SI1425277T1 - Seäśninske spojine, aktivne kot vaniloidni receptorski antagonisti za zdravljenje boleäśine - Google Patents
Seäśninske spojine, aktivne kot vaniloidni receptorski antagonisti za zdravljenje boleäśineInfo
- Publication number
- SI1425277T1 SI1425277T1 SI200230792T SI200230792T SI1425277T1 SI 1425277 T1 SI1425277 T1 SI 1425277T1 SI 200230792 T SI200230792 T SI 200230792T SI 200230792 T SI200230792 T SI 200230792T SI 1425277 T1 SI1425277 T1 SI 1425277T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pain
- urea
- treatment
- receptor antagonists
- vanilloid receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0122156A GB0122156D0 (en) | 2001-09-13 | 2001-09-13 | Novel compounds |
GB0130503A GB0130503D0 (en) | 2001-12-20 | 2001-12-20 | Novel compounds |
GB0130505A GB0130505D0 (en) | 2001-12-20 | 2001-12-20 | Novel compounds |
GB0130547A GB0130547D0 (en) | 2001-12-20 | 2001-12-20 | Novel compounds |
EP02765023A EP1425277B8 (en) | 2001-09-13 | 2002-09-13 | Urea-compounds active as vanilloid receptor antagonists for the treatment of pain |
PCT/GB2002/004206 WO2003022809A2 (en) | 2001-09-13 | 2002-09-13 | Urea-compounds active as vanilloid receptor antagonists for the treatment of pain |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1425277T1 true SI1425277T1 (sl) | 2009-04-30 |
Family
ID=27447989
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200230792T SI1425277T1 (sl) | 2001-09-13 | 2002-09-13 | Seäśninske spojine, aktivne kot vaniloidni receptorski antagonisti za zdravljenje boleäśine |
Country Status (32)
Country | Link |
---|---|
US (1) | US8063078B2 (sl) |
EP (3) | EP1425277B8 (sl) |
JP (2) | JP4463552B2 (sl) |
KR (3) | KR101063679B1 (sl) |
CN (1) | CN1247568C (sl) |
AP (1) | AP1818A (sl) |
AR (1) | AR038786A1 (sl) |
AT (1) | ATE420083T1 (sl) |
AU (1) | AU2002329397B2 (sl) |
BR (1) | BR0212468A (sl) |
CA (1) | CA2458632C (sl) |
CY (1) | CY1109449T1 (sl) |
DE (1) | DE60230773D1 (sl) |
DK (1) | DK1425277T3 (sl) |
EA (1) | EA007731B1 (sl) |
ES (1) | ES2316607T3 (sl) |
HK (1) | HK1066534A1 (sl) |
HU (1) | HUP0401923A3 (sl) |
IL (2) | IL160755A0 (sl) |
MA (1) | MA26216A1 (sl) |
MX (1) | MXPA04002379A (sl) |
MY (1) | MY138086A (sl) |
NO (3) | NO327009B1 (sl) |
NZ (1) | NZ531137A (sl) |
OA (1) | OA12659A (sl) |
PE (1) | PE20030417A1 (sl) |
PL (1) | PL213639B1 (sl) |
PT (1) | PT1425277E (sl) |
SI (1) | SI1425277T1 (sl) |
TW (1) | TWI283665B (sl) |
UY (1) | UY27446A1 (sl) |
WO (1) | WO2003022809A2 (sl) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY138086A (en) * | 2001-09-13 | 2009-04-30 | Smithkline Beecham Plc | Novel urea derivative as vanilloid receptor-1 antagonist |
DE60332316D1 (de) | 2002-02-01 | 2010-06-10 | Euro Celtique Sa | 2-piperazinpyridine für die schmerzbehandlung |
US7074805B2 (en) | 2002-02-20 | 2006-07-11 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
WO2003070247A1 (en) * | 2002-02-20 | 2003-08-28 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor |
US6974818B2 (en) | 2002-03-01 | 2005-12-13 | Euro-Celtique S.A. | 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain |
CN100457735C (zh) | 2002-06-28 | 2009-02-04 | 欧洲凯尔特公司 | 用于治疗疼痛的治疗剂 |
US7262194B2 (en) | 2002-07-26 | 2007-08-28 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
GB0221157D0 (en) * | 2002-09-12 | 2002-10-23 | Glaxo Group Ltd | Novel treatment |
WO2004024710A1 (en) * | 2002-09-13 | 2004-03-25 | Glaxo Group Limited | Urea compounds active as vanilloid receptor antagonists for the treatment of pain |
US7157462B2 (en) | 2002-09-24 | 2007-01-02 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
AU2003294748A1 (en) | 2002-12-06 | 2004-06-30 | Bayer Healthcare Ag | Tetrahydro-naphthalene derivatives |
GB0229808D0 (en) | 2002-12-20 | 2003-01-29 | Glaxo Group Ltd | Novel compositions |
US6933311B2 (en) * | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US7528151B2 (en) | 2003-03-06 | 2009-05-05 | Glaxo Group Limited | Heterocyclic urea derivatives for the treatment of pain |
EP1601665A2 (en) * | 2003-03-07 | 2005-12-07 | Glaxo Group Limited | Urea derivatives |
GB0305426D0 (en) * | 2003-03-08 | 2003-04-16 | Glaxo Group Ltd | Novel compounds |
SE0301446D0 (sv) | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
JP5279987B2 (ja) | 2003-05-20 | 2013-09-04 | 味の素株式会社 | アミド誘導体 |
EP1493438A1 (en) * | 2003-07-03 | 2005-01-05 | Bayer HealthCare AG | Vanilloid receptor (VR) inhibitors for treatment of Human Immunodeficiency Virus (HIV)-mediated pain states |
GB0319151D0 (en) * | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Novel compounds |
GB0319150D0 (en) | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Novel compounds |
EP2048132B1 (en) | 2003-10-01 | 2011-04-13 | Xention Limited | Tetrahydro-naphthalene and urea derivatives |
JP4935073B2 (ja) | 2003-10-14 | 2012-05-23 | 味の素株式会社 | エーテル誘導体 |
WO2005040100A1 (en) * | 2003-10-15 | 2005-05-06 | Bayer Healthcare Ag | Tetrahydro-naphthalene and urea derivatives |
EP1685112B1 (en) | 2003-11-08 | 2011-07-20 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydro-quinolinylurea derivatives as vr1 antagonists |
EP1736465A4 (en) * | 2004-03-31 | 2009-06-17 | Ajinomoto Kk | ANILINE DERIVATIVES |
JP2008504280A (ja) | 2004-06-24 | 2008-02-14 | インサイト・コーポレイション | 2−メチルプロパンアミドおよびその医薬としての使用 |
EP1771162B1 (en) | 2004-07-19 | 2013-06-05 | Xenia Pharma | Capsaicin inhibitors for the treatment of obesity-related disorders |
KR20060087386A (ko) | 2005-01-28 | 2006-08-02 | 주식회사 대웅제약 | 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물 |
WO2006098554A1 (en) * | 2005-03-16 | 2006-09-21 | Amorepacific Corporation | Novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and a pharmaceutical composition containing the same |
WO2007046867A2 (en) * | 2005-05-19 | 2007-04-26 | Xenon Pharmaceuticals Inc. | Piperidine derivatives and their uses as therapeutic agents |
TW200736227A (en) | 2005-12-23 | 2007-10-01 | Astrazeneca Ab | New compounds III |
EP1889830A1 (en) * | 2006-07-10 | 2008-02-20 | Pharmeste S.r.l. | Biarylcarboxyarylamides as vanilloid-1 receptor modulators |
EP2054411B1 (en) * | 2006-07-27 | 2014-08-20 | Amorepacific Corporation | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
EP1882687A1 (en) * | 2006-07-27 | 2008-01-30 | Amorepacific Corporation | Heterocyclic compounds useful as vanilloid receptor antagonists and pharmaceutical compositions containing the same |
TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
MX2009002018A (es) | 2006-08-25 | 2009-03-05 | Abbott Lab | Derivados de indazol que inhiben vanilloide-1 potencial de receptor pasajero (trpv1) y usos de los mismos. |
CA2672196A1 (en) | 2006-12-20 | 2008-07-03 | Abbott Laboratories | Antagonists of the trpv1 receptor and uses thereof |
CA2719018A1 (en) | 2008-03-20 | 2009-09-24 | Abbott Laboratories | Methods for making central nervous system agents that are trpv1 antagonists |
MY152022A (en) | 2008-04-18 | 2014-08-15 | Dae Woong Pharma | A novel benzoxazine benzimidazole derivatives, a pharmaceutical composition comprising the same, and a use thereof |
WO2009136625A1 (ja) * | 2008-05-07 | 2009-11-12 | 大日本住友製薬株式会社 | 環状アミン-1-カルボン酸エステル誘導体およびそれを含有する医薬組成物 |
WO2010026129A1 (en) * | 2008-09-02 | 2010-03-11 | Glaxo Group Limited | The trpvl antagonist sb-705498 for treating rhinitis |
WO2010026128A1 (en) * | 2008-09-02 | 2010-03-11 | Glaxo Group Limited | N-(3-methyl-5-isoquinolinyl)-n'-((3r)-1-[5-(trifluoromethyl)-2-pyridinyl]-3-pyrrolidinyl) urea for the treatment of rhinitis |
JP2013028536A (ja) * | 2009-11-11 | 2013-02-07 | Dainippon Sumitomo Pharma Co Ltd | 環状アミン−1−カルボン酸エステル誘導体およびそれを含有する医薬組成物 |
WO2012045729A1 (en) | 2010-10-05 | 2012-04-12 | Glaxo Group Limited | Imidazo [1, 2 -a] pyridine and pyrazolo [1, 5 -a] pyridine derivatives as trpv1 antagonists |
KR101293384B1 (ko) | 2010-10-13 | 2013-08-05 | 주식회사 대웅제약 | 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도 |
WO2012072512A1 (en) | 2010-11-29 | 2012-06-07 | Glaxo Group Limited | N-cyclobutyl-imidazopyridine or -pyrazolopyridine carboxamides as trpv1 antagonists |
GB201101517D0 (en) * | 2011-01-28 | 2011-03-16 | Proximagen Ltd | Receptor antagonists |
JP2014510768A (ja) | 2011-04-11 | 2014-05-01 | グラクソ グループ リミテッド | Trpv1アンタゴニストとしてのn−シクロブチルイミダゾピリジンメチルアミン |
DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3424760A (en) * | 1966-03-07 | 1969-01-28 | Robins Co Inc A H | 3-ureidopyrrolidines |
US3424761A (en) * | 1966-03-07 | 1969-01-28 | Robins Co Inc A H | 3-ureidopyrrolidines |
GB1460389A (en) | 1974-07-25 | 1977-01-06 | Pfizer Ltd | 4-substituted quinazoline cardiac stimulants |
ATE113205T1 (de) | 1988-06-17 | 1994-11-15 | Procter & Gamble | Anwendung von vanillin-derivaten zur herstellung eines arzneimittels zur behandlung von herpes simplex-infektion. |
HU206082B (en) | 1988-12-23 | 1992-08-28 | Sandoz Ag | Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds |
CA2017383A1 (en) | 1989-06-08 | 1990-12-08 | Raymond R. Martodam | Use of vanilloids for the treatment of respiratory diseases or disorders |
AU9079491A (en) | 1990-11-27 | 1992-06-25 | Procter & Gamble Company, The | Combinations of vanilloid compounds and phosphonate antiviral compounds for treatment of herpes infections |
US5149704A (en) * | 1991-05-03 | 1992-09-22 | Abbott Laboratories | Platelet activating antagonists |
CA2197364A1 (en) * | 1996-02-15 | 1997-08-16 | Toshikazu Suzuki | Phenol compound and process for preparing the same |
IL133621A0 (en) * | 1997-06-26 | 2001-04-30 | Lilly Co Eli | Antithrombotic agents |
AU8270298A (en) * | 1997-06-26 | 1999-01-19 | Eli Lilly And Company | Antithrombotic agents |
JP2000080085A (ja) * | 1997-09-01 | 2000-03-21 | Kyorin Pharmaceut Co Ltd | 6,7−非対称ジ置換キノキサリンカルボン酸誘導体とその付加塩及びそれらの製造方法 |
DE60024785T2 (de) | 1999-02-22 | 2006-09-14 | Amorepacific Corp. | Vanilloid-analoge die resiniferatoxin-pharmacophore enthalten als wirksame vanilloid rezeptor agonisten und analgetika, zusammensetzungen und ihre verwendung |
NZ528846A (en) | 1999-03-12 | 2005-05-27 | Boehringer Ingelheim Pharma | Compounds useful as anti-inflammatory agents |
JP2003512349A (ja) | 1999-10-15 | 2003-04-02 | デュポン ファーマシューティカルズ カンパニー | ケモカイン受容体活性のモジュレーターとしてのベンジルシクロアルキルアミン |
BR0112631A (pt) | 2000-07-20 | 2003-09-23 | Neurogen Corp | Composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, pacote, métodos de reduzir a condutáncia de cálcio de um receptor de capsaicina e de tratar um mamìfero e uso de um composto |
US7067553B2 (en) | 2000-08-21 | 2006-06-27 | Pacific Corporation | Thiourea compounds and the pharmaceutical compositions containing the same |
JP5001505B2 (ja) | 2000-08-21 | 2012-08-15 | 株式會社アモーレパシフィック | 新規チオウレア誘導体およびこれを含有する薬学的組成物 |
US20030203944A1 (en) | 2000-08-21 | 2003-10-30 | Suh Young Ger | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same |
JP2002080073A (ja) | 2000-09-07 | 2002-03-19 | Kyokuto Kobunshi Kk | 電子レンジ用自動開孔袋 |
JP2002088073A (ja) * | 2000-09-08 | 2002-03-27 | Yamanouchi Pharmaceut Co Ltd | 抗アンドロゲン剤 |
GB0110901D0 (en) | 2001-05-02 | 2001-06-27 | Smithkline Beecham Plc | Novel Compounds |
MY138086A (en) * | 2001-09-13 | 2009-04-30 | Smithkline Beecham Plc | Novel urea derivative as vanilloid receptor-1 antagonist |
AU2003247772A1 (en) * | 2002-06-27 | 2004-01-19 | Schering Aktiengesellschaft | Substituted quinoline ccr5 receptor antagonists |
WO2004024710A1 (en) | 2002-09-13 | 2004-03-25 | Glaxo Group Limited | Urea compounds active as vanilloid receptor antagonists for the treatment of pain |
GB0229808D0 (en) | 2002-12-20 | 2003-01-29 | Glaxo Group Ltd | Novel compositions |
EP1740557A1 (en) | 2004-04-20 | 2007-01-10 | Bayer HealthCare AG | Urea derivatives as antagonists of the vanilloid receptor (vr1) |
-
2002
- 2002-09-11 MY MYPI20023391A patent/MY138086A/en unknown
- 2002-09-11 TW TW091120671A patent/TWI283665B/zh not_active IP Right Cessation
- 2002-09-11 PE PE2002000895A patent/PE20030417A1/es not_active Application Discontinuation
- 2002-09-12 UY UY27446A patent/UY27446A1/es not_active Application Discontinuation
- 2002-09-12 AR ARP020103454A patent/AR038786A1/es active IP Right Grant
- 2002-09-13 PT PT02765023T patent/PT1425277E/pt unknown
- 2002-09-13 HU HU0401923A patent/HUP0401923A3/hu unknown
- 2002-09-13 US US10/489,277 patent/US8063078B2/en not_active Expired - Fee Related
- 2002-09-13 OA OA1200400070A patent/OA12659A/en unknown
- 2002-09-13 PL PL369026A patent/PL213639B1/pl not_active IP Right Cessation
- 2002-09-13 DK DK02765023T patent/DK1425277T3/da active
- 2002-09-13 AU AU2002329397A patent/AU2002329397B2/en not_active Ceased
- 2002-09-13 EA EA200400432A patent/EA007731B1/ru not_active IP Right Cessation
- 2002-09-13 KR KR1020047003680A patent/KR101063679B1/ko not_active IP Right Cessation
- 2002-09-13 WO PCT/GB2002/004206 patent/WO2003022809A2/en active Application Filing
- 2002-09-13 NZ NZ531137A patent/NZ531137A/en not_active IP Right Cessation
- 2002-09-13 EP EP02765023A patent/EP1425277B8/en not_active Expired - Lifetime
- 2002-09-13 SI SI200230792T patent/SI1425277T1/sl unknown
- 2002-09-13 EP EP10179466A patent/EP2298757A3/en not_active Withdrawn
- 2002-09-13 KR KR1020097003812A patent/KR100955967B1/ko not_active IP Right Cessation
- 2002-09-13 ES ES02765023T patent/ES2316607T3/es not_active Expired - Lifetime
- 2002-09-13 BR BR0212468-8A patent/BR0212468A/pt not_active IP Right Cessation
- 2002-09-13 EP EP08172882A patent/EP2036902A3/en not_active Withdrawn
- 2002-09-13 DE DE60230773T patent/DE60230773D1/de not_active Expired - Lifetime
- 2002-09-13 KR KR1020107014626A patent/KR20100082390A/ko not_active Application Discontinuation
- 2002-09-13 MX MXPA04002379A patent/MXPA04002379A/es active IP Right Grant
- 2002-09-13 CA CA2458632A patent/CA2458632C/en not_active Expired - Fee Related
- 2002-09-13 JP JP2003526885A patent/JP4463552B2/ja not_active Expired - Fee Related
- 2002-09-13 AT AT02765023T patent/ATE420083T1/de active
- 2002-09-13 CN CNB028177177A patent/CN1247568C/zh not_active Expired - Fee Related
- 2002-09-13 AP APAP/P/2004/002982A patent/AP1818A/en active
- 2002-09-13 IL IL16075502A patent/IL160755A0/xx unknown
-
2004
- 2004-03-04 IL IL160755A patent/IL160755A/en not_active IP Right Cessation
- 2004-03-10 NO NO20041003A patent/NO327009B1/no not_active IP Right Cessation
- 2004-03-12 MA MA27573A patent/MA26216A1/fr unknown
- 2004-11-30 HK HK04109442.1A patent/HK1066534A1/xx unknown
-
2008
- 2008-12-04 NO NO20085077A patent/NO20085077L/no not_active Application Discontinuation
- 2008-12-04 NO NO20085078A patent/NO20085078L/no unknown
-
2009
- 2009-03-19 CY CY20091100306T patent/CY1109449T1/el unknown
- 2009-12-08 JP JP2009278584A patent/JP2010100632A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1066534A1 (en) | Urea-compounds active as vanilloid receptor antagonists for the treatment of pain | |
AU2003270199A1 (en) | Urea compounds active as vanilloid receptor antagonists for the treatment of pain | |
NO20034122L (no) | Sammensmeltede pyridinderivater for anvendelse som vanilloidreseptorantagonister for behandling av smerte | |
IL159344A0 (en) | Quinuclidines-substituted-multicyclic-heteroaryls for the treatment of disease | |
IL161041A0 (en) | Mch antagonists for the treatment of obesity | |
HUP0300117A3 (en) | Use of interleukin-6 antagonists for the treatment of diseases characterised by high levels of aromatase | |
NO20042208L (no) | Vaginalt administrerte anti-dysrytmiske midler for behandling av bekkensmerter | |
IL147977A0 (en) | Substituted 1,5-dihydropyrrol-2-on derivatives as nmda receptor antagonists for the treatment of pain | |
AU2003290059A8 (en) | Use of cd137 antagonists for the treatment of tumors | |
IL157145A0 (en) | Use of dc23 antagonists for the treatment of neoplastic disorders | |
EP1399175A4 (en) | THERAPEUTIC USE OF RANK ANTAGONISTS | |
IL158829A0 (en) | Exothermic formulations for the treatment of ectoparasites | |
IL157593A0 (en) | Carbamate compounds for use in the treatment of pain | |
IL198759A (en) | Use of 3gal receptor antagonists to prepare medications to treat depression and / or anxiety | |
GB0213869D0 (en) | The treatment of pain | |
AU2002212895A1 (en) | N-type calcium channel antagonists for the treatment of pain | |
AU2003264297A1 (en) | Use of vanilloid receptor antagonists for the treatment of pain | |
EP1208101A4 (en) | VITRONECTIN RECEPTOR ANTAGONISTS USEFUL FOR THE TREATMENT OF VASCULAR ACCIDENTS | |
AU2002315522A1 (en) | Receptor agonists useful for the treatment of pain | |
GB9904252D0 (en) | Composition for the treatment of pain | |
AU2002316237A1 (en) | Use of the parathroid hormone-2 (pth2) receptor to screen for agents to treat pain | |
AU2002212896A1 (en) | N-type calcium channel antagonists for the treatment of pain | |
EP1451308A4 (en) | THERAPEUTIC USE OF AZIRIDINO COMPOUNDS | |
AU2003245995A8 (en) | Use of gaba-c receptor antagonists for the treatment of myopia | |
AU2002324407A1 (en) | N-type calcium channel antagonists for the treatment of pain |