DK168451B1 - Fremgangsmåde til fremstilling af cephalosporin C og anvendelse af nærmere angivne phosphorforbindelser til reduktion af dannelsen af desacetylcephalosporin C ved dyrkning af en cephalosporin C-producerende mikroorganisme, der også producerer desacetylcephalosporin C. - Google Patents

Fremgangsmåde til fremstilling af cephalosporin C og anvendelse af nærmere angivne phosphorforbindelser til reduktion af dannelsen af desacetylcephalosporin C ved dyrkning af en cephalosporin C-producerende mikroorganisme, der også producerer desacetylcephalosporin C. Download PDF

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Publication number
DK168451B1
DK168451B1 DK139484A DK139484A DK168451B1 DK 168451 B1 DK168451 B1 DK 168451B1 DK 139484 A DK139484 A DK 139484A DK 139484 A DK139484 A DK 139484A DK 168451 B1 DK168451 B1 DK 168451B1
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DK
Denmark
Prior art keywords
cephalosporin
phenyl
hydrogen
phosphorus compound
alkyl
Prior art date
Application number
DK139484A
Other languages
Danish (da)
English (en)
Other versions
DK139484A (da
DK139484D0 (da
Inventor
David Anthony Lowe
Guna Romancik
Leonardo M Cappelletti
Richard Paul Elander
Original Assignee
Squibb Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb Bristol Myers Co filed Critical Squibb Bristol Myers Co
Publication of DK139484D0 publication Critical patent/DK139484D0/da
Publication of DK139484A publication Critical patent/DK139484A/da
Application granted granted Critical
Publication of DK168451B1 publication Critical patent/DK168451B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK139484A 1983-03-07 1984-02-29 Fremgangsmåde til fremstilling af cephalosporin C og anvendelse af nærmere angivne phosphorforbindelser til reduktion af dannelsen af desacetylcephalosporin C ved dyrkning af en cephalosporin C-producerende mikroorganisme, der også producerer desacetylcephalosporin C. DK168451B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47244483 1983-03-07
US06/472,444 US4520101A (en) 1983-03-07 1983-03-07 Production of cephalosporin C

Publications (3)

Publication Number Publication Date
DK139484D0 DK139484D0 (da) 1984-02-29
DK139484A DK139484A (da) 1984-09-08
DK168451B1 true DK168451B1 (da) 1994-03-28

Family

ID=23875534

Family Applications (1)

Application Number Title Priority Date Filing Date
DK139484A DK168451B1 (da) 1983-03-07 1984-02-29 Fremgangsmåde til fremstilling af cephalosporin C og anvendelse af nærmere angivne phosphorforbindelser til reduktion af dannelsen af desacetylcephalosporin C ved dyrkning af en cephalosporin C-producerende mikroorganisme, der også producerer desacetylcephalosporin C.

Country Status (27)

Country Link
US (1) US4520101A (zh)
JP (1) JPH069517B2 (zh)
KR (1) KR910002861B1 (zh)
AT (1) AT381723B (zh)
AU (1) AU567142B2 (zh)
BE (1) BE899086A (zh)
CA (1) CA1209072A (zh)
CH (1) CH661284A5 (zh)
CY (1) CY1467A (zh)
DE (1) DE3408194A1 (zh)
DK (1) DK168451B1 (zh)
ES (1) ES530294A0 (zh)
FI (1) FI78733C (zh)
FR (1) FR2545502B1 (zh)
GB (1) GB2136000B (zh)
GR (1) GR81804B (zh)
HK (1) HK16189A (zh)
IE (1) IE57096B1 (zh)
IT (1) IT1175945B (zh)
KE (1) KE3849A (zh)
LU (1) LU85240A1 (zh)
MY (1) MY8800129A (zh)
NL (1) NL194830C (zh)
PT (1) PT78205B (zh)
SE (1) SE461470B (zh)
SG (1) SG79688G (zh)
ZA (1) ZA841602B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9689021B2 (en) * 2011-10-14 2017-06-27 Université de Liège Method for measuring beta-lactam antibiotics

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB820422A (en) * 1957-01-30 1959-09-23 Ici Ltd Production of cephalosporin by fermentation
US3151240A (en) * 1960-09-27 1964-09-29 Bendix Corp Carrier signal attenuation as a function of two variables
FR1363594A (fr) * 1962-07-02 1964-06-12 Merck & Co Inc Procédé de production de céphalosporine c par fermentation
GB975394A (en) * 1962-07-25 1964-11-18 Farmaceutici Italia Cephalosporin c
GB1109362A (en) * 1964-04-10 1968-04-10 Nat Res Dev Improvements in fermentation processes for the production of antibiotics from emericellopsis-cephalosporium fungi
US3573296A (en) * 1968-07-01 1971-03-30 Bristol Myers Co Process for the preparation of 7-aminocephalosporanic acid
CH553850A (de) * 1970-01-21 1974-09-13 Ciba Geigy Ag Verfahren zur darstellung von fuer die gesteuerte biosynthese von cephalosporin c, geeigneten mangel-mutanten und deren verwendung zur gesteuerten biosynthese von cephalosporin c.
GB1400433A (en) * 1971-08-13 1975-07-16 Alfa Farmaceutici Spa Production of cephalosporin c
JPS5431077B2 (zh) * 1971-11-15 1979-10-04
US3830809A (en) * 1972-08-25 1974-08-20 Bristol Myers Co Bis-dicyclohexylamine n-carbisobutoxycephalosporin c
US4059573A (en) * 1973-08-01 1977-11-22 Glaxo Laboratories Limited Extraction of N-blocked amino acids from aqueous media
DK385974A (zh) * 1973-08-17 1975-04-28 Ciba Geigy Ag
JPS577719B2 (zh) * 1973-09-28 1982-02-12
JPS577720B2 (zh) * 1973-10-01 1982-02-12
US3932392A (en) * 1974-01-14 1976-01-13 Bristol-Myers Company Process for the preparation of 7-aminocephalosporanic acids
IT1042829B (it) * 1975-09-24 1980-01-30 Lorenzini Sas Inst Biochim Procedimento per la produzione di cefalosporina c
GB1597856A (en) * 1977-03-07 1981-09-16 Massachusetts Inst Technology Production of cephalosporin antibiotics
US4178210A (en) * 1977-03-07 1979-12-11 Massachusetts Institute Of Technology Accellular synthesis of cephalosporins
JPS54163880A (en) * 1978-04-26 1979-12-26 Glaxo Group Ltd Improvement in cephalosporin production

Also Published As

Publication number Publication date
CY1467A (en) 1989-07-21
ES8505211A1 (es) 1985-05-16
JPH069517B2 (ja) 1994-02-09
SE461470B (sv) 1990-02-19
NL194830C (nl) 2003-04-03
GR81804B (zh) 1984-12-12
CA1209072A (en) 1986-08-05
HK16189A (en) 1989-03-03
SE8401235L (sv) 1984-09-08
ES530294A0 (es) 1985-05-16
DE3408194A1 (de) 1985-04-18
BE899086A (fr) 1984-09-06
JPS59173097A (ja) 1984-09-29
FI840838A0 (fi) 1984-03-02
AU2447884A (en) 1984-09-13
GB8405879D0 (en) 1984-04-11
DE3408194C2 (zh) 1991-06-27
FI78733B (fi) 1989-05-31
ZA841602B (en) 1984-10-31
LU85240A1 (fr) 1984-11-14
IE57096B1 (en) 1992-04-22
ATA74384A (de) 1986-04-15
PT78205A (en) 1984-04-01
KR840008167A (ko) 1984-12-13
PT78205B (en) 1986-08-05
US4520101A (en) 1985-05-28
SE8401235D0 (sv) 1984-03-06
SG79688G (en) 1989-03-23
NL8400691A (nl) 1984-10-01
IE840536L (en) 1984-09-07
DK139484A (da) 1984-09-08
FR2545502A1 (fr) 1984-11-09
IT8419892A0 (it) 1984-03-02
FI78733C (fi) 1989-09-11
KR910002861B1 (ko) 1991-05-06
FR2545502B1 (fr) 1986-10-17
GB2136000B (en) 1986-09-10
FI840838A (fi) 1984-09-08
IT1175945B (it) 1987-08-12
AU567142B2 (en) 1987-11-12
NL194830B (nl) 2002-12-02
CH661284A5 (de) 1987-07-15
AT381723B (de) 1986-11-25
GB2136000A (en) 1984-09-12
MY8800129A (en) 1988-12-31
KE3849A (en) 1989-03-31
DK139484D0 (da) 1984-02-29

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B1 Patent granted (law 1993)
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