DK1334962T3 - Fremgangsmåder til fremstilling af acylphenylalanin - Google Patents
Fremgangsmåder til fremstilling af acylphenylalaninInfo
- Publication number
- DK1334962T3 DK1334962T3 DK01974874T DK01974874T DK1334962T3 DK 1334962 T3 DK1334962 T3 DK 1334962T3 DK 01974874 T DK01974874 T DK 01974874T DK 01974874 T DK01974874 T DK 01974874T DK 1334962 T3 DK1334962 T3 DK 1334962T3
- Authority
- DK
- Denmark
- Prior art keywords
- acylphenylalanine
- preparing
- methods
- solvent
- phenylalanine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000317603 | 2000-10-18 | ||
PCT/JP2001/009068 WO2002032853A1 (fr) | 2000-10-18 | 2001-10-16 | Procede de preparation d'acylphenylalanines |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1334962T3 true DK1334962T3 (da) | 2007-12-10 |
Family
ID=18796361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01974874T DK1334962T3 (da) | 2000-10-18 | 2001-10-16 | Fremgangsmåder til fremstilling af acylphenylalanin |
Country Status (18)
Country | Link |
---|---|
US (2) | US7030268B2 (de) |
EP (1) | EP1334962B1 (de) |
JP (1) | JP4158192B2 (de) |
KR (1) | KR100783306B1 (de) |
CN (1) | CN1273442C (de) |
AT (1) | ATE373635T1 (de) |
AU (1) | AU2001294264A1 (de) |
BR (1) | BR0114728B1 (de) |
CA (1) | CA2425533C (de) |
CY (1) | CY1107502T1 (de) |
DE (1) | DE60130575T2 (de) |
DK (1) | DK1334962T3 (de) |
ES (1) | ES2290173T3 (de) |
MX (1) | MXPA03003483A (de) |
PT (1) | PT1334962E (de) |
RU (1) | RU2287520C2 (de) |
TW (1) | TW575541B (de) |
WO (1) | WO2002032853A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK14922002A3 (sk) * | 2000-03-17 | 2003-04-01 | Ajinomoto Co., Inc. | Farmaceutický prostriedok na prevenciu, zlepšenie a/alebo liečenie diabetickej komplikácie a použitie postprandiálnej látky na zníženie hladiny krvného cukru |
AU2001294264A1 (en) * | 2000-10-18 | 2002-04-29 | Ajinomoto Co., Inc. | Process for the preparation of acylphenylalanines |
DK1334963T3 (da) * | 2000-10-18 | 2007-09-24 | Ajinomoto Kk | Fremgangsmåde til fremstilling af nateglinidkrystal |
PT1334721E (pt) * | 2000-10-24 | 2009-06-01 | Ajinomoto Kk | Preparações de fármacos hidrofílicos contendo nateglinida |
DK1334964T3 (da) * | 2000-10-24 | 2007-09-24 | Ajinomoto Kk | Fremgangsmåde til fremstilling af nateglinidkrystaller med B form |
CA2426263C (en) * | 2000-10-24 | 2010-05-25 | Ajinomoto Co., Inc. | Nateglinide-containing preparation |
DE60310734T2 (de) * | 2003-11-26 | 2007-10-11 | A.M.S.A. Anonima Matèrie Sintètiche e Affini S.p.A. | Verfahren zur Herstellung von Nateglinid in der B-Form |
US7425648B2 (en) | 2005-01-03 | 2008-09-16 | A.M.S.A. Anonima Materie Sintetiche E. Affini S.P.A. | Process for the preparation of nateglinide, preferably in B-form |
KR20070102694A (ko) * | 2005-01-31 | 2007-10-19 | 아지노모토 가부시키가이샤 | 혈당 강하제를 함유하는, 내당능 이상, 경계형 당뇨병,인슐린 저항성 및 고인슐린혈증 개선 또는 치료용 의약조성물 |
KR101399916B1 (ko) * | 2006-03-31 | 2014-05-28 | 아지노모토 가부시키가이샤 | 카복실산 클로라이드 화합물의 제조방법 |
WO2011157986A1 (en) * | 2010-06-14 | 2011-12-22 | Cipla Limited | A process for the preparation of nateglinide |
CN115340857B (zh) * | 2022-08-24 | 2024-03-26 | 宁波锋成先进能源材料研究院有限公司 | 一种原位自乳化纳米驱油剂及其制备方法和应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3382112D1 (de) * | 1982-04-30 | 1991-02-21 | Ajinomoto Kk | Pharmazeutische zusammensetzung. |
JPS59190926A (ja) | 1983-04-14 | 1984-10-29 | Ajinomoto Co Inc | 吸収性付与剤 |
JPS58189121A (ja) | 1982-04-30 | 1983-11-04 | Ajinomoto Co Inc | インシユリン投与賦活剤 |
JPS6354321A (ja) * | 1985-03-27 | 1988-03-08 | Ajinomoto Co Inc | 血糖降下剤 |
DE10199058I2 (de) * | 1991-07-30 | 2006-04-27 | Alcm Co | Kristalle von N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanin und Verfahren zu ihrer Herstellung |
JP2969397B2 (ja) * | 1991-09-10 | 1999-11-02 | 花王株式会社 | N−長鎖アシル−β−アラニンの製造方法 |
JP3025725B2 (ja) * | 1992-11-24 | 2000-03-27 | 花王株式会社 | N−長鎖アシルアミノ酸の分離法及び精製法 |
JPH06256276A (ja) * | 1993-03-02 | 1994-09-13 | Kao Corp | N−長鎖アシルアミノ酸塩の製造方法 |
JPH0717899A (ja) * | 1993-07-01 | 1995-01-20 | Ajinomoto Co Inc | カルボン酸クロリドの製造法 |
PT965339E (pt) * | 1996-11-15 | 2006-06-30 | Ajinomoto Kk | Composicao de nateglinida em comprimidos |
US6844006B1 (en) * | 1999-07-09 | 2005-01-18 | Pennfield Oil Company | Process and apparatus for the preparation of chlortetracycline-containing animal feed compositions |
ATE310507T1 (de) * | 1999-12-28 | 2005-12-15 | Ajinomoto Kk | Orale zusammensetzungen für diabetes |
SK14922002A3 (sk) * | 2000-03-17 | 2003-04-01 | Ajinomoto Co., Inc. | Farmaceutický prostriedok na prevenciu, zlepšenie a/alebo liečenie diabetickej komplikácie a použitie postprandiálnej látky na zníženie hladiny krvného cukru |
DK1334963T3 (da) * | 2000-10-18 | 2007-09-24 | Ajinomoto Kk | Fremgangsmåde til fremstilling af nateglinidkrystal |
AU2001294264A1 (en) * | 2000-10-18 | 2002-04-29 | Ajinomoto Co., Inc. | Process for the preparation of acylphenylalanines |
CA2426263C (en) * | 2000-10-24 | 2010-05-25 | Ajinomoto Co., Inc. | Nateglinide-containing preparation |
DK1334964T3 (da) * | 2000-10-24 | 2007-09-24 | Ajinomoto Kk | Fremgangsmåde til fremstilling af nateglinidkrystaller med B form |
-
2001
- 2001-10-16 AU AU2001294264A patent/AU2001294264A1/en not_active Abandoned
- 2001-10-16 KR KR1020037005384A patent/KR100783306B1/ko not_active IP Right Cessation
- 2001-10-16 CN CNB018206727A patent/CN1273442C/zh not_active Expired - Fee Related
- 2001-10-16 JP JP2002536037A patent/JP4158192B2/ja not_active Expired - Lifetime
- 2001-10-16 EP EP01974874A patent/EP1334962B1/de not_active Expired - Lifetime
- 2001-10-16 WO PCT/JP2001/009068 patent/WO2002032853A1/ja active IP Right Grant
- 2001-10-16 CA CA2425533A patent/CA2425533C/en not_active Expired - Fee Related
- 2001-10-16 ES ES01974874T patent/ES2290173T3/es not_active Expired - Lifetime
- 2001-10-16 DE DE60130575T patent/DE60130575T2/de not_active Expired - Lifetime
- 2001-10-16 RU RU2003111012/04A patent/RU2287520C2/ru not_active IP Right Cessation
- 2001-10-16 BR BRPI0114728-5A patent/BR0114728B1/pt not_active IP Right Cessation
- 2001-10-16 MX MXPA03003483A patent/MXPA03003483A/es active IP Right Grant
- 2001-10-16 AT AT01974874T patent/ATE373635T1/de active
- 2001-10-16 DK DK01974874T patent/DK1334962T3/da active
- 2001-10-16 PT PT01974874T patent/PT1334962E/pt unknown
- 2001-10-17 TW TW090125695A patent/TW575541B/zh not_active IP Right Cessation
-
2003
- 2003-04-18 US US10/418,102 patent/US7030268B2/en not_active Expired - Fee Related
-
2005
- 2005-12-28 US US11/319,177 patent/US7659428B2/en not_active Expired - Fee Related
-
2007
- 2007-09-26 CY CY20071101237T patent/CY1107502T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU2001294264A1 (en) | 2002-04-29 |
US7030268B2 (en) | 2006-04-18 |
CA2425533C (en) | 2010-04-20 |
DE60130575D1 (de) | 2007-10-31 |
WO2002032853A1 (fr) | 2002-04-25 |
US20040024219A1 (en) | 2004-02-05 |
KR100783306B1 (ko) | 2007-12-10 |
BR0114728A (pt) | 2003-10-14 |
CA2425533A1 (en) | 2003-04-10 |
US7659428B2 (en) | 2010-02-09 |
PT1334962E (pt) | 2007-10-09 |
EP1334962A1 (de) | 2003-08-13 |
CN1481355A (zh) | 2004-03-10 |
CN1273442C (zh) | 2006-09-06 |
KR20030059202A (ko) | 2003-07-07 |
JP4158192B2 (ja) | 2008-10-01 |
TW575541B (en) | 2004-02-11 |
CY1107502T1 (el) | 2013-03-13 |
ATE373635T1 (de) | 2007-10-15 |
US20060155143A1 (en) | 2006-07-13 |
MXPA03003483A (es) | 2003-07-14 |
EP1334962A4 (de) | 2005-08-24 |
JPWO2002032853A1 (ja) | 2004-02-26 |
BR0114728B1 (pt) | 2014-01-14 |
DE60130575T2 (de) | 2008-04-30 |
ES2290173T3 (es) | 2008-02-16 |
RU2287520C2 (ru) | 2006-11-20 |
EP1334962B1 (de) | 2007-09-19 |
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