BRPI0606280A2 - composições de bisfosfonato nanoparticulado - Google Patents
composições de bisfosfonato nanoparticuladoInfo
- Publication number
- BRPI0606280A2 BRPI0606280A2 BRPI0606280-6A BRPI0606280A BRPI0606280A2 BR PI0606280 A2 BRPI0606280 A2 BR PI0606280A2 BR PI0606280 A BRPI0606280 A BR PI0606280A BR PI0606280 A2 BRPI0606280 A2 BR PI0606280A2
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- nanoparticulate bisphosphonate
- bisphosphonate compositions
- nanoparticulate
- bisphosphonate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
COMPOSIçõES DE BISFOSFONATO NANOPARTICULADO. A presente invenção refere-se a composições de bisfosfonato nanoparticulado que tem um tamanho médio de partícula de menos do que 2000 nm, e que são descritas. As composições são úteis para tratar a reabsorção de osso em um mamífero.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66269305P | 2005-03-17 | 2005-03-17 | |
PCT/US2006/009791 WO2006102117A1 (en) | 2005-03-17 | 2006-03-17 | Nanoparticulate biphosphonate compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0606280A2 true BRPI0606280A2 (pt) | 2009-06-09 |
Family
ID=36636203
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0606280-6A BRPI0606280A2 (pt) | 2005-03-17 | 2006-03-17 | composições de bisfosfonato nanoparticulado |
Country Status (15)
Country | Link |
---|---|
US (2) | US8158153B2 (pt) |
EP (1) | EP1865928A1 (pt) |
JP (1) | JP2008533173A (pt) |
KR (1) | KR20070121759A (pt) |
CN (1) | CN101198316A (pt) |
AU (1) | AU2006227399A1 (pt) |
BR (1) | BRPI0606280A2 (pt) |
CA (1) | CA2601363A1 (pt) |
EA (1) | EA200701997A1 (pt) |
IL (1) | IL185953A0 (pt) |
MX (1) | MX2007011495A (pt) |
NO (1) | NO20075294L (pt) |
NZ (1) | NZ561666A (pt) |
WO (1) | WO2006102117A1 (pt) |
ZA (1) | ZA200708457B (pt) |
Families Citing this family (94)
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US20080287400A1 (en) * | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
US7645459B2 (en) * | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of bisphosphonates |
US7645460B2 (en) * | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of risedronate |
US20080286359A1 (en) * | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
ES2426445T3 (es) * | 2006-04-07 | 2013-10-23 | Merrion Research Iii Limited | Forma de dosificación oral sólida que contiene un potenciador |
JP2009538927A (ja) | 2006-05-30 | 2009-11-12 | エラン ファーマ インターナショナル,リミティド | ナノ粒子状のポサコナゾール製剤 |
CA2654566A1 (en) * | 2006-06-09 | 2007-12-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
WO2008005509A2 (en) * | 2006-07-06 | 2008-01-10 | Massachusetts Institute Of Technology | Methods and compositions for altering biological surfaces |
CN101500546A (zh) * | 2006-08-17 | 2009-08-05 | 诺瓦提斯公司 | 纳米粒组合物 |
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KR101012903B1 (ko) * | 2008-08-20 | 2011-02-08 | 한국콜마 주식회사 | 나노입자 형성을 이용하는 리세드로네이트 경질캡슐 |
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EP3494974B1 (en) * | 2011-07-08 | 2023-10-18 | The University of North Carolina at Chapel Hill | Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders |
KR101324425B1 (ko) * | 2011-07-22 | 2013-11-01 | 동아에스티 주식회사 | 증가된 비스포스포네이트의 생체이용률을 가지는 경구투여 약제 |
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US9211257B2 (en) | 2012-05-14 | 2015-12-15 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
US9956234B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
US9895383B2 (en) | 2012-05-14 | 2018-02-20 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
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US9956238B2 (en) | 2014-05-15 | 2018-05-01 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US9867840B2 (en) | 2014-05-27 | 2018-01-16 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9795622B2 (en) | 2012-05-14 | 2017-10-24 | Antecip Bioventures Ii Llc | Neridronic acid for treating pain associated with a joint |
US10080765B2 (en) | 2012-05-14 | 2018-09-25 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
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2006
- 2006-03-17 JP JP2008502110A patent/JP2008533173A/ja active Pending
- 2006-03-17 BR BRPI0606280-6A patent/BRPI0606280A2/pt not_active Application Discontinuation
- 2006-03-17 EP EP06748432A patent/EP1865928A1/en not_active Withdrawn
- 2006-03-17 KR KR1020077023753A patent/KR20070121759A/ko not_active Application Discontinuation
- 2006-03-17 AU AU2006227399A patent/AU2006227399A1/en not_active Abandoned
- 2006-03-17 WO PCT/US2006/009791 patent/WO2006102117A1/en active Application Filing
- 2006-03-17 MX MX2007011495A patent/MX2007011495A/es not_active Application Discontinuation
- 2006-03-17 CA CA002601363A patent/CA2601363A1/en not_active Abandoned
- 2006-03-17 CN CNA200680017268XA patent/CN101198316A/zh active Pending
- 2006-03-17 NZ NZ561666A patent/NZ561666A/en not_active IP Right Cessation
- 2006-03-17 EA EA200701997A patent/EA200701997A1/ru unknown
- 2006-03-17 US US11/377,650 patent/US8158153B2/en not_active Expired - Fee Related
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2007
- 2007-09-16 IL IL185953A patent/IL185953A0/en unknown
- 2007-10-03 ZA ZA200708457A patent/ZA200708457B/xx unknown
- 2007-10-16 NO NO20075294A patent/NO20075294L/no not_active Application Discontinuation
-
2011
- 2011-10-17 US US13/274,987 patent/US20120128780A1/en not_active Abandoned
Also Published As
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NO20075294L (no) | 2007-11-30 |
CN101198316A (zh) | 2008-06-11 |
US20120128780A1 (en) | 2012-05-24 |
CA2601363A1 (en) | 2006-09-28 |
WO2006102117A1 (en) | 2006-09-28 |
IL185953A0 (en) | 2008-01-06 |
AU2006227399A1 (en) | 2006-09-28 |
US8158153B2 (en) | 2012-04-17 |
US20060210639A1 (en) | 2006-09-21 |
NZ561666A (en) | 2010-05-28 |
KR20070121759A (ko) | 2007-12-27 |
JP2008533173A (ja) | 2008-08-21 |
ZA200708457B (en) | 2008-11-26 |
EA200701997A1 (ru) | 2008-02-28 |
MX2007011495A (es) | 2007-12-06 |
EP1865928A1 (en) | 2007-12-19 |
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