NL189410B - Bicyclische pyrocatecholderivaten met lipoxygenase- en cyclooexygenaseremmende werking, werkwijze voor de bereiding daarvan, alsmede therapeutische preparaten die ze bevatten. - Google Patents

Bicyclische pyrocatecholderivaten met lipoxygenase- en cyclooexygenaseremmende werking, werkwijze voor de bereiding daarvan, alsmede therapeutische preparaten die ze bevatten.

Info

Publication number
NL189410B
NL189410B NLAANVRAGE8602383,A NL8602383A NL189410B NL 189410 B NL189410 B NL 189410B NL 8602383 A NL8602383 A NL 8602383A NL 189410 B NL189410 B NL 189410B
Authority
NL
Netherlands
Prior art keywords
cyclooexygenase
lipoxygenase
bicyclic
preparation
preparations containing
Prior art date
Application number
NLAANVRAGE8602383,A
Other languages
English (en)
Other versions
NL8602383A (nl
NL189410C (nl
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of NL8602383A publication Critical patent/NL8602383A/nl
Publication of NL189410B publication Critical patent/NL189410B/nl
Application granted granted Critical
Publication of NL189410C publication Critical patent/NL189410C/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D337/00Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02Seven-membered rings
    • C07D337/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
NLAANVRAGE8602383,A 1985-09-26 1986-09-22 Bicyclische pyrocatecholderivaten met lipoxygenase- en cyclooexygenaseremmende werking, werkwijze voor de bereiding daarvan, alsmede therapeutische preparaten die ze bevatten. NL189410C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858523776A GB8523776D0 (en) 1985-09-26 1985-09-26 Catechol derivatives
GB8523776 1985-09-26

Publications (3)

Publication Number Publication Date
NL8602383A NL8602383A (nl) 1987-04-16
NL189410B true NL189410B (nl) 1992-11-02
NL189410C NL189410C (nl) 1993-04-01

Family

ID=10585770

Family Applications (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE8602382,A NL189334C (nl) 1985-09-26 1986-09-22 Therapeutisch preparaat dat catecholderivaten bevat.
NLAANVRAGE8602383,A NL189410C (nl) 1985-09-26 1986-09-22 Bicyclische pyrocatecholderivaten met lipoxygenase- en cyclooexygenaseremmende werking, werkwijze voor de bereiding daarvan, alsmede therapeutische preparaten die ze bevatten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE8602382,A NL189334C (nl) 1985-09-26 1986-09-22 Therapeutisch preparaat dat catecholderivaten bevat.

Country Status (28)

Country Link
US (2) US4699919A (nl)
JP (2) JPS6284055A (nl)
AR (2) AR242559A1 (nl)
AT (2) AT396469B (nl)
BE (2) BE905433A (nl)
CA (2) CA1318686C (nl)
CH (2) CH668261A5 (nl)
DE (2) DE3632824A1 (nl)
DK (2) DK168334B1 (nl)
DZ (2) DZ990A1 (nl)
ES (2) ES2001705A6 (nl)
FI (2) FI84480C (nl)
FR (4) FR2587698B1 (nl)
GB (3) GB8523776D0 (nl)
HK (2) HK91289A (nl)
IE (2) IE59478B1 (nl)
IT (2) IT1235761B (nl)
LU (2) LU86590A1 (nl)
MA (2) MA20780A1 (nl)
MY (2) MY103521A (nl)
NL (2) NL189334C (nl)
NO (2) NO170415C (nl)
OA (2) OA08417A (nl)
PT (2) PT83437B (nl)
SE (2) SE464522B (nl)
SG (1) SG65889G (nl)
TN (2) TNSN86135A1 (nl)
ZA (2) ZA866905B (nl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927629A (en) * 1987-12-17 1990-05-22 Huntington Medical Research Institutes Relaxation of smooth vascular muscle
AU1520699A (en) 1997-11-07 1999-05-31 Johns Hopkins University, The Methods for treatment of disorders of cardiac contractility
US20100075926A1 (en) * 2008-07-23 2010-03-25 Li-Huei Tsai Activation of histone deacetylase 1 (hdac1) protects against dna damage and increases neuronal survival
RS58438B1 (sr) 2011-07-22 2019-04-30 Massachusetts Inst Technology Aktivatori klase i histonskih deacetilaza (hdacs) i njihova primena

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2549118A (en) * 1949-10-05 1951-04-17 Us Rubber Co Vulcanized rubber and method of preserving same
CH301688A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
CH301687A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
CH301691A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
US3148997A (en) * 1963-01-04 1964-09-15 Dow Chemical Co Catechol compounds in improving clays and clay-containing materials
US3274257A (en) * 1963-06-17 1966-09-20 Dow Chemical Co Synthesis of (alkylthio) phenols
US3282979A (en) * 1963-06-17 1966-11-01 Dow Chemical Co Phenolic thioethers
GB1362782A (en) * 1970-08-26 1974-08-07 Fisons Ltd Tetrazole derivatives
US3751483A (en) * 1971-10-13 1973-08-07 Crown Zellerbach Corp Phenolic thioethers and process for preparing same
GB1428110A (en) * 1972-05-30 1976-03-17 Reckitt & Colmann Prod Ltd Pharmaceutical antihypertensive and vasodilator compositions
JPS506340A (nl) * 1973-05-16 1975-01-23
DE2644591A1 (de) * 1976-10-02 1978-04-06 Bayer Ag Verfahren zur herstellung von arylsulfoniumsalzen
AU548253B2 (en) * 1981-05-11 1985-12-05 Pierre Fabre S.A. Benzoxepine derivatives and sulphur and nitrogen analogues thereof
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
JPS60260532A (ja) * 1984-06-07 1985-12-23 Yamanouchi Pharmaceut Co Ltd 新規カテコ−ル誘導体
US4785004A (en) * 1985-12-23 1988-11-15 Ciba-Geigy Corporation Aromatic thioethers

Also Published As

Publication number Publication date
HK91289A (en) 1989-11-24
AT402070B (de) 1997-01-27
DE3632824A1 (de) 1987-04-02
FI84480B (fi) 1991-08-30
FI863742A0 (fi) 1986-09-16
PT83437B (pt) 1988-07-29
ES2001440A6 (es) 1988-05-16
AR241702A1 (es) 1992-11-30
IE59479B1 (en) 1994-03-09
NL8602382A (nl) 1987-04-16
NO863834L (no) 1987-03-27
IE862532L (en) 1987-03-26
LU86590A1 (fr) 1987-01-22
SE8603792L (sv) 1987-03-27
DE3632824C2 (nl) 1992-04-30
FR2587699B1 (fr) 1988-11-10
ES2001705A6 (es) 1988-06-01
FR2587703A1 (fr) 1987-03-27
PT83436A (en) 1986-10-01
FR2587702B1 (fr) 1988-11-04
GB8523776D0 (en) 1985-10-30
FI87646B (fi) 1992-10-30
NO165238C (no) 1991-01-16
GB8623074D0 (en) 1986-10-29
FR2587699A1 (fr) 1987-03-27
FI84480C (fi) 1991-12-10
JPS6284055A (ja) 1987-04-17
OA08417A (fr) 1988-06-30
IE59478B1 (en) 1994-03-09
NO170415C (no) 1992-10-14
NL189334C (nl) 1993-03-16
ATA257386A (de) 1993-01-15
MA20779A1 (fr) 1987-04-01
NO165238B (no) 1990-10-08
NL8602383A (nl) 1987-04-16
MY105863A (en) 1995-02-28
FI863743A0 (fi) 1986-09-16
FR2587703B1 (fr) 1988-11-04
CH668261A5 (fr) 1988-12-15
BE905433A (fr) 1987-03-16
JPS6284080A (ja) 1987-04-17
FI87646C (fi) 1993-02-10
JPH0482129B2 (nl) 1992-12-25
TNSN86135A1 (fr) 1990-01-01
MA20780A1 (fr) 1987-04-01
FI863742A (fi) 1987-03-27
GB2181431B (en) 1989-09-20
DK457486D0 (da) 1986-09-25
FR2587698A1 (fr) 1987-03-27
TNSN86134A1 (fr) 1990-01-01
CA1318686C (en) 1993-06-01
PT83436B (pt) 1988-07-29
US5013756A (en) 1991-05-07
ATA257486A (de) 1996-06-15
NO863835D0 (no) 1986-09-25
IT1235760B (it) 1992-09-28
ZA866905B (en) 1987-04-29
DK168334B1 (da) 1994-03-14
CH668421A5 (fr) 1988-12-30
PT83437A (en) 1986-10-01
AT396469B (de) 1993-09-27
DK165115B (da) 1992-10-12
GB8623075D0 (en) 1986-10-29
LU86591A1 (fr) 1987-01-22
SE8603792D0 (sv) 1986-09-10
HK46190A (en) 1990-06-22
SE467053B (sv) 1992-05-18
GB2189782A (en) 1987-11-04
IT8621836A0 (it) 1986-09-26
NO863835L (no) 1987-03-27
GB2189782B (en) 1989-04-12
FR2587702A1 (fr) 1987-03-27
NL189410C (nl) 1993-04-01
ZA866906B (en) 1987-04-29
US4699919A (en) 1987-10-13
NO863834D0 (no) 1986-09-25
DZ990A1 (fr) 2004-09-13
IT8621837A0 (it) 1986-09-26
GB2181431A (en) 1987-04-23
DK457486A (da) 1987-03-27
DE3632841C2 (nl) 1992-06-11
MY103521A (en) 1993-07-31
DK457386A (da) 1987-03-27
FI863743A (fi) 1987-03-27
DK165115C (da) 1993-03-01
CA1278299C (en) 1990-12-27
SE464522B (sv) 1991-05-06
OA08416A (fr) 1988-06-30
DZ991A1 (fr) 2004-09-13
SE8603793D0 (sv) 1986-09-10
AR242559A1 (es) 1993-04-30
JPH0417956B2 (nl) 1992-03-26
BE905432A (fr) 1987-03-16
IT1235761B (it) 1992-09-28
FR2587698B1 (fr) 1989-04-28
IE862533L (en) 1987-03-26
NO170415B (no) 1992-07-06
DK457386D0 (da) 1986-09-25
SG65889G (en) 1990-01-26
SE8603793L (sv) 1987-03-27
DE3632841A1 (de) 1987-04-02

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Effective date: 19990401