DK1178982T3 - Heterocykliske, substituerede aminoazacykliske forbindelser, der er nyttige som midler til centralnervesystemet - Google Patents
Heterocykliske, substituerede aminoazacykliske forbindelser, der er nyttige som midler til centralnervesystemetInfo
- Publication number
- DK1178982T3 DK1178982T3 DK00932445T DK00932445T DK1178982T3 DK 1178982 T3 DK1178982 T3 DK 1178982T3 DK 00932445 T DK00932445 T DK 00932445T DK 00932445 T DK00932445 T DK 00932445T DK 1178982 T3 DK1178982 T3 DK 1178982T3
- Authority
- DK
- Denmark
- Prior art keywords
- agents
- nervous system
- central nervous
- heterocyclic substituted
- compounds useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31670799A | 1999-05-21 | 1999-05-21 | |
US09/559,881 US6833370B1 (en) | 1999-05-21 | 2000-04-26 | Heterocycle substituted aminoazacycles useful as central nervous system agents |
PCT/US2000/013339 WO2000071534A1 (en) | 1999-05-21 | 2000-05-15 | Heterocyclic substituted aminoazacycles useful as central nervous system agents |
EP00932445A EP1178982B1 (en) | 1999-05-21 | 2000-05-15 | Heterocyclic substituted aminoazacycles useful as central nervous system agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1178982T3 true DK1178982T3 (da) | 2004-11-08 |
Family
ID=26980553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00932445T DK1178982T3 (da) | 1999-05-21 | 2000-05-15 | Heterocykliske, substituerede aminoazacykliske forbindelser, der er nyttige som midler til centralnervesystemet |
Country Status (24)
Country | Link |
---|---|
EP (2) | EP1428824A1 (pt) |
JP (1) | JP2003500402A (pt) |
KR (2) | KR100714122B1 (pt) |
CN (2) | CN1636990A (pt) |
AT (1) | ATE270288T1 (pt) |
AU (1) | AU781241B2 (pt) |
BG (1) | BG106192A (pt) |
BR (1) | BR0007229A (pt) |
CA (1) | CA2373793A1 (pt) |
CZ (1) | CZ20014127A3 (pt) |
DE (1) | DE60011895T2 (pt) |
DK (1) | DK1178982T3 (pt) |
ES (1) | ES2226844T3 (pt) |
HK (1) | HK1045305B (pt) |
HU (1) | HU225894B1 (pt) |
IL (2) | IL146476A0 (pt) |
MX (1) | MXPA01011897A (pt) |
NO (1) | NO20015669L (pt) |
NZ (1) | NZ515207A (pt) |
PL (1) | PL200427B1 (pt) |
PT (1) | PT1178982E (pt) |
SI (1) | SI1178982T1 (pt) |
SK (1) | SK16812001A3 (pt) |
WO (1) | WO2000071534A1 (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6376472B1 (en) * | 1996-07-08 | 2002-04-23 | Aventis Pharmaceuticals, Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
US6809105B2 (en) | 2000-04-27 | 2004-10-26 | Abbott Laboratories | Diazabicyclic central nervous system active agents |
MY145722A (en) * | 2000-04-27 | 2012-03-30 | Abbott Lab | Diazabicyclic central nervous system active agents |
HUP0200849A2 (hu) * | 2002-03-06 | 2004-08-30 | Sanofi-Synthelabo | N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra |
US20040242641A1 (en) * | 2003-05-27 | 2004-12-02 | Buckley Michael J. | (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane is an effective analgesic agent |
US7399765B2 (en) | 2003-09-19 | 2008-07-15 | Abbott Laboratories | Substituted diazabicycloalkane derivatives |
US8580842B2 (en) | 2003-09-30 | 2013-11-12 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
US20080167286A1 (en) | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
US8486979B2 (en) | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
UY30846A1 (es) | 2006-12-30 | 2008-07-31 | Abbott Gmbh & Amp | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos |
MX2010006206A (es) | 2007-12-07 | 2011-03-04 | Abbott Gmbh & Co Kg | Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina. |
US8703774B2 (en) | 2007-12-07 | 2014-04-22 | AbbVie Deutschland GmbH & Co. KG | Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases |
US8703775B2 (en) | 2007-12-07 | 2014-04-22 | AbbVie Deutschland GmbH & Co. KG | Amidomethyl-substituted oxindole derivatives and the use thereof for the treatment of vasopressin-dependent illnesses |
JP5645217B2 (ja) | 2007-12-07 | 2014-12-24 | アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | 5,6−二置換オキシンドール誘導体およびバソプレッシン依存性疾患を治療するためのこれらの使用 |
US8383657B2 (en) | 2007-12-21 | 2013-02-26 | Abbott Laboratories | Thiazolylidine urea and amide derivatives and methods of use thereof |
US20100331546A1 (en) * | 2008-02-27 | 2010-12-30 | Sumitomo Chemical Company, Limited | Method for optical resolution of alkyl piperidin-3-yl carbamate and intermediate therefor |
JP2009256298A (ja) * | 2008-03-26 | 2009-11-05 | Sumitomo Chemical Co Ltd | ピペリジン−3−イルカーバメート化合物の光学分割方法およびその中間体 |
US9463190B2 (en) | 2008-03-31 | 2016-10-11 | University Of South Florida | Methods of treating disease-induced ataxia and non-ataxic imbalance |
US8383658B2 (en) | 2008-06-04 | 2013-02-26 | Abbott Laboratories | Isoxazole based neuronal nicotinic receptor ligands and methods of use |
TW201022233A (en) * | 2008-11-04 | 2010-06-16 | Organon Nv | (Pyrrolidin-2-yl)phenyl derivatives |
EP2435080A2 (en) | 2009-05-29 | 2012-04-04 | Abbott Laboratories | Pharmaceutical compositions for the treatment of pain |
US8268853B2 (en) | 2009-06-25 | 2012-09-18 | Abbott Laboratories | 3,9-diazaspiro[5,5]undecane amides and ureas and methods of use thereof |
UY32826A (es) | 2009-08-04 | 2011-02-28 | Takeda Pharmaceutical | Compuestos heterocíclicos |
CN102936220B (zh) * | 2012-11-15 | 2014-07-02 | 河北桑迪亚医药技术有限责任公司 | 一种氨基吡啶boc保护的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4302456A (en) * | 1977-04-13 | 1981-11-24 | The Upjohn Company | Process for therapeutic treatment |
FR2459240A1 (fr) * | 1979-06-21 | 1981-01-09 | Cm Ind | Aminopiperidines anorexigenes, procede pour leur preparation, intermediaires dans ledit procede et medicaments qui les contiennent |
US4302455A (en) * | 1980-04-14 | 1981-11-24 | Merck & Co., Inc. | 2-(4-Aminopiperidino)pyrazines |
CA2133855A1 (en) * | 1993-10-11 | 1995-04-12 | Marco Baroni | Heteroarylpiperidines, process for their preparation and pharmaceutical compositions in which they are present |
EP0647639A1 (fr) * | 1993-10-11 | 1995-04-12 | Sanofi | Hétéroarylpipéridines, procédé pour leur préparation et compositions pharmaceutiques les contenant |
US5585388A (en) * | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
-
2000
- 2000-05-15 CN CNA2004100855612A patent/CN1636990A/zh active Pending
- 2000-05-15 NZ NZ515207A patent/NZ515207A/en unknown
- 2000-05-15 CN CNB00810672XA patent/CN1192028C/zh not_active Expired - Fee Related
- 2000-05-15 KR KR1020067020961A patent/KR100714122B1/ko not_active IP Right Cessation
- 2000-05-15 PT PT00932445T patent/PT1178982E/pt unknown
- 2000-05-15 SI SI200030480T patent/SI1178982T1/xx unknown
- 2000-05-15 KR KR1020067020954A patent/KR100714121B1/ko not_active IP Right Cessation
- 2000-05-15 DK DK00932445T patent/DK1178982T3/da active
- 2000-05-15 CZ CZ20014127A patent/CZ20014127A3/cs unknown
- 2000-05-15 EP EP04005194A patent/EP1428824A1/en not_active Withdrawn
- 2000-05-15 ES ES00932445T patent/ES2226844T3/es not_active Expired - Lifetime
- 2000-05-15 WO PCT/US2000/013339 patent/WO2000071534A1/en active Application Filing
- 2000-05-15 PL PL352066A patent/PL200427B1/pl unknown
- 2000-05-15 SK SK1681-2001A patent/SK16812001A3/sk unknown
- 2000-05-15 IL IL14647600A patent/IL146476A0/xx unknown
- 2000-05-15 EP EP00932445A patent/EP1178982B1/en not_active Expired - Lifetime
- 2000-05-15 BR BR0007229-0A patent/BR0007229A/pt not_active Application Discontinuation
- 2000-05-15 JP JP2000619791A patent/JP2003500402A/ja not_active Withdrawn
- 2000-05-15 AU AU50166/00A patent/AU781241B2/en not_active Ceased
- 2000-05-15 CA CA002373793A patent/CA2373793A1/en not_active Abandoned
- 2000-05-15 AT AT00932445T patent/ATE270288T1/de not_active IP Right Cessation
- 2000-05-15 HU HU0202034A patent/HU225894B1/hu not_active IP Right Cessation
- 2000-05-15 MX MXPA01011897A patent/MXPA01011897A/es active IP Right Grant
- 2000-05-15 DE DE60011895T patent/DE60011895T2/de not_active Expired - Lifetime
-
2001
- 2001-11-20 NO NO20015669A patent/NO20015669L/no not_active Application Discontinuation
- 2001-12-07 BG BG106192A patent/BG106192A/bg unknown
-
2002
- 2002-07-17 HK HK02105306.6A patent/HK1045305B/zh not_active IP Right Cessation
-
2008
- 2008-04-10 IL IL190780A patent/IL190780A0/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1178982T3 (da) | Heterocykliske, substituerede aminoazacykliske forbindelser, der er nyttige som midler til centralnervesystemet | |
ES2166954T3 (es) | Derivados de 1-fenilpirazol y su uso como agentes parasiticidas. | |
NO20063132L (no) | Naftyridinderivater og deres anvendelse som modulatorer av muskarinreceptorer | |
PT778277E (pt) | Derivados heterociclicos substituidos como antagonistas do crf | |
NO953305L (no) | Antranilsyrederivat | |
BR0013041A (pt) | Composto heterociclico e composição farmacêutica para tratar e prevenir doenças mediadas por cgmp-pde, seu uso e método | |
ATE368653T1 (de) | Oxazolylaryloxyessigsäure derivate und ihre verwendung als ppar agonisten | |
NO20042024L (no) | 4-(4-alkoksy-3-hydroksyfenyl)-2-pyrrolidonderivater som PDE4-inhibitorer for behandling av nevrologiske syndromer | |
DK1078923T3 (da) | Fremgangsmåde til fremstilling af benzothiophenderivater | |
ATE370735T1 (de) | Phenylpyridazinderivate und diese enthaltende arzneimittel | |
HUP0002272A2 (hu) | Piperazinszármazékok, eljárás előállításukra, e vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk | |
TW333527B (en) | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | |
DE50011034D1 (de) | N-substituierte 4-aminopteridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
ES2126075T3 (es) | Derivados biciclicos nitrogenados como inhibidores de la propil-endopeptidasa. | |
AU8811401A (en) | Spiro compounds and adhesion molecule inhibitors containing the same as the active ingredient | |
AR003137A1 (es) | Una composicion farmaceutica para tratar la leucemia | |
CO5080802A1 (es) | Nuevos compuestos heterociclicos inhibidores de la fosfodiesteresa iv y su formulacion y uso como productos farmaceuticos | |
DK1165485T3 (da) | Fremgangsmåde til fremstilling af pesticidmellemprodukter | |
ATE160146T1 (de) | Hetero-tricyclisch-substituierte phenyl- cyclohexan-carbonsäurederivate | |
EP1211253A4 (en) | DIHYDROBENZOFURAN TRICYCLIC DERIVATIVES, THEIR PREPARATION METHOD AND AGENTS | |
BR0207966A (pt) | Composição farmacêutica contendo derivados 1,3-tiazina | |
DK1072601T3 (da) | 4-Arylpiperidinderivater til behandling af pruritus | |
DK0413278T3 (da) | Anvendelse af xanthinderivater mod mavesår | |
ATE258934T1 (de) | Azaindol derivate und ihre verwendung als antithrombotische wirkstoffe | |
DE69018741T2 (de) | Konjugierte gamma-Hydroxybutenolid-Derivate und sie als aktiver Wirkstoff enthaltende Mittel gegen Magengeschwüre. |