DK172843B1 - Rekombinant kolonistimulationsfaktor-1 (CFS-1), DNA-sekvenser, der koder for sådanne polypeptider og modificerede former de - Google Patents

Rekombinant kolonistimulationsfaktor-1 (CFS-1), DNA-sekvenser, der koder for sådanne polypeptider og modificerede former de Download PDF

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Publication number
DK172843B1
DK172843B1 DK198604746A DK474686A DK172843B1 DK 172843 B1 DK172843 B1 DK 172843B1 DK 198604746 A DK198604746 A DK 198604746A DK 474686 A DK474686 A DK 474686A DK 172843 B1 DK172843 B1 DK 172843B1
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DK
Denmark
Prior art keywords
csf
mcsf
polypeptide
gln
amino acid
Prior art date
Application number
DK198604746A
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Danish (da)
English (en)
Other versions
DK474686D0 (da
DK474686A (da
Inventor
Ernest Seigo Kawasaki
Martha Ballie Ladner
Mazie Yee Coyne
Alice Ming Wang
Peter Ralph
Janelle Noble Van Arsdell
Mary Kim Warren
Original Assignee
Chiron Corp
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Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DK474686D0 publication Critical patent/DK474686D0/da
Publication of DK474686A publication Critical patent/DK474686A/da
Application granted granted Critical
Publication of DK172843B1 publication Critical patent/DK172843B1/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK198604746A 1985-02-05 1986-10-03 Rekombinant kolonistimulationsfaktor-1 (CFS-1), DNA-sekvenser, der koder for sådanne polypeptider og modificerede former de DK172843B1 (da)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US69835985A 1985-02-05 1985-02-05
US69835985 1985-02-05
US72883485A 1985-04-30 1985-04-30
US72883485 1985-04-30
US74492485A 1985-06-14 1985-06-14
US74492485 1985-06-14
US75681485A 1985-07-18 1985-07-18
US75681485 1985-07-18
US82106886A 1986-01-21 1986-01-21
US82106886 1986-01-21
US8600238 1986-02-03
PCT/US1986/000238 WO1986004607A1 (en) 1985-02-05 1986-02-03 Recombinant colony stimulating factor-1

Publications (3)

Publication Number Publication Date
DK474686D0 DK474686D0 (da) 1986-10-03
DK474686A DK474686A (da) 1986-12-05
DK172843B1 true DK172843B1 (da) 1999-08-09

Family

ID=27542097

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198604746A DK172843B1 (da) 1985-02-05 1986-10-03 Rekombinant kolonistimulationsfaktor-1 (CFS-1), DNA-sekvenser, der koder for sådanne polypeptider og modificerede former de

Country Status (11)

Country Link
US (1) US5470569A (ja)
EP (1) EP0209601B1 (ja)
JP (2) JP2561255B2 (ja)
AU (2) AU594045B2 (ja)
BG (1) BG49941A3 (ja)
DE (1) DE3689391T2 (ja)
DK (1) DK172843B1 (ja)
FI (1) FI100972B (ja)
IL (1) IL77789A (ja)
NO (1) NO179109C (ja)
WO (1) WO1986004607A1 (ja)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573930A (en) * 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US6103224A (en) * 1985-02-05 2000-08-15 Chiron Corporation N∇2 CSF-1 (short form) and carboxy truncated fragments thereof
US5792450A (en) * 1985-02-05 1998-08-11 Chiron Corporation Purified human CSF-1
WO1986004607A1 (en) * 1985-02-05 1986-08-14 Cetus Corporation Recombinant colony stimulating factor-1
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
ATE92966T1 (de) * 1986-05-06 1993-08-15 Genetics Inst Herstellung von m-csf.
EP0249477A3 (en) * 1986-06-12 1988-01-20 Immunex Corporation Functional recombinant analog polypeptides devoid of hydrophobic amino acids
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
JP2644794B2 (ja) * 1986-10-24 1997-08-25 カイロン コーポレイション 新規な型のコロニー刺激因子―１
AU8313187A (en) * 1986-12-31 1988-07-07 Cetus Corporation Pharmaceutical composition of colony stimulating factor-i and granulocyte colony stimulating factor
IL86090A (en) * 1987-04-16 1993-03-15 Cetus Oncology Corp Production of purified, biologically active, bacterially produced recombinant human csf-1
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
EP0643972B1 (en) * 1987-09-22 2002-03-06 Chiron Corporation Use of recombinant colony stimulating factor-1 for the preparation of a medicament for cytomegalovirus infections
JP2791418B2 (ja) 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
WO1989010407A1 (en) * 1988-04-29 1989-11-02 Genetics Institute, Inc. Homogeneous dimeric m-csf and storage stable formulations thereof
US5888495A (en) * 1988-05-23 1999-03-30 Genetics Institute, Inc. Method of producing storage stable M-CSF lyophilizates
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
US5288487A (en) * 1989-02-28 1994-02-22 Morinaga Milk Industry Co., Ltd. Human monocyte-macrophage-CSF preparations
CA2011050C (en) * 1989-02-28 2000-08-08 Fumimaro Takaku Human monocyte-machrophage-csf preparations
JPH02225418A (ja) * 1989-02-28 1990-09-07 Morinaga Milk Ind Co Ltd 抗悪性腫瘍剤
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
WO1999024582A1 (en) * 1997-11-07 1999-05-20 Dalhousie University Novel reovirus-derived proteins, nucleic acids encoding same, and uses therefor
US7108852B2 (en) 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
AR045563A1 (es) * 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
US20070099239A1 (en) * 2005-06-24 2007-05-03 Raymond Tabibiazar Methods and compositions for diagnosis and monitoring of atherosclerotic cardiovascular disease

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6030291B2 (ja) * 1978-03-20 1985-07-16 森永乳業株式会社 人顆粒球の分化増殖を促進するｈｇｉ糖蛋白質、ｈｇｉ糖蛋白質の製造法及びｈｇｉ糖蛋白質を含有する白血球減少症治療剤
US4230697A (en) * 1978-07-03 1980-10-28 Morinaga Milk Industry Co. Ltd. Virus-inactivated HGI-glycoprotein capable of stimulating proliferation and differentiation of human granulocyte, process for preparing same and leukopenia curative containing same
US4342828A (en) * 1979-07-20 1982-08-03 Morinaga Milk Industry Co., Ltd. Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells
JPS5758629A (en) * 1980-09-25 1982-04-08 Morinaga Milk Ind Co Ltd Separating and purifying method of colonization stimulating factor and callicrein in human urine
JPS6030654B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒトコロニ−刺激因子の製造方法
US4438032A (en) 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4432895A (en) * 1982-11-24 1984-02-21 Hoffmann-La Roche Inc. Monomeric interferons
US4485017A (en) * 1982-12-22 1984-11-27 Cetus Corporation Isolation of human interferon by immunosorbent and high performance liquid chromatography
JPS59137417A (ja) * 1983-01-28 1984-08-07 Morinaga Milk Ind Co Ltd 人尿由来コロニ−形成刺激因子及びカリクレインの製造法
US4504586A (en) * 1983-02-03 1985-03-12 Amgen Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1
JPS6041615A (ja) * 1983-08-12 1985-03-05 Green Cross Corp:The コロニ−形成刺激因子の製造方法
US4658018A (en) * 1984-03-13 1987-04-14 Immunex Corporation Process for producing homogeneous colony stimulating factor
JPS61227526A (ja) * 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
WO1986004587A1 (en) * 1985-02-05 1986-08-14 Cetus Corporation Purification of native colony stimulating factor-1
WO1986004607A1 (en) * 1985-02-05 1986-08-14 Cetus Corporation Recombinant colony stimulating factor-1
JPS629323A (ja) * 1985-07-08 1987-01-17 Seiko Epson Corp 液晶素子の駆動方法
AU589731B2 (en) * 1985-11-27 1989-10-19 Genetics Institute, Llc Colony stimulating factor for the treatment of aids-type diseases
US4879227A (en) * 1986-05-06 1989-11-07 Genetics Institute, Inc. Production of a recombinant human colony stimulating factor
US4868119A (en) * 1986-12-11 1989-09-19 Genetics Institute, Inc. Hematopoietic growth factors
ATE92966T1 (de) * 1986-05-06 1993-08-15 Genetics Inst Herstellung von m-csf.
EP0249477A3 (en) * 1986-06-12 1988-01-20 Immunex Corporation Functional recombinant analog polypeptides devoid of hydrophobic amino acids
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ

Also Published As

Publication number Publication date
NO179109C (no) 1996-08-07
WO1986004607A1 (en) 1986-08-14
EP0209601B1 (en) 1993-12-15
BG49941A3 (en) 1992-03-16
DE3689391T2 (de) 1994-06-30
FI100972B (fi) 1998-03-31
EP0209601A1 (en) 1987-01-28
IL77789A (en) 1992-03-29
JPH07163391A (ja) 1995-06-27
FI864016A (fi) 1986-10-03
US5470569A (en) 1995-11-28
AU5013090A (en) 1990-11-01
JPS62501607A (ja) 1987-07-02
DK474686D0 (da) 1986-10-03
FI864016A0 (fi) 1986-10-03
DE3689391D1 (de) 1994-01-27
AU5517386A (en) 1986-08-26
NO863952L (no) 1986-10-03
NO179109B (no) 1996-04-29
JP2553829B2 (ja) 1996-11-13
DK474686A (da) 1986-12-05
JP2561255B2 (ja) 1996-12-04
NO863952D0 (no) 1986-10-03
AU626639B2 (en) 1992-08-06
AU594045B2 (en) 1990-03-01

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired