DK1870103T3 - Anvendelse af uridin i kombination med cholin i behandling af hukommelsesforsstyrrelse - Google Patents
Anvendelse af uridin i kombination med cholin i behandling af hukommelsesforsstyrrelseInfo
- Publication number
- DK1870103T3 DK1870103T3 DK07116909T DK07116909T DK1870103T3 DK 1870103 T3 DK1870103 T3 DK 1870103T3 DK 07116909 T DK07116909 T DK 07116909T DK 07116909 T DK07116909 T DK 07116909T DK 1870103 T3 DK1870103 T3 DK 1870103T3
- Authority
- DK
- Denmark
- Prior art keywords
- choline
- uridine
- treatment
- combination
- memory disorder
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9500298P | 1998-07-31 | 1998-07-31 | |
PCT/US1999/017235 WO2000006174A1 (en) | 1998-07-31 | 1999-07-30 | Methods for increasing cytidine levels in vivo and treating cytidine-dependent human diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1870103T3 true DK1870103T3 (da) | 2010-01-11 |
Family
ID=22248474
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09173495.4T DK2145627T3 (da) | 1998-07-31 | 1999-07-30 | Anvendelse af uridin i kombination med cholin til behandling af en humør-lidelse eller en følelsesmæssig lidelse. |
DK10075661.8T DK2329829T3 (da) | 1998-07-31 | 1999-07-30 | Anveldelse af uridin i kombination med cholin til behandling af neurologiske lidelser |
DK07116909T DK1870103T3 (da) | 1998-07-31 | 1999-07-30 | Anvendelse af uridin i kombination med cholin i behandling af hukommelsesforsstyrrelse |
DK99937631T DK1140104T3 (da) | 1998-07-31 | 1999-07-30 | Behandling af Alzheimer's sygdom ved forögelse af cytidinniveauer in vivo |
DK10075660.0T DK2322187T3 (da) | 1998-07-31 | 1999-07-30 | Anvendelse af uridin i kombination med cholin til behandling af hukommelses-lidelser |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09173495.4T DK2145627T3 (da) | 1998-07-31 | 1999-07-30 | Anvendelse af uridin i kombination med cholin til behandling af en humør-lidelse eller en følelsesmæssig lidelse. |
DK10075661.8T DK2329829T3 (da) | 1998-07-31 | 1999-07-30 | Anveldelse af uridin i kombination med cholin til behandling af neurologiske lidelser |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99937631T DK1140104T3 (da) | 1998-07-31 | 1999-07-30 | Behandling af Alzheimer's sygdom ved forögelse af cytidinniveauer in vivo |
DK10075660.0T DK2322187T3 (da) | 1998-07-31 | 1999-07-30 | Anvendelse af uridin i kombination med cholin til behandling af hukommelses-lidelser |
Country Status (11)
Country | Link |
---|---|
US (1) | US6989376B2 (da) |
EP (5) | EP2322187B1 (da) |
JP (1) | JP2003517437A (da) |
AT (2) | ATE446097T1 (da) |
CA (1) | CA2339008C (da) |
CY (1) | CY1110570T1 (da) |
DE (2) | DE69941586D1 (da) |
DK (5) | DK2145627T3 (da) |
ES (5) | ES2294850T3 (da) |
PT (5) | PT1870103E (da) |
WO (1) | WO2000006174A1 (da) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8143234B2 (en) | 1998-07-31 | 2012-03-27 | Massachusetts Institute Of Technology | Uridine administration improves phosphatide synthesis, synaptic transmission and cognitive function |
US20070004670A1 (en) * | 1998-07-31 | 2007-01-04 | Richard Wurtman | Compositions containing citicoline, and methods of use thereof |
US20060069061A1 (en) * | 1998-07-31 | 2006-03-30 | Dick Wurtman | Compositions containing uridine and choline, and methods utilizing same |
US8518882B2 (en) * | 1998-07-31 | 2013-08-27 | Massachusetts Institute Of Technology | Methods and compositions for ameliorating or inhibiting decline in memory or intelligence or improving same |
US20050203053A1 (en) * | 1999-07-30 | 2005-09-15 | Wurtman Richard J. | Uridine administration improves phosphatide synthesis, synaptic transmission and cogntive function |
US8314064B2 (en) * | 1998-07-31 | 2012-11-20 | Massachusetts Institute Of Technology | Uridine administration stimulates membrane production |
US7807654B2 (en) * | 1998-08-31 | 2010-10-05 | Wellstat Therapeutics Corporation | Compositions and methods for treatment of mitochondrial diseases |
US7915233B1 (en) | 1998-08-31 | 2011-03-29 | Wellstat Therapeutics Corporation | Compositions and methods for treatment of mitochondrial diseases |
US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
EP1274444B1 (en) * | 2000-03-16 | 2013-05-15 | THE McLEAN HOSPITAL CORPORATION | Cdp-choline and uridine for the treatment of alcohol abuse |
US6727231B1 (en) * | 2000-10-12 | 2004-04-27 | Repligen Corporation | Uridine therapy for patients with elevated purine levels |
NL1019368C2 (nl) * | 2001-11-14 | 2003-05-20 | Nutricia Nv | Preparaat voor het verbeteren van receptorwerking. |
EP1541154A1 (en) * | 2002-07-11 | 2005-06-15 | Yamasa Corporation | Medicinal composition for drug-induced neuropathy |
CN100430066C (zh) | 2002-11-08 | 2008-11-05 | 麦克莱恩医院 | 用于烟草依赖性和戒断治疗的化合物 |
WO2004058160A2 (en) * | 2002-12-20 | 2004-07-15 | The Mclean Hospital Corporation | Compounds for the normalization of the sleep/wake cycle |
WO2005034874A2 (en) * | 2003-10-08 | 2005-04-21 | The Mclean Hospital Corporation | Enhanced efficacy of omega-3 fatty acid therapy in the treatment of psychiatric disorders and other indications |
JP2007508315A (ja) * | 2003-10-08 | 2007-04-05 | ザ マクレーン ホスピタル コーポレーション | ω−3脂肪酸を含む組み合わせを用いて、精神障害、物質乱用障害、および他の障害を治療する方法 |
EP1750509A4 (en) * | 2004-05-13 | 2010-03-24 | Massachusetts Inst Technology | EFFECTS OF URIDINE ON THE RELEASE OF DOPAMINE |
EP1765364A4 (en) * | 2004-06-10 | 2010-09-22 | Mclean Hospital Corp | PYRIMIDINES, SUCH AS Z: B: CYTIDINE, IN THE TREATMENT OF PATIENTS WITH BIPOLAR DISORDER |
EP1765075A4 (en) * | 2004-06-10 | 2010-11-10 | Mclean Hospital Corp | PYRIMIDINES, IN PARTICULAR URIDINE, USED IN TREATMENTS ON PATIENTS WITH BIPOLAR DISORDERS |
US7947661B2 (en) | 2004-08-11 | 2011-05-24 | The Mclean Hospital Corporation | Compounds for the treatment of marihuana dependence, withdrawal, and usage |
AU2011253660B2 (en) * | 2004-09-15 | 2013-12-19 | Massachusetts Institute Of Technology | Compositions containing uridine, and methods utilizing same |
AU2005285090A1 (en) * | 2004-09-15 | 2006-03-23 | Massachusetts Institute Of Technology | Compositions containing uridine, and methods utilizing same |
HUE031206T2 (en) * | 2005-05-23 | 2017-06-28 | Massachusetts Inst Technology | Formulations and methods of application containing PUFA |
AU2012203650B2 (en) * | 2005-05-23 | 2014-09-18 | Massachusetts Institute Of Technology | Compositions containing PUFA and methods of use thereof |
KR101324076B1 (ko) | 2005-09-22 | 2013-10-31 | 유키지루시 메그밀크 가부시키가이샤 | 스핑고미엘린 함유 의약, 음식품 또는 사료 |
WO2007059762A1 (de) * | 2005-11-25 | 2007-05-31 | Gisela Susilo | Kombinationspräparate enthaltend physiologische zellmembran-bestandteile, einschliesslich phosphatidylserin, cholin und ein pyrimidinnukleos/tid |
ATE509624T1 (de) | 2005-12-23 | 2011-06-15 | Nutricia Nv | Zusammensetzung enthaltend mehrfach ungesättigte fettsäuren, proteine, mangan und/oder molybden und nukleotide/nukleoside, zur behandlung von demenz |
JP5140584B2 (ja) * | 2006-06-27 | 2013-02-06 | ヤマサ醤油株式会社 | 抗心理社会的ストレス剤 |
US7972633B2 (en) * | 2007-02-07 | 2011-07-05 | Applied Cognitive Sciences, LLC | Nutritional supplements for healthy memory and mental function |
CN105510850A (zh) * | 2007-11-02 | 2016-04-20 | 麻省理工学院 | 尿苷饮食添加顺应性方法及其用途 |
AU2009257353A1 (en) * | 2008-06-12 | 2009-12-17 | Repligen Corporation | Methods of treatment of bipolar disorder |
US20100041621A1 (en) * | 2008-08-15 | 2010-02-18 | Perry Renshaw | Methods and compositions for improving cognitive performance |
CN103906745B (zh) | 2011-09-30 | 2017-08-25 | 塔夫斯大学 | 用于治疗神经变性疾病的尿苷二磷酸衍生物、组合物和方法 |
WO2013066152A1 (en) | 2011-10-31 | 2013-05-10 | N.V. Nutricia | Method for improving executive function |
WO2014027882A1 (en) | 2012-08-13 | 2014-02-20 | N.V. Nutricia | Product and method for supporting uridine homeostasis |
US9163055B2 (en) | 2012-09-28 | 2015-10-20 | Tufts University | Methods for treating glaucoma using uridine diphosphate derivatives |
AR095442A1 (es) | 2013-03-13 | 2015-10-14 | Univ Tufts | Derivados de nucleósido de uridina, composiciones y métodos de uso |
WO2014160502A1 (en) | 2013-03-13 | 2014-10-02 | Tufts University | Uridine nucleoside derivatives, compositions and methods of use |
WO2015115885A1 (en) * | 2014-01-31 | 2015-08-06 | N.V. Nutricia | Method for reducing white matter lesions, white matter hyperintensities (wmh), leukoaraiosis or periventricular white matter disease in elderly |
WO2016053085A1 (en) * | 2014-09-30 | 2016-04-07 | N.V. Nutricia | Composition comprising a uridine source and butyrate producing fibres for preventing gastrointestinal disorders |
WO2016072842A1 (en) * | 2014-11-05 | 2016-05-12 | N.V. Nutricia | Method for preventing, reducing the risk of, or treating behavioral frontotemporal dementia |
WO2017069613A1 (en) | 2015-10-23 | 2017-04-27 | N.V. Nutricia | Method for improving recognition and/or working memory in hyperphenylalanimenia and phenylketonuria patients |
EP3439647B1 (en) | 2016-04-04 | 2023-03-22 | N.V. Nutricia | Composition for use in reducing or preventing global developmental delay in children |
KR20200116096A (ko) * | 2018-02-01 | 2020-10-08 | 웰스태트 테러퓨틱스 코포레이션 | 우리딘의 전신 전달을 위한 조성물 및 장치 |
CN114990176A (zh) * | 2022-05-26 | 2022-09-02 | 宁夏华吉生物有限公司 | 一种生产尿嘧啶核苷的方法 |
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DE2508474A1 (de) * | 1975-02-27 | 1976-09-02 | Boehringer Mannheim Gmbh | Infusions- und spuelfluessigkeiten zur behandlung von hirnoedemen |
DE2629845A1 (de) * | 1976-07-02 | 1978-01-05 | Geb Graze Erika Graze | Infusions- bzw. injektionsloesungen bzw. waessrige konzentrate zu deren bereitung zur therapeutischen restituion des zellulaeren energiestoffwechsels und der koerpereigenen regelfunktion |
US4221784A (en) * | 1979-04-05 | 1980-09-09 | Massachusetts Institute Of Technology | Process and composition for treating disorders by administering lecithin |
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US4609647A (en) * | 1985-05-28 | 1986-09-02 | Massachusetts Institute Of Technology | Cytidyl diphosphocholine-drug composition and process |
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IT1219667B (it) | 1988-06-21 | 1990-05-24 | Polifarma Spa | Impiego di uridina nel trattamento farmacologico di disturbi dovuti ad alterato equilibrio dopaminergico |
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JPH0722495B2 (ja) * | 1990-01-30 | 1995-03-15 | 美穂 田中 | クロレラ含有油脂食品 |
US5141943A (en) | 1990-04-12 | 1992-08-25 | Brown University Research Foundation | 5-benzyl barbiturate derivatives |
US5567689A (en) * | 1993-08-13 | 1996-10-22 | The Uab Research Foundation | Methods for increasing uridine levels with L-nucleosides |
US5700590A (en) * | 1994-01-10 | 1997-12-23 | Abbott Laboratories | Nutritional formula with ribo-nucleotides |
JPH07215879A (ja) * | 1994-02-02 | 1995-08-15 | Otsuka Pharmaceut Factory Inc | 抗ストレス組成物 |
DE9412374U1 (de) * | 1994-08-01 | 1994-09-22 | Rauch-Petz, Gisela G., Dr., 80803 München | Nahrungsergänzungsmittel |
JPH0930976A (ja) * | 1995-07-17 | 1997-02-04 | Otsuka Pharmaceut Factory Inc | 記憶低下改善剤 |
US5843024A (en) * | 1996-05-17 | 1998-12-01 | Breonics, Inc. | Solution and process for resuscitation and preparation of ischemically damaged tissue |
IT1290781B1 (it) * | 1996-05-28 | 1998-12-10 | Polifarma Spa | Agente attivo terapeutico per il trattamento di malattie degenerative neuronali. |
US5962459A (en) * | 1996-05-28 | 1999-10-05 | Polifarma S.P.A. | Therapeutic active agent for treatment of neuron degenerative diseases |
US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
RU2268732C2 (ru) * | 1999-02-23 | 2006-01-27 | Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния | Способы лечения митохондриальных нарушений |
JP2001233776A (ja) * | 2000-02-25 | 2001-08-28 | Yamasa Shoyu Co Ltd | 学習・記憶能低下改善剤およびその用途 |
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-
1999
- 1999-07-30 WO PCT/US1999/017235 patent/WO2000006174A1/en active IP Right Grant
- 1999-07-30 PT PT07116909T patent/PT1870103E/pt unknown
- 1999-07-30 PT PT99937631T patent/PT1140104E/pt unknown
- 1999-07-30 EP EP10075660.0A patent/EP2322187B1/en not_active Expired - Lifetime
- 1999-07-30 EP EP09173495.4A patent/EP2145627B1/en not_active Expired - Lifetime
- 1999-07-30 ES ES99937631T patent/ES2294850T3/es not_active Expired - Lifetime
- 1999-07-30 ES ES10075660.0T patent/ES2477568T3/es not_active Expired - Lifetime
- 1999-07-30 DE DE69941586T patent/DE69941586D1/de not_active Expired - Lifetime
- 1999-07-30 AT AT07116909T patent/ATE446097T1/de active
- 1999-07-30 JP JP2000562028A patent/JP2003517437A/ja active Pending
- 1999-07-30 PT PT91734954T patent/PT2145627E/pt unknown
- 1999-07-30 ES ES07116909T patent/ES2332669T3/es not_active Expired - Lifetime
- 1999-07-30 DK DK09173495.4T patent/DK2145627T3/da active
- 1999-07-30 US US09/363,748 patent/US6989376B2/en not_active Expired - Lifetime
- 1999-07-30 DK DK10075661.8T patent/DK2329829T3/da active
- 1999-07-30 AT AT99937631T patent/ATE374029T1/de active
- 1999-07-30 PT PT100756600T patent/PT2322187E/pt unknown
- 1999-07-30 ES ES10075661.8T patent/ES2478044T3/es not_active Expired - Lifetime
- 1999-07-30 EP EP07116909A patent/EP1870103B1/en not_active Expired - Lifetime
- 1999-07-30 DK DK07116909T patent/DK1870103T3/da active
- 1999-07-30 EP EP10075661.8A patent/EP2329829B1/en not_active Expired - Lifetime
- 1999-07-30 DK DK99937631T patent/DK1140104T3/da active
- 1999-07-30 ES ES09173495.4T patent/ES2476940T3/es not_active Expired - Lifetime
- 1999-07-30 PT PT100756618T patent/PT2329829E/pt unknown
- 1999-07-30 DE DE69937198T patent/DE69937198T2/de not_active Expired - Lifetime
- 1999-07-30 DK DK10075660.0T patent/DK2322187T3/da active
- 1999-07-30 CA CA002339008A patent/CA2339008C/en not_active Expired - Lifetime
- 1999-07-30 EP EP99937631A patent/EP1140104B1/en not_active Expired - Lifetime
-
2009
- 2009-12-01 CY CY20091101264T patent/CY1110570T1/el unknown
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