DK1479385T3 - Anvendelse af cyclooxygenase-2 inhibitorer til behandling og forebyggelse af neoplasi - Google Patents

Anvendelse af cyclooxygenase-2 inhibitorer til behandling og forebyggelse af neoplasi

Info

Publication number
DK1479385T3
DK1479385T3 DK04011516T DK04011516T DK1479385T3 DK 1479385 T3 DK1479385 T3 DK 1479385T3 DK 04011516 T DK04011516 T DK 04011516T DK 04011516 T DK04011516 T DK 04011516T DK 1479385 T3 DK1479385 T3 DK 1479385T3
Authority
DK
Denmark
Prior art keywords
neoplasia
treatment
cyclooxygenase
inhibitors
prevention
Prior art date
Application number
DK04011516T
Other languages
English (en)
Inventor
Karen Seibert
Jaime Masferrer
Gary B Gordon
Original Assignee
Searle Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21843754&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1479385(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Searle Llc filed Critical Searle Llc
Application granted granted Critical
Publication of DK1479385T3 publication Critical patent/DK1479385T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK04011516T 1996-10-15 1997-10-14 Anvendelse af cyclooxygenase-2 inhibitorer til behandling og forebyggelse af neoplasi DK1479385T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2849496P 1996-10-15 1996-10-15
PCT/US1997/018670 WO1998016227A1 (en) 1996-10-15 1997-10-14 Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia

Publications (1)

Publication Number Publication Date
DK1479385T3 true DK1479385T3 (da) 2008-08-04

Family

ID=21843754

Family Applications (2)

Application Number Title Priority Date Filing Date
DK97911746T DK0932402T3 (da) 1996-10-15 1997-10-14 Metode til anvendelse af cyclooxygenase-2-inhibitorer ved behandling og forebyggelse af neoplasi
DK04011516T DK1479385T3 (da) 1996-10-15 1997-10-14 Anvendelse af cyclooxygenase-2 inhibitorer til behandling og forebyggelse af neoplasi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK97911746T DK0932402T3 (da) 1996-10-15 1997-10-14 Metode til anvendelse af cyclooxygenase-2-inhibitorer ved behandling og forebyggelse af neoplasi

Country Status (25)

Country Link
EP (3) EP1479385B1 (da)
JP (1) JP2001503395A (da)
KR (1) KR20000049138A (da)
CN (2) CN100558356C (da)
AT (2) ATE399547T1 (da)
AU (1) AU742645B2 (da)
BR (1) BR9712314A (da)
CA (1) CA2267186C (da)
CZ (1) CZ298022B6 (da)
DE (2) DE69738815D1 (da)
DK (2) DK0932402T3 (da)
ES (2) ES2224222T3 (da)
HK (1) HK1025518A1 (da)
HU (1) HU227564B1 (da)
IL (3) IL154501A0 (da)
NO (1) NO326822B1 (da)
NZ (3) NZ334921A (da)
PT (2) PT932402E (da)
RO (1) RO120172B1 (da)
RU (1) RU2239429C2 (da)
SK (1) SK284788B6 (da)
TR (1) TR199900827T2 (da)
TW (1) TWI235060B (da)
UA (1) UA67732C2 (da)
WO (1) WO1998016227A1 (da)

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JP5197355B2 (ja) * 2005-03-08 2013-05-15 三井農林株式会社 ポリフェノールとコキシブの組み合わせおよび方法
JPWO2010007943A1 (ja) * 2008-07-17 2012-01-05 旭化成ファーマ株式会社 含窒素複素環化合物
JP2012500630A (ja) * 2008-08-22 2012-01-12 ノバルティス アーゲー 肝毒性に関連するｈｌａ対立遺伝子を有していない患者におけるｃｏｘ−２依存性障害を治療するためのｃｏｘ−２阻害剤の使用
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Also Published As

Publication number Publication date
CA2267186C (en) 2002-05-14
PT1479385E (pt) 2008-09-02
CZ117199A3 (cs) 1999-07-14
DE69738815D1 (de) 2008-08-14
EP1977749A1 (en) 2008-10-08
NO991793L (no) 1999-04-15
CA2267186A1 (en) 1998-04-23
DE69729946D1 (de) 2004-08-26
ES2308068T3 (es) 2008-12-01
NZ509755A (en) 2002-09-27
CN1244122A (zh) 2000-02-09
UA67732C2 (uk) 2004-07-15
NO326822B1 (no) 2009-02-23
BR9712314A (pt) 1999-08-31
HUP9904221A3 (en) 2000-12-28
HU227564B1 (en) 2011-08-29
CN100558356C (zh) 2009-11-11
WO1998016227A1 (en) 1998-04-23
TR199900827T2 (xx) 1999-07-21
NO991793D0 (no) 1999-04-15
AU4904897A (en) 1998-05-11
IL165816A0 (en) 2006-01-15
RO120172B1 (ro) 2005-10-28
HK1025518A1 (en) 2000-11-17
EP1479385A1 (en) 2004-11-24
DK0932402T3 (da) 2004-11-08
IL128568A0 (en) 2000-01-31
PT932402E (pt) 2004-11-30
SK284788B6 (sk) 2005-11-03
CN1332661C (zh) 2007-08-22
AU742645B2 (en) 2002-01-10
TWI235060B (en) 2005-07-01
RU2239429C2 (ru) 2004-11-10
ATE271385T1 (de) 2004-08-15
NZ506515A (en) 2002-05-31
CN1660083A (zh) 2005-08-31
DE69729946T2 (de) 2005-01-20
EP1479385B1 (en) 2008-07-02
EP0932402B1 (en) 2004-07-21
CZ298022B6 (cs) 2007-05-30
EP0932402A1 (en) 1999-08-04
HUP9904221A2 (hu) 2000-09-28
ATE399547T1 (de) 2008-07-15
SK46299A3 (en) 2000-03-13
ES2224222T3 (es) 2005-03-01
JP2001503395A (ja) 2001-03-13
NZ334921A (en) 2001-03-30
KR20000049138A (ko) 2000-07-25
IL154501A0 (en) 2003-09-17

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