin forbindelser til anvendelse som mellemprodukter ved fremstillingen af terapeutisk virksomme benzodiazepinforbindelser

Country Status (18)

Country Link
US (6) US3998809A (da)
JP (3) JPS5541231B2 (da)
AT (3) AT327927B (da)
BE (1) BE799001A (da)
CA (3) CA984388A (da)
CH (5) CH611609A5 (da)
DD (1) DD105222A5 (da)
DE (3) DE2265370C2 (da)
DK (3) DK147050C (da)
ES (1) ES414279A1 (da)
FR (3) FR2183735B1 (da)
GB (3) GB1429666A (da)
IL (5) IL42158A (da)
NL (1) NL179111C (da)
NO (6) NO142866C (da)
SE (3) SE409709B (da)
SU (2) SU526290A3 (da)
ZA (1) ZA733013B (da)

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DE3048264A1 (de) * 1980-12-20 1982-09-09 Kali-Chemie Pharma Gmbh, 3000 Hannover 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3124013A1 (de) * 1981-06-19 1982-12-30 Kali-Chemie Pharma Gmbh, 3000 Hannover 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3138769A1 (de) * 1981-09-30 1983-04-14 Kali-Chemie Pharma Gmbh, 3000 Hannover 7-brom-5-(2-halogenphenyl)-1h-2,3-dihydro-1,4- benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3151597A1 (de) * 1981-12-28 1983-07-07 Kali-Chemie Pharma Gmbh, 3000 Hannover (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3221402A1 (de) * 1982-06-05 1983-12-08 Kali-Chemie Pharma Gmbh, 3000 Hannover 5-phenyl-1,4-benzodiazepine enthaltende analgetisch wirksame pharmazeutische zubereitungen
US4493168A (en) * 1983-06-16 1985-01-15 Coburn Optical Industries, Inc. Calibration gauge for computer-controlled lens generator, or the like
US4786449A (en) * 1983-12-28 1988-11-22 Clowny Corporation Method for manufacture of multi-color marking implements
US4602886A (en) * 1983-12-28 1986-07-29 Smit Adrianus J Multi-color marking implement
US4684646A (en) * 1984-06-26 1987-08-04 Merck & Co., Inc. 2-acylaminomethyl-1,4-benzodiazepine derivatives as CCK-antagonists
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US5670640A (en) * 1996-02-02 1997-09-23 Hoffmann-La Roche Inc. Process for the manufacture of imidazodiazepine derivatives
EP0918773A1 (en) * 1996-07-01 1999-06-02 PHARMACIA & UPJOHN COMPANY Process for the production of 8-chloro-6-(2-fluorophenyl)-1-methyl-4h-imidazo 1,5-a]benzodiazepine
US6818607B1 (en) * 1999-08-27 2004-11-16 Procter & Gamble Company Bleach boosting components, compositions and laundry methods
CN1384867A (zh) 1999-08-27 2002-12-11 宝洁公司 稳定性提高的配制组分、使用该组分的组合物和洗衣方法
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US2785200A (en) * 1953-06-08 1957-03-12 Abbott Lab Dichlorobenzoyl-ethylenediamine
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US3577557A (en) * 1966-12-09 1971-05-04 Sandoz Ag Benzo(1,5)diazocinones
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JPS4728284Y1 (da) * 1970-09-14 1972-08-26
US4021224A (en) * 1971-12-09 1977-05-03 Stauffer Chemical Company Herbicide compositions
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Also Published As

Publication number Publication date
US4243585A (en) 1981-01-06
AT327919B (de) 1976-02-25
US3998809A (en) 1976-12-21
CA1020570A (en) 1977-11-08
DK147050B (da) 1984-03-26
IL47693A (en) 1978-07-31
CH620423A5 (da) 1980-11-28
DE2265370C2 (de) 1982-12-02
FR2183735A1 (da) 1973-12-21
IL47693A0 (en) 1975-10-15
GB1429666A (en) 1976-03-24
NL179111C (nl) 1986-07-16
GB1429665A (en) 1976-03-24
US4216167A (en) 1980-08-05
DK147050C (da) 1984-09-03
JPS5387385A (en) 1978-08-01
IL42158A (en) 1978-07-31
ES414279A1 (es) 1976-05-01
DE2221558C2 (de) 1982-12-02
JPS4941389A (da) 1974-04-18
ZA733013B (en) 1974-08-28
JPS5387333A (en) 1978-08-01
NO144386C (no) 1981-08-19
GB1429667A (en) 1976-03-24
NO145761C (no) 1982-05-26
NO751349L (da) 1973-11-06
IL48141A0 (en) 1975-11-25
FR2248278A1 (da) 1975-05-16
DK144969C (da) 1982-12-06
NL7305570A (da) 1973-11-06
CA984388A (en) 1976-02-24
NO142866B (no) 1980-07-28
US4098786A (en) 1978-07-04
SE422460B (sv) 1982-03-08
SU625607A3 (ru) 1978-09-25
AU5510173A (en) 1974-11-07
NO142476C (no) 1980-08-27
US4096141A (en) 1978-06-20
ATA143875A (de) 1975-05-15
ATA389973A (de) 1975-05-15
AT327920B (de) 1976-02-25
FR2296616A1 (fr) 1976-07-30
CH605834A5 (da) 1978-10-13
NO145761B (no) 1982-02-15
DK223077A (da) 1977-05-20
FR2183735B1 (da) 1976-09-03
NO144386B (no) 1981-05-11
NO793013L (no) 1973-11-06
NO761580L (da) 1973-11-06
IL42158A0 (en) 1973-07-30
NO780402L (no) 1973-11-06
AT327927B (de) 1976-02-25
DK144969B (da) 1982-07-19
NO144885B (no) 1981-08-24
US4595531A (en) 1986-06-17
DE2221558A1 (de) 1973-11-15
FR2248278B1 (da) 1977-11-04
NO142476B (no) 1980-05-19
JPS5813535B2 (ja) 1983-03-14
SE7614681L (sv) 1976-12-29
SE7614680L (sv) 1976-12-29
NO142866C (no) 1980-11-05
SU526290A3 (ru) 1976-08-25
SE409709B (sv) 1979-09-03
DD105222A5 (da) 1974-04-12
FR2296616B1 (da) 1979-04-20
BE799001A (fr) 1973-08-31
NO143347B (no) 1980-10-13
IL48141A (en) 1978-07-31
DE2265371C3 (de) 1980-12-11
CH611609A5 (da) 1979-06-15
NO793012L (no) 1973-11-06
DE2265371B2 (de) 1980-04-17
ATA389873A (de) 1975-05-15
JPS589101B2 (ja) 1983-02-18
JPS5541231B2 (da) 1980-10-22
NO144885C (no) 1981-12-02
CH611608A5 (da) 1979-06-15
CA1009232A (en) 1977-04-26
CH611607A5 (da) 1979-06-15
NO143347C (no) 1981-01-21

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