DK1103564T3 - Cancerantigener baseret på tumorsuppressorgen WT1-produkt - Google Patents

Cancerantigener baseret på tumorsuppressorgen WT1-produkt

Info

Publication number
DK1103564T3
DK1103564T3 DK99933205T DK99933205T DK1103564T3 DK 1103564 T3 DK1103564 T3 DK 1103564T3 DK 99933205 T DK99933205 T DK 99933205T DK 99933205 T DK99933205 T DK 99933205T DK 1103564 T3 DK1103564 T3 DK 1103564T3
Authority
DK
Denmark
Prior art keywords
product
tumor suppressor
suppressor gene
cancer antigens
antigens based
Prior art date
Application number
DK99933205T
Other languages
Danish (da)
English (en)
Inventor
Haruo Sugiyama
Yoshihiro Oka
Original Assignee
Int Inst Cancer Immunology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16714530&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1103564(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Int Inst Cancer Immunology Inc filed Critical Int Inst Cancer Immunology Inc
Application granted granted Critical
Publication of DK1103564T3 publication Critical patent/DK1103564T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001152—Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464452—Transcription factors, e.g. SOX or c-MYC
    • A61K39/464453—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK99933205T 1998-07-31 1999-07-30 Cancerantigener baseret på tumorsuppressorgen WT1-produkt DK1103564T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21809398 1998-07-31
PCT/JP1999/004130 WO2000006602A1 (fr) 1998-07-31 1999-07-30 Antigenes contre le cancer a base d'un produit du gene suppresseur de tumeur wt1

Publications (1)

Publication Number Publication Date
DK1103564T3 true DK1103564T3 (da) 2009-05-11

Family

ID=16714530

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99933205T DK1103564T3 (da) 1998-07-31 1999-07-30 Cancerantigener baseret på tumorsuppressorgen WT1-produkt

Country Status (15)

Country Link
US (7) US7030212B1 (fr)
EP (3) EP2280031B1 (fr)
JP (2) JP4422903B2 (fr)
KR (1) KR100767554B1 (fr)
CN (4) CN100560130C (fr)
AT (1) ATE420112T1 (fr)
AU (1) AU4932199A (fr)
BR (1) BRPI9912663B8 (fr)
CA (1) CA2337743C (fr)
DE (1) DE69940264D1 (fr)
DK (1) DK1103564T3 (fr)
ES (1) ES2318898T3 (fr)
HK (4) HK1036073A1 (fr)
PT (1) PT1103564E (fr)
WO (1) WO2000006602A1 (fr)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT879282E (pt) 1996-01-17 2003-11-28 Imp College Innovations Ltd Imunoterapia utilizando linfocitos t citotoxicos (ctl)
AU4932199A (en) 1998-07-31 2000-02-21 Haruo Sugiyama Cancer antigens based on tumor suppressor gene wt1 product
US7144581B2 (en) 2000-10-09 2006-12-05 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7115272B1 (en) 1998-09-30 2006-10-03 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7655249B2 (en) 1998-09-30 2010-02-02 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7901693B2 (en) 1998-09-30 2011-03-08 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7063854B1 (en) 1998-09-30 2006-06-20 Corixa Corporation Composition and methods for WTI specific immunotherapy
US7329410B1 (en) 1998-09-30 2008-02-12 Corixa Corporation Compositions and method for WT1 specific immunotherapy
PL201881B1 (pl) * 1998-09-30 2009-05-29 Corixa Corp Izolowany polipeptyd składający się z immunogennej części natywnego WT1, zawierająca go kompozycja farmaceutyczna i szczepionka oraz polinukleotyd kodujący ten polipeptyd
GB9823897D0 (en) * 1998-11-02 1998-12-30 Imp College Innovations Ltd Immunotherapeutic methods and molecules
AU7859900A (en) * 1999-10-04 2001-05-10 Corixa Corporation Compositions and methods for wt1 specific immunotherapy
NZ521430A (en) * 2000-02-22 2004-04-30 Corixa Corp Compositions comprising 1-4 antigenic peptide fragments of the Wilms' tumour gene product for treatment or prevention of malignant mesothelioma
BRPI0208183B8 (pt) 2001-03-22 2021-05-25 Sugiyama Haruo peptídeo antígeno de câncer modificado por wt1 e vacinas para câncer
EP2014300B1 (fr) * 2001-06-29 2011-01-12 Chugai Seiyaku Kabushiki Kaisha Vaccin contre le cancer comprenant un antigène du cancer basé sur le produit d'un gène wt1 suppresseur de tumeur et d'un lipomose cationique
US7553494B2 (en) 2001-08-24 2009-06-30 Corixa Corporation WT1 fusion proteins
WO2003028757A1 (fr) 2001-09-28 2003-04-10 Haruo Sugiyama Nouvelle methode pour induire des lymphocytes t specifiques d'antigenes
US20050002951A1 (en) * 2001-09-28 2005-01-06 Haruo Sugiyama Novel method of inducing antigen-specific t cells
CN101113163B (zh) 2002-06-12 2010-10-06 株式会社国际癌症免疫研究所 Hla-a24限制性癌抗原肽
ES2538486T3 (es) * 2002-09-12 2015-06-22 International Institute Of Cancer Immunology, Inc. Preparación de péptidos antigénicos contra el cáncer
WO2004026897A1 (fr) 2002-09-20 2004-04-01 Chugai Seiyaku Kabushiki Kaisha Peptides de substitution wt1
ATE444969T1 (de) * 2003-01-15 2009-10-15 Int Inst Cancer Immunology Inc Dimerisiertes peptid
CA2530184C (fr) 2003-06-27 2015-10-06 Haruo Sugiyama Methode de selection des patients candidats au vaccin wt1
KR101522079B1 (ko) * 2003-11-05 2015-05-21 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 Ｗｔ１ 유래의 ｈｌａ-ｄｒ 결합성 항원 펩티드
ATE462003T1 (de) 2004-03-31 2010-04-15 Int Inst Cancer Immunology Inc Aus wt1 stammende krebsantigenpeptide
CA2900087C (fr) 2005-10-17 2024-02-13 Sloan Kettering Institute For Cancer Research Peptides de liaison wt1 hla de classe ii, compositions et methodes associees comprenant ces peptides
RU2424247C2 (ru) * 2005-11-30 2011-07-20 Интернэшнл Инститьют Оф Кэнсер Иммьюнолоджи, Инк. Пептид, индуцирующий цитотоксические т-клетки (цтл), способ индукции цтл, антитело, связывающееся с этим пептидом, применение пептида в фармацевтической композиции и для лечения или предупреждения рака, антигенпредставляющая клетка
PL2010209T3 (pl) 2006-04-10 2017-04-28 Sloan Kettering Inst For Cancer Res Immunogeniczne peptydy WT-1 i sposoby ich użycia
GB2440528A (en) * 2006-07-27 2008-02-06 Ist Superiore Sanita Antigen-antibody complexes
US9045556B2 (en) 2007-02-07 2015-06-02 Nec Corporation Therapeutic agent for cancer
MY164867A (en) 2007-02-27 2018-01-30 Int Inst Cancer Immunology Inc Method for activation of helper t cell and composition for use in the method
AU2008222061B2 (en) 2007-03-05 2014-03-20 International Institute Of Cancer Immunology, Inc. Cancer antigen-specific T-cell receptor gene, peptide encoded by the gene, and use of them
CA2881594C (fr) 2007-12-05 2016-04-12 International Institute Of Cancer Immunology, Inc. Composition de vaccin contre le cancer
MX361299B (es) 2010-10-05 2018-11-30 Otsuka Pharmaceutical Co Ltd Star Metodo para activar celulas auxiliares.
EP3447140A3 (fr) 2011-06-28 2019-05-29 International Institute of Cancer Immunology, Inc. Gène récepteur pour un lymphocyte t spécifique d'un antigène cancéreux peptidique
US9539299B2 (en) * 2011-10-27 2017-01-10 International Institute Of Cancer Immunology, Inc. Combination therapy with WT1 peptide vaccine and temozolomide
CA2855358C (fr) 2011-11-11 2021-03-16 Fred Hutchinson Cancer Research Center Immunotherapie par des lymphocytes t ciblant la cycline a1 pour le traitement du cancer
WO2013089252A1 (fr) 2011-12-14 2013-06-20 国立大学法人 高知大学 Modification de polypeptide induisant des cellules t auxiliaires
JP6282598B2 (ja) 2012-01-13 2018-02-21 メモリアル スローン ケタリング キャンサー センター 免疫原性ｗｔ１ペプチド及びその使用方法
US20150150975A1 (en) * 2012-07-02 2015-06-04 Sumitomo Dainippon Pharma Co., Ltd. Transdermal cancer antigen peptide preparation
CN110195040A (zh) 2012-12-17 2019-09-03 大塚制药株式会社 辅助性t细胞的活化方法
US10815273B2 (en) 2013-01-15 2020-10-27 Memorial Sloan Kettering Cancer Center Immunogenic WT-1 peptides and methods of use thereof
EP2945647B1 (fr) 2013-01-15 2020-09-09 Memorial Sloan Kettering Cancer Center Peptides wt-1 immunogènes et leurs procédés d'utilisation
EP2762155B1 (fr) 2013-02-05 2020-03-11 Nitto Denko Corporation Composition vaccinale
RU2014102941A (ru) 2013-02-05 2015-08-10 Нитто Денко Корпорейшн Вакцинная композиция для введения через слизистую оболочку
KR20140100420A (ko) 2013-02-05 2014-08-14 닛토덴코 가부시키가이샤 경피 또는 점막 투여용 백신 조성물
JP6512569B2 (ja) * 2013-02-05 2019-05-15 日東電工株式会社 経皮投与用ｗｔ１ペプチド癌ワクチンテープ剤
CN103961306A (zh) 2013-02-05 2014-08-06 日东电工株式会社 经皮给予用疫苗组合物
KR102045029B1 (ko) 2013-02-05 2019-11-14 닛토덴코 가부시키가이샤 점막 투여용 ｗｔ1 펩티드 암 백신 조성물
JP6512568B2 (ja) * 2013-02-05 2019-05-15 日東電工株式会社 経皮投与用ｗｔ１ペプチド癌ワクチン組成物
US10071051B2 (en) 2013-02-05 2018-09-11 Nitto Denko Corporation WT1 peptide cancer vaccine composition for transdermal administration
EP2974734B1 (fr) * 2013-03-12 2018-10-10 Sumitomo Dainippon Pharma Co., Ltd. Composition aqueuse liquide
JP6671956B2 (ja) 2013-03-29 2020-03-25 大日本住友製薬株式会社 Ｅｒａｐ１によるトリミング機能をきっかけとしたコンジュゲートワクチン
KR102121638B1 (ko) 2013-03-29 2020-06-10 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Wt1 항원 펩티드 콘쥬게이트 백신
WO2016022400A1 (fr) 2014-08-04 2016-02-11 Fred Hutchinson Cancer Research Center Immunothérapie par cellules t spécifiques de la wt-1
DK3199175T3 (da) 2014-09-27 2022-06-13 Sumitomo Pharma Co Ltd Farmaceutisk sammensætning til injektion
JP6947720B2 (ja) * 2015-09-10 2021-10-13 メモリアル スローン ケタリング キャンサー センター Ｔ細胞療法による多発性骨髄腫及び形質細胞白血病の治療方法
EP3377516B1 (fr) 2015-11-20 2022-06-15 Memorial Sloan Kettering Cancer Center Composition pour le traitement du cancer
CN109069599A (zh) * 2016-03-03 2018-12-21 法国古士塔柏罗斯学院 针对癌症的基于ptp的疫苗
WO2018101309A1 (fr) 2016-11-30 2018-06-07 大日本住友製薬株式会社 Peptide auxiliaire wt1, et combinaison dudit peptide et de conjugué peptidique antigénique du cancer
US20210100886A1 (en) 2017-03-30 2021-04-08 Sumitomo Dainippon Pharma Co., Ltd. Wt1 cancer antigen peptides and peptide conjugates comprising the peptides
US20210338587A1 (en) 2018-09-28 2021-11-04 Sumitomo Dainippon Pharma Co., Ltd. Injectable composition
US20220008528A1 (en) * 2018-10-05 2022-01-13 International Institute Of Cancer Immunology, Inc. Composition for preventing or treating benign tumor
TW202045528A (zh) 2019-02-28 2020-12-16 日商大日本住友製藥股份有限公司 選擇可期待用於治療或預防癌之醫藥組合物之效果之對象之方法
JP2022547809A (ja) 2019-08-20 2022-11-16 フレッド ハッチンソン キャンサー センター Ｗｔ－１に特異的なｔ細胞免疫療法
KR20220129567A (ko) 2019-12-31 2022-09-23 엘릭서젠 쎄라퓨틱스, 인크. 핵산 및 단백질의 세포 및 조직으로의 온도-기반 일시적 전달
CA3182959A1 (fr) 2020-05-12 2021-11-18 Sumitomo Pharma Co., Ltd. Composition pharmaceutique pour le traitement du cancer
AU2021272895A1 (en) * 2020-05-12 2022-09-22 Cue Biopharma, Inc. Multimeric T-cell modulatory polypeptides and methods of use thereof
KR20240046880A (ko) 2021-08-12 2024-04-11 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 암을 처치 또는 예방하기 위한 의약 조성물 및 방법

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6122018A (ja) 1984-07-06 1986-01-30 Green Cross Corp:The 癌免疫療法増強剤
JP2546254B2 (ja) 1987-02-23 1996-10-23 澁谷工業株式会社 ガス詰め充填装置
WO1991007509A1 (fr) 1989-11-13 1991-05-30 Massachusetts Institute Of Technology Localisation et caracterisation du gene tumoral de wilms
US5726288A (en) * 1989-11-13 1998-03-10 Massachusetts Institute Of Technology Localization and characterization of the Wilms' tumor gene
CA2069541C (fr) 1992-05-26 2005-02-01 Cornelis J. M. Melief Induction d'une reponse chez des lymphocytes t specifiques de l'antigene
WO1995016464A1 (fr) 1993-12-14 1995-06-22 Johns Hopkins University School Of Medicine Liberation controlee de substances pharmaceutiquement actives pour l'immunotherapie
US5622835A (en) 1994-04-28 1997-04-22 The Wistar Institute Of Anatomy & Biology WT1 monoclonal antibodies
EP1167377B2 (fr) 1994-07-15 2012-08-08 University of Iowa Research Foundation Oliogonucléotides immunomodulateurs
JP3904260B2 (ja) 1995-06-01 2007-04-11 岸本 忠三 ウイルムス腫瘍遺伝子（ｗｔ１）に対するアンチセンスオリゴヌクレオチド誘導体を含んで成る白血病細胞増殖阻害剤
EP0841068B1 (fr) 1995-06-01 2006-07-12 Kishimoto, Tadamitsu Inhibiteur de la croissance de cellules leucemiques contenant des derives oligonucleotidiques antisens agissant contre le gene de la tumeur de wilms (wt1)
DK1435205T3 (da) 1995-09-19 2010-03-29 Bayer Bioscience Gmbh Fremgangsmåde til fremstilling af en modificeret stivelse
JP3060287B2 (ja) 1995-10-09 2000-07-10 参天製薬株式会社 アパファントを主薬とする水性点眼剤
JPH09191635A (ja) 1996-01-05 1997-07-22 Toshio Aida モータ
PT879282E (pt) 1996-01-17 2003-11-28 Imp College Innovations Ltd Imunoterapia utilizando linfocitos t citotoxicos (ctl)
US5840839A (en) * 1996-02-09 1998-11-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
US20030092656A1 (en) 1997-07-16 2003-05-15 Haruo Sugiyama Therapeutic agents for treatment of solid tumors comprising an expression-inhibiting sustance against Wilms' tumor gene (WT1)
JP4789095B2 (ja) 1997-07-16 2011-10-05 治夫 杉山 ウイルムス腫瘍遺伝子（ｗｔ１）に対する発現阻害物質を含んで成る固形腫瘍治療剤
US5985264A (en) 1998-03-05 1999-11-16 The Medical College Of Ohio IL-12 Stimulation of Neonatal immunity
AU4932199A (en) * 1998-07-31 2000-02-21 Haruo Sugiyama Cancer antigens based on tumor suppressor gene wt1 product
PL201881B1 (pl) * 1998-09-30 2009-05-29 Corixa Corp Izolowany polipeptyd składający się z immunogennej części natywnego WT1, zawierająca go kompozycja farmaceutyczna i szczepionka oraz polinukleotyd kodujący ten polipeptyd
US20030235557A1 (en) 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7144581B2 (en) 2000-10-09 2006-12-05 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US20030072767A1 (en) 1998-09-30 2003-04-17 Alexander Gaiger Compositions and methods for WT1 specific immunotherapy
US7063854B1 (en) * 1998-09-30 2006-06-20 Corixa Corporation Composition and methods for WTI specific immunotherapy
US20030039635A1 (en) 1998-09-30 2003-02-27 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7901693B2 (en) 1998-09-30 2011-03-08 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7655249B2 (en) 1998-09-30 2010-02-02 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US20030215458A1 (en) 1998-09-30 2003-11-20 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
GB9823897D0 (en) * 1998-11-02 1998-12-30 Imp College Innovations Ltd Immunotherapeutic methods and molecules
CN1391482A (zh) 1999-01-12 2003-01-15 史密丝克莱恩比彻姆生物有限公司 新型治疗方法
EP1031346B1 (fr) 1999-01-27 2002-05-02 Idea Ag Vaccination non invasive à travers la peau
JP2001089389A (ja) 1999-07-22 2001-04-03 Sumitomo Pharmaceut Co Ltd 抗原特異的ｔ細胞の誘導剤
EP1681064A1 (fr) 1999-07-22 2006-07-19 Dainippon Sumitomo Pharma Co., Ltd. Induction par l'interféron de cellules T spécifiques pour un antigène
NZ521430A (en) 2000-02-22 2004-04-30 Corixa Corp Compositions comprising 1-4 antigenic peptide fragments of the Wilms' tumour gene product for treatment or prevention of malignant mesothelioma
BRPI0208183B8 (pt) 2001-03-22 2021-05-25 Sugiyama Haruo peptídeo antígeno de câncer modificado por wt1 e vacinas para câncer
US7553494B2 (en) 2001-08-24 2009-06-30 Corixa Corporation WT1 fusion proteins
US20050002951A1 (en) 2001-09-28 2005-01-06 Haruo Sugiyama Novel method of inducing antigen-specific t cells
WO2003028757A1 (fr) 2001-09-28 2003-04-10 Haruo Sugiyama Nouvelle methode pour induire des lymphocytes t specifiques d'antigenes
CN101113163B (zh) 2002-06-12 2010-10-06 株式会社国际癌症免疫研究所 Hla-a24限制性癌抗原肽
ES2538486T3 (es) 2002-09-12 2015-06-22 International Institute Of Cancer Immunology, Inc. Preparación de péptidos antigénicos contra el cáncer
WO2004026897A1 (fr) 2002-09-20 2004-04-01 Chugai Seiyaku Kabushiki Kaisha Peptides de substitution wt1
ATE444969T1 (de) 2003-01-15 2009-10-15 Int Inst Cancer Immunology Inc Dimerisiertes peptid
CA2530184C (fr) 2003-06-27 2015-10-06 Haruo Sugiyama Methode de selection des patients candidats au vaccin wt1
KR101522079B1 (ko) 2003-11-05 2015-05-21 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 Ｗｔ１ 유래의 ｈｌａ-ｄｒ 결합성 항원 펩티드
ATE462003T1 (de) 2004-03-31 2010-04-15 Int Inst Cancer Immunology Inc Aus wt1 stammende krebsantigenpeptide

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BRPI9912663A (pt) 2001-05-02
EP2048160A1 (fr) 2009-04-15
US7807792B2 (en) 2010-10-05
KR100767554B1 (ko) 2007-10-17
US20160243209A1 (en) 2016-08-25
US20060093615A1 (en) 2006-05-04
DE69940264D1 (de) 2009-02-26
JP5230579B2 (ja) 2013-07-10
KR20010072112A (ko) 2001-07-31
HK1038929B (zh) 2005-05-06
HK1153761A1 (en) 2012-04-05
BRPI9912663B1 (pt) 2011-05-31
ES2318898T3 (es) 2009-05-01
CN1314916A (zh) 2001-09-26
JP4422903B2 (ja) 2010-03-03
CN100560130C (zh) 2009-11-18
US20090281043A1 (en) 2009-11-12
US20050266014A1 (en) 2005-12-01
EP1103564A1 (fr) 2001-05-30
BRPI9912663B8 (pt) 2021-07-06
CA2337743C (fr) 2015-07-07
US7517950B2 (en) 2009-04-14
HK1130069A1 (en) 2009-12-18
US7030212B1 (en) 2006-04-18
CN1560078B (zh) 2011-06-22
US20090143291A1 (en) 2009-06-04
US7608685B1 (en) 2009-10-27
HK1038929A1 (en) 2002-04-04
US7390871B2 (en) 2008-06-24
JP2010059172A (ja) 2010-03-18
CN102198266A (zh) 2011-09-28
CA2337743A1 (fr) 2000-02-10
US9403886B2 (en) 2016-08-02
CN1560078A (zh) 2005-01-05
CN1178956C (zh) 2004-12-08
WO2000006602A1 (fr) 2000-02-10
EP2280031B1 (fr) 2015-04-15
EP2280031A1 (fr) 2011-02-02
AU4932199A (en) 2000-02-21
CN1762490A (zh) 2006-04-26
EP1103564B1 (fr) 2009-01-07
ATE420112T1 (de) 2009-01-15
EP1103564A4 (fr) 2005-02-02
HK1036073A1 (en) 2001-12-21
PT1103564E (pt) 2009-03-13
EP2048160B1 (fr) 2015-01-07

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