MX2010007076A - Nanodispersion. - Google Patents

Nanodispersion.

Info

Publication number
MX2010007076A
MX2010007076A MX2010007076A MX2010007076A MX2010007076A MX 2010007076 A MX2010007076 A MX 2010007076A MX 2010007076 A MX2010007076 A MX 2010007076A MX 2010007076 A MX2010007076 A MX 2010007076A MX 2010007076 A MX2010007076 A MX 2010007076A
Authority
MX
Mexico
Prior art keywords
nanodispersion
nanoparticles
salts
water
sterol
Prior art date
Application number
MX2010007076A
Other languages
English (en)
Inventor
Subhas Balaram Bhowmick
Ajay Jaysingh Khopade
N Arulsudar
Original Assignee
Sun Pharma Advanced Res Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40853553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2010007076(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sun Pharma Advanced Res Co Ltd filed Critical Sun Pharma Advanced Res Co Ltd
Publication of MX2010007076A publication Critical patent/MX2010007076A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

La presenta invención proporciona una nanodispersión que comprende nanoparticulas con un tamaño promedio de menos 300nm dispersas en un vehículo que comprende un solvente miscible en gua y agua, duchas nonoparticulas comprenden uno o más derivados de taxano, un polímero y un agente tensoactivo que comprende una mezcla de ácidos grasos o sus sales y esterol o sus derivados o sus sales.
MX2010007076A 2007-12-24 2008-12-23 Nanodispersion. MX2010007076A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2527MU2007 2007-12-24
PCT/IN2008/000857 WO2009087678A2 (en) 2007-12-24 2008-12-23 Nanodispersion

Publications (1)

Publication Number Publication Date
MX2010007076A true MX2010007076A (es) 2010-09-30

Family

ID=40853553

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010007076A MX2010007076A (es) 2007-12-24 2008-12-23 Nanodispersion.

Country Status (20)

Country Link
US (2) US8586062B2 (es)
EP (2) EP2853264A1 (es)
JP (2) JP5656643B2 (es)
KR (1) KR101505419B1 (es)
CN (1) CN101909614B (es)
AP (1) AP2895A (es)
AU (1) AU2008346121B2 (es)
BR (1) BRPI0821514B8 (es)
CA (1) CA2710525C (es)
CO (1) CO6290681A2 (es)
DK (1) DK2231144T3 (es)
EA (1) EA016434B1 (es)
ES (1) ES2509490T3 (es)
IL (1) IL206584A0 (es)
MX (1) MX2010007076A (es)
NZ (1) NZ586343A (es)
PL (1) PL2231144T3 (es)
UA (1) UA100543C2 (es)
WO (1) WO2009087678A2 (es)
ZA (1) ZA201004450B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010146606A1 (en) * 2009-06-19 2010-12-23 Sun Pharma Advanced Research Company Ltd., Nanodispersion of a drug and process for its preparation
CN102038635A (zh) 2009-10-23 2011-05-04 天津天士力集团有限公司 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法
KR20110056042A (ko) * 2009-11-20 2011-05-26 주식회사유한양행 종양세포 표적지향을 위한 나노 입자 및 이의 제조방법
CA2798180A1 (en) 2010-05-03 2011-11-10 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
ES2385995B2 (es) 2011-01-10 2013-05-21 Universidade De Santiago De Compostela Nanocápsulas con cubierta polimérica
CN102078300B (zh) * 2011-01-27 2012-01-11 海南美大制药有限公司 托拉塞米脂质体固体制剂
CN102366409B (zh) * 2011-09-14 2013-03-20 海南灵康制药有限公司 一种尼扎替丁脂质体固体制剂
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
WO2014153042A1 (en) * 2013-03-14 2014-09-25 Griffith Laboratories International, Inc. Natural fungicide composition
US20170099833A1 (en) * 2014-05-30 2017-04-13 Oms Investments, Inc. Nano-sized water-based dispersion compositions and methods of making thereof
KR101692314B1 (ko) * 2015-03-27 2017-01-03 주식회사 주빅 지용성 약물의 생분해성 고분자 내 용해 시스템: 스마트 폴리머 시스템
US20160346219A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
WO2016199169A1 (en) 2015-06-09 2016-12-15 Sun Pharma Advanced Research Company Ltd Picn-01
CN107551390A (zh) * 2017-08-21 2018-01-09 常熟佳禾生物科技有限公司 一种用于治疗乳腺小叶增生的中药文胸贴片及其制备方法
EP3768274B1 (en) * 2018-03-19 2023-11-15 Epicyt Pharma AB Composition comprising a combination of glycocholic acid and butyric acid or oleic acid for use in the treatment of osteoporosis
US11423574B2 (en) 2019-12-17 2022-08-23 Emma Ruccio Method and apparatus for detecting scoliosis
US11877717B2 (en) 2019-12-17 2024-01-23 Emma Ruccio Method and apparatus for detecting scoliosis

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6018A (en) * 1849-01-09 Improvement in bog-cutters
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
US6537579B1 (en) 1993-02-22 2003-03-25 American Bioscience, Inc. Compositions and methods for administration of pharmacologically active compounds
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
KR19990075621A (ko) 1998-03-23 1999-10-15 임성주 경사 평판형 배양조
US6017948A (en) 1998-10-30 2000-01-25 Supergen, Inc. Water-miscible pharmaceutical compositions
US6365191B1 (en) 1999-02-17 2002-04-02 Dabur Research Foundation Formulations of paclitaxel, its derivatives or its analogs entrapped into nanoparticles of polymeric micelles, process for preparing same and the use thereof
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
CA2383241C (en) * 1999-09-23 2009-01-20 Dabur Research Foundation Formulations of paclitaxel entrapped into nanoparticles of polymeric micelles
TWI230616B (en) 2000-09-25 2005-04-11 Ind Tech Res Inst Liposome for incorporating large amounts of hydrophobic substances
EP1387676A2 (en) * 2001-05-01 2004-02-11 Angiotech Pharmaceuticals, Inc. Compositions comprising an anti-microtubule agent and a polypeptide or a polysaccharide and the use thereof for the preparation of a medicament for the treatment of inflammatory conditions
DE10124952A1 (de) * 2001-05-21 2002-12-12 Bayer Ag Verfahren zur Herstellung von Nanodispersionen
US20040092428A1 (en) * 2001-11-27 2004-05-13 Hongming Chen Oral pharmaceuticals formulation comprising paclitaxel, derivatives and methods of administration thereof
US6780324B2 (en) * 2002-03-18 2004-08-24 Labopharm, Inc. Preparation of sterile stabilized nanodispersions
ITMI20022323A1 (it) * 2002-10-31 2004-05-01 Maria Rosa Gasco Composizioni farmaceutiche atte al trattamento di malattie oftalmiche.
US7670627B2 (en) * 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
US7345093B2 (en) * 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
US20050288521A1 (en) * 2004-06-29 2005-12-29 Phytogen Life Sciences Inc. Semi-synthetic conversion of paclitaxel to docetaxel
KR20080003322A (ko) * 2005-02-24 2008-01-07 엘란 파마 인터내셔널 리미티드 도세탁셀 및 이의 유사체의 나노입자 배합물
KR20080030024A (ko) 2005-06-17 2008-04-03 호스피라 오스트레일리아 피티와이 리미티드 도세탁셀의 약제학적 액상제제
WO2007069272A2 (en) * 2005-10-21 2007-06-21 Panacea Biotec Limited Pharmaceutical composition comprising at least one anticancer drug and at least one polymer
KR100917809B1 (ko) * 2006-05-22 2009-09-18 에스케이케미칼주식회사 우수한 저장안정성을 갖는 도세탁셀 함유 주사제 조성물
US20100068251A1 (en) * 2006-10-10 2010-03-18 Jina Pharmaceuticals, Inc. Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses Thereof

Also Published As

Publication number Publication date
EP2231144B1 (en) 2014-07-02
US20100297244A1 (en) 2010-11-25
CO6290681A2 (es) 2011-06-20
BRPI0821514A2 (pt) 2016-09-27
US20140030352A1 (en) 2014-01-30
US8586062B2 (en) 2013-11-19
KR20100112564A (ko) 2010-10-19
DK2231144T3 (da) 2014-10-13
AU2008346121A1 (en) 2009-07-16
EP2231144A4 (en) 2011-01-12
BRPI0821514B1 (pt) 2020-03-10
CA2710525A1 (en) 2009-07-16
AP2010005314A0 (en) 2010-08-31
WO2009087678A2 (en) 2009-07-16
WO2009087678A3 (en) 2009-09-11
ZA201004450B (en) 2011-03-30
CA2710525C (en) 2017-08-22
AP2895A (en) 2014-05-31
PL2231144T3 (pl) 2014-12-31
EP2231144A2 (en) 2010-09-29
ES2509490T3 (es) 2014-10-17
KR101505419B1 (ko) 2015-03-30
CN101909614B (zh) 2015-04-15
JP5656643B2 (ja) 2015-01-21
IL206584A0 (en) 2010-12-30
EA201070793A1 (ru) 2010-12-30
UA100543C2 (ru) 2013-01-10
NZ586343A (en) 2012-03-30
AU2008346121B2 (en) 2013-10-10
EP2853264A1 (en) 2015-04-01
CN101909614A (zh) 2010-12-08
BRPI0821514B8 (pt) 2021-05-25
JP5937180B2 (ja) 2016-06-22
EA016434B1 (ru) 2012-04-30
JP2011507946A (ja) 2011-03-10
JP2015110565A (ja) 2015-06-18

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