DK1273575T3 - Diazepan derivater eller salte deraf - Google Patents
Diazepan derivater eller salte derafInfo
- Publication number
- DK1273575T3 DK1273575T3 DK01917634T DK01917634T DK1273575T3 DK 1273575 T3 DK1273575 T3 DK 1273575T3 DK 01917634 T DK01917634 T DK 01917634T DK 01917634 T DK01917634 T DK 01917634T DK 1273575 T3 DK1273575 T3 DK 1273575T3
- Authority
- DK
- Denmark
- Prior art keywords
- salts
- diazepan derivatives
- diazepan
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000096858 | 2000-03-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1273575T3 true DK1273575T3 (da) | 2004-09-13 |
Family
ID=18611560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01917634T DK1273575T3 (da) | 2000-03-31 | 2001-03-29 | Diazepan derivater eller salte deraf |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US6642224B1 (zh) |
| EP (2) | EP1415990B1 (zh) |
| JP (1) | JP3788349B2 (zh) |
| KR (1) | KR100739359B1 (zh) |
| CN (1) | CN1226292C (zh) |
| AR (1) | AR027985A1 (zh) |
| AT (2) | ATE340166T1 (zh) |
| AU (2) | AU776053B2 (zh) |
| BR (1) | BR0101264A (zh) |
| CA (1) | CA2395846C (zh) |
| DE (2) | DE60103390T2 (zh) |
| DK (1) | DK1273575T3 (zh) |
| ES (2) | ES2217129T3 (zh) |
| HU (1) | HUP0101333A3 (zh) |
| MX (1) | MXPA01003279A (zh) |
| PL (1) | PL207651B1 (zh) |
| PT (1) | PT1273575E (zh) |
| RU (1) | RU2257381C2 (zh) |
| TR (1) | TR200401955T4 (zh) |
| TW (1) | TW575569B (zh) |
| WO (1) | WO2001074791A1 (zh) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001064642A2 (en) * | 2000-02-29 | 2001-09-07 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| AU776053B2 (en) | 2000-03-31 | 2004-08-26 | Astellas Pharma Inc. | Diazepan derivatives or salts thereof |
| WO2002010154A2 (en) | 2000-07-27 | 2002-02-07 | Eli Lilly And Company | Substituted heterocyclic amides |
| CA2424522C (en) | 2000-11-22 | 2009-12-29 | Yamanouchi Pharmaceutical Co., Ltd. | Substituted benzene derivatives or salts thereof |
| AU2001297648A1 (en) * | 2000-11-28 | 2002-08-28 | Eli Lilly And Company | Substituted carboxamides as inhibitors of factor xa |
| SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
| WO2003050088A1 (en) * | 2001-12-07 | 2003-06-19 | Eli Lilly And Company | Substituted heterocyclic carboxamides with antithrombotic activity |
| TWI319387B (en) * | 2002-04-05 | 2010-01-11 | Astrazeneca Ab | Benzamide derivatives |
| JP5015593B2 (ja) * | 2003-06-18 | 2012-08-29 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血栓症の治療のための凝固因子ＸａおよびＶＩＩａの阻害剤としての１−［（４−エチニルフェニル）］−２−［（フェニル）］−ピロリジン−１，２−ジカルボキサミド誘導体 |
| EP1670783A2 (en) | 2003-09-30 | 2006-06-21 | Eli Lilly And Company | Antithrombotic aromatic ethers |
| EP1817287B1 (en) | 2004-11-24 | 2010-02-10 | Eli Lilly And Company | Aromatic ether derivatives useful as thrombin inhibitors |
| WO2006057868A1 (en) | 2004-11-29 | 2006-06-01 | Eli Lilly And Company | Antithrombotic diamides |
| JP4900238B2 (ja) | 2005-02-02 | 2012-03-21 | 味の素株式会社 | 新規ベンズアミジン化合物 |
| GB0521244D0 (en) | 2005-10-19 | 2005-11-30 | Astrazeneca Ab | Benzamide compounds |
| TW200734304A (en) * | 2005-11-08 | 2007-09-16 | Astellas Pharma Inc | Benzene derivative or salt thereof |
| EP2404906B1 (en) | 2006-11-02 | 2015-07-15 | Millennium Pharmaceuticals, Inc. | Methods of synthesizing pharmaceutical salts of a factor XA inhibitor |
| JP2010120852A (ja) * | 2007-03-09 | 2010-06-03 | Daiichi Sankyo Co Ltd | 新規なジアミド誘導体 |
| KR20110036833A (ko) * | 2008-07-11 | 2011-04-11 | 아지노모토 가부시키가이샤 | 아미딘 유도체 |
| TW201021832A (en) * | 2008-09-30 | 2010-06-16 | Astellas Pharma Inc | Pharmaceutical composition for oral administration |
| JP5823514B2 (ja) | 2010-07-07 | 2015-11-25 | アーデリクス，インコーポレーテッド | リン酸輸送を阻害する化合物及び方法 |
| EP2590510B1 (en) | 2010-07-07 | 2016-09-28 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| EP2590965B1 (en) | 2010-07-07 | 2016-04-20 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| EP2591354B1 (en) * | 2010-07-07 | 2016-09-07 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| WO2012006473A1 (en) * | 2010-07-07 | 2012-01-12 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| EP2635559A2 (en) * | 2010-11-01 | 2013-09-11 | Neurotune AG | Neurotrypsin inhibitors |
| JPWO2013161871A1 (ja) * | 2012-04-25 | 2015-12-24 | 興和株式会社 | Ｔｌｒ阻害作用を有するチオフェン誘導体 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5417200A (en) * | 1994-01-25 | 1995-05-23 | Wasielewski; John J. | Lantern cooker |
| NZ296210A (en) | 1994-12-02 | 1998-05-27 | Yamanouchi Pharma Co Ltd | Amidinonaphthyl derivatives to inhibit activated blood coagulation factor x |
| DE69830504T2 (de) | 1997-06-26 | 2006-03-16 | Eli Lilly And Co., Indianapolis | Antithrombotische mitteln |
| WO1999000121A1 (en) | 1997-06-26 | 1999-01-07 | Eli Lilly And Company | Antithrombotic agents |
| US6417200B1 (en) | 1997-06-26 | 2002-07-09 | Eli Lilly And Company | Antithrombotic agents |
| US6313151B1 (en) | 1997-06-26 | 2001-11-06 | Eli Lilly And Company | Antithrombotic agents |
| US6140351A (en) | 1997-12-19 | 2000-10-31 | Berlex Laboratories, Inc. | Ortho-anthranilamide derivatives as anti-coagulants |
| NZ503809A (en) | 1997-12-19 | 2002-04-26 | Schering Ag | Ortho-anthranilamide derivatives as anti-coagulants |
| AU2074699A (en) | 1998-01-26 | 1999-08-09 | Yamanouchi Pharmaceutical Co., Ltd. | Novel benzene-fused heterocyclic derivatives or salts thereof |
| ES2263294T3 (es) | 1998-12-23 | 2006-12-01 | Eli Lilly And Company | Amidas antitromboticas. |
| ATE240316T1 (de) | 1998-12-23 | 2003-05-15 | Lilly Co Eli | Heteroaromatische amide als inhibitoren von faktor xa |
| US6635657B1 (en) | 1998-12-23 | 2003-10-21 | Eli Lilly And Company | Aromatic amides |
| JP4390024B2 (ja) * | 1999-04-23 | 2009-12-24 | アステラス製薬株式会社 | 新規なジアゼパン誘導体又はその塩 |
| IL148698A0 (en) | 1999-09-17 | 2002-09-12 | Cor Therapeutics Inc | INHIBITORS OF FACTOR Xa |
| CZ2002961A3 (cs) | 1999-09-17 | 2002-08-14 | Millennium Pharmaceuticals, Inc. | Benzamidy a příbuzné sloučeniny pro inhibici faktoru Xa |
| US6632815B2 (en) | 1999-09-17 | 2003-10-14 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| WO2001064642A2 (en) | 2000-02-29 | 2001-09-07 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| AU776053B2 (en) | 2000-03-31 | 2004-08-26 | Astellas Pharma Inc. | Diazepan derivatives or salts thereof |
| WO2002010154A2 (en) * | 2000-07-27 | 2002-02-07 | Eli Lilly And Company | Substituted heterocyclic amides |
| AU2001297648A1 (en) * | 2000-11-28 | 2002-08-28 | Eli Lilly And Company | Substituted carboxamides as inhibitors of factor xa |
-
2001
- 2001-03-22 AU AU29827/01A patent/AU776053B2/en not_active Ceased
- 2001-03-28 PL PL346731A patent/PL207651B1/pl not_active IP Right Cessation
- 2001-03-29 DK DK01917634T patent/DK1273575T3/da active
- 2001-03-29 CA CA002395846A patent/CA2395846C/en not_active Expired - Fee Related
- 2001-03-29 US US10/148,544 patent/US6642224B1/en not_active Expired - Fee Related
- 2001-03-29 EP EP03029061A patent/EP1415990B1/en not_active Expired - Lifetime
- 2001-03-29 EP EP01917634A patent/EP1273575B1/en not_active Expired - Lifetime
- 2001-03-29 RU RU2001108494/04A patent/RU2257381C2/ru not_active IP Right Cessation
- 2001-03-29 AR ARP010101497A patent/AR027985A1/es active IP Right Grant
- 2001-03-29 AT AT03029061T patent/ATE340166T1/de not_active IP Right Cessation
- 2001-03-29 DE DE60103390T patent/DE60103390T2/de not_active Expired - Lifetime
- 2001-03-29 DE DE60123294T patent/DE60123294T2/de not_active Expired - Lifetime
- 2001-03-29 WO PCT/JP2001/002673 patent/WO2001074791A1/ja active IP Right Grant
- 2001-03-29 AT AT01917634T patent/ATE267178T1/de active
- 2001-03-29 MX MXPA01003279A patent/MXPA01003279A/es active IP Right Grant
- 2001-03-29 AU AU2001244634A patent/AU2001244634A1/en not_active Abandoned
- 2001-03-29 PT PT01917634T patent/PT1273575E/pt unknown
- 2001-03-29 TR TR2004/01955T patent/TR200401955T4/xx unknown
- 2001-03-29 ES ES01917634T patent/ES2217129T3/es not_active Expired - Lifetime
- 2001-03-29 ES ES03029061T patent/ES2271464T3/es not_active Expired - Lifetime
- 2001-03-29 JP JP2001572486A patent/JP3788349B2/ja not_active Expired - Fee Related
- 2001-03-30 HU HU0101333A patent/HUP0101333A3/hu unknown
- 2001-03-30 KR KR1020010016952A patent/KR100739359B1/ko not_active IP Right Cessation
- 2001-03-30 CN CNB011121904A patent/CN1226292C/zh not_active Expired - Fee Related
- 2001-03-30 TW TW90107761A patent/TW575569B/zh not_active IP Right Cessation
- 2001-03-30 BR BR0101264-9A patent/BR0101264A/pt not_active IP Right Cessation
-
2003
- 2003-09-08 US US10/656,129 patent/US7307074B2/en not_active Ceased
-
2008
- 2008-09-03 US US12/203,640 patent/USRE43481E1/en not_active Expired - Fee Related
Also Published As
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