DK169383B1 - Lægemidler indeholdende 2-aminobenzothiazolforbindelser, 2-amino-benzothiazolforbindelser, fremgangsmåder til deres fremstilling og anvendelse af 2-aminobenzothiazolforbindelser til fremstilling af lægemidler. - Google Patents

Lægemidler indeholdende 2-aminobenzothiazolforbindelser, 2-amino-benzothiazolforbindelser, fremgangsmåder til deres fremstilling og anvendelse af 2-aminobenzothiazolforbindelser til fremstilling af lægemidler. Download PDF

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Publication number
DK169383B1
DK169383B1 DK633489A DK633489A DK169383B1 DK 169383 B1 DK169383 B1 DK 169383B1 DK 633489 A DK633489 A DK 633489A DK 633489 A DK633489 A DK 633489A DK 169383 B1 DK169383 B1 DK 169383B1
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DK
Denmark
Prior art keywords
group
hydrogen atom
polyfluoroalkoxy
compounds
formula
Prior art date
Application number
DK633489A
Other languages
Danish (da)
English (en)
Other versions
DK633489A (da
DK633489D0 (da
Inventor
Francois Audiau
Claude James
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8816548A external-priority patent/FR2640624B1/fr
Priority claimed from FR8909484A external-priority patent/FR2649705B2/fr
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of DK633489D0 publication Critical patent/DK633489D0/da
Publication of DK633489A publication Critical patent/DK633489A/da
Application granted granted Critical
Publication of DK169383B1 publication Critical patent/DK169383B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK633489A 1988-12-15 1989-12-14 Lægemidler indeholdende 2-aminobenzothiazolforbindelser, 2-amino-benzothiazolforbindelser, fremgangsmåder til deres fremstilling og anvendelse af 2-aminobenzothiazolforbindelser til fremstilling af lægemidler. DK169383B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8816548 1988-12-15
FR8816548A FR2640624B1 (fr) 1988-12-15 1988-12-15 Medicaments a base de derives de la benzothiazolamine-2, nouveaux derives et leur preparation
FR8909484A FR2649705B2 (fr) 1989-07-13 1989-07-13 Medicaments a base de derives de la benzothiazolamine-2, nouveaux derives et leur preparation
FR8909484 1989-07-13

Publications (3)

Publication Number Publication Date
DK633489D0 DK633489D0 (da) 1989-12-14
DK633489A DK633489A (da) 1990-06-16
DK169383B1 true DK169383B1 (da) 1994-10-17

Family

ID=26227051

Family Applications (1)

Application Number Title Priority Date Filing Date
DK633489A DK169383B1 (da) 1988-12-15 1989-12-14 Lægemidler indeholdende 2-aminobenzothiazolforbindelser, 2-amino-benzothiazolforbindelser, fremgangsmåder til deres fremstilling og anvendelse af 2-aminobenzothiazolforbindelser til fremstilling af lægemidler.

Country Status (11)

Country Link
EP (1) EP0374041B1 (sv)
JP (1) JPH0749425B2 (sv)
CA (1) CA2005592A1 (sv)
DE (1) DE68901859T2 (sv)
DK (1) DK169383B1 (sv)
ES (1) ES2043070T3 (sv)
FI (1) FI93108C (sv)
GR (1) GR3004937T3 (sv)
IE (1) IE64657B1 (sv)
NO (1) NO173061C (sv)
PT (1) PT92606B (sv)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US6413948B1 (en) 1996-09-27 2002-07-02 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of effecting a neuronal activity in an animal using naaladase inhibitors

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2684992B1 (fr) * 1991-12-13 1994-02-04 Rhone Poulenc Rorer Sa Procede de preparation d'amino-2 nitro-7 benzothiazoles.
FR2684993B1 (fr) * 1991-12-13 1994-02-04 Rhone Poulenc Rorer Sa Procede de preparation de derives d'amino-2 nitro-4 benzothiazole et intermediaires.
FR2714828B1 (fr) * 1994-01-12 1996-02-02 Rhone Poulenc Rorer Sa Application du riluzole dans le traitement des maladies mitochondriales.
FR2726271B1 (fr) * 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole
FR2741803A1 (fr) * 1995-12-01 1997-06-06 Rhone Poulenc Rorer Sa Application de 2-aminobenzothiazoles dans le traitement de la maladie de parkinson et des syndromes parkinsoniens
FR2774592B1 (fr) * 1998-02-06 2000-03-17 Rhone Poulenc Rorer Sa Application du 2-amino-6-trifluoromethoxybenzothiazole pour la prevention ou le traitement des dysfonctionnements du cervelet
AU4537500A (en) 1999-05-12 2000-12-05 Neurosearch A/S Ion channel modulating agents
EP1416931B1 (en) * 2001-08-13 2007-06-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Inhibitors of polyq-aggregation
CN110709386B (zh) * 2017-03-30 2022-06-07 凯瑞康宁生物工程（武汉）有限公司 双环杂芳基衍生物及其制备与用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
JPS63190880A (ja) * 1986-09-09 1988-08-08 Nippon Tokushu Noyaku Seizo Kk 新規ｎ−ベンゾチアゾリル−アミド類及び殺虫剤
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US5985855A (en) 1996-09-27 1999-11-16 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using NAALADase inhibitors
US6004946A (en) 1996-09-27 1999-12-21 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US6413948B1 (en) 1996-09-27 2002-07-02 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of effecting a neuronal activity in an animal using naaladase inhibitors

Also Published As

Publication number Publication date
NO895032D0 (no) 1989-12-14
IE894008L (en) 1990-06-15
NO173061B (no) 1993-07-12
JPH02223571A (ja) 1990-09-05
NO173061C (no) 1993-10-20
EP0374041A1 (fr) 1990-06-20
GR3004937T3 (sv) 1993-04-28
IE64657B1 (en) 1995-08-23
DK633489A (da) 1990-06-16
JPH0749425B2 (ja) 1995-05-31
FI93108B (sv) 1994-11-15
ES2043070T3 (es) 1993-12-16
FI93108C (sv) 1995-02-27
NO895032L (no) 1990-06-18
DE68901859D1 (de) 1992-07-23
DE68901859T2 (de) 1993-01-14
DK633489D0 (da) 1989-12-14
EP0374041B1 (fr) 1992-06-17
PT92606A (pt) 1990-06-29
PT92606B (pt) 1995-09-12
FI895983A0 (sv) 1989-12-14
CA2005592A1 (fr) 1990-06-15

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