SI1689777T1 - Postopek za äśiĺ äśenje il-18 vezavnega proteina - Google Patents

Postopek za äśiĺ äśenje il-18 vezavnega proteina

Info

Publication number
SI1689777T1
SI1689777T1 SI200430322T SI200430322T SI1689777T1 SI 1689777 T1 SI1689777 T1 SI 1689777T1 SI 200430322 T SI200430322 T SI 200430322T SI 200430322 T SI200430322 T SI 200430322T SI 1689777 T1 SI1689777 T1 SI 1689777T1
Authority
SI
Slovenia
Prior art keywords
purification
binding protein
fluid
relates
hydrophobic charge
Prior art date
Application number
SI200430322T
Other languages
English (en)
Inventor
Mara Rossi
Thierry Ziegler
Laure Valognes
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of SI1689777T1 publication Critical patent/SI1689777T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
SI200430322T 2003-11-05 2004-11-04 Postopek za äśiĺ äśenje il-18 vezavnega proteina SI1689777T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51744703P 2003-11-05 2003-11-05
EP03104092 2003-11-05
EP04798163A EP1689777B1 (en) 2003-11-05 2004-11-04 Process for the purification of il-18 binding protein
PCT/EP2004/052807 WO2005049649A1 (en) 2003-11-05 2004-11-04 Process for the purification of il-18 binding protein

Publications (1)

Publication Number Publication Date
SI1689777T1 true SI1689777T1 (sl) 2007-08-31

Family

ID=34924126

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200430322T SI1689777T1 (sl) 2003-11-05 2004-11-04 Postopek za äśiĺ äśenje il-18 vezavnega proteina

Country Status (19)

Country Link
US (1) US7820800B2 (sl)
EP (1) EP1689777B1 (sl)
JP (1) JP4741504B2 (sl)
AT (1) ATE360647T1 (sl)
AU (1) AU2004291341B2 (sl)
CA (1) CA2544146C (sl)
CY (1) CY1106683T1 (sl)
DE (1) DE602004006157T2 (sl)
DK (1) DK1689777T3 (sl)
ES (1) ES2285543T3 (sl)
HR (1) HRP20070196T3 (sl)
IL (1) IL175431A (sl)
ME (1) ME01198B (sl)
NO (1) NO330538B1 (sl)
PL (1) PL1689777T3 (sl)
PT (1) PT1689777E (sl)
RS (1) RS50516B (sl)
SI (1) SI1689777T1 (sl)
WO (1) WO2005049649A1 (sl)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2309508T3 (es) 2003-03-11 2008-12-16 Laboratoires Serono Sa Vectores de expresion que comprenden el promotor de mcmv-ie2.
PT1622939E (pt) * 2003-05-13 2012-03-28 Merck Serono Sa Variantes ativas da proteína de ligação à il-18 e suas utilizações médicas
CA2541523A1 (en) * 2003-10-21 2005-05-06 Applied Research Systems Ars Holding N.V. Minimal dna sequence acting as a chromatin insulator and its use in protein expression
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
AU2005217154B2 (en) * 2004-03-01 2010-02-18 Ares Trading S.A. Use of a serum-free cell culture medium for the production of IL-18BP in mammalian cells
AU2005259269B2 (en) * 2004-06-29 2010-12-09 Ares Trading S.A. Process for the purification of IL-18 binding protein
WO2006110277A1 (en) 2005-04-11 2006-10-19 Medarex, Inc. Protein purification using hcic amd ion exchange chromatography
DK1885753T3 (da) * 2005-06-03 2011-10-03 Ares Trading Sa Fremstilling af rekombinant II-18-proteiner
RS52273B (en) * 2005-06-10 2012-10-31 Ares Trading S.A. PROCESS FOR PURIFICATION OF IL-18 BINDING PROTEIN
CN101874042B9 (zh) 2007-09-26 2019-01-01 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
AU2009204998B2 (en) 2008-01-18 2014-03-27 F. Hoffmann-La Roche Ag Purification of non-glycosylated proteins
NZ602884A (en) 2008-04-11 2014-08-29 Chugai Pharmaceutical Co Ltd Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
WO2011156369A2 (en) * 2010-06-07 2011-12-15 Dr. Reddy's Laboratories Ltd. Purification of modified cytokines
KR102385507B1 (ko) 2010-11-30 2022-04-12 추가이 세이야쿠 가부시키가이샤 복수 분자의 항원에 반복해서 결합하는 항원 결합 분자
US20140093496A1 (en) 2011-02-25 2014-04-03 Chugai Seiyaku Kabushiki Kaisha Fc-gamma-RIIb-SPECIFIC Fc ANTIBODY
JP6147726B2 (ja) 2011-03-29 2017-06-14 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ タンパク質精製のためのバッファー系
TW201817745A (zh) 2011-09-30 2018-05-16 日商中外製藥股份有限公司 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子
WO2013047748A1 (ja) 2011-09-30 2013-04-04 中外製薬株式会社 複数の生理活性を有する抗原の消失を促進する抗原結合分子
KR20140100532A (ko) 2011-11-30 2014-08-14 추가이 세이야쿠 가부시키가이샤 면역 복합체를 형성하는 세포내로의 운반체（캐리어）를 포함하는 의약
EP3783017A1 (en) 2013-04-02 2021-02-24 Chugai Seiyaku Kabushiki Kaisha Fc region variant
JP6293907B2 (ja) * 2014-03-10 2018-03-14 リヒター ゲデオン エヌワイアールティー． プレクリーニング工程を用いた免疫グロブリンの精製
WO2016096071A1 (en) * 2014-12-15 2016-06-23 Merck Patent Gmbh Target molecule capture from crude solutions
SG11201700841QA (en) 2014-12-19 2017-03-30 Chugai Pharmaceutical Co Ltd Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
AU2015365167B2 (en) 2014-12-19 2021-07-29 Chugai Seiyaku Kabushiki Kaisha Anti-C5 antibodies and methods of use
CN114773469A (zh) 2015-02-05 2022-07-22 中外制药株式会社 包含离子浓度依赖性的抗原结合结构域的抗体，fc区变体，il-8-结合抗体及其应用
JP6130983B2 (ja) 2015-02-27 2017-05-17 中外製薬株式会社 Ｉｌ−６関連疾患治療用組成物
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
SG11201801024XA (en) 2016-08-05 2018-05-30 Chugai Pharmaceutical Co Ltd Therapeutic or preventive compositions for il-8-related diseases
WO2018139623A1 (en) 2017-01-30 2018-08-02 Chugai Seiyaku Kabushiki Kaisha Anti-sclerostin antibodies and methods of use
JP7185884B2 (ja) 2017-05-02 2022-12-08 国立研究開発法人国立精神・神経医療研究センター Ｉｌ－６及び好中球の関連する疾患の治療効果の予測及び判定方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
JP4216950B2 (ja) * 1998-09-01 2009-01-28 株式会社林原生物化学研究所 インターロイキン−１８結合蛋白質
BR9816013A (pt) * 1998-09-01 2003-01-21 Hayashibara Biochem Lab Proteìna de ligação de interleucina-18
US20020052475A1 (en) * 2000-07-20 2002-05-02 Schering Ag High affinity soluble interleukin-18 receptor
EA005769B1 (ru) * 2001-03-08 2005-06-30 Арес Трейдинг С.А. Мутанты интерлейкина-18, их продуцирование и применение
TR201809008T4 (tr) * 2001-06-26 2018-07-23 Amgen Fremont Inc Opgl ye karşi antikorlar.
US20040018573A1 (en) * 2002-04-18 2004-01-29 Power Scott D Production of functional antibodies in filamentous fungi
ES2309508T3 (es) 2003-03-11 2008-12-16 Laboratoires Serono Sa Vectores de expresion que comprenden el promotor de mcmv-ie2.
PT1622939E (pt) 2003-05-13 2012-03-28 Merck Serono Sa Variantes ativas da proteína de ligação à il-18 e suas utilizações médicas
CA2541523A1 (en) 2003-10-21 2005-05-06 Applied Research Systems Ars Holding N.V. Minimal dna sequence acting as a chromatin insulator and its use in protein expression
AU2005217154B2 (en) 2004-03-01 2010-02-18 Ares Trading S.A. Use of a serum-free cell culture medium for the production of IL-18BP in mammalian cells
AU2005259269B2 (en) 2004-06-29 2010-12-09 Ares Trading S.A. Process for the purification of IL-18 binding protein
DK1885753T3 (da) 2005-06-03 2011-10-03 Ares Trading Sa Fremstilling af rekombinant II-18-proteiner
RS52273B (en) 2005-06-10 2012-10-31 Ares Trading S.A. PROCESS FOR PURIFICATION OF IL-18 BINDING PROTEIN

Also Published As

Publication number Publication date
IL175431A0 (en) 2006-09-05
DE602004006157T2 (de) 2008-01-03
CA2544146C (en) 2012-10-02
IL175431A (en) 2011-02-28
DK1689777T3 (da) 2007-06-11
JP2007533651A (ja) 2007-11-22
HRP20070196T3 (en) 2007-06-30
WO2005049649A1 (en) 2005-06-02
AU2004291341B2 (en) 2010-08-05
AU2004291341A1 (en) 2005-06-02
US7820800B2 (en) 2010-10-26
US20070037734A1 (en) 2007-02-15
EP1689777A1 (en) 2006-08-16
EP1689777B1 (en) 2007-04-25
CY1106683T1 (el) 2012-05-23
ATE360647T1 (de) 2007-05-15
JP4741504B2 (ja) 2011-08-03
DE602004006157D1 (de) 2007-06-06
RS50516B (sr) 2010-05-07
ES2285543T3 (es) 2007-11-16
PL1689777T3 (pl) 2007-09-28
CA2544146A1 (en) 2005-06-02
ME01198B (me) 2013-03-20
PT1689777E (pt) 2007-05-31
NO330538B1 (no) 2011-05-09
NO20062545L (no) 2006-08-03

Similar Documents

Publication Publication Date Title
IL175431A0 (en) Purification of il-18 binding protein
IL179997A0 (en) Process for purification of il-18bp
IL187935A0 (en) Process for the purification of il-18 binding protein
WO2003102132A3 (en) Non-affinity purification of proteins
ZA200507997B (en) Purification of fluid compounds utilizing a distillation-membrane separation process
IL174951A0 (en) Method for the production of amino crotonyl compounds
TW200508201A (en) Novel process for the preparation of roflumilast
AU2003286588A8 (en) Methods for synthesizing complementary dna
EP1612274A4 (en) PROCESS FOR PURIFYING DIFRUCTOSE-DIANHYDRIDE III
ZA200308460B (en) Purification of metals from mixtures thereof.
PT2258847T (pt) Outras novas formas de moléculas de arn de interferência
AU2003258208A8 (en) Multi-dimensional chromatography system for proteomics
NO20051938L (no) Promoter til IL-18BP, dens fremstilling og anvendelse
IL173709A0 (en) Process for the purification of terbinafine
EG23264A (en) Monomethyl paraffin adsorptive separation process.
HK1082751A1 (en) Process for the purification of tnf-binding protins using imac
IL175765A0 (en) Process for the purification of gabapentin
IL172152A0 (en) Process for the purification of gabapentin
WO2002072760A3 (en) Pcra helicase inhibitors
ZA200401867B (en) Purification of chemical compounds.
GB0221469D0 (en) Multi-dimensional chromatography system for proteomics
AU2002300761A1 (en) Process For Purifying Starches