DK1334962T3 - Fremgangsmåder til fremstilling af acylphenylalanin - Google Patents

Fremgangsmåder til fremstilling af acylphenylalanin

Info

Publication number
DK1334962T3
DK1334962T3 DK01974874T DK01974874T DK1334962T3 DK 1334962 T3 DK1334962 T3 DK 1334962T3 DK 01974874 T DK01974874 T DK 01974874T DK 01974874 T DK01974874 T DK 01974874T DK 1334962 T3 DK1334962 T3 DK 1334962T3
Authority
DK
Denmark
Prior art keywords
acylphenylalanine
preparing
methods
solvent
phenylalanine
Prior art date
Application number
DK01974874T
Other languages
Danish (da)
English (en)
Inventor
Michito Sumikawa
Takao Ohgane
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of DK1334962T3 publication Critical patent/DK1334962T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK01974874T 2000-10-18 2001-10-16 Fremgangsmåder til fremstilling af acylphenylalanin DK1334962T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000317603 2000-10-18
PCT/JP2001/009068 WO2002032853A1 (fr) 2000-10-18 2001-10-16 Procede de preparation d'acylphenylalanines

Publications (1)

Publication Number Publication Date
DK1334962T3 true DK1334962T3 (da) 2007-12-10

Family

ID=18796361

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01974874T DK1334962T3 (da) 2000-10-18 2001-10-16 Fremgangsmåder til fremstilling af acylphenylalanin

Country Status (18)

Country Link
US (2) US7030268B2 (de)
EP (1) EP1334962B1 (de)
JP (1) JP4158192B2 (de)
KR (1) KR100783306B1 (de)
CN (1) CN1273442C (de)
AT (1) ATE373635T1 (de)
AU (1) AU2001294264A1 (de)
BR (1) BR0114728B1 (de)
CA (1) CA2425533C (de)
CY (1) CY1107502T1 (de)
DE (1) DE60130575T2 (de)
DK (1) DK1334962T3 (de)
ES (1) ES2290173T3 (de)
MX (1) MXPA03003483A (de)
PT (1) PT1334962E (de)
RU (1) RU2287520C2 (de)
TW (1) TW575541B (de)
WO (1) WO2002032853A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK14922002A3 (sk) * 2000-03-17 2003-04-01 Ajinomoto Co., Inc. Farmaceutický prostriedok na prevenciu, zlepšenie a/alebo liečenie diabetickej komplikácie a použitie postprandiálnej látky na zníženie hladiny krvného cukru
AU2001294264A1 (en) * 2000-10-18 2002-04-29 Ajinomoto Co., Inc. Process for the preparation of acylphenylalanines
DK1334963T3 (da) * 2000-10-18 2007-09-24 Ajinomoto Kk Fremgangsmåde til fremstilling af nateglinidkrystal
PT1334721E (pt) * 2000-10-24 2009-06-01 Ajinomoto Kk Preparações de fármacos hidrofílicos contendo nateglinida
DK1334964T3 (da) * 2000-10-24 2007-09-24 Ajinomoto Kk Fremgangsmåde til fremstilling af nateglinidkrystaller med B form
CA2426263C (en) * 2000-10-24 2010-05-25 Ajinomoto Co., Inc. Nateglinide-containing preparation
DE60310734T2 (de) * 2003-11-26 2007-10-11 A.M.S.A. Anonima Matèrie Sintètiche e Affini S.p.A. Verfahren zur Herstellung von Nateglinid in der B-Form
US7425648B2 (en) 2005-01-03 2008-09-16 A.M.S.A. Anonima Materie Sintetiche E. Affini S.P.A. Process for the preparation of nateglinide, preferably in B-form
KR20070102694A (ko) * 2005-01-31 2007-10-19 아지노모토 가부시키가이샤 혈당 강하제를 함유하는, 내당능 이상, 경계형 당뇨병,인슐린 저항성 및 고인슐린혈증 개선 또는 치료용 의약조성물
KR101399916B1 (ko) * 2006-03-31 2014-05-28 아지노모토 가부시키가이샤 카복실산 클로라이드 화합물의 제조방법
WO2011157986A1 (en) * 2010-06-14 2011-12-22 Cipla Limited A process for the preparation of nateglinide
CN115340857B (zh) * 2022-08-24 2024-03-26 宁波锋成先进能源材料研究院有限公司 一种原位自乳化纳米驱油剂及其制备方法和应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3382112D1 (de) * 1982-04-30 1991-02-21 Ajinomoto Kk Pharmazeutische zusammensetzung.
JPS59190926A (ja) 1983-04-14 1984-10-29 Ajinomoto Co Inc 吸収性付与剤
JPS58189121A (ja) 1982-04-30 1983-11-04 Ajinomoto Co Inc インシユリン投与賦活剤
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
DE10199058I2 (de) * 1991-07-30 2006-04-27 Alcm Co Kristalle von N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanin und Verfahren zu ihrer Herstellung
JP2969397B2 (ja) * 1991-09-10 1999-11-02 花王株式会社 N−長鎖アシル−β−アラニンの製造方法
JP3025725B2 (ja) * 1992-11-24 2000-03-27 花王株式会社 N−長鎖アシルアミノ酸の分離法及び精製法
JPH06256276A (ja) * 1993-03-02 1994-09-13 Kao Corp N−長鎖アシルアミノ酸塩の製造方法
JPH0717899A (ja) * 1993-07-01 1995-01-20 Ajinomoto Co Inc カルボン酸クロリドの製造法
PT965339E (pt) * 1996-11-15 2006-06-30 Ajinomoto Kk Composicao de nateglinida em comprimidos
US6844006B1 (en) * 1999-07-09 2005-01-18 Pennfield Oil Company Process and apparatus for the preparation of chlortetracycline-containing animal feed compositions
ATE310507T1 (de) * 1999-12-28 2005-12-15 Ajinomoto Kk Orale zusammensetzungen für diabetes
SK14922002A3 (sk) * 2000-03-17 2003-04-01 Ajinomoto Co., Inc. Farmaceutický prostriedok na prevenciu, zlepšenie a/alebo liečenie diabetickej komplikácie a použitie postprandiálnej látky na zníženie hladiny krvného cukru
DK1334963T3 (da) * 2000-10-18 2007-09-24 Ajinomoto Kk Fremgangsmåde til fremstilling af nateglinidkrystal
AU2001294264A1 (en) * 2000-10-18 2002-04-29 Ajinomoto Co., Inc. Process for the preparation of acylphenylalanines
CA2426263C (en) * 2000-10-24 2010-05-25 Ajinomoto Co., Inc. Nateglinide-containing preparation
DK1334964T3 (da) * 2000-10-24 2007-09-24 Ajinomoto Kk Fremgangsmåde til fremstilling af nateglinidkrystaller med B form

Also Published As

Publication number Publication date
AU2001294264A1 (en) 2002-04-29
US7030268B2 (en) 2006-04-18
CA2425533C (en) 2010-04-20
DE60130575D1 (de) 2007-10-31
WO2002032853A1 (fr) 2002-04-25
US20040024219A1 (en) 2004-02-05
KR100783306B1 (ko) 2007-12-10
BR0114728A (pt) 2003-10-14
CA2425533A1 (en) 2003-04-10
US7659428B2 (en) 2010-02-09
PT1334962E (pt) 2007-10-09
EP1334962A1 (de) 2003-08-13
CN1481355A (zh) 2004-03-10
CN1273442C (zh) 2006-09-06
KR20030059202A (ko) 2003-07-07
JP4158192B2 (ja) 2008-10-01
TW575541B (en) 2004-02-11
CY1107502T1 (el) 2013-03-13
ATE373635T1 (de) 2007-10-15
US20060155143A1 (en) 2006-07-13
MXPA03003483A (es) 2003-07-14
EP1334962A4 (de) 2005-08-24
JPWO2002032853A1 (ja) 2004-02-26
BR0114728B1 (pt) 2014-01-14
DE60130575T2 (de) 2008-04-30
ES2290173T3 (es) 2008-02-16
RU2287520C2 (ru) 2006-11-20
EP1334962B1 (de) 2007-09-19

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