DK175286B1 - 1,2-Dithiol-3-thion-S-oxid-forbindelser til anvendelse som lægemidler - Google Patents

1,2-Dithiol-3-thion-S-oxid-forbindelser til anvendelse som lægemidler Download PDF

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Publication number
DK175286B1
DK175286B1 DK198902566A DK256689A DK175286B1 DK 175286 B1 DK175286 B1 DK 175286B1 DK 198902566 A DK198902566 A DK 198902566A DK 256689 A DK256689 A DK 256689A DK 175286 B1 DK175286 B1 DK 175286B1
Authority
DK
Denmark
Prior art keywords
dithiol
thione
carbon atoms
halogen
lower alkoxy
Prior art date
Application number
DK198902566A
Other languages
Danish (da)
English (en)
Other versions
DK256689D0 (da
DK256689A (da
Inventor
Daniel Jasserand
Dominique Biard
Marie-Odile Christen
Patrick Dansette
Daniel Mansuy
Amor Sassi
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of DK256689D0 publication Critical patent/DK256689D0/da
Publication of DK256689A publication Critical patent/DK256689A/da
Application granted granted Critical
Publication of DK175286B1 publication Critical patent/DK175286B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK198902566A 1988-05-27 1989-05-26 1,2-Dithiol-3-thion-S-oxid-forbindelser til anvendelse som lægemidler DK175286B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88401304 1988-05-27
EP88401304A EP0343303A1 (de) 1988-05-27 1988-05-27 Neue 1,2-Dithiol-3-thion-S-oxid-Verbindungen enthaltende Arzneimittel

Publications (3)

Publication Number Publication Date
DK256689D0 DK256689D0 (da) 1989-05-26
DK256689A DK256689A (da) 1989-11-28
DK175286B1 true DK175286B1 (da) 2004-08-09

Family

ID=8200390

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198902566A DK175286B1 (da) 1988-05-27 1989-05-26 1,2-Dithiol-3-thion-S-oxid-forbindelser til anvendelse som lægemidler

Country Status (22)

Country Link
US (1) US5096920A (ja)
EP (2) EP0343303A1 (ja)
JP (1) JP2718429B2 (ja)
KR (1) KR970011289B1 (ja)
CN (2) CN1027893C (ja)
AR (1) AR247207A1 (ja)
AU (1) AU624141B2 (ja)
CA (1) CA1332609C (ja)
DD (1) DD283820A5 (ja)
DE (1) DE58905106D1 (ja)
DK (1) DK175286B1 (ja)
DZ (1) DZ1340A1 (ja)
ES (1) ES2058386T3 (ja)
FI (1) FI88503C (ja)
GR (1) GR3009107T3 (ja)
HU (1) HU203745B (ja)
IE (1) IE63291B1 (ja)
IL (1) IL90407A0 (ja)
NO (1) NO172579C (ja)
NZ (1) NZ229274A (ja)
PT (1) PT90521B (ja)
ZA (1) ZA893037B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6437092B1 (en) * 1998-11-06 2002-08-20 Conjuchem, Inc. Conjugates of opioids and endogenous carriers
KR100484526B1 (ko) * 2002-11-13 2005-04-20 씨제이 주식회사 티온 유도체, 그 제조방법 및 약제학적 조성물
CN101463030B (zh) * 2009-01-09 2012-03-21 福建深纳生物工程有限公司 茴三硫的制备方法
CN103012394B (zh) * 2012-11-19 2015-03-25 苏州大学 一种罗丹宁衍生物及其制备方法
CN102993166B (zh) * 2012-12-13 2015-05-13 苏州大学 一种3h-1,2-二硫环戊烯-3-硫酮类化合物的制备方法与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE874447C (de) * 1944-08-22 1953-04-23 Bruno Dr Boettcher Verfahren zur Herstellung von 5-Thion-1, 2-dithiolen
US2556963A (en) * 1946-07-15 1951-06-12 Gaudin Olivier Benzenes containing sulfur in their allylic or propenylic side chains and process of preparing them
US2662899A (en) * 1950-07-29 1953-12-15 Stauffer Chemical Co Chlorinated cyclic organic trithiocarbonate and process for preparing same
US2688620A (en) * 1951-05-04 1954-09-07 Gaudin Olivier Trisulfureted heterocyclic compounds
US2816116A (en) * 1954-06-01 1957-12-10 Standard Oil Co 2-para-t-butyl phenyl trithione
US3225062A (en) * 1963-02-11 1965-12-21 American Cyanamid Co Process for 1,2-dithiole-3-thiones
US3214442A (en) * 1963-06-26 1965-10-26 American Cyanamid Co 4, 5-dicyano-1, 3-dithiole-2-thione oxide and its preparation
US3847943A (en) * 1972-09-08 1974-11-12 P Warner Preparing anethole trithione using sulfolane solvent

Also Published As

Publication number Publication date
KR890017241A (ko) 1989-12-15
NO892147D0 (no) 1989-05-26
IE63291B1 (en) 1995-04-05
IE891777L (en) 1989-11-27
CN1047171C (zh) 1999-12-08
DZ1340A1 (fr) 2004-09-13
DK256689D0 (da) 1989-05-26
FI892571A (fi) 1989-11-28
EP0343573B1 (de) 1993-08-04
NO172579C (no) 1993-08-11
NZ229274A (en) 1990-10-26
PT90521A (pt) 1989-11-30
CA1332609C (en) 1994-10-18
GR3009107T3 (ja) 1993-12-30
IL90407A0 (en) 1990-01-18
ZA893037B (en) 1989-12-27
JPH0219376A (ja) 1990-01-23
HUT49870A (en) 1989-11-28
FI88503B (fi) 1993-02-15
DD283820A5 (de) 1990-10-24
DK256689A (da) 1989-11-28
JP2718429B2 (ja) 1998-02-25
AU3521689A (en) 1989-11-30
EP0343573A1 (de) 1989-11-29
DE58905106D1 (de) 1993-09-09
CN1027893C (zh) 1995-03-15
US5096920A (en) 1992-03-17
AR247207A1 (es) 1994-11-30
CN1101348A (zh) 1995-04-12
HU203745B (en) 1991-09-30
NO172579B (no) 1993-05-03
KR970011289B1 (ko) 1997-07-09
FI892571A0 (fi) 1989-05-26
PT90521B (pt) 1994-10-31
FI88503C (fi) 1993-05-25
NO892147L (no) 1989-11-28
ES2058386T3 (es) 1994-11-01
EP0343303A1 (de) 1989-11-29
CN1039246A (zh) 1990-01-31
AU624141B2 (en) 1992-06-04

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