DK135683B - Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzyl-pyrimidinderivater eller salte af disse forbindelser. - Google Patents
Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzyl-pyrimidinderivater eller salte af disse forbindelser.Info
- Publication number
- DK135683B DK135683B DK468374AA DK468374A DK135683B DK 135683 B DK135683 B DK 135683B DK 468374A A DK468374A A DK 468374AA DK 468374 A DK468374 A DK 468374A DK 135683 B DK135683 B DK 135683B
- Authority
- DK
- Denmark
- Prior art keywords
- diamino
- benzyl
- salts
- compounds
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK304476A DK304476A (da) | 1973-09-12 | 1976-07-05 | Benzylpyrimidiner, deres fremstilling og anvendelse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1305773A CH591456A5 (sv) | 1973-09-12 | 1973-09-12 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK468374A DK468374A (sv) | 1975-05-12 |
| DK135683B true DK135683B (da) | 1977-06-06 |
| DK135683C DK135683C (sv) | 1977-11-14 |
Family
ID=4388903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK468374AA DK135683B (da) | 1973-09-12 | 1974-09-04 | Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzyl-pyrimidinderivater eller salte af disse forbindelser. |
Country Status (28)
| Country | Link |
|---|---|
| JP (1) | JPS6042238B2 (sv) |
| AR (2) | AR207764A1 (sv) |
| AT (1) | AT338797B (sv) |
| BE (1) | BE819773A (sv) |
| BR (1) | BR7407614D0 (sv) |
| CA (1) | CA1037476A (sv) |
| CH (1) | CH591456A5 (sv) |
| CU (1) | CU34115A (sv) |
| DD (2) | DD116824A5 (sv) |
| DE (1) | DE2443682C2 (sv) |
| DK (1) | DK135683B (sv) |
| ES (7) | ES429949A1 (sv) |
| FI (1) | FI58638C (sv) |
| FR (1) | FR2242984B1 (sv) |
| GB (3) | GB1484483A (sv) |
| HK (1) | HK181A (sv) |
| HU (1) | HU170427B (sv) |
| IE (1) | IE40523B1 (sv) |
| IL (1) | IL45510A (sv) |
| LU (1) | LU70878A1 (sv) |
| NL (1) | NL155827B (sv) |
| NO (1) | NO140858C (sv) |
| PH (1) | PH10643A (sv) |
| PL (2) | PL99159B1 (sv) |
| SE (1) | SE419443B (sv) |
| SU (3) | SU577987A3 (sv) |
| YU (3) | YU217874A (sv) |
| ZA (1) | ZA745317B (sv) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4515948A (en) * | 1973-09-12 | 1985-05-07 | Hoffmann-La Roche Inc. | 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines |
| JPS5481278A (en) * | 1977-10-18 | 1979-06-28 | Wellcome Found | Manufacture of triiseccaminomethane |
| CH639273A5 (de) | 1978-09-12 | 1983-11-15 | Hoffmann La Roche | Diuretische mittel. |
| DE3250132C2 (de) * | 1981-11-09 | 1997-01-16 | Mallinckrodt Veterinary Inc | Verfahren zur Herstellung von 2,4-Diamino-5-benzyl-pyrimidinen und neue Zwischenprodukte des Verfahrens |
| FR2516081B1 (fr) * | 1981-11-09 | 1987-05-29 | Wellcome Found | Synthese de benzylpyrimidines et produits intermediaires pour cette synthese |
| GB2180836A (en) * | 1985-09-27 | 1987-04-08 | William James Stephen Barker | Sunscreen |
| JPH0431685Y2 (sv) * | 1987-06-01 | 1992-07-30 | ||
| US4900859A (en) * | 1987-12-03 | 1990-02-13 | Hoffman-La Roche Inc. | Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde |
| CA1300166C (en) * | 1987-12-03 | 1992-05-05 | Alfredo Guerrato | Process for the preparation of a benzoic acid ester |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1103931B (de) * | 1957-02-21 | 1961-04-06 | Wellcome Found | Verfahren zur Herstellung von 2, 4-Diamino-5-benzylpyrimidinderivaten |
| US3485840A (en) * | 1964-11-12 | 1969-12-23 | Hoffmann La Roche | 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes |
-
1973
- 1973-09-12 CH CH1305773A patent/CH591456A5/xx not_active IP Right Cessation
-
1974
- 1974-01-01 AR AR255569A patent/AR207764A1/es active
- 1974-08-06 YU YU02178/74A patent/YU217874A/xx unknown
- 1974-08-19 ZA ZA00745317A patent/ZA745317B/xx unknown
- 1974-08-21 IL IL45510A patent/IL45510A/xx unknown
- 1974-08-21 CA CA207,509A patent/CA1037476A/en not_active Expired
- 1974-09-02 FI FI2561/74A patent/FI58638C/fi active
- 1974-09-03 NL NL7411685.A patent/NL155827B/xx not_active IP Right Cessation
- 1974-09-04 DK DK468374AA patent/DK135683B/da unknown
- 1974-09-06 PL PL1974195308A patent/PL99159B1/pl unknown
- 1974-09-06 PL PL1974173909A patent/PL97757B1/pl unknown
- 1974-09-09 IE IE1870/74A patent/IE40523B1/xx unknown
- 1974-09-09 PH PH16253A patent/PH10643A/en unknown
- 1974-09-09 SE SE7411382A patent/SE419443B/sv unknown
- 1974-09-10 FR FR7430568A patent/FR2242984B1/fr not_active Expired
- 1974-09-10 DD DD181015A patent/DD116824A5/xx unknown
- 1974-09-10 JP JP49103536A patent/JPS6042238B2/ja not_active Expired
- 1974-09-10 DD DD190238A patent/DD122785A5/xx unknown
- 1974-09-10 LU LU70878A patent/LU70878A1/xx unknown
- 1974-09-11 ES ES429949A patent/ES429949A1/es not_active Expired
- 1974-09-11 GB GB47894/76A patent/GB1484483A/en not_active Expired
- 1974-09-11 AT AT735174A patent/AT338797B/de not_active IP Right Cessation
- 1974-09-11 SU SU7402058406A patent/SU577987A3/ru active
- 1974-09-11 GB GB39617/74A patent/GB1484481A/en not_active Expired
- 1974-09-11 HU HUHO1718A patent/HU170427B/hu not_active IP Right Cessation
- 1974-09-11 BE BE148396A patent/BE819773A/xx not_active IP Right Cessation
- 1974-09-11 CU CU34115A patent/CU34115A/es unknown
- 1974-09-11 NO NO743271A patent/NO140858C/no unknown
- 1974-09-11 GB GB47893/76A patent/GB1484482A/en not_active Expired
- 1974-09-12 BR BR7614/74A patent/BR7407614D0/pt unknown
- 1974-09-12 DE DE2443682A patent/DE2443682C2/de not_active Expired
-
1975
- 1975-04-25 ES ES437007A patent/ES437007A1/es not_active Expired
- 1975-04-25 ES ES437011A patent/ES437011A1/es not_active Expired
- 1975-04-25 ES ES437012A patent/ES437012A1/es not_active Expired
- 1975-04-25 ES ES437008A patent/ES437008A1/es not_active Expired
- 1975-04-25 ES ES437013A patent/ES437013A1/es not_active Expired
- 1975-04-25 ES ES437009A patent/ES437009A1/es not_active Expired
- 1975-06-20 SU SU752145937A patent/SU609465A3/ru active
- 1975-06-20 SU SU7502145932A patent/SU571189A3/ru active
- 1975-06-30 AR AR259408A patent/AR211387Q/es unknown
-
1980
- 1980-11-27 YU YU3016/80A patent/YU37154B/xx unknown
- 1980-11-27 YU YU3015/80A patent/YU37153B/xx unknown
-
1981
- 1981-01-08 HK HK1/81A patent/HK181A/xx unknown
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