DK1230347T3 - Fremgangsmåde til fremstilling af oprenset HCV-RNA ved exosomseparering - Google Patents

Fremgangsmåde til fremstilling af oprenset HCV-RNA ved exosomseparering

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Publication number
DK1230347T3
DK1230347T3 DK00979837T DK00979837T DK1230347T3 DK 1230347 T3 DK1230347 T3 DK 1230347T3 DK 00979837 T DK00979837 T DK 00979837T DK 00979837 T DK00979837 T DK 00979837T DK 1230347 T3 DK1230347 T3 DK 1230347T3
Authority
DK
Denmark
Prior art keywords
preparation
hcv rna
purified hcv
exosome separation
separation
Prior art date
Application number
DK00979837T
Other languages
Danish (da)
English (en)
Inventor
Sergio Abrignani
Piero Pileri
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of DK1230347T3 publication Critical patent/DK1230347T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24251Methods of production or purification of viral material

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)
DK00979837T 1999-11-18 2000-11-20 Fremgangsmåde til fremstilling af oprenset HCV-RNA ved exosomseparering DK1230347T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9927320.3A GB9927320D0 (en) 1999-11-18 1999-11-18 Exosome separation
PCT/IB2000/001801 WO2001036601A1 (en) 1999-11-18 2000-11-20 Method for the preparation of purified hcv rna by exosome separation

Publications (1)

Publication Number Publication Date
DK1230347T3 true DK1230347T3 (da) 2007-11-05

Family

ID=10864765

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00979837T DK1230347T3 (da) 1999-11-18 2000-11-20 Fremgangsmåde til fremstilling af oprenset HCV-RNA ved exosomseparering

Country Status (13)

Country Link
US (2) US7198923B1 (ja)
EP (1) EP1230347B1 (ja)
JP (1) JP4675017B2 (ja)
AT (1) ATE373084T1 (ja)
AU (1) AU1721801A (ja)
CA (1) CA2392075C (ja)
CY (1) CY1107521T1 (ja)
DE (1) DE60036403T2 (ja)
DK (1) DK1230347T3 (ja)
ES (1) ES2292489T3 (ja)
GB (1) GB9927320D0 (ja)
PT (1) PT1230347E (ja)
WO (1) WO2001036601A1 (ja)

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Also Published As

Publication number Publication date
JP2003514523A (ja) 2003-04-22
EP1230347B1 (en) 2007-09-12
US7198923B1 (en) 2007-04-03
US20070254351A1 (en) 2007-11-01
EP1230347A1 (en) 2002-08-14
CA2392075C (en) 2011-01-04
CY1107521T1 (el) 2013-03-13
DE60036403T2 (de) 2008-06-12
DE60036403D1 (de) 2007-10-25
US7807438B2 (en) 2010-10-05
ES2292489T3 (es) 2008-03-16
ATE373084T1 (de) 2007-09-15
GB9927320D0 (en) 2000-01-12
PT1230347E (pt) 2007-12-20
CA2392075A1 (en) 2001-05-25
AU1721801A (en) 2001-05-30
WO2001036601A1 (en) 2001-05-25
JP4675017B2 (ja) 2011-04-20

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