DK1437358T3 - Hidtil ukendt glycolipid og medikament til autoimmune sygdomme indeholdende dette som det aktive stof - Google Patents

Hidtil ukendt glycolipid og medikament til autoimmune sygdomme indeholdende dette som det aktive stof

Info

Publication number
DK1437358T3
DK1437358T3 DK02760637T DK02760637T DK1437358T3 DK 1437358 T3 DK1437358 T3 DK 1437358T3 DK 02760637 T DK02760637 T DK 02760637T DK 02760637 T DK02760637 T DK 02760637T DK 1437358 T3 DK1437358 T3 DK 1437358T3
Authority
DK
Denmark
Prior art keywords
drug
active substance
autoimmune diseases
gen
hitherto unknown
Prior art date
Application number
DK02760637T
Other languages
Danish (da)
English (en)
Inventor
Takashi Yamamura
Sachiko Miyake
Original Assignee
Daiichi Asubio Pharma Co Ltd
Japan Government
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Asubio Pharma Co Ltd, Japan Government filed Critical Daiichi Asubio Pharma Co Ltd
Application granted granted Critical
Publication of DK1437358T3 publication Critical patent/DK1437358T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK02760637T 2001-08-16 2002-08-14 Hidtil ukendt glycolipid og medikament til autoimmune sygdomme indeholdende dette som det aktive stof DK1437358T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001247055 2001-08-16
PCT/JP2002/008280 WO2003016326A1 (fr) 2001-08-16 2002-08-14 Glycolipide et agent therapeutique pour maladies auto-immunes le contenant en tant qu'ingredient actif

Publications (1)

Publication Number Publication Date
DK1437358T3 true DK1437358T3 (da) 2007-02-05

Family

ID=19076468

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02760637T DK1437358T3 (da) 2001-08-16 2002-08-14 Hidtil ukendt glycolipid og medikament til autoimmune sygdomme indeholdende dette som det aktive stof

Country Status (15)

Country Link
US (1) US8367623B2 (ja)
EP (1) EP1437358B1 (ja)
JP (1) JP4064346B2 (ja)
KR (1) KR100880063B1 (ja)
CN (1) CN100439383C (ja)
AT (1) ATE342910T1 (ja)
AU (1) AU2002327097B2 (ja)
BR (1) BR0211968A (ja)
CA (1) CA2459482C (ja)
DE (1) DE60215530T2 (ja)
DK (1) DK1437358T3 (ja)
ES (1) ES2274080T3 (ja)
HU (1) HU229345B1 (ja)
NO (1) NO326398B1 (ja)
WO (1) WO2003016326A1 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9809654B2 (en) 2002-09-27 2017-11-07 Vaccinex, Inc. Targeted CD1d molecules
ES2450043T3 (es) * 2003-02-14 2014-03-21 Japan As Represented By President Of National Center Of Neurology And Psychiatry Ministry Of Healt Derivados del glicolípido, proceso para su producción, intermedios para la síntesis del mismo, y proceso para la producción de los intermedios
JP5226311B2 (ja) * 2004-08-27 2013-07-03 アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ 免疫及び自己免疫の調節因子としてのセラミド誘導体
US8513008B2 (en) 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
TWI382843B (zh) 2004-10-07 2013-01-21 Argos Therapeutics Inc 成熟樹突細胞組合物及培養彼等之方法
US7923013B2 (en) 2004-12-28 2011-04-12 The Rockefeller University Glycolipids and analogues thereof as antigens for NKT cells
CA2591232C (en) * 2004-12-28 2014-10-21 The Rockefeller University Glycolipids and analogues thereof as antigens for nk t cells
EP1872794B1 (en) * 2005-04-01 2012-12-12 JAPAN as represented by DIRECTOR GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES Nasal vaccine
EP1905766A1 (en) * 2005-07-01 2008-04-02 Japan as represented by President of National Center of Neurology and Psychiatry Glycolipid derivative and therapeutic agent comprising the same as active ingredient
CN101316599A (zh) * 2005-10-28 2008-12-03 国立精神神经中心主席代表的日本国 抑制nkt细胞的机能的糖脂衍生物作为有效成分的治疗剂
WO2007099999A1 (ja) * 2006-02-28 2007-09-07 Riken 新規糖脂質及びその用途
US7794722B2 (en) 2006-06-30 2010-09-14 The Scripps Research Institute Adjuvants and methods of use
KR100868959B1 (ko) * 2006-12-30 2008-11-17 재단법인서울대학교산학협력재단 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물
JP5357782B2 (ja) 2007-02-21 2013-12-04 バクシネックス インコーポレーティッド 抗原負荷ＣＤ１ｄ分子によるＮＫＴ細胞活性の調節
ES2574825T3 (es) * 2007-10-12 2016-06-22 Luigi Panza Análogos de glicolípidos útiles como inmunoadyuvantes
JP2012514476A (ja) * 2009-01-08 2012-06-28 アルバート アインシュタイン カレッジ オブ メディシン オブ イェシバ ユニバーシティ，ア ディビジョン オブ イェシバ ユニバーシティ 細胞壁結合セラミド様糖脂質による細菌ワクチンおよびその使用
US9371352B2 (en) 2013-02-08 2016-06-21 Vaccinex, Inc. Modified glycolipids and methods of making and using the same
JP6202339B2 (ja) * 2013-12-19 2017-09-27 国立研究開発法人国立精神・神経医療研究センター ＧＭ−ＣＳＦ産生Ｔ細胞制御剤、及びＴｈ１／Ｔｈ２免疫バランス調節剤
WO2015129791A1 (ja) 2014-02-26 2015-09-03 国立大学法人北海道大学 樹状細胞を含有する医薬およびその製造方法
JPWO2021010344A1 (ja) 2019-07-12 2021-01-21

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5827828A (ja) * 1981-08-11 1983-02-18 Mitsubishi Electric Corp 燃料噴射装置
DK84691D0 (da) 1991-05-07 1991-05-07 Karsten Buschard Visse glycolipider og specifikke catchere for disse til anvendelse ved profylaxe eller terapi af diabetes, og/eller dermed forbundne komplikationer samt anvendelse af saadanne glycolipider til detektion af oe-celle-antistoffer (ica) i et individ og anvendelse af saadanne catchere til detektion af langerhans-oe-celler i pancreas-praeparater
JPH0559081A (ja) * 1991-08-29 1993-03-09 Kirin Brewery Co Ltd 新規スフインゴ糖脂質、その製造法および使用
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
GB9207182D0 (en) * 1992-04-01 1992-05-13 Enzymatix Ltd Glycolipids and their preparation
TW261533B (ja) 1992-07-16 1995-11-01 Kirin Brewery
CA2142153A1 (en) * 1994-03-04 1995-09-05 Jacques Banville Sulfated .beta.-glycolipid derivatives as cell adhesion inhibitors
US5861520A (en) * 1994-05-31 1999-01-19 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Glycolipid analogs
DE19602108A1 (de) * 1996-01-22 1997-07-24 Beiersdorf Ag Gegen Bakterien, Parasiten, Protozoen, Mycota und Viren wirksame Substanzen
JP4451933B2 (ja) * 1996-12-27 2010-04-14 住友化学株式会社 遺伝子操作による植物へのｐｐｏ阻害性除草剤耐性付与法
DE69828603T2 (de) 1997-04-10 2005-12-29 Kirin Beer K.K. Verwendung von a-Glycosylceramiden zur Herstellung eines therapeutischen Mittels zur Behandlung von Autoimmunkrankheiten
US6589940B1 (en) * 1997-06-06 2003-07-08 Dynavax Technologies Corporation Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
US7273711B1 (en) * 1998-12-02 2007-09-25 The Regents Of The University Of California Diagnosis of human glycosylation disorders
JP2002284692A (ja) * 2001-03-26 2002-10-03 Kirin Brewery Co Ltd α−グリコシルセラミドによる移植片対宿主病（ＧＶＨＤ）の抑制

Also Published As

Publication number Publication date
US20060148723A1 (en) 2006-07-06
HUP0500127A2 (en) 2006-09-28
CA2459482C (en) 2010-09-28
CN1568328A (zh) 2005-01-19
EP1437358B1 (en) 2006-10-18
ES2274080T3 (es) 2007-05-16
HU229345B1 (en) 2013-11-28
NO20040653L (no) 2004-05-07
KR100880063B1 (ko) 2009-01-22
US8367623B2 (en) 2013-02-05
EP1437358A1 (en) 2004-07-14
JPWO2003016326A1 (ja) 2004-12-02
DE60215530T2 (de) 2007-05-31
JP4064346B2 (ja) 2008-03-19
CN100439383C (zh) 2008-12-03
KR20040039287A (ko) 2004-05-10
EP1437358A4 (en) 2004-11-24
BR0211968A (pt) 2004-09-28
WO2003016326A1 (fr) 2003-02-27
HUP0500127A3 (en) 2009-12-28
NO326398B1 (no) 2008-11-24
AU2002327097B2 (en) 2007-05-24
CA2459482A1 (en) 2003-02-27
DE60215530D1 (de) 2006-11-30
ATE342910T1 (de) 2006-11-15

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