DK1689777T3 - Fremgangsmåde til oprensning af il18-bindende protein - Google Patents

Fremgangsmåde til oprensning af il18-bindende protein

Info

Publication number
DK1689777T3
DK1689777T3 DK04798163T DK04798163T DK1689777T3 DK 1689777 T3 DK1689777 T3 DK 1689777T3 DK 04798163 T DK04798163 T DK 04798163T DK 04798163 T DK04798163 T DK 04798163T DK 1689777 T3 DK1689777 T3 DK 1689777T3
Authority
DK
Denmark
Prior art keywords
binding protein
purifying
purification
fluid
relates
Prior art date
Application number
DK04798163T
Other languages
Danish (da)
English (en)
Inventor
Mara Rossi
Thierry Ziegler
Laure Valognes
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of DK1689777T3 publication Critical patent/DK1689777T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK04798163T 2003-11-05 2004-11-04 Fremgangsmåde til oprensning af il18-bindende protein DK1689777T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51744703P 2003-11-05 2003-11-05
EP03104092 2003-11-05
PCT/EP2004/052807 WO2005049649A1 (en) 2003-11-05 2004-11-04 Process for the purification of il-18 binding protein

Publications (1)

Publication Number Publication Date
DK1689777T3 true DK1689777T3 (da) 2007-06-11

Family

ID=34924126

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04798163T DK1689777T3 (da) 2003-11-05 2004-11-04 Fremgangsmåde til oprensning af il18-bindende protein

Country Status (19)

Country Link
US (1) US7820800B2 (no)
EP (1) EP1689777B1 (no)
JP (1) JP4741504B2 (no)
AT (1) ATE360647T1 (no)
AU (1) AU2004291341B2 (no)
CA (1) CA2544146C (no)
CY (1) CY1106683T1 (no)
DE (1) DE602004006157T2 (no)
DK (1) DK1689777T3 (no)
ES (1) ES2285543T3 (no)
HR (1) HRP20070196T3 (no)
IL (1) IL175431A (no)
ME (1) ME01198B (no)
NO (1) NO330538B1 (no)
PL (1) PL1689777T3 (no)
PT (1) PT1689777E (no)
RS (1) RS50516B (no)
SI (1) SI1689777T1 (no)
WO (1) WO2005049649A1 (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0408246A (pt) * 2003-03-11 2006-03-01 Applied Research Systems vetores de expressão que compreendem o promotor ie2 do mcmv
ES2384241T3 (es) * 2003-05-13 2012-07-02 Merck Serono Sa Variantes activas de la proteína que fija IL-18 y usos médicos de las mismas
PT1675956E (pt) * 2003-10-21 2010-11-04 Merck Serono Sa Sequência mínima de adn que actua como um isolador de cromatina e sua utilização na expressão de proteína
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
WO2005083058A1 (en) * 2004-03-01 2005-09-09 Ares Trading S.A. Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
EP1761552B1 (en) * 2004-06-29 2008-09-17 Ares Trading S.A. Process for the purification of il-18 binding protein
WO2006110277A1 (en) 2005-04-11 2006-10-19 Medarex, Inc. Protein purification using hcic amd ion exchange chromatography
ATE557038T1 (de) * 2005-06-03 2012-05-15 Ares Trading Sa Herstellung von rekombinantem il-18 bindendem protein
EP1891088B1 (en) * 2005-06-10 2011-10-19 Ares Trading S.A. Process for the purification of il-18 binding protein
WO2009041643A1 (ja) 2007-09-26 2009-04-02 Chugai Seiyaku Kabushiki Kaisha Cdrのアミノ酸置換により抗体の等電点を改変する方法
EP2245044A2 (en) 2008-01-18 2010-11-03 F. Hoffmann-La Roche AG Purification of non-glycosylated proteins
JP4954326B2 (ja) * 2008-04-11 2012-06-13 中外製薬株式会社 複数分子の抗原に繰り返し結合する抗原結合分子
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
WO2011156369A2 (en) * 2010-06-07 2011-12-15 Dr. Reddy's Laboratories Ltd. Purification of modified cytokines
EP4231014A3 (en) 2010-11-30 2024-03-20 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
US20140093496A1 (en) 2011-02-25 2014-04-03 Chugai Seiyaku Kabushiki Kaisha Fc-gamma-RIIb-SPECIFIC Fc ANTIBODY
CA2831787A1 (en) 2011-03-29 2012-10-04 Glaxosmithkline Llc Buffer system for protein purification
EP2762493B1 (en) 2011-09-30 2021-06-09 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
TW201326209A (zh) 2011-09-30 2013-07-01 Chugai Pharmaceutical Co Ltd 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子
KR20210074395A (ko) 2011-11-30 2021-06-21 추가이 세이야쿠 가부시키가이샤 면역 복합체를 형성하는 세포내로의 운반체（캐리어）를 포함하는 의약
KR102318483B1 (ko) 2013-04-02 2021-10-27 추가이 세이야쿠 가부시키가이샤 Ｆｃ영역 개변체
KR101921552B1 (ko) * 2014-03-10 2018-11-23 리히터 게데온 닐트. 사전 세정 단계를 이용하는 면역글로불린 정제
CN107001411B (zh) 2014-12-15 2021-07-23 默克专利股份公司 从粗溶液捕获靶分子
EA201791366A1 (ru) 2014-12-19 2018-02-28 Чугаи Сейяку Кабусики Кайся Антитела к c5 и способы их применения
MY181199A (en) 2014-12-19 2020-12-21 Chugai Pharmaceutical Co Ltd Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
CN107108729A (zh) 2015-02-05 2017-08-29 中外制药株式会社 包含离子浓度依赖性的抗原结合结构域的抗体，fc区变体，il‑8‑结合抗体，及其应用
BR112017014067B1 (pt) 2015-02-27 2021-01-12 Chugai Seiyaku Kabushiki Kaisha usos de um anticorpo receptor de il-6 para no tratamento de doenças relacionadas a il-6
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
KR20230079499A (ko) 2016-08-05 2023-06-07 추가이 세이야쿠 가부시키가이샤 Il-8 관련 질환의 치료용 또는 예방용 조성물
JP7191833B2 (ja) 2017-01-30 2022-12-19 中外製薬株式会社 抗スクレロスチン抗体およびその使用
WO2018203545A1 (ja) 2017-05-02 2018-11-08 国立研究開発法人国立精神・神経医療研究センター Ｉｌ－６及び好中球の関連する疾患の治療効果の予測及び判定方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121860A0 (en) 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
WO2000012555A1 (fr) 1998-09-01 2000-03-09 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Proteine de liaison de l'interleukine 18
JP4216950B2 (ja) * 1998-09-01 2009-01-28 株式会社林原生物化学研究所 インターロイキン−１８結合蛋白質
US20020052475A1 (en) * 2000-07-20 2002-05-02 Schering Ag High affinity soluble interleukin-18 receptor
AU2002324249B2 (en) * 2001-03-08 2007-04-05 Ares Trading S.A. Interleukin-18 mutants, their production and use
CN1547486A (zh) * 2001-06-26 2004-11-17 抗opgl抗体
US20040018573A1 (en) * 2002-04-18 2004-01-29 Power Scott D Production of functional antibodies in filamentous fungi
BRPI0408246A (pt) * 2003-03-11 2006-03-01 Applied Research Systems vetores de expressão que compreendem o promotor ie2 do mcmv
ES2384241T3 (es) 2003-05-13 2012-07-02 Merck Serono Sa Variantes activas de la proteína que fija IL-18 y usos médicos de las mismas
PT1675956E (pt) 2003-10-21 2010-11-04 Merck Serono Sa Sequência mínima de adn que actua como um isolador de cromatina e sua utilização na expressão de proteína
WO2005083058A1 (en) * 2004-03-01 2005-09-09 Ares Trading S.A. Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
EP1761552B1 (en) 2004-06-29 2008-09-17 Ares Trading S.A. Process for the purification of il-18 binding protein
ATE557038T1 (de) 2005-06-03 2012-05-15 Ares Trading Sa Herstellung von rekombinantem il-18 bindendem protein
EP1891088B1 (en) * 2005-06-10 2011-10-19 Ares Trading S.A. Process for the purification of il-18 binding protein

Also Published As

Publication number Publication date
JP4741504B2 (ja) 2011-08-03
ME01198B (me) 2013-03-20
AU2004291341A1 (en) 2005-06-02
CY1106683T1 (el) 2012-05-23
IL175431A (en) 2011-02-28
PT1689777E (pt) 2007-05-31
DE602004006157D1 (de) 2007-06-06
ATE360647T1 (de) 2007-05-15
US7820800B2 (en) 2010-10-26
SI1689777T1 (sl) 2007-08-31
WO2005049649A1 (en) 2005-06-02
NO330538B1 (no) 2011-05-09
DE602004006157T2 (de) 2008-01-03
PL1689777T3 (pl) 2007-09-28
HRP20070196T3 (en) 2007-06-30
IL175431A0 (en) 2006-09-05
CA2544146C (en) 2012-10-02
EP1689777A1 (en) 2006-08-16
NO20062545L (no) 2006-08-03
JP2007533651A (ja) 2007-11-22
AU2004291341B2 (en) 2010-08-05
ES2285543T3 (es) 2007-11-16
CA2544146A1 (en) 2005-06-02
EP1689777B1 (en) 2007-04-25
RS50516B (sr) 2010-05-07
US20070037734A1 (en) 2007-02-15

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