DK142987D0 - Hidtil ukendte vitamin d-analoger - Google Patents

Hidtil ukendte vitamin d-analoger

Info

Publication number
DK142987D0
DK142987D0 DK142987A DK142987A DK142987D0 DK 142987 D0 DK142987 D0 DK 142987D0 DK 142987 A DK142987 A DK 142987A DK 142987 A DK142987 A DK 142987A DK 142987 D0 DK142987 D0 DK 142987D0
Authority
DK
Denmark
Prior art keywords
analogs
vitamin
unknown
unknown vitamin
Prior art date
Application number
DK142987A
Other languages
English (en)
Other versions
DK142987A (da
DK166617B1 (da
Inventor
Martin John Calverley
Ernst Torndal Binderup
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26289597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK142987(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858519502A external-priority patent/GB8519502D0/en
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of DK142987A publication Critical patent/DK142987A/da
Publication of DK142987D0 publication Critical patent/DK142987D0/da
Application granted granted Critical
Publication of DK166617B1 publication Critical patent/DK166617B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK142987A 1985-08-02 1987-03-20 24-hydroxylerede d-vitamin-derivater og farmaceutiske praeparater indeholdende disse DK166617B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8519502 1985-08-02
GB858519502A GB8519502D0 (en) 1985-08-02 1985-08-02 Chemical compounds
PCT/DK1986/000081 WO1987000834A1 (en) 1985-08-02 1986-07-14 Novel vitamin d analogues
DK8600081 1986-07-14
PH34061A PH25496A (en) 1985-08-02 1986-08-11 New vitamin d analogues
PH3406186 1986-08-11

Publications (3)

Publication Number Publication Date
DK142987A DK142987A (da) 1987-03-20
DK142987D0 true DK142987D0 (da) 1987-03-20
DK166617B1 DK166617B1 (da) 1993-06-21

Family

ID=26289597

Family Applications (1)

Application Number Title Priority Date Filing Date
DK142987A DK166617B1 (da) 1985-08-02 1987-03-20 24-hydroxylerede d-vitamin-derivater og farmaceutiske praeparater indeholdende disse

Country Status (16)

Country Link
US (1) US4866048A (da)
EP (1) EP0227826B1 (da)
JP (1) JPH07100685B2 (da)
KR (1) KR940010767B1 (da)
AU (1) AU603340B2 (da)
CA (1) CA1307288C (da)
DE (1) DE3666587D1 (da)
DK (1) DK166617B1 (da)
ES (1) ES2000823A6 (da)
GR (1) GR862029B (da)
HK (1) HK63492A (da)
IE (1) IE58545B1 (da)
PH (1) PH25496A (da)
PT (1) PT83119B (da)
SG (1) SG64192G (da)
WO (1) WO1987000834A1 (da)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728643A (en) * 1984-11-02 1988-03-01 The General Hospital Corporation Method of treating psoriasis
JPS6218A (ja) * 1985-03-14 1987-01-06 Chugai Pharmaceut Co Ltd 皮膚疾患治療用組成物
FR2631025B1 (fr) * 1988-05-04 1991-04-12 Ire Medgenix Sa Nouveaux derives de la vitamine d3 et application aux dosages des metabolites de la vitamine d3
GB8816505D0 (en) * 1988-07-12 1988-08-17 Leo Pharm Prod Ltd Novel treatment
US4851401A (en) * 1988-07-14 1989-07-25 Wisconsin Alumni Research Foundation Novel cyclopentano-vitamin D analogs
GB8904154D0 (en) 1989-02-23 1989-04-05 Leo Pharm Prod Ltd Chemical compounds
IL97158A (en) * 1990-02-06 1994-12-29 Schering Ag Homologous histories of vitamin D in the side chain, processes for their preparation and pharmaceutical preparations containing them
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
GB9015774D0 (en) * 1990-07-18 1990-09-05 Leo Pharm Prod Ltd Novel treatment
GB9017890D0 (en) 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
US6025346A (en) * 1990-09-21 2000-02-15 Bone Care International, Inc. 1α-hydroxy vitamin D4 and novel intermediates and analogues
WO1992005130A1 (en) * 1990-09-21 1992-04-02 Lunar Corporation NOVEL 1α-HYDROXY VITAMIN D4 AND NOVEL INTERMEDIATES AND ANALOGUES
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
US5801164A (en) * 1990-09-21 1998-09-01 Bone Care International, Inc. Methods of treating osteoporosis prophylactically or therapeutically
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5786348A (en) * 1991-01-08 1998-07-28 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US6166000A (en) * 1991-01-08 2000-12-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-Dihydroxy vitamin . D.sub2
DE69233074T2 (de) * 1991-01-08 2004-03-18 Bone Care International Inc., Madison Verfahren zur Herstellung von 1-alpha-24-dihydroxy-Vitamin D2
US5182396A (en) * 1991-03-29 1993-01-26 Nisshin Flour Milling Co., Ltd. 1-hydroxyvitamin d derivatives
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
ATE143007T1 (de) * 1991-07-05 1996-10-15 Duphar Int Res Vitamin-d derivat, verfahren zu dessen herstellung sowie zwischenprodukte dafür
US5225569A (en) * 1991-08-09 1993-07-06 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds
US5182393A (en) * 1991-08-09 1993-01-26 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
US5288408A (en) * 1992-10-26 1994-02-22 Chemical Industry Consultants, Inc. Method of gelatin recovery and purification from encapsulation processes
US5247104A (en) * 1992-11-04 1993-09-21 Wisconsin Alumni Research Foundation Preparation of 1α, 24-dihydroxyvitamin D analogs
US5763426A (en) * 1993-01-15 1998-06-09 Leo Pharmaceutical Products Ltd. Crystalline form of a vitamin D analogue
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
DE4328217C2 (de) * 1993-08-21 1996-01-11 Lohmann Therapie Syst Lts Therapeutisches System zur Behandlung der Psoriasis
US5763429A (en) * 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US5565589A (en) * 1993-11-03 1996-10-15 Wisconsin Alumni Research Foundation 17-formyl-5,6-trans-vitamin D compounds
US5373004A (en) * 1993-11-24 1994-12-13 Wisconsin Alumni Research Foundation 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
AU700668B2 (en) * 1994-07-18 1999-01-14 Bone Care International, Inc. Synthesis of 1alpha-hydroxy vitamin D
DK128494A (da) * 1994-11-08 1996-05-09 Edel K Seidenschnur Behandling af keratinøse og psoriatiske sygdomstilstande med neglelak indeholdende vitamin D metabolit, eller derivat, og/eller vitamin A derivat
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
CH690075A5 (de) * 1995-07-11 2000-04-14 Cerbios Pharma Sa Verfahren zur Herstellung von 9,10-Secocholesta-5, 7, 10 (19)-trienen durch Reduktion der Epoxide.
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
US6929797B2 (en) * 1997-02-13 2005-08-16 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
DE19744127B4 (de) * 1997-10-01 2006-10-05 Schering Ag Neue Vitamin D-Derivate mit Cyclopropylringen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung sowie ihre Verwendung zur Herstellung von Arzneimitteln
CA2312060A1 (en) 1997-12-09 1999-06-17 Chugai Seiyaku Kabushiki Kaisha Lotions containing vitamin d3 derivatives
US6521608B1 (en) 1998-03-27 2003-02-18 Oregon Health & Science University Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders
US6552009B2 (en) 1998-07-16 2003-04-22 Gentrix Llc Compositions and methods of treating abnormal cell proliferation
US20010002396A1 (en) * 1998-07-16 2001-05-31 Charles Achkar Compositions and methods of treating skin conditions
US8263580B2 (en) * 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
US6410746B1 (en) * 1999-04-27 2002-06-25 Research Foundation Of State University Of New York, The Metal cataltsts and methods for making and using same
US6617681B1 (en) * 1999-06-28 2003-09-09 Intel Corporation Interposer and method of making same
US6524623B1 (en) * 1999-11-12 2003-02-25 Milton Hodosh Therapeutic compositions and methods of use thereof
EP1301479A2 (en) * 2000-07-18 2003-04-16 Bone Care International, Inc. STABILIZED 1$g(a)-HYDROXY VITAMIN D
WO2003018184A2 (en) 2001-08-27 2003-03-06 The Research Foundation Of State University Of New York Solid support dirhodium catalyst compositions and methods for making and using same
US7030051B2 (en) 2001-08-27 2006-04-18 The Research Foundation Of State University Of New York Dirhodium catalyst compositions and methods for using same
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
AU2002363959B2 (en) * 2001-12-03 2007-12-13 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
IL162920A0 (en) * 2002-01-10 2005-11-20 Va Pharmaceutical Ind Ltd Selective enzymatic esterification and solvolysis of epimeric vitamin d analog and separation of theepimers
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
WO2003087048A2 (en) * 2002-04-11 2003-10-23 Instytut Farmaceutyczny Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds
CA2489593C (en) * 2002-06-13 2009-09-29 Teva Pharmaceutical Industries Ltd Epimerization of analogs of vitamin d
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
AU2003291810A1 (en) * 2002-11-18 2004-06-15 Teva Pharmaceutical Industries Ltd. A crystallization method for purification of calcipotriene
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
KR101160698B1 (ko) 2003-06-27 2012-06-28 아사히 가세이 가부시키가이샤 세포 분화 억제제, 이것을 이용하는 세포 배양 방법, 배양 배지 및 배양된 세포주
US7122542B2 (en) 2003-07-30 2006-10-17 Rigel Pharmaceuticals, Inc. Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
US7205006B2 (en) * 2003-09-25 2007-04-17 Prime Pharmaceutical Corporation Mahonia aquifolium extract, extraction process and pharmaceutical composition containing the same
JP4667450B2 (ja) * 2004-03-18 2011-04-13 レオ ファーマ アクティーゼルスカブ ビタミンｄ類似体の立体選択的合成
US8362287B2 (en) * 2004-03-18 2013-01-29 Leo Pharma A/S Stereoselective synthesis of vitamin D analogues
ES2361389T3 (es) * 2004-04-02 2011-06-16 Leo Pharma A/S Nuevo método para la preparación de intermedios útiles para la síntesis de análogos de vitamina d.
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
TWI318203B (en) * 2004-09-01 2009-12-11 Leo Pharma As Epimerization of allylic alcohols
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
JP2006204292A (ja) * 2004-12-27 2006-08-10 Asahi Kasei Corp ヒト胚性幹細胞分化抑制剤
US8034788B2 (en) * 2005-05-10 2011-10-11 Dermipsor Ltd. Composition and methods for skin care
AU2006245283B2 (en) 2005-05-10 2012-11-01 Dermipsor Ltd. Compositions and methods for treating hyperproliferative epidermal diseases
PL2526930T3 (pl) * 2005-06-01 2014-05-30 Glaxosmithkline Ip Dev Ltd Formulacja witaminowa
US7700798B1 (en) 2005-06-08 2010-04-20 The Research Foundation Of State University Of New York Erogorgiaene congeners and methods and intermediates useful in the preparation of same
US7816536B2 (en) * 2005-06-10 2010-10-19 The Research Foundation Of State University Of New York 4-substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles and methods for making same
CA2607901C (en) 2005-06-13 2016-08-16 Rigel Pharmaceuticals, Inc. Methods and compositions for treating degenerative bone disorders using a syk inhibitory 2,4-pyrimidinediamine
CA2612408A1 (en) * 2005-06-15 2006-12-28 Apollo Pharmaceutical, Inc. Pharmaceutical composition comprising a mahonia aquifolium extract for the treatment of psoriasis
ES2279500T3 (es) * 2005-06-17 2007-08-16 Magneti Marelli Powertrain S.P.A. Inyector de carburante.
TW200714580A (en) * 2005-10-14 2007-04-16 Formosa Lab Inc Process for preparing vitamin D analogs
US7385064B1 (en) 2005-11-30 2008-06-10 The Research Foundation Of State University Of New York Catalysts for use in enantioselective synthesis
BRPI0621471A2 (pt) 2006-03-17 2012-09-11 Leo Pharma As métodos de isomerização de uma solução de um derivado de vitamina d, para produzir e preparar calcipotriol ou monoidrato de calcipotriol, e para a fabricação de uma formulação farmacêutica ou medicamento, e, uso de um reator foto-reator de fluxo direto ou foto-reator de fluxo contìnuo
US20080051375A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
EP2063963A2 (en) 2006-08-25 2009-06-03 Cougar Biotechnology, Inc. Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
KR20090039833A (ko) * 2006-08-29 2009-04-22 테바 파마슈티컬 인더스트리즈 리미티드 비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물
ES2272198B1 (es) * 2006-12-28 2008-06-01 Laboratorios Viñas S.A. Procedimiento para la obtencion de hidrato de calcipotriol.
US20090124587A1 (en) * 2007-07-12 2009-05-14 Auerbach Alan H METHODS FOR TREATING CANCER USING 17alpha-HYDROXYLASE/C17,20-LYASE INHIBITORS
US8716334B2 (en) * 2008-06-17 2014-05-06 Ben Gurion University Of The Negev Research And Development Authority Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
SG173119A1 (en) 2009-01-27 2011-08-29 Berg Biosystems Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
US20120184514A1 (en) * 2009-07-01 2012-07-19 Vitamin Derivatives Inc. Vitamin d compounds and methods for preparing same
BR112012003372A2 (pt) 2009-08-14 2019-09-24 Berg Biosystems Llc vitamina d3 e análogos da mesma para o tratamento de alopecia.
EP2515913A2 (en) * 2009-12-23 2012-10-31 Glycomyr Inc. Use of vitamin d glycosides and sulfates for treatment of disease
WO2012158794A1 (en) 2011-05-17 2012-11-22 Wisconsin Alumni Research Foundation N-cyclopropyl-(20r)-2-methylene-19,26,27-trinor-25-aza-vitamin d analogs and their uses
CN103508999B (zh) * 2013-10-12 2015-05-13 浙江海正药业股份有限公司 马沙骨化醇的合成中间体及其制备方法和用途
CN103694156B (zh) * 2014-01-07 2015-09-02 成都医路康医学技术服务有限公司 一种银屑病治疗药物钙泊三醇的制备方法
CN105348164B (zh) * 2015-10-29 2017-03-29 无锡福祈制药有限公司 一种1α‑羟基维生素D2的制备方法
WO2017209934A1 (en) 2016-05-13 2017-12-07 Case Western Reserve University Autophagy activators for treating or preventing skin injury
CN107501150A (zh) * 2016-06-14 2017-12-22 江苏吉贝尔药业股份有限公司 两种他卡西醇中间体的制备方法
KR20240115925A (ko) 2016-07-29 2024-07-26 얀센 파마슈티카 엔브이 전립선암의 치료 방법
CN110156836A (zh) * 2019-06-10 2019-08-23 成家钢 一种环丙基羰基亚甲基三苯基磷的制备方法
CN111662221B (zh) * 2020-06-29 2022-04-19 重庆华邦胜凯制药有限公司 一种卡泊三醇杂质的制备方法
CN115177586A (zh) * 2022-08-31 2022-10-14 江苏知原药业股份有限公司 一种卡泊三醇组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
JPS5945673B2 (ja) * 1978-01-16 1984-11-07 ウイスコンシン・アラムナイ・リサ−チ・フオンデ−シヨン シクロビタミンｄ誘導体
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4335120A (en) * 1979-03-21 1982-06-15 Hoffmann-La Roche Inc. Administration of biologically active vitamin D3 and vitamin D2 materials
JPS57109765A (en) * 1980-12-27 1982-07-08 Wisconsin Alumni Res Found Preparation of 1-hydroxylated vitamin d compound from 5,6-trans-vitamin d compound
JPS57149224A (en) * 1981-03-13 1982-09-14 Chugai Pharmaceut Co Ltd Tumor-suppressing agent
US4442093A (en) * 1981-05-15 1984-04-10 Kureha Kagaku Kogyo Kabushiki Kaisha Method for administering 24,25-dihydroxycholecalciferol to persons suffering from hypercalcemia
JPS58208224A (ja) * 1982-05-28 1983-12-03 Kureha Chem Ind Co Ltd 抗腫瘍剤
JPS59104358A (ja) * 1982-12-03 1984-06-16 Teijin Ltd １α，２４−ジヒドロキシコレカルシフエロ−ルの一水塩及びその製造法
US4610978A (en) * 1983-03-22 1986-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same
JPS59186956A (ja) * 1983-04-07 1984-10-23 Teijin Ltd ２４−ヒドロキシ−２５−デヒドロビタミンｄ↓３類、その製造法及びそれを有効成分とするカルシウム調節剤
US4728643A (en) * 1984-11-02 1988-03-01 The General Hospital Corporation Method of treating psoriasis
US4661294A (en) * 1985-03-18 1987-04-28 The General Hospital Corporation Biologically active 1-thio derivatives of vitamin D

Also Published As

Publication number Publication date
IE861894L (en) 1987-02-02
PT83119B (pt) 1989-03-30
EP0227826A1 (en) 1987-07-08
CA1307288C (en) 1992-09-08
AU6196186A (en) 1987-03-05
DK142987A (da) 1987-03-20
AU603340B2 (en) 1990-11-15
KR940010767B1 (ko) 1994-11-11
US4866048A (en) 1989-09-12
DE3666587D1 (en) 1989-11-30
HK63492A (en) 1992-08-28
SG64192G (en) 1992-09-04
DK166617B1 (da) 1993-06-21
PT83119A (en) 1986-09-01
GR862029B (en) 1986-12-24
WO1987000834A1 (en) 1987-02-12
IE58545B1 (en) 1993-10-06
JPS63500661A (ja) 1988-03-10
JPH07100685B2 (ja) 1995-11-01
KR870700600A (ko) 1987-12-30
ES2000823A6 (es) 1988-03-16
PH25496A (en) 1991-07-24
EP0227826B1 (en) 1989-10-25

Similar Documents

Publication Publication Date Title
DK142987D0 (da) Hidtil ukendte vitamin d-analoger
DK191186D0 (da) Hidtil ukendte forbindelser
LU90099I2 (fr) Fluodioxonil (celest)
DK375686A (da) Viskaest cremeformigt skuremiddel
BR8605872A (pt) Combinada(ceifadeira-trilhadeira)
AT383496B (de) Ski
DK625086D0 (da) Hidtil ukendte forbindelser
DK90686D0 (da) Hidtil ukendte forbindelser
DK380886D0 (da) Hidtil ukendte forbindelser
DK390986D0 (da) Guaninderivater
DK311786D0 (da) Vitaminpraeparat
DK346786D0 (da) Hidtil ukendte forbindelser
DK340886D0 (da) Hidtil ukendte forbindelser
DK575286D0 (da) Hidtil ukendte forbindelser
DK625286D0 (da) Hidtil ukendte forbindelser
DK79986D0 (da) Hidtil ukendte forbindelser
IT1188262B (it) Sci
AT387149B (de) Ski
IT1204314B (it) Analoghi di tioprostaglandina 7-ossabicicloeptano sostituiti
DK284486D0 (da) Hidtil ukendte forbindelser
IT1204769B (it) Analoghi di ossaprostaglandina 7-ossabicicloeptano sostituiti
DK353286D0 (da) Hidtil ukendte forbindelser
FR2588489B1 (fr) Centrifugeuse
DK295486D0 (da) Hidtil ukendte forbindelser
ATA224785A (de) Stiefel

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired
PUP Patent expired