DK168334B1 - 4-substituerede catechol-derivater, fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af farmaceutiske præparater og farmaceutiske præparater indeholdende sådanne derivater - Google Patents

4-substituerede catechol-derivater, fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af farmaceutiske præparater og farmaceutiske præparater indeholdende sådanne derivater Download PDF

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Publication number
DK168334B1
DK168334B1 DK457386A DK457386A DK168334B1 DK 168334 B1 DK168334 B1 DK 168334B1 DK 457386 A DK457386 A DK 457386A DK 457386 A DK457386 A DK 457386A DK 168334 B1 DK168334 B1 DK 168334B1
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DK
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Prior art keywords
preparation
derivatives
substituted catechol
compound
tosylate
Prior art date
Application number
DK457386A
Other languages
Danish (da)
English (en)
Other versions
DK457386A (da
DK457386D0 (da
Inventor
Michel Follet
Marc Bonato
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of DK457386D0 publication Critical patent/DK457386D0/da
Publication of DK457386A publication Critical patent/DK457386A/da
Application granted granted Critical
Publication of DK168334B1 publication Critical patent/DK168334B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Steroid Compounds (AREA)
DK457386A 1985-09-26 1986-09-25 4-substituerede catechol-derivater, fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af farmaceutiske præparater og farmaceutiske præparater indeholdende sådanne derivater DK168334B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8523776 1985-09-26
GB858523776A GB8523776D0 (en) 1985-09-26 1985-09-26 Catechol derivatives

Publications (3)

Publication Number Publication Date
DK457386D0 DK457386D0 (da) 1986-09-25
DK457386A DK457386A (da) 1987-03-27
DK168334B1 true DK168334B1 (da) 1994-03-14

Family

ID=10585770

Family Applications (2)

Application Number Title Priority Date Filing Date
DK457386A DK168334B1 (da) 1985-09-26 1986-09-25 4-substituerede catechol-derivater, fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af farmaceutiske præparater og farmaceutiske præparater indeholdende sådanne derivater
DK457486A DK165115C (da) 1985-09-26 1986-09-25 Bicycliske catechol-derivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne derivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK457486A DK165115C (da) 1985-09-26 1986-09-25 Bicycliske catechol-derivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne derivater

Country Status (28)

Country Link
US (2) US4699919A (fr)
JP (2) JPS6284080A (fr)
AR (2) AR241702A1 (fr)
AT (2) AT402070B (fr)
BE (2) BE905433A (fr)
CA (2) CA1318686C (fr)
CH (2) CH668261A5 (fr)
DE (2) DE3632824A1 (fr)
DK (2) DK168334B1 (fr)
DZ (2) DZ990A1 (fr)
ES (2) ES2001705A6 (fr)
FI (2) FI84480C (fr)
FR (4) FR2587703B1 (fr)
GB (3) GB8523776D0 (fr)
HK (2) HK91289A (fr)
IE (2) IE59479B1 (fr)
IT (2) IT1235761B (fr)
LU (2) LU86591A1 (fr)
MA (2) MA20780A1 (fr)
MY (2) MY103521A (fr)
NL (2) NL189410C (fr)
NO (2) NO165238C (fr)
OA (2) OA08416A (fr)
PT (2) PT83437B (fr)
SE (2) SE467053B (fr)
SG (1) SG65889G (fr)
TN (2) TNSN86134A1 (fr)
ZA (2) ZA866905B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927629A (en) * 1987-12-17 1990-05-22 Huntington Medical Research Institutes Relaxation of smooth vascular muscle
EP1044002A4 (fr) * 1997-11-07 2003-05-02 Univ Johns Hopkins Procedes de traitement de troubles de la contractilite cardiaque
KR20110033304A (ko) * 2008-07-23 2011-03-30 메사추세츠 인스티튜트 오브 테크놀로지 Ｄｎａ 손상에 대해 보호하고 신경세포 생존을 증가시키는 히스톤 디아세틸라제 1 (ｈｄａｃ1)의 활성화
RS58438B1 (sr) 2011-07-22 2019-04-30 Massachusetts Inst Technology Aktivatori klase i histonskih deacetilaza (hdacs) i njihova primena

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2549118A (en) * 1949-10-05 1951-04-17 Us Rubber Co Vulcanized rubber and method of preserving same
CH301688A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
CH301691A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
CH301687A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
US3148997A (en) * 1963-01-04 1964-09-15 Dow Chemical Co Catechol compounds in improving clays and clay-containing materials
US3282979A (en) * 1963-06-17 1966-11-01 Dow Chemical Co Phenolic thioethers
US3274257A (en) * 1963-06-17 1966-09-20 Dow Chemical Co Synthesis of (alkylthio) phenols
GB1362782A (en) * 1970-08-26 1974-08-07 Fisons Ltd Tetrazole derivatives
US3751483A (en) * 1971-10-13 1973-08-07 Crown Zellerbach Corp Phenolic thioethers and process for preparing same
GB1428110A (en) * 1972-05-30 1976-03-17 Reckitt & Colmann Prod Ltd Pharmaceutical antihypertensive and vasodilator compositions
JPS506340A (fr) * 1973-05-16 1975-01-23
DE2644591A1 (de) * 1976-10-02 1978-04-06 Bayer Ag Verfahren zur herstellung von arylsulfoniumsalzen
AU548253B2 (en) * 1981-05-11 1985-12-05 Pierre Fabre S.A. Benzoxepine derivatives and sulphur and nitrogen analogues thereof
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
JPS60260532A (ja) * 1984-06-07 1985-12-23 Yamanouchi Pharmaceut Co Ltd 新規カテコ−ル誘導体
US4785004A (en) * 1985-12-23 1988-11-15 Ciba-Geigy Corporation Aromatic thioethers

Also Published As

Publication number Publication date
IE862533L (en) 1987-03-26
IE59479B1 (en) 1994-03-09
NO170415C (no) 1992-10-14
NO165238C (no) 1991-01-16
SE8603793L (sv) 1987-03-27
NL189410B (nl) 1992-11-02
FR2587703A1 (fr) 1987-03-27
CH668261A5 (fr) 1988-12-15
IT1235761B (it) 1992-09-28
GB8623075D0 (en) 1986-10-29
ZA866906B (en) 1987-04-29
NO863835D0 (no) 1986-09-25
NO165238B (no) 1990-10-08
NO863834L (no) 1987-03-27
FR2587698B1 (fr) 1989-04-28
GB2189782A (en) 1987-11-04
ZA866905B (en) 1987-04-29
DZ991A1 (fr) 2004-09-13
NL8602383A (nl) 1987-04-16
US4699919A (en) 1987-10-13
GB2189782B (en) 1989-04-12
DK457386A (da) 1987-03-27
IT8621837A0 (it) 1986-09-26
DK457386D0 (da) 1986-09-25
LU86591A1 (fr) 1987-01-22
TNSN86134A1 (fr) 1990-01-01
SE467053B (sv) 1992-05-18
DK165115C (da) 1993-03-01
DE3632824C2 (fr) 1992-04-30
ES2001705A6 (es) 1988-06-01
GB2181431B (en) 1989-09-20
JPS6284055A (ja) 1987-04-17
ATA257486A (de) 1996-06-15
FI863743A0 (fi) 1986-09-16
DE3632841A1 (de) 1987-04-02
BE905433A (fr) 1987-03-16
MA20780A1 (fr) 1987-04-01
FR2587699B1 (fr) 1988-11-10
SG65889G (en) 1990-01-26
BE905432A (fr) 1987-03-16
SE8603792D0 (sv) 1986-09-10
AR242559A1 (es) 1993-04-30
JPS6284080A (ja) 1987-04-17
DZ990A1 (fr) 2004-09-13
FR2587698A1 (fr) 1987-03-27
CA1278299C (fr) 1990-12-27
NL189334C (nl) 1993-03-16
CH668421A5 (fr) 1988-12-30
NO863835L (no) 1987-03-27
FR2587699A1 (fr) 1987-03-27
IT8621836A0 (it) 1986-09-26
IE59478B1 (en) 1994-03-09
LU86590A1 (fr) 1987-01-22
HK46190A (en) 1990-06-22
SE8603793D0 (sv) 1986-09-10
DK165115B (da) 1992-10-12
GB8623074D0 (en) 1986-10-29
NO170415B (no) 1992-07-06
DK457486A (da) 1987-03-27
OA08417A (fr) 1988-06-30
AT396469B (de) 1993-09-27
PT83437A (en) 1986-10-01
MA20779A1 (fr) 1987-04-01
FI87646B (fi) 1992-10-30
NO863834D0 (no) 1986-09-25
MY105863A (en) 1995-02-28
IE862532L (en) 1987-03-26
PT83436A (en) 1986-10-01
DE3632841C2 (fr) 1992-06-11
ES2001440A6 (es) 1988-05-16
FR2587703B1 (fr) 1988-11-04
NL8602382A (nl) 1987-04-16
HK91289A (en) 1989-11-24
SE8603792L (sv) 1987-03-27
GB8523776D0 (en) 1985-10-30
FR2587702A1 (fr) 1987-03-27
DK457486D0 (da) 1986-09-25
PT83437B (pt) 1988-07-29
JPH0417956B2 (fr) 1992-03-26
FR2587702B1 (fr) 1988-11-04
SE464522B (sv) 1991-05-06
FI84480C (fi) 1991-12-10
NL189410C (nl) 1993-04-01
FI84480B (fi) 1991-08-30
US5013756A (en) 1991-05-07
CA1318686C (fr) 1993-06-01
JPH0482129B2 (fr) 1992-12-25
TNSN86135A1 (fr) 1990-01-01
DE3632824A1 (de) 1987-04-02
MY103521A (en) 1993-07-31
FI87646C (fi) 1993-02-10
OA08416A (fr) 1988-06-30
FI863743A (fi) 1987-03-27
FI863742A (fi) 1987-03-27
FI863742A0 (fi) 1986-09-16
GB2181431A (en) 1987-04-23
AR241702A1 (es) 1992-11-30
PT83436B (pt) 1988-07-29
ATA257386A (de) 1993-01-15
AT402070B (de) 1997-01-27
IT1235760B (it) 1992-09-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed