DK1443912T3 - Sammensætninger med en kombination af umiddelbare og kontrollerede frisætningsegenskaber - Google Patents
Sammensætninger med en kombination af umiddelbare og kontrollerede frisætningsegenskaberInfo
- Publication number
- DK1443912T3 DK1443912T3 DK02800993T DK02800993T DK1443912T3 DK 1443912 T3 DK1443912 T3 DK 1443912T3 DK 02800993 T DK02800993 T DK 02800993T DK 02800993 T DK02800993 T DK 02800993T DK 1443912 T3 DK1443912 T3 DK 1443912T3
- Authority
- DK
- Denmark
- Prior art keywords
- compositions
- combination
- controlled release
- immediate
- release properties
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32840501P | 2001-10-12 | 2001-10-12 | |
| PCT/US2002/032314 WO2003030872A2 (en) | 2001-10-12 | 2002-10-11 | Compositions having a combination of particles for immediate release and for controlled release |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1443912T3 true DK1443912T3 (da) | 2008-01-21 |
Family
ID=23280838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02800993T DK1443912T3 (da) | 2001-10-12 | 2002-10-11 | Sammensætninger med en kombination af umiddelbare og kontrollerede frisætningsegenskaber |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6908626B2 (enExample) |
| EP (1) | EP1443912B1 (enExample) |
| JP (5) | JP2005508939A (enExample) |
| AT (1) | ATE371442T1 (enExample) |
| AU (1) | AU2002334939A1 (enExample) |
| CA (1) | CA2463495C (enExample) |
| CY (1) | CY1107810T1 (enExample) |
| DE (1) | DE60222160T2 (enExample) |
| DK (1) | DK1443912T3 (enExample) |
| ES (1) | ES2292848T3 (enExample) |
| PT (1) | PT1443912E (enExample) |
| WO (1) | WO2003030872A2 (enExample) |
Families Citing this family (155)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080102121A1 (en) * | 1998-11-02 | 2008-05-01 | Elan Pharma International Limited | Compositions comprising nanoparticulate meloxicam and controlled release hydrocodone |
| US8551526B2 (en) * | 2000-11-03 | 2013-10-08 | Board Of Regents, The University Of Texas System | Preparation of drug particles using evaporation precipitation into aqueous solutions |
| US20080026068A1 (en) * | 2001-08-16 | 2008-01-31 | Baxter Healthcare S.A. | Pulmonary delivery of spherical insulin microparticles |
| PT1471887E (pt) | 2002-02-04 | 2010-07-16 | Elan Pharma Int Ltd | Composiães de nanopartculas com lisozima como um estabilizador superficial |
| US7803402B2 (en) * | 2002-07-06 | 2010-09-28 | Sanjeev Khandelwal | Pharmaceutical preparations |
| US20040048931A1 (en) * | 2002-07-12 | 2004-03-11 | Craig Heacock | Modafinil pharmaceutical compositions |
| DE10253623B4 (de) * | 2002-11-15 | 2006-03-09 | Justus-Liebig-Universität Giessen | Bioabbaubare kolloidale Partikel, insbesondere für pulmonale Applikationen |
| IL153098A0 (en) * | 2002-11-26 | 2003-06-24 | Chemagis Ltd | Pharmaceutical compositions containing modafinil |
| US7638138B2 (en) | 2003-02-21 | 2009-12-29 | Translational Research, Ltd. | Compositions for nasal administration of pharmaceuticals |
| US8512727B2 (en) * | 2003-03-03 | 2013-08-20 | Alkermes Pharma Ireland Limited | Nanoparticulate meloxicam formulations |
| US20100297252A1 (en) * | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
| USRE45404E1 (en) | 2003-03-27 | 2015-03-03 | Shin Nippon Biomedical Laboratories, Ltd. | Powder medicine applicator for nasal cavity |
| BE1015641A4 (fr) * | 2003-05-26 | 2005-07-05 | Mariani Jean Paul | Micronisation 70. |
| US7198653B2 (en) * | 2003-07-31 | 2007-04-03 | Delavau Llc | Calcium carbonate granulation |
| US20050058702A1 (en) * | 2003-09-17 | 2005-03-17 | Ben-Sasson Shmuel A. | Compositions capable of facilitating penetration across a biological barrier |
| CA2543458A1 (en) * | 2003-10-24 | 2005-05-12 | Josef Rettenmaier & Soehne Gmbh & Co., Kg | Process for co-spray drying agents with dry silicified mcc |
| CA2794424C (en) * | 2004-03-29 | 2019-06-04 | Wyeth Llc | Multi-vitamin and mineral nutritional supplements |
| JP4948392B2 (ja) * | 2004-03-29 | 2012-06-06 | レ ラボラトア セルビエ | 固形薬学的組成物を調製するためのプロセス |
| DE602005005033T2 (de) * | 2004-03-30 | 2009-03-19 | Smithkline Beecham Corp. | Sprühgetrocknete pharmazeutische zusammensetzungen |
| US7908041B2 (en) * | 2004-04-29 | 2011-03-15 | Munro & Associates, Inc. | Self-leveling laser horizon for navigation guidance |
| US8728525B2 (en) * | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
| SI21800A (sl) * | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
| US20060165769A1 (en) * | 2004-09-30 | 2006-07-27 | Hyatt John A | Pharmaceutical formulations containing vitamin E TPGS molecules that solubilize lipophilic drugs without significant efflux inhibition, and use of such formulations |
| WO2006041908A2 (en) * | 2004-10-08 | 2006-04-20 | Noven Pharmaceuticals, Inc. | Transdermal delivery of estradiol |
| EP2623095A1 (en) * | 2004-11-16 | 2013-08-07 | Elan Pharma International Limited | Injectable nanoparticulate olanzapine formulations |
| UA89513C2 (uk) * | 2004-12-03 | 2010-02-10 | Элан Фарма Интернешнл Лтд. | Стабільна композиція з наночастинок ралоксифену гідрохлориду |
| JP2008524239A (ja) * | 2004-12-15 | 2008-07-10 | エラン ファーマ インターナショナル リミティド | ナノ粒子のタクロリムス製剤 |
| SI2727583T1 (sl) | 2004-12-22 | 2022-01-31 | Nitto Denko Corporation | Nosilec učinkovine in komplet nosilca učinkovine za zaviranje fibroze |
| WO2006069098A1 (en) * | 2004-12-22 | 2006-06-29 | Elan Pharma International Ltd. | Nanoparticulate bicalutamide formulations |
| US20120269886A1 (en) | 2004-12-22 | 2012-10-25 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
| AU2012201630B8 (en) * | 2004-12-31 | 2014-03-06 | Iceutica Pty Ltd | NanoParticle Composition(s) and Method for Synthesis Thereof |
| CN101132770A (zh) * | 2005-01-06 | 2008-02-27 | 伊兰制药国际有限公司 | 纳米微粒坎地沙坦制剂 |
| EP2353590A1 (en) * | 2005-02-15 | 2011-08-10 | Elan Pharma International Limited | Aerosol and injectable formulations of nanoparticulate benzodiazepine |
| EP1855651A4 (en) * | 2005-03-03 | 2011-06-15 | Elan Pharma Int Ltd | NANOPARTICLE COMPOSITIONS OF HETEROCYCLIC AMID DERIVATIVES |
| US20060204588A1 (en) * | 2005-03-10 | 2006-09-14 | Elan Pharma International Limited | Formulations of a nanoparticulate finasteride, dutasteride or tamsulosin hydrochloride, and mixtures thereof |
| JP2008533157A (ja) * | 2005-03-14 | 2008-08-21 | マサチューセッツ・インスティテュート・オブ・テクノロジー | 疾患および障害の診断および処置のためのナノセル |
| US20070065374A1 (en) * | 2005-03-16 | 2007-03-22 | Elan Pharma International Limited | Nanoparticulate leukotriene receptor antagonist/corticosteroid formulations |
| WO2006102117A1 (en) * | 2005-03-17 | 2006-09-28 | Elan Pharma International Limited | Nanoparticulate biphosphonate compositions |
| MX2007011772A (es) * | 2005-03-23 | 2007-12-05 | Elan Pharma Int Ltd | Formulaciones de antihistaminico y corticosteroide de materia en nanoparticulas. |
| WO2006110809A2 (en) * | 2005-04-12 | 2006-10-19 | Elan Pharma International, Limited | Nanoparticulate lipase inhibitor formulations |
| JP2008535924A (ja) * | 2005-04-12 | 2008-09-04 | エラン ファーマ インターナショナル リミテッド | ナノ粒子キナゾリン誘導体製剤 |
| MX2007013356A (es) * | 2005-04-27 | 2008-03-26 | Baxter Int | Microparticulas modificadas en la superficie y metodos de formacion y uso de las mismas. |
| CA2605816C (en) * | 2005-04-28 | 2013-07-02 | Meiji Seika Kaisha, Ltd. | Rapidly soluble granules and method for producing the same |
| WO2006119280A2 (en) * | 2005-05-03 | 2006-11-09 | Handylab, Inc. | Lyophilized pellets |
| CA2601067A1 (en) | 2005-05-04 | 2006-11-09 | Medigene Ag | Method of administering a cationic liposomal preparation comprising paclitaxel |
| WO2006132752A1 (en) * | 2005-05-10 | 2006-12-14 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising vitamin k2 |
| CN101212954A (zh) * | 2005-05-10 | 2008-07-02 | 伊兰制药国际有限公司 | 纳米粒氯吡格雷制剂 |
| US20100028439A1 (en) * | 2005-05-23 | 2010-02-04 | Elan Pharma International Limited | Nanoparticulate stabilized anti-hypertensive compositions |
| US20070042049A1 (en) * | 2005-06-03 | 2007-02-22 | Elan Pharma International, Limited | Nanoparticulate benidipine compositions |
| EA015102B1 (ru) * | 2005-06-03 | 2011-06-30 | Элан Фарма Интернэшнл Лтд. | Препараты наночастиц мезилата иматиниба |
| WO2007053197A2 (en) * | 2005-06-03 | 2007-05-10 | Elan Pharma International, Limited | Nanoparticulate acetaminophen formulations |
| EP1954253A4 (en) | 2005-06-08 | 2011-07-27 | Elan Pharma Int Ltd | NANOTEILIC AND CONTROLLED RELEASED COMPOSITIONS WITH CEFDITORS |
| ATE446742T1 (de) * | 2005-06-09 | 2009-11-15 | Elan Pharma Int Ltd | Nanopartikuläre ebastinformulierungen |
| EP1898911A1 (en) * | 2005-06-13 | 2008-03-19 | Elan Pharma International Limited | Nanoparticulate clopidogrel and aspirin combination formulations |
| WO2006138421A2 (en) * | 2005-06-15 | 2006-12-28 | Elan Pharma International Limited | Nanoparticulate azelnidipine formulations |
| WO2007008537A2 (en) * | 2005-07-07 | 2007-01-18 | Elan Pharma International, Limited | Nanoparticulate clarithromycin formulations |
| JP5694643B2 (ja) * | 2005-08-05 | 2015-04-01 | スリーエム イノベイティブ プロパティズ カンパニー | 改善された流動性を示す組成物 |
| US20070104792A1 (en) * | 2005-09-13 | 2007-05-10 | Elan Pharma International, Limited | Nanoparticulate tadalafil formulations |
| WO2007035348A2 (en) * | 2005-09-15 | 2007-03-29 | Elan Pharma International, Limited | Nanoparticulate aripiprazole formulations |
| WO2007038675A2 (en) * | 2005-09-28 | 2007-04-05 | Oxford Pharmaceutical Services Inc. | Pharmaceutical compositions for treating or preventing migraines |
| WO2007056205A2 (en) * | 2005-11-04 | 2007-05-18 | Eastman Chemical Company | Carboxyalkylcellulose esters for administration of poorly soluble pharmaceutically active agents |
| US20070104763A1 (en) * | 2005-11-10 | 2007-05-10 | Navinta Llc | Composition of fentanyl citrate oral solid transmucosal dosage form, excipient and binding material therefore, and methods of making |
| US8532938B2 (en) | 2005-11-17 | 2013-09-10 | The Invention Science Fund I, Llc | Testing-dependent administration of a nutraceutical |
| US20070112592A1 (en) * | 2005-11-17 | 2007-05-17 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Payments in providing assistance related to health |
| US10042980B2 (en) | 2005-11-17 | 2018-08-07 | Gearbox Llc | Providing assistance related to health |
| ES2812250T3 (es) * | 2005-11-28 | 2021-03-16 | Marinus Pharmaceuticals Inc | Formulaciones de ganaxolona y procedimientos para la preparación y uso de las mismas |
| US20080082272A1 (en) * | 2005-11-30 | 2008-04-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational systems and methods related to nutraceuticals |
| US20070299693A1 (en) * | 2006-06-23 | 2007-12-27 | Searete Llc, A Limited Liability Corporation | Customized visual marking for medication labeling |
| US10296720B2 (en) | 2005-11-30 | 2019-05-21 | Gearbox Llc | Computational systems and methods related to nutraceuticals |
| US9572886B2 (en) | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
| US8367112B2 (en) * | 2006-02-28 | 2013-02-05 | Alkermes Pharma Ireland Limited | Nanoparticulate carverdilol formulations |
| CA2646156C (en) | 2006-03-22 | 2016-05-24 | Medigene Ag | Treatment of triple receptor negative breast cancer |
| US20070264350A1 (en) * | 2006-05-15 | 2007-11-15 | Ebara Corporation | Water-insoluble medicine |
| CN101495096A (zh) | 2006-05-30 | 2009-07-29 | 伊兰制药国际有限公司 | 纳米微粒泊沙康唑制剂 |
| US20070281031A1 (en) * | 2006-06-01 | 2007-12-06 | Guohan Yang | Microparticles and methods for production thereof |
| US20080086338A1 (en) * | 2006-06-23 | 2008-04-10 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Customized visual marking for medication labeling |
| US20070299695A1 (en) * | 2006-06-23 | 2007-12-27 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Customized visual marking for medication labeling |
| JP2009541360A (ja) * | 2006-06-23 | 2009-11-26 | エラン・ファルマ・インターナショナル・リミテッド | ナノ粒子状メロキシカムおよび制御放出ヒドロコドンを含む組成物 |
| US20080086339A1 (en) * | 2006-06-23 | 2008-04-10 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Customized visual marking for medication labeling |
| JP5508003B2 (ja) | 2006-06-30 | 2014-05-28 | アイスイティカ ピーティーワイ リミテッド | ナノ粒子状の形態における生物学的に活性な化合物の調製のための方法 |
| NZ573823A (en) * | 2006-06-30 | 2012-05-25 | Iceutica Pty Ltd | Methods for the preparation of biologically active compounds in nanoparticulate form |
| CA2657379A1 (en) * | 2006-07-10 | 2008-01-17 | Elan Pharma International Ltd. | Nanoparticulate sorafenib formulations |
| JP2009543803A (ja) * | 2006-07-12 | 2009-12-10 | エラン・ファルマ・インターナショナル・リミテッド | モダフィニルのナノ粒子製剤 |
| PT2049123E (pt) | 2006-08-03 | 2013-03-06 | Horizon Pharma Ag | Tratamento de doença reumatóide com glucocorticóide de libertação retardada |
| AU2007281737B2 (en) | 2006-08-04 | 2013-09-19 | Baxter Healthcare S.A. | Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes |
| MX2009003661A (es) * | 2006-10-06 | 2009-04-22 | Baxter Int | Microcapsulas que contienen microparticulas modificadas en la superficie y metodos para formar y utilizar las mismas. |
| US20080181966A1 (en) * | 2006-10-18 | 2008-07-31 | Cephalon, Inc. | Modafinil pharmaceutical compositions |
| US20100239661A1 (en) * | 2006-10-26 | 2010-09-23 | Sunilendu Bhushan Roy | Pharmaceutical compositions of ursodiol |
| WO2008066899A2 (en) * | 2006-11-28 | 2008-06-05 | Marinus Pharmaceuticals | Nanoparticulate formulations and methods for the making and use thereof |
| US9456983B1 (en) * | 2006-12-08 | 2016-10-04 | Advanced Cardiovascular Systems, Inc. | Therapeutic composition with enhanced vessel targeting |
| ES2652415T3 (es) | 2006-12-26 | 2018-02-02 | Shin Nippon Biomedical Laboratories, Ltd. | Preparación para aplicación transnasal |
| EP2120945A1 (en) * | 2007-02-28 | 2009-11-25 | Collegium Pharmaceutical, Inc. | Antihistamine combination |
| CA2678367C (en) * | 2007-03-02 | 2014-07-08 | Farnam Companies, Inc. | Sustained release compositions using wax-like materials |
| TWI407971B (zh) | 2007-03-30 | 2013-09-11 | 日東電工股份有限公司 | Cancer cells and tumor-related fibroblasts |
| US8530463B2 (en) | 2007-05-07 | 2013-09-10 | Hale Biopharma Ventures Llc | Multimodal particulate formulations |
| CA2723470C (en) * | 2007-05-07 | 2013-12-03 | Hale Biopharma Ventures, Llc | Nasal administration of benzodiazepines |
| TW200904340A (en) | 2007-05-11 | 2009-02-01 | Mannatech Inc | Processing of natural polysaccharides by selected non-pathogenic microorganisms and methods of making and using the same |
| TW200918099A (en) | 2007-09-14 | 2009-05-01 | Nitto Denko Corp | Drug carriers |
| US20110218140A1 (en) * | 2008-02-25 | 2011-09-08 | Gonsalves Kenneth E | Biodegradable therapeutic nanoparticles containing an antimicrobial agent |
| MX2010010050A (es) | 2008-03-20 | 2011-03-15 | Virun Inc Star | Emulsiones que incluyen un derivado de polietilen glicol de tocoferol. |
| EP2268265A2 (en) * | 2008-03-21 | 2011-01-05 | Elan Pharma International Limited | Compositions for site-specific delivery of imatinib and methods of use |
| US20090258865A1 (en) | 2008-03-28 | 2009-10-15 | Hale Biopharma Ventures, Llc | Administration of benzodiazepine compositions |
| US8337931B2 (en) * | 2008-06-23 | 2012-12-25 | Virun, Inc. | Compositions containing non-polar compounds |
| US20100047292A1 (en) * | 2008-08-20 | 2010-02-25 | Baxter International Inc. | Methods of processing microparticles and compositions produced thereby |
| US8323685B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| US8367427B2 (en) * | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| US8323615B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
| EP2391369A1 (en) * | 2009-01-26 | 2011-12-07 | Nitec Pharma AG | Delayed-release glucocorticoid treatment of asthma |
| NZ582836A (en) * | 2009-01-30 | 2011-06-30 | Nitec Pharma Ag | Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage |
| WO2010102065A1 (en) | 2009-03-05 | 2010-09-10 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives |
| CA2759109A1 (en) | 2009-04-24 | 2010-10-28 | Iceutica Pty Ltd | A solid dosage form of ciprofloxacin having small particle size and improved powder handling characteristics |
| NZ710384A (en) | 2009-04-24 | 2017-03-31 | Iceutica Pty Ltd | A novel formulation of indomethacin |
| CA2759123C (en) | 2009-04-24 | 2019-01-15 | Iceutica Pty Ltd | Compositions of diclofenac acid with improved dissolution |
| US9101539B2 (en) | 2009-05-15 | 2015-08-11 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal pharmaceutical compositions with improved pharmacokinetics |
| JP6072539B2 (ja) | 2009-05-27 | 2017-02-01 | アルカーメス ファーマ アイルランド リミテッド | ナノ粒子活性物質組成物におけるフレーク状凝集の軽減 |
| US20110021825A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | Process for isolating iodixanol from an aqueous solution |
| US8827946B2 (en) | 2009-07-31 | 2014-09-09 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
| EP2563164B1 (en) | 2010-03-23 | 2016-06-29 | Virun, Inc. | Nanoemulsion including sucrose fatty acid ester |
| US9012511B2 (en) | 2010-05-19 | 2015-04-21 | Alkermes Pharma Ireland Limited | Nanoparticulate cinacalcet compositions |
| FR2960775A1 (fr) * | 2010-06-07 | 2011-12-09 | Ethypharm Sa | Microgranules resistants au detournement |
| WO2011162802A1 (en) | 2010-06-21 | 2011-12-29 | Virun, Inc. | Compositions containing non-polar compounds |
| RU2596787C2 (ru) | 2010-07-09 | 2016-09-10 | БиЭйчВи ФАРМА, ИНК. | Комбинированная система доставки с немедленным/замедленным высвобождением для лекарственных средств с коротким периодом полувыведения, в том числе для ремоглифлозина |
| EP2468258A1 (en) * | 2010-12-22 | 2012-06-27 | LEK Pharmaceuticals d.d. | Process for the preparation of a pharmaceutical composition comprising a low soluble pharmaceutically active ingredient |
| US9060938B2 (en) | 2011-05-10 | 2015-06-23 | Bend Research, Inc. | Pharmaceutical compositions of active agents and cationic dextran polymer derivatives |
| PT3415139T (pt) | 2011-06-14 | 2022-06-20 | Neurelis Inc | Administração de benzodiazepina |
| BR112015009839A2 (pt) * | 2012-11-01 | 2017-07-11 | Torrent Pharmaceuticals Ltd | composição farmacêutica de tapentadol para administração parenteral |
| NZ713235A (en) | 2013-03-15 | 2019-12-20 | Glanbia Nutritionals Ireland Ltd | Product and method for improving bioavailability of therapeutic compounds |
| HUE034490T2 (en) | 2013-09-16 | 2018-02-28 | Astrazeneca Ab | Therapeutic polymer nanoparticles and methods for their preparation and use |
| JP6251667B2 (ja) | 2014-06-03 | 2017-12-20 | アサヒカルピスウェルネス株式会社 | 錠剤型即放性製剤及びその製造方法 |
| US9526734B2 (en) | 2014-06-09 | 2016-12-27 | Iceutica Pty Ltd. | Formulation of meloxicam |
| TR201905694T4 (tr) * | 2014-08-18 | 2019-05-21 | Alkermes Pharma Ireland Ltd | Aripiprazol ön ilaç bileşimleri. |
| SMT202100481T1 (it) | 2014-08-18 | 2021-09-14 | Alkermes Pharma Ireland Ltd | Composizioni per profarmaci di aripiprazolo |
| US10016415B2 (en) | 2014-08-18 | 2018-07-10 | Alkermes Pharma Ireland Limited | Aripiprazole prodrug compositions |
| RS59490B1 (sr) | 2014-11-21 | 2019-12-31 | Biohaven Therapeutics Ltd | Sublingvalna formulacija riluzola |
| KR20180082457A (ko) | 2015-10-16 | 2018-07-18 | 마리누스 파마슈티컬스 인코포레이티드 | 나노입자들을 포함하는 주사용 뉴로스테로이드 제제들 |
| WO2017105512A1 (en) * | 2015-12-18 | 2017-06-22 | Proinvet Innovations S.A. | Formulations and methods for controlling the reproductive cycle and ovulation |
| HRP20220237T1 (hr) | 2016-05-20 | 2022-04-29 | Biohaven Therapeutics Ltd. | Primjena riluzola, prolijekova riluzola ili analoga riluzola sa imunoterapijama za liječenje raka |
| KR20230050474A (ko) | 2016-08-11 | 2023-04-14 | 오비드 테라퓨틱스 인크. | 간질 장애의 치료를 위한 방법 및 조성물 |
| US10391105B2 (en) | 2016-09-09 | 2019-08-27 | Marinus Pharmaceuticals Inc. | Methods of treating certain depressive disorders and delirium tremens |
| IL267689B2 (en) | 2016-12-31 | 2025-05-01 | Bioxcel Therapeutics Inc | Use of sublingual dexmedetomidine for the treatment of agitation |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| PT3706739T (pt) | 2017-11-12 | 2024-12-04 | Biohaven Therapeutics Ltd | Utilização de profármacos de riluzol para tratar ataxias |
| IL279713B2 (en) | 2018-06-27 | 2025-01-01 | Bioxcel Therapeutics Inc | Dexmedetomidine-containing layer compositions and methods for their production |
| CN108904506A (zh) * | 2018-07-27 | 2018-11-30 | 河南大华生物技术有限公司 | 一种地克珠利纳米粉末及其制备方法 |
| US20240180204A1 (en) * | 2018-10-26 | 2024-06-06 | REPS JAPAN Co., Ltd. | Pods of supplements that dissolve in liquid solutions and manufacturing methods thereof |
| US11266662B2 (en) | 2018-12-07 | 2022-03-08 | Marinus Pharmaceuticals, Inc. | Ganaxolone for use in prophylaxis and treatment of postpartum depression |
| US20200405693A1 (en) * | 2019-06-25 | 2020-12-31 | Primus Pharmaceuticals, Inc. | Reduced dose metaxalone formulations |
| EP3999058A4 (en) | 2019-07-19 | 2023-05-03 | Bioxcel Therapeutics, Inc. | TREATMENT SCHEMES FOR NON-SEDATING DEXMEDETOMIDIN |
| EP4009982A4 (en) | 2019-08-05 | 2023-08-09 | Marinus Pharmaceuticals, Inc. | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS |
| AU2020395254B2 (en) | 2019-12-06 | 2026-04-02 | Marinus Pharmaceuticals, Inc. | Ganaxolone for use in treating tuberous sclerosis complex |
| US12285540B2 (en) * | 2020-07-21 | 2025-04-29 | Ethicon, Inc. | Hemostatic composite aggregate materials having surface enriched with hemostatis-promoting agents |
| WO2022155564A1 (en) | 2021-01-18 | 2022-07-21 | Biohaven Therapeutics Ltd. | Use of riluzole prodrugs to treat alzheimer's disease |
| CA3221395A1 (en) | 2021-06-10 | 2022-12-15 | Neurelis, Inc. | Methods and compositions for treating seizure disorders in pediatric patients |
| EP4434513A4 (en) * | 2021-11-16 | 2025-11-19 | Beijing Tide Pharmaceutical Co Ltd | NANOCRYSTALLINE PREPARATION OF ROCK2 INHIBITOR AND ITS PREPARATION PROCESS |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
Family Cites Families (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2403078A1 (fr) | 1977-09-19 | 1979-04-13 | Lafon Labor | Nouveau procede de preparation de formes pharmaceutiques, cosmetiques ou de diagnostic |
| FR2561916B1 (fr) | 1984-03-30 | 1987-12-11 | Lafon Labor | Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau |
| US4826689A (en) | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
| US4783484A (en) | 1984-10-05 | 1988-11-08 | University Of Rochester | Particulate composition and use thereof as antimicrobial agent |
| US4642903A (en) | 1985-03-26 | 1987-02-17 | R. P. Scherer Corporation | Freeze-dried foam dosage form |
| FR2634376B1 (fr) * | 1988-07-21 | 1992-04-17 | Farmalyoc | Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation |
| US5073374A (en) | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
| US5112616A (en) | 1988-11-30 | 1992-05-12 | Schering Corporation | Fast dissolving buccal tablet |
| FR2685635B1 (fr) * | 1991-12-27 | 1995-06-30 | Lvmh Rech | Particules solides complexes comprenant une substance solide biologiquement active, leur mode de preparation et compositions a usage topique les renfermant destinees au traitement de surfaces biologiques. |
| US5219574A (en) | 1989-09-15 | 1993-06-15 | Cima Labs. Inc. | Magnesium carbonate and oil tableting aid and flavoring additive |
| US5223264A (en) | 1989-10-02 | 1993-06-29 | Cima Labs, Inc. | Pediatric effervescent dosage form |
| US5178878A (en) | 1989-10-02 | 1993-01-12 | Cima Labs, Inc. | Effervescent dosage form with microparticles |
| US5188825A (en) | 1989-12-28 | 1993-02-23 | Iles Martin C | Freeze-dried dosage forms and methods for preparing the same |
| GB9005498D0 (en) | 1990-03-12 | 1990-05-09 | Beecham Group Plc | Composition |
| US5110605A (en) | 1990-08-21 | 1992-05-05 | Oramed, Inc. | Calcium polycarbophil-alginate controlled release composition and method |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| AU642066B2 (en) | 1991-01-25 | 1993-10-07 | Nanosystems L.L.C. | X-ray contrast compositions useful in medical imaging |
| US5399363A (en) | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
| US5552160A (en) | 1991-01-25 | 1996-09-03 | Nanosystems L.L.C. | Surface modified NSAID nanoparticles |
| GB2257707B (en) * | 1991-05-27 | 1995-11-01 | Nippon Zeon Co | Adhesive composition |
| AU2317592A (en) | 1991-07-05 | 1993-02-11 | University Of Rochester | Ultrasmall non-aggregated porous particles entrapping gas-bubbles |
| US5464632C1 (en) | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
| US5215758A (en) | 1991-09-11 | 1993-06-01 | Euroceltique, S.A. | Controlled release matrix suppository for pharmaceuticals |
| US5610294A (en) | 1991-10-11 | 1997-03-11 | The Du Pont Merck Pharmaceutical Company | Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors |
| DE4203932A1 (de) | 1992-02-11 | 1993-08-12 | Deutsche Aerospace | Sende-/empfangsmodul |
| NZ248813A (en) | 1992-11-25 | 1995-06-27 | Eastman Kodak Co | Polymeric grinding media used in grinding pharmaceutical substances |
| US5349957A (en) | 1992-12-02 | 1994-09-27 | Sterling Winthrop Inc. | Preparation and magnetic properties of very small magnetite-dextran particles |
| US5298262A (en) | 1992-12-04 | 1994-03-29 | Sterling Winthrop Inc. | Use of ionic cloud point modifiers to prevent particle aggregation during sterilization |
| US5346702A (en) | 1992-12-04 | 1994-09-13 | Sterling Winthrop Inc. | Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization |
| US5302401A (en) | 1992-12-09 | 1994-04-12 | Sterling Winthrop Inc. | Method to reduce particle size growth during lyophilization |
| US5340564A (en) | 1992-12-10 | 1994-08-23 | Sterling Winthrop Inc. | Formulations comprising olin 10-G to prevent particle aggregation and increase stability |
| US5336507A (en) | 1992-12-11 | 1994-08-09 | Sterling Winthrop Inc. | Use of charged phospholipids to reduce nanoparticle aggregation |
| US5429824A (en) | 1992-12-15 | 1995-07-04 | Eastman Kodak Company | Use of tyloxapole as a nanoparticle stabilizer and dispersant |
| US5352459A (en) | 1992-12-16 | 1994-10-04 | Sterling Winthrop Inc. | Use of purified surface modifiers to prevent particle aggregation during sterilization |
| US5401492A (en) | 1992-12-17 | 1995-03-28 | Sterling Winthrop, Inc. | Water insoluble non-magnetic manganese particles as magnetic resonance contract enhancement agents |
| US5326552A (en) | 1992-12-17 | 1994-07-05 | Sterling Winthrop Inc. | Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants |
| US5503846A (en) | 1993-03-17 | 1996-04-02 | Cima Labs, Inc. | Base coated acid particles and effervescent formulation incorporating same |
| US5264610A (en) | 1993-03-29 | 1993-11-23 | Sterling Winthrop Inc. | Iodinated aromatic propanedioates |
| US5811404A (en) | 1993-05-14 | 1998-09-22 | Cytel Corporation | Sialyl Lex analogues as inhibitors of cellular adhesion |
| US5631553A (en) * | 1993-05-31 | 1997-05-20 | Universite Du Quebec A Trois-Rivieres | High precision RF vector analysis system based on synchronous sampling |
| ATE208615T1 (de) | 1993-07-09 | 2001-11-15 | Scherer Corp R P | Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen |
| US5851553A (en) | 1993-09-10 | 1998-12-22 | Fuisz Technologies, Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
| US5622719A (en) | 1993-09-10 | 1997-04-22 | Fuisz Technologies Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
| US5895664A (en) | 1993-09-10 | 1999-04-20 | Fuisz Technologies Ltd. | Process for forming quickly dispersing comestible unit and product therefrom |
| US5595761A (en) | 1994-01-27 | 1997-01-21 | The Board Of Regents Of The University Of Oklahoma | Particulate support matrix for making a rapidly dissolving tablet |
| US5576014A (en) | 1994-01-31 | 1996-11-19 | Yamanouchi Pharmaceutical Co., Ltd | Intrabuccally dissolving compressed moldings and production process thereof |
| US5635210A (en) | 1994-02-03 | 1997-06-03 | The Board Of Regents Of The University Of Oklahoma | Method of making a rapidly dissolving tablet |
| US5718388A (en) | 1994-05-25 | 1998-02-17 | Eastman Kodak | Continuous method of grinding pharmaceutical substances |
| TW384224B (en) | 1994-05-25 | 2000-03-11 | Nano Sys Llc | Method of preparing submicron particles of a therapeutic or diagnostic agent |
| US5567439A (en) | 1994-06-14 | 1996-10-22 | Fuisz Technologies Ltd. | Delivery of controlled-release systems(s) |
| US5525328A (en) | 1994-06-24 | 1996-06-11 | Nanosystems L.L.C. | Nanoparticulate diagnostic diatrizoxy ester X-ray contrast agents for blood pool and lymphatic system imaging |
| US5587143A (en) | 1994-06-28 | 1996-12-24 | Nanosystems L.L.C. | Butylene oxide-ethylene oxide block copolymer surfactants as stabilizer coatings for nanoparticle compositions |
| US5567172A (en) * | 1994-09-26 | 1996-10-22 | Aer Energy Resources, Inc. | Universal strain relief device for connectors |
| GB9421836D0 (en) | 1994-10-28 | 1994-12-14 | Scherer Corp R P | Process for preparing solid pharmaceutical dosage forms of hydrophobic substances |
| DE4440337A1 (de) * | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
| US5628981A (en) | 1994-12-30 | 1997-05-13 | Nano Systems L.L.C. | Formulations of oral gastrointestinal diagnostic x-ray contrast agents and oral gastrointestinal therapeutic agents |
| US5466440A (en) | 1994-12-30 | 1995-11-14 | Eastman Kodak Company | Formulations of oral gastrointestinal diagnostic X-ray contrast agents in combination with pharmaceutically acceptable clays |
| US5585108A (en) | 1994-12-30 | 1996-12-17 | Nanosystems L.L.C. | Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays |
| US5662883A (en) | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
| US5665331A (en) | 1995-01-10 | 1997-09-09 | Nanosystems L.L.C. | Co-microprecipitation of nanoparticulate pharmaceutical agents with crystal growth modifiers |
| US5560932A (en) | 1995-01-10 | 1996-10-01 | Nano Systems L.L.C. | Microprecipitation of nanoparticulate pharmaceutical agents |
| US5569448A (en) | 1995-01-24 | 1996-10-29 | Nano Systems L.L.C. | Sulfated nonionic block copolymer surfactants as stabilizer coatings for nanoparticle compositions |
| US5639475A (en) | 1995-02-03 | 1997-06-17 | Eurand America, Incorporated | Effervescent microcapsules |
| US5560931A (en) | 1995-02-14 | 1996-10-01 | Nawosystems L.L.C. | Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids |
| US5571536A (en) | 1995-02-06 | 1996-11-05 | Nano Systems L.L.C. | Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids |
| US5534270A (en) | 1995-02-09 | 1996-07-09 | Nanosystems Llc | Method of preparing stable drug nanoparticles |
| US5593657A (en) | 1995-02-09 | 1997-01-14 | Nanosystems L.L.C. | Barium salt formulations stabilized by non-ionic and anionic stabilizers |
| US5622938A (en) | 1995-02-09 | 1997-04-22 | Nano Systems L.L.C. | Sugar base surfactant for nanocrystals |
| US5518738A (en) | 1995-02-09 | 1996-05-21 | Nanosystem L.L.C. | Nanoparticulate nsaid compositions |
| US5500204A (en) | 1995-02-10 | 1996-03-19 | Eastman Kodak Company | Nanoparticulate diagnostic dimers as x-ray contrast agents for blood pool and lymphatic system imaging |
| US5591456A (en) | 1995-02-10 | 1997-01-07 | Nanosystems L.L.C. | Milled naproxen with hydroxypropyl cellulose as a dispersion stabilizer |
| US5573783A (en) | 1995-02-13 | 1996-11-12 | Nano Systems L.L.C. | Redispersible nanoparticulate film matrices with protective overcoats |
| US5543133A (en) | 1995-02-14 | 1996-08-06 | Nanosystems L.L.C. | Process of preparing x-ray contrast compositions containing nanoparticles |
| US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US5580579A (en) | 1995-02-15 | 1996-12-03 | Nano Systems L.L.C. | Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers |
| US5718919A (en) | 1995-02-24 | 1998-02-17 | Nanosystems L.L.C. | Nanoparticles containing the R(-)enantiomer of ibuprofen |
| AU4990696A (en) | 1995-02-24 | 1996-09-11 | Nanosystems L.L.C. | Aerosols containing nanoparticle dispersions |
| US5747001A (en) | 1995-02-24 | 1998-05-05 | Nanosystems, L.L.C. | Aerosols containing beclomethazone nanoparticle dispersions |
| US5565188A (en) | 1995-02-24 | 1996-10-15 | Nanosystems L.L.C. | Polyalkylene block copolymers as surface modifiers for nanoparticles |
| US5573749A (en) | 1995-03-09 | 1996-11-12 | Nano Systems L.L.C. | Nanoparticulate diagnostic mixed carboxylic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging |
| US5472683A (en) | 1995-03-09 | 1995-12-05 | Eastman Kodak Company | Nanoparticulate diagnostic mixed carbamic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging |
| US5643552A (en) | 1995-03-09 | 1997-07-01 | Nanosystems L.L.C. | Nanoparticulate diagnostic mixed carbonic anhydrides as x-ray contrast agents for blood pool and lymphatic system imaging |
| US5521218A (en) | 1995-05-15 | 1996-05-28 | Nanosystems L.L.C. | Nanoparticulate iodipamide derivatives for use as x-ray contrast agents |
| US5573750A (en) | 1995-05-22 | 1996-11-12 | Nanosystems L.L.C. | Diagnostic imaging x-ray contrast agents |
| US5607697A (en) | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
| US5811388A (en) | 1995-06-07 | 1998-09-22 | Cibus Pharmaceutical, Inc. | Delivery of drugs to the lower GI tract |
| US5834025A (en) | 1995-09-29 | 1998-11-10 | Nanosystems L.L.C. | Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions |
| US5807578A (en) | 1995-11-22 | 1998-09-15 | Lab Pharmaceutical Research International Inc. | Fast-melt tablet and method of making same |
| US5807577A (en) | 1995-11-22 | 1998-09-15 | Lab Pharmaceutical Research International Inc. | Fast-melt tablet and method of making same |
| US6045829A (en) | 1997-02-13 | 2000-04-04 | Elan Pharma International Limited | Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers |
| WO1998035666A1 (en) | 1997-02-13 | 1998-08-20 | Nanosystems Llc | Formulations of nanoparticle naproxen tablets |
| US5811425A (en) | 1997-03-04 | 1998-09-22 | Abbott Laboratories | Heterocyclic compounds as COX-2 inhibitors |
| US6024981A (en) | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
| US5869098A (en) | 1997-08-20 | 1999-02-09 | Fuisz Technologies Ltd. | Fast-dissolving comestible units formed under high-speed/high-pressure conditions |
| WO1999018934A1 (en) * | 1997-10-09 | 1999-04-22 | Vanderbilt University | Micro-particulate and nano-particulate polymeric delivery system |
| WO1999065469A2 (en) * | 1998-06-19 | 1999-12-23 | Rtp Pharma Inc. | Processes to generate submicron particles of water-insoluble compounds |
| US6153225A (en) | 1998-08-13 | 2000-11-28 | Elan Pharma International Limited | Injectable formulations of nanoparticulate naproxen |
| CA2341352C (en) | 1998-09-01 | 2013-01-08 | Elan Corporation Plc | Oral vaccine compositions |
| US6165506A (en) | 1998-09-04 | 2000-12-26 | Elan Pharma International Ltd. | Solid dose form of nanoparticulate naproxen |
| AU6283299A (en) | 1998-10-01 | 2000-04-17 | Elan Pharma International Limited | Controlled release nanoparticulate compositions |
| US8293277B2 (en) | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
| US6428814B1 (en) | 1999-10-08 | 2002-08-06 | Elan Pharma International Ltd. | Bioadhesive nanoparticulate compositions having cationic surface stabilizers |
| US6375986B1 (en) * | 2000-09-21 | 2002-04-23 | Elan Pharma International Ltd. | Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate |
| US6270806B1 (en) | 1999-03-03 | 2001-08-07 | Elan Pharma International Limited | Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions |
| US6267989B1 (en) | 1999-03-08 | 2001-07-31 | Klan Pharma International Ltd. | Methods for preventing crystal growth and particle aggregation in nanoparticulate compositions |
| US6811813B1 (en) * | 1999-05-19 | 2004-11-02 | Sarnoff Corporation | Method of coating micrometer sized inorganic particles |
| US6528981B1 (en) * | 1999-07-23 | 2003-03-04 | Fujitsu Limited | Low-voltage current mirror circuit |
| EP1204869B1 (en) * | 1999-08-17 | 2008-10-22 | Luminex Corporation | Method for analyzing a number of samples from a variety of sources for a single analyte |
| WO2001041770A2 (en) * | 1999-12-08 | 2001-06-14 | Pharmacia Corporation | Nanoparticulate eplerenone compositions |
| CO5261556A1 (es) * | 1999-12-08 | 2003-03-31 | Pharmacia Corp | Composiciones inhibidoras de ciclooxigenasa-2 que tiene rapido acceso de efecto terapeutico |
| KR100717549B1 (ko) * | 1999-12-22 | 2007-05-11 | 파마시아 코포레이션 | 시클로옥시게나제-2 억제제의 이중-방출 조성물 |
| US6316029B1 (en) | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
| US20040033267A1 (en) * | 2002-03-20 | 2004-02-19 | Elan Pharma International Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
| US6589562B1 (en) | 2000-10-25 | 2003-07-08 | Salvona L.L.C. | Multicomponent biodegradable bioadhesive controlled release system for oral care products |
| EP1392441B1 (en) | 2001-06-05 | 2008-07-23 | Elan Pharma International Limited | System and method for milling materials |
| US7112340B2 (en) * | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
-
2002
- 2002-10-11 JP JP2003533905A patent/JP2005508939A/ja not_active Withdrawn
- 2002-10-11 AU AU2002334939A patent/AU2002334939A1/en not_active Abandoned
- 2002-10-11 WO PCT/US2002/032314 patent/WO2003030872A2/en not_active Ceased
- 2002-10-11 EP EP02800993A patent/EP1443912B1/en not_active Expired - Lifetime
- 2002-10-11 CA CA2463495A patent/CA2463495C/en not_active Expired - Lifetime
- 2002-10-11 AT AT02800993T patent/ATE371442T1/de active
- 2002-10-11 DE DE60222160T patent/DE60222160T2/de not_active Expired - Lifetime
- 2002-10-11 US US10/268,928 patent/US6908626B2/en not_active Expired - Lifetime
- 2002-10-11 PT PT02800993T patent/PT1443912E/pt unknown
- 2002-10-11 DK DK02800993T patent/DK1443912T3/da active
- 2002-10-11 ES ES02800993T patent/ES2292848T3/es not_active Expired - Lifetime
-
2007
- 2007-11-22 CY CY20071101497T patent/CY1107810T1/el unknown
-
2009
- 2009-10-21 JP JP2009242799A patent/JP2010047599A/ja not_active Withdrawn
-
2013
- 2013-06-17 JP JP2013126534A patent/JP2013209422A/ja not_active Withdrawn
-
2015
- 2015-03-05 JP JP2015043408A patent/JP2015108022A/ja not_active Withdrawn
-
2017
- 2017-02-02 JP JP2017017261A patent/JP2017075182A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2463495C (en) | 2011-05-24 |
| DE60222160T2 (de) | 2008-06-12 |
| WO2003030872A2 (en) | 2003-04-17 |
| US6908626B2 (en) | 2005-06-21 |
| PT1443912E (pt) | 2007-11-28 |
| CA2463495A1 (en) | 2003-04-17 |
| JP2015108022A (ja) | 2015-06-11 |
| DE60222160D1 (de) | 2007-10-11 |
| CY1107810T1 (el) | 2013-06-19 |
| EP1443912B1 (en) | 2007-08-29 |
| JP2010047599A (ja) | 2010-03-04 |
| JP2005508939A (ja) | 2005-04-07 |
| ATE371442T1 (de) | 2007-09-15 |
| US20030137067A1 (en) | 2003-07-24 |
| WO2003030872A3 (en) | 2003-07-31 |
| ES2292848T3 (es) | 2008-03-16 |
| EP1443912A2 (en) | 2004-08-11 |
| JP2013209422A (ja) | 2013-10-10 |
| AU2002334939A1 (en) | 2003-04-22 |
| JP2017075182A (ja) | 2017-04-20 |
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