DK1425277T3 - Urinstof-forbindelser aktive som vanilloid-receptor-antagonister til behandling af smerte - Google Patents
Urinstof-forbindelser aktive som vanilloid-receptor-antagonister til behandling af smerteInfo
- Publication number
- DK1425277T3 DK1425277T3 DK02765023T DK02765023T DK1425277T3 DK 1425277 T3 DK1425277 T3 DK 1425277T3 DK 02765023 T DK02765023 T DK 02765023T DK 02765023 T DK02765023 T DK 02765023T DK 1425277 T3 DK1425277 T3 DK 1425277T3
- Authority
- DK
- Denmark
- Prior art keywords
- receptor antagonists
- urea compounds
- treat pain
- vanilloid receptor
- compounds active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0122156A GB0122156D0 (en) | 2001-09-13 | 2001-09-13 | Novel compounds |
GB0130547A GB0130547D0 (en) | 2001-12-20 | 2001-12-20 | Novel compounds |
GB0130503A GB0130503D0 (en) | 2001-12-20 | 2001-12-20 | Novel compounds |
GB0130505A GB0130505D0 (en) | 2001-12-20 | 2001-12-20 | Novel compounds |
PCT/GB2002/004206 WO2003022809A2 (en) | 2001-09-13 | 2002-09-13 | Urea-compounds active as vanilloid receptor antagonists for the treatment of pain |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1425277T3 true DK1425277T3 (da) | 2009-03-16 |
Family
ID=27447989
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02765023T DK1425277T3 (da) | 2001-09-13 | 2002-09-13 | Urinstof-forbindelser aktive som vanilloid-receptor-antagonister til behandling af smerte |
Country Status (32)
Country | Link |
---|---|
US (1) | US8063078B2 (sl) |
EP (3) | EP2036902A3 (sl) |
JP (2) | JP4463552B2 (sl) |
KR (3) | KR101063679B1 (sl) |
CN (1) | CN1247568C (sl) |
AP (1) | AP1818A (sl) |
AR (1) | AR038786A1 (sl) |
AT (1) | ATE420083T1 (sl) |
AU (1) | AU2002329397B2 (sl) |
BR (1) | BR0212468A (sl) |
CA (1) | CA2458632C (sl) |
CY (1) | CY1109449T1 (sl) |
DE (1) | DE60230773D1 (sl) |
DK (1) | DK1425277T3 (sl) |
EA (1) | EA007731B1 (sl) |
ES (1) | ES2316607T3 (sl) |
HK (1) | HK1066534A1 (sl) |
HU (1) | HUP0401923A3 (sl) |
IL (2) | IL160755A0 (sl) |
MA (1) | MA26216A1 (sl) |
MX (1) | MXPA04002379A (sl) |
MY (1) | MY138086A (sl) |
NO (3) | NO327009B1 (sl) |
NZ (1) | NZ531137A (sl) |
OA (1) | OA12659A (sl) |
PE (1) | PE20030417A1 (sl) |
PL (1) | PL213639B1 (sl) |
PT (1) | PT1425277E (sl) |
SI (1) | SI1425277T1 (sl) |
TW (1) | TWI283665B (sl) |
UY (1) | UY27446A1 (sl) |
WO (1) | WO2003022809A2 (sl) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY138086A (en) | 2001-09-13 | 2009-04-30 | Smithkline Beecham Plc | Novel urea derivative as vanilloid receptor-1 antagonist |
PT1472225E (pt) | 2002-02-01 | 2010-07-30 | Euro Celtique Sa | 2-piperazina-piridinas uteis para tratar a dor |
DE60325834D1 (de) * | 2002-02-20 | 2009-03-05 | Abbott Lab | Kondensierte azabicyclischeverbindungen als inhibitoren des vanilloid-rezeptors 1 (vr1) |
US7074805B2 (en) | 2002-02-20 | 2006-07-11 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US6974818B2 (en) | 2002-03-01 | 2005-12-13 | Euro-Celtique S.A. | 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain |
EP1556354B1 (en) | 2002-06-28 | 2008-01-23 | Euro-Celtique S.A. | Therapeutic piperazine derivates useful for treating pain |
US7262194B2 (en) | 2002-07-26 | 2007-08-28 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
GB0221157D0 (en) * | 2002-09-12 | 2002-10-23 | Glaxo Group Ltd | Novel treatment |
WO2004024710A1 (en) * | 2002-09-13 | 2004-03-25 | Glaxo Group Limited | Urea compounds active as vanilloid receptor antagonists for the treatment of pain |
US7157462B2 (en) | 2002-09-24 | 2007-01-02 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
CA2508618C (en) | 2002-12-06 | 2012-02-21 | Bayer Healthcare Ag | Tetrahydro-naphthalene derivatives |
GB0229808D0 (en) * | 2002-12-20 | 2003-01-29 | Glaxo Group Ltd | Novel compositions |
US6933311B2 (en) * | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
JP2006519826A (ja) | 2003-03-06 | 2006-08-31 | グラクソ グループ リミテッド | 疼痛治療のための複素環式尿素誘導体 |
EP1601665A2 (en) | 2003-03-07 | 2005-12-07 | Glaxo Group Limited | Urea derivatives |
GB0305426D0 (en) | 2003-03-08 | 2003-04-16 | Glaxo Group Ltd | Novel compounds |
SE0301446D0 (sv) | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
ATE556067T1 (de) | 2003-05-20 | 2012-05-15 | Ajinomoto Kk | Modulatoren des vanilloid rezeptors |
EP1493438A1 (en) * | 2003-07-03 | 2005-01-05 | Bayer HealthCare AG | Vanilloid receptor (VR) inhibitors for treatment of Human Immunodeficiency Virus (HIV)-mediated pain states |
GB0319151D0 (en) * | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Novel compounds |
GB0319150D0 (en) | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Novel compounds |
JP4833069B2 (ja) * | 2003-10-01 | 2011-12-07 | ゼンション・リミテッド | テトラヒドロ−ナフタレンおよび尿素誘導体 |
EP1679296A4 (en) | 2003-10-14 | 2007-12-26 | Ajinomoto Kk | DERIVE ETHERE |
JP2007509846A (ja) * | 2003-10-15 | 2007-04-19 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | テトラヒドロ−ナフタレンおよび尿素誘導体 |
CA2545109A1 (en) | 2003-11-08 | 2005-05-19 | Bayer Healthcare Ag | Tetrahydro-quinolinylurea derivatives |
EP1736465A4 (en) | 2004-03-31 | 2009-06-17 | Ajinomoto Kk | ANILINE DERIVATIVES |
WO2006002361A2 (en) | 2004-06-24 | 2006-01-05 | Incyte Corporation | 2-methylpropanamides and their use as pharmaceuticals |
WO2006007851A2 (en) | 2004-07-19 | 2006-01-26 | Novo Nordisk A/S | Capsaicin inhibitors for treating obesity and-related disorders |
KR20060087386A (ko) | 2005-01-28 | 2006-08-02 | 주식회사 대웅제약 | 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물 |
WO2006098554A1 (en) * | 2005-03-16 | 2006-09-21 | Amorepacific Corporation | Novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and a pharmaceutical composition containing the same |
WO2007046867A2 (en) * | 2005-05-19 | 2007-04-26 | Xenon Pharmaceuticals Inc. | Piperidine derivatives and their uses as therapeutic agents |
UY30048A1 (es) | 2005-12-23 | 2007-07-31 | Astrazeneca Ab | Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones |
EP1889830A1 (en) * | 2006-07-10 | 2008-02-20 | Pharmeste S.r.l. | Biarylcarboxyarylamides as vanilloid-1 receptor modulators |
EP1882687A1 (en) * | 2006-07-27 | 2008-01-30 | Amorepacific Corporation | Heterocyclic compounds useful as vanilloid receptor antagonists and pharmaceutical compositions containing the same |
JP5254228B2 (ja) * | 2006-07-27 | 2013-08-07 | 株式會社アモーレパシフィック | バニロイド受容体アンタゴニストとしての、新規化合物、その異性体またはその薬学的に許容される塩;並びにそれを含む医薬組成物 |
TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
MX2009002018A (es) | 2006-08-25 | 2009-03-05 | Abbott Lab | Derivados de indazol que inhiben vanilloide-1 potencial de receptor pasajero (trpv1) y usos de los mismos. |
EP2134678A2 (en) | 2006-12-20 | 2009-12-23 | Abbott Laboratories | N-(5, 6, 7, 8-tetrahydronaphthalen-1-yl) urea derivatives and related compounds as trpv1 vanilloid receptor antagonists for the treatment of pain |
EP2323989A4 (en) | 2008-03-20 | 2011-06-22 | Abbott Lab | METHODS FOR PREPARING AGENTS FOR THE CENTRAL NERVOUS SYSTEM THAT ARE TRPV1 ANTAGONISTS |
CN101983197B (zh) | 2008-04-18 | 2015-04-22 | 大熊制药株式会社 | 新型苯并噁嗪苯并咪唑衍生物、含有该衍生物的药物组合物及其用途 |
KR101409651B1 (ko) | 2008-05-07 | 2014-06-18 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 시클릭 아민-1-카르복실산 에스테르 유도체 및 그것을 함유하는 약제학적 조성물 |
WO2010026128A1 (en) * | 2008-09-02 | 2010-03-11 | Glaxo Group Limited | N-(3-methyl-5-isoquinolinyl)-n'-((3r)-1-[5-(trifluoromethyl)-2-pyridinyl]-3-pyrrolidinyl) urea for the treatment of rhinitis |
WO2010026129A1 (en) * | 2008-09-02 | 2010-03-11 | Glaxo Group Limited | The trpvl antagonist sb-705498 for treating rhinitis |
JP2013028536A (ja) * | 2009-11-11 | 2013-02-07 | Dainippon Sumitomo Pharma Co Ltd | 環状アミン−1−カルボン酸エステル誘導体およびそれを含有する医薬組成物 |
WO2012045729A1 (en) | 2010-10-05 | 2012-04-12 | Glaxo Group Limited | Imidazo [1, 2 -a] pyridine and pyrazolo [1, 5 -a] pyridine derivatives as trpv1 antagonists |
KR101293384B1 (ko) | 2010-10-13 | 2013-08-05 | 주식회사 대웅제약 | 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도 |
WO2012072512A1 (en) | 2010-11-29 | 2012-06-07 | Glaxo Group Limited | N-cyclobutyl-imidazopyridine or -pyrazolopyridine carboxamides as trpv1 antagonists |
GB201101517D0 (en) * | 2011-01-28 | 2011-03-16 | Proximagen Ltd | Receptor antagonists |
WO2012139963A1 (en) | 2011-04-11 | 2012-10-18 | Glaxo Group Limited | N- cyclobutyl - imidazopyridine - methylamine as trpv1 antagonists |
DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3424761A (en) * | 1966-03-07 | 1969-01-28 | Robins Co Inc A H | 3-ureidopyrrolidines |
US3424760A (en) * | 1966-03-07 | 1969-01-28 | Robins Co Inc A H | 3-ureidopyrrolidines |
GB1460389A (en) * | 1974-07-25 | 1977-01-06 | Pfizer Ltd | 4-substituted quinazoline cardiac stimulants |
DE68918991T2 (de) | 1988-06-17 | 1995-04-27 | Procter & Gamble | Anwendung von Vanillin-Derivaten zur Herstellung eines Arzneimittels zur Behandlung von Herpes simplex-Infektion. |
HU206082B (en) | 1988-12-23 | 1992-08-28 | Sandoz Ag | Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds |
CA2017383A1 (en) | 1989-06-08 | 1990-12-08 | Raymond R. Martodam | Use of vanilloids for the treatment of respiratory diseases or disorders |
WO1992009285A1 (en) | 1990-11-27 | 1992-06-11 | The Procter & Gamble Company | Combinations of vanilloid compounds and phosphonate antiviral compounds for treatment of herpes infections |
US5149704A (en) | 1991-05-03 | 1992-09-22 | Abbott Laboratories | Platelet activating antagonists |
CA2197364A1 (en) * | 1996-02-15 | 1997-08-16 | Toshikazu Suzuki | Phenol compound and process for preparing the same |
AU8270898A (en) * | 1997-06-26 | 1999-01-19 | Eli Lilly And Company | Antithrombotic agents |
EP1019045B1 (en) * | 1997-06-26 | 2005-06-08 | Eli Lilly And Company | Antithrombotic agents |
JP2000080085A (ja) | 1997-09-01 | 2000-03-21 | Kyorin Pharmaceut Co Ltd | 6,7−非対称ジ置換キノキサリンカルボン酸誘導体とその付加塩及びそれらの製造方法 |
ATE312812T1 (de) | 1999-02-22 | 2005-12-15 | Pacific Corp | Vanilloid-analoge die resiniferatoxin- pharmacophore enthalten als wirksame vanilloid rezeptor agonisten und analgetika, zusammensetzungen und ihre verwendung |
DK1165516T3 (da) | 1999-03-12 | 2005-01-31 | Boehringer Ingelheim Pharma | Heterocyklisk urinstof og beslægtede forbindelser, der er nyttige som antiinflammatoriske midler |
AU1201401A (en) | 1999-10-15 | 2001-04-30 | Du Pont Pharmaceuticals Company | Benzylcycloalkyl amines as modulators of chemokine receptor activity |
CA2415606A1 (en) | 2000-07-20 | 2002-01-31 | Neurogen Corporation | Capsaicin receptor ligands |
WO2002016319A1 (en) | 2000-08-21 | 2002-02-28 | Pacific Corporation | Novel thiourea compounds and the pharmaceutical compositions containing the same |
AU2001278821A1 (en) | 2000-08-21 | 2002-03-04 | Pacific Corporation | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same |
JP5001505B2 (ja) | 2000-08-21 | 2012-08-15 | 株式會社アモーレパシフィック | 新規チオウレア誘導体およびこれを含有する薬学的組成物 |
JP2002080073A (ja) | 2000-09-07 | 2002-03-19 | Kyokuto Kobunshi Kk | 電子レンジ用自動開孔袋 |
JP2002088073A (ja) * | 2000-09-08 | 2002-03-27 | Yamanouchi Pharmaceut Co Ltd | 抗アンドロゲン剤 |
GB0110901D0 (en) | 2001-05-02 | 2001-06-27 | Smithkline Beecham Plc | Novel Compounds |
MY138086A (en) | 2001-09-13 | 2009-04-30 | Smithkline Beecham Plc | Novel urea derivative as vanilloid receptor-1 antagonist |
MXPA05000081A (es) * | 2002-06-27 | 2005-04-11 | Schering Ag | Quinolinas sustituidas antagonistas del receptor ccr5. |
WO2004024710A1 (en) * | 2002-09-13 | 2004-03-25 | Glaxo Group Limited | Urea compounds active as vanilloid receptor antagonists for the treatment of pain |
GB0229808D0 (en) | 2002-12-20 | 2003-01-29 | Glaxo Group Ltd | Novel compositions |
EP1740557A1 (en) | 2004-04-20 | 2007-01-10 | Bayer HealthCare AG | Urea derivatives as antagonists of the vanilloid receptor (vr1) |
-
2002
- 2002-09-11 MY MYPI20023391A patent/MY138086A/en unknown
- 2002-09-11 TW TW091120671A patent/TWI283665B/zh not_active IP Right Cessation
- 2002-09-11 PE PE2002000895A patent/PE20030417A1/es not_active Application Discontinuation
- 2002-09-12 AR ARP020103454A patent/AR038786A1/es active IP Right Grant
- 2002-09-12 UY UY27446A patent/UY27446A1/es not_active Application Discontinuation
- 2002-09-13 AP APAP/P/2004/002982A patent/AP1818A/en active
- 2002-09-13 JP JP2003526885A patent/JP4463552B2/ja not_active Expired - Fee Related
- 2002-09-13 PL PL369026A patent/PL213639B1/pl not_active IP Right Cessation
- 2002-09-13 AT AT02765023T patent/ATE420083T1/de active
- 2002-09-13 CN CNB028177177A patent/CN1247568C/zh not_active Expired - Fee Related
- 2002-09-13 IL IL16075502A patent/IL160755A0/xx unknown
- 2002-09-13 KR KR1020047003680A patent/KR101063679B1/ko not_active IP Right Cessation
- 2002-09-13 EA EA200400432A patent/EA007731B1/ru not_active IP Right Cessation
- 2002-09-13 KR KR1020097003812A patent/KR100955967B1/ko not_active IP Right Cessation
- 2002-09-13 SI SI200230792T patent/SI1425277T1/sl unknown
- 2002-09-13 EP EP08172882A patent/EP2036902A3/en not_active Withdrawn
- 2002-09-13 US US10/489,277 patent/US8063078B2/en not_active Expired - Fee Related
- 2002-09-13 BR BR0212468-8A patent/BR0212468A/pt not_active IP Right Cessation
- 2002-09-13 NZ NZ531137A patent/NZ531137A/en not_active IP Right Cessation
- 2002-09-13 DE DE60230773T patent/DE60230773D1/de not_active Expired - Lifetime
- 2002-09-13 ES ES02765023T patent/ES2316607T3/es not_active Expired - Lifetime
- 2002-09-13 WO PCT/GB2002/004206 patent/WO2003022809A2/en active Application Filing
- 2002-09-13 PT PT02765023T patent/PT1425277E/pt unknown
- 2002-09-13 KR KR1020107014626A patent/KR20100082390A/ko not_active Application Discontinuation
- 2002-09-13 HU HU0401923A patent/HUP0401923A3/hu unknown
- 2002-09-13 MX MXPA04002379A patent/MXPA04002379A/es active IP Right Grant
- 2002-09-13 EP EP02765023A patent/EP1425277B8/en not_active Expired - Lifetime
- 2002-09-13 DK DK02765023T patent/DK1425277T3/da active
- 2002-09-13 OA OA1200400070A patent/OA12659A/en unknown
- 2002-09-13 CA CA2458632A patent/CA2458632C/en not_active Expired - Fee Related
- 2002-09-13 AU AU2002329397A patent/AU2002329397B2/en not_active Ceased
- 2002-09-13 EP EP10179466A patent/EP2298757A3/en not_active Withdrawn
-
2004
- 2004-03-04 IL IL160755A patent/IL160755A/en not_active IP Right Cessation
- 2004-03-10 NO NO20041003A patent/NO327009B1/no not_active IP Right Cessation
- 2004-03-12 MA MA27573A patent/MA26216A1/fr unknown
- 2004-11-30 HK HK04109442.1A patent/HK1066534A1/xx unknown
-
2008
- 2008-12-04 NO NO20085077A patent/NO20085077L/no not_active Application Discontinuation
- 2008-12-04 NO NO20085078A patent/NO20085078L/no unknown
-
2009
- 2009-03-19 CY CY20091100306T patent/CY1109449T1/el unknown
- 2009-12-08 JP JP2009278584A patent/JP2010100632A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1425277T3 (da) | Urinstof-forbindelser aktive som vanilloid-receptor-antagonister til behandling af smerte | |
AU2003270199A1 (en) | Urea compounds active as vanilloid receptor antagonists for the treatment of pain | |
DK1208095T3 (da) | Dibenzopyraner som glucocorticoidreceptorantagonister til behandling af diabetes | |
NO20034122L (no) | Sammensmeltede pyridinderivater for anvendelse som vanilloidreseptorantagonister for behandling av smerte | |
DK1505974T3 (da) | Anvendelse af forbindelser, der er effektive som selektive opiatreceptormodulatorer | |
DK1485127T3 (da) | Anvendelse af midler til behandling af inflammation | |
DK1339335T3 (da) | Indretning til fiksering af knogler, især af hvirvellegemer i forhold til hinanden | |
DE60325025D1 (de) | Modulatoren des vanilloidrezeptors | |
NO20041339L (no) | Spiro-hydantoin-forbindelser anvendelige som anti-inflammatoriske midler | |
DK1339678T3 (da) | Selektive agonister til EP4-receptor til behandling af osteoporose | |
ATE533743T1 (de) | Harnstoffderivate von aminotetralin als modulatoren des vanilloid-rezeptors vr1 | |
NO20032861D0 (no) | Heteroarylurea nevropeptid YY5-reseptorantagonister | |
DE60317967D1 (de) | Umhüllte feste Darreichungsform | |
NO20055238D0 (no) | Kondenserte N-heterocykliske forbindelser og deres anvendelse som CRF-reseptorantagonister | |
DE50309032D1 (de) | Fungizide wirkstoffkombinationen | |
DK2289514T5 (da) | Pramipexol-doseringsform til anvendelse én gang dagligt | |
NO20030471D0 (no) | Karboksamidforbindelser og deres anvendelse som antagonister for en 11CBY-reseptor | |
DK1862458T3 (da) | Terapeutiske midler anvendelige til smertebehandling | |
DK1803718T3 (da) | 4-Tetrazolyl-4-phenylpiperidin-derivater til behandling af smerter | |
DK1282616T3 (da) | Hydroxyphenylpiperidin-4-ylidenmethylbenzamidderivater til behandling af smerter | |
DK1501806T3 (da) | Præparater til topisk applikation af antiandrogent virksomme substanser | |
DE50213466D1 (de) | Fungizide wirkstoffkombinationen | |
ATE492535T1 (de) | 4-piperidinylalkylamin-derivate, antagonisten von muscarinrezeptoren | |
DE60224221D1 (de) | Aminotetralinderivate, antagonisten von muscarinrezeptoren | |
NO20044373L (no) | Azetidinderivater som CCR-3-reseptorantagonister |