RS50516B - Prečišćavanje il-18 vezujućeg proteina - Google Patents

Prečišćavanje il-18 vezujućeg proteina

Info

Publication number
RS50516B
RS50516B RSP-2007/0216A RSP20070216A RS50516B RS 50516 B RS50516 B RS 50516B RS P20070216 A RSP20070216 A RS P20070216A RS 50516 B RS50516 B RS 50516B
Authority
RS
Serbia
Prior art keywords
binding protein
purification
charge
application contains
hydrophobic chromatography
Prior art date
Application number
RSP-2007/0216A
Other languages
English (en)
Inventor
Mara Rossi
Thierry Ziegler
Laure Valognes
Original Assignee
Ares Trading S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading S.A. filed Critical Ares Trading S.A.
Publication of RS50516B publication Critical patent/RS50516B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Upotreba hidrofobne hromatografije sa indukcijom naelektrisanja za produkciju purifikovanog IL-18 vezujućeg proteina (IL-18BP). Prijava sadrži 1+20 patentnih zahteva.
RSP-2007/0216A 2003-11-05 2004-11-04 Prečišćavanje il-18 vezujućeg proteina RS50516B (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51744703P 2003-11-05 2003-11-05
EP03104092 2003-11-05
PCT/EP2004/052807 WO2005049649A1 (en) 2003-11-05 2004-11-04 Process for the purification of il-18 binding protein

Publications (1)

Publication Number Publication Date
RS50516B true RS50516B (sr) 2010-05-07

Family

ID=34924126

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2007/0216A RS50516B (sr) 2003-11-05 2004-11-04 Prečišćavanje il-18 vezujućeg proteina

Country Status (19)

Country Link
US (1) US7820800B2 (sr)
EP (1) EP1689777B1 (sr)
JP (1) JP4741504B2 (sr)
AT (1) ATE360647T1 (sr)
AU (1) AU2004291341B2 (sr)
CA (1) CA2544146C (sr)
CY (1) CY1106683T1 (sr)
DE (1) DE602004006157T2 (sr)
DK (1) DK1689777T3 (sr)
ES (1) ES2285543T3 (sr)
HR (1) HRP20070196T3 (sr)
IL (1) IL175431A (sr)
ME (1) ME01198B (sr)
NO (1) NO330538B1 (sr)
PL (1) PL1689777T3 (sr)
PT (1) PT1689777E (sr)
RS (1) RS50516B (sr)
SI (1) SI1689777T1 (sr)
WO (1) WO2005049649A1 (sr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
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SI1601776T1 (sl) 2003-03-11 2008-10-31 Serono Lab Ekspresijski vektorji, ki vsebujejo mcmv ie2 promotor
CA2524403C (en) * 2003-05-13 2013-07-09 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
ES2354160T3 (es) 2003-10-21 2011-03-10 Merck Serono Sa Secuencia de adn mínima que actúa como un aislante de cromatina, y su uso en la expresión de proteínas.
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
ME01218B (me) 2004-03-01 2013-06-20 Ares Trading Sa Upotreba podloge za ćelijsku strukturu bez sadrzaja seruma za produkciju il-18bp u ćelijama sisara
ATE408616T1 (de) 2004-06-29 2008-10-15 Ares Trading Sa Verfahren zur aufreinigung von il-18-bindendem protein
KR20080006601A (ko) 2005-04-11 2008-01-16 메다렉스, 인코포레이티드 단백질 정제 방법
US7691611B2 (en) * 2005-06-03 2010-04-06 Ares Trading S.A. Production of recombinant IL-18 binding protein
JP5091127B2 (ja) 2005-06-10 2012-12-05 アレス トレーディング ソシエテ アノニム Ｉｌ−１８結合タンパク質の精製のための方法
CN101874042B9 (zh) 2007-09-26 2019-01-01 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
CA2711375C (en) 2008-01-18 2019-04-16 F. Hoffmann-La Roche Ag Purification of not-glycosylated polypeptides
LT2708559T (lt) * 2008-04-11 2018-06-11 Chugai Seiyaku Kabushiki Kaisha Antigeną surišanti molekulė, galinti pakartotinai prisijungti prie dviejų ar daugiau antigeno molekulių
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
WO2011156369A2 (en) * 2010-06-07 2011-12-15 Dr. Reddy's Laboratories Ltd. Purification of modified cytokines
EP2647706B1 (en) 2010-11-30 2023-05-17 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
MX352889B (es) 2011-02-25 2017-12-13 Chugai Pharmaceutical Co Ltd Anticuerpo de fc especifico para fcyriib.
ES2784628T3 (es) 2011-03-29 2020-09-29 Glaxosmithkline Llc Sistema de tampón para purificación de proteína
TW201817745A (zh) 2011-09-30 2018-05-16 日商中外製藥股份有限公司 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子
US20150050269A1 (en) 2011-09-30 2015-02-19 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
MX358220B (es) 2011-11-30 2018-08-10 Chugai Pharmaceutical Co Ltd Portador que contiene fármaco en la célula para formar el inmunocomplejo.
AU2014250434B2 (en) 2013-04-02 2019-08-08 Chugai Seiyaku Kabushiki Kaisha Fc region variant
PL3116891T3 (pl) * 2014-03-10 2020-07-27 Richter Gedeon Nyrt. Oczyszczanie immunoglobuliny z zastosowaniem etapów wstępnego oczyszczania
WO2016096071A1 (en) * 2014-12-15 2016-06-23 Merck Patent Gmbh Target molecule capture from crude solutions
SG11201700841QA (en) 2014-12-19 2017-03-30 Chugai Pharmaceutical Co Ltd Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
MY183415A (en) 2014-12-19 2021-02-18 Chugai Pharmaceutical Co Ltd Anti-c5 antibodies and methods of use
KR102605798B1 (ko) 2015-02-05 2023-11-23 추가이 세이야쿠 가부시키가이샤 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용
BR112017014067B1 (pt) 2015-02-27 2021-01-12 Chugai Seiyaku Kabushiki Kaisha usos de um anticorpo receptor de il-6 para no tratamento de doenças relacionadas a il-6
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
MX2019001448A (es) 2016-08-05 2019-09-13 Chugai Pharmaceutical Co Ltd Composicion para profilaxis o tratamiento de enfermedades relacionadas con interleucina 8 (il-8).
JP7191833B2 (ja) 2017-01-30 2022-12-19 中外製薬株式会社 抗スクレロスチン抗体およびその使用
JP7185884B2 (ja) 2017-05-02 2022-12-08 国立研究開発法人国立精神・神経医療研究センター Ｉｌ－６及び好中球の関連する疾患の治療効果の予測及び判定方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
JP4216950B2 (ja) * 1998-09-01 2009-01-28 株式会社林原生物化学研究所 インターロイキン−１８結合蛋白質
EP1110969A4 (en) 1998-09-01 2002-01-09 Hayashibara Biochem Lab INTERLEUKIN 18 BINDING PROTEIN
US20020052475A1 (en) * 2000-07-20 2002-05-02 Schering Ag High affinity soluble interleukin-18 receptor
CN100503829C (zh) * 2001-03-08 2009-06-24 阿雷斯贸易股份有限公司 白细胞介素-18突变体、其制品及应用
YU103003A (sh) * 2001-06-26 2006-05-25 Abgenix Inc. Antitela za opgl
EP1495055B1 (en) * 2002-04-18 2013-08-14 Genencor International, Inc. Production of functional antibodies in filamentous fungi
SI1601776T1 (sl) 2003-03-11 2008-10-31 Serono Lab Ekspresijski vektorji, ki vsebujejo mcmv ie2 promotor
CA2524403C (en) 2003-05-13 2013-07-09 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
ES2354160T3 (es) 2003-10-21 2011-03-10 Merck Serono Sa Secuencia de adn mínima que actúa como un aislante de cromatina, y su uso en la expresión de proteínas.
ME01218B (me) 2004-03-01 2013-06-20 Ares Trading Sa Upotreba podloge za ćelijsku strukturu bez sadrzaja seruma za produkciju il-18bp u ćelijama sisara
ATE408616T1 (de) 2004-06-29 2008-10-15 Ares Trading Sa Verfahren zur aufreinigung von il-18-bindendem protein
US7691611B2 (en) 2005-06-03 2010-04-06 Ares Trading S.A. Production of recombinant IL-18 binding protein
JP5091127B2 (ja) 2005-06-10 2012-12-05 アレス トレーディング ソシエテ アノニム Ｉｌ−１８結合タンパク質の精製のための方法

Also Published As

Publication number Publication date
ES2285543T3 (es) 2007-11-16
IL175431A0 (en) 2006-09-05
JP2007533651A (ja) 2007-11-22
NO20062545L (no) 2006-08-03
AU2004291341B2 (en) 2010-08-05
HRP20070196T3 (en) 2007-06-30
EP1689777A1 (en) 2006-08-16
ATE360647T1 (de) 2007-05-15
NO330538B1 (no) 2011-05-09
IL175431A (en) 2011-02-28
JP4741504B2 (ja) 2011-08-03
CA2544146C (en) 2012-10-02
US7820800B2 (en) 2010-10-26
EP1689777B1 (en) 2007-04-25
SI1689777T1 (sl) 2007-08-31
DE602004006157T2 (de) 2008-01-03
ME01198B (me) 2013-03-20
US20070037734A1 (en) 2007-02-15
DE602004006157D1 (de) 2007-06-06
AU2004291341A1 (en) 2005-06-02
CA2544146A1 (en) 2005-06-02
CY1106683T1 (el) 2012-05-23
PL1689777T3 (pl) 2007-09-28
DK1689777T3 (da) 2007-06-11
WO2005049649A1 (en) 2005-06-02
PT1689777E (pt) 2007-05-31

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