ATE462003T1 - Aus wt1 stammende krebsantigenpeptide - Google Patents

Aus wt1 stammende krebsantigenpeptide

Info

Publication number
ATE462003T1
ATE462003T1 AT05727848T AT05727848T ATE462003T1 AT E462003 T1 ATE462003 T1 AT E462003T1 AT 05727848 T AT05727848 T AT 05727848T AT 05727848 T AT05727848 T AT 05727848T AT E462003 T1 ATE462003 T1 AT E462003T1
Authority
AT
Austria
Prior art keywords
peptides derived
cancer antigen
antigen peptides
peptide
cancer
Prior art date
Application number
AT05727848T
Other languages
English (en)
Inventor
Haruo Sugiyama
Original Assignee
Int Inst Cancer Immunology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Inst Cancer Immunology Inc filed Critical Int Inst Cancer Immunology Inc
Application granted granted Critical
Publication of ATE462003T1 publication Critical patent/ATE462003T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4242—Transcription factors, e.g. SOX or c-MYC
    • A61K40/4243—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
AT05727848T 2004-03-31 2005-03-30 Aus wt1 stammende krebsantigenpeptide ATE462003T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004105219 2004-03-31
PCT/JP2005/006113 WO2005095598A1 (ja) 2004-03-31 2005-03-30 Ｗｔ１由来の癌抗原ペプチド

Publications (1)

Publication Number Publication Date
ATE462003T1 true ATE462003T1 (de) 2010-04-15

Family

ID=35063778

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05727848T ATE462003T1 (de) 2004-03-31 2005-03-30 Aus wt1 stammende krebsantigenpeptide

Country Status (11)

Country Link
US (3) US7622119B2 (de)
EP (2) EP2186896B1 (de)
JP (1) JP4886507B2 (de)
AT (1) ATE462003T1 (de)
DE (1) DE602005020121D1 (de)
DK (2) DK1731605T3 (de)
ES (2) ES2341785T3 (de)
PL (1) PL1731605T3 (de)
PT (1) PT1731605E (de)
SI (1) SI1731605T1 (de)
WO (1) WO2005095598A1 (de)

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US7030212B1 (en) 1998-07-31 2006-04-18 Haruo Sugiyama Tumor antigen based on products of the tumor suppressor gene WT1
ATE383375T1 (de) 2001-03-22 2008-01-15 Int Inst Cancer Immunology Inc Wti-modifiziertes peptid
EP1447091A4 (de) * 2001-09-28 2008-02-13 Institute Of Can International Neues verfahren zur induktion von antigen-spezifischen t-zellen
ES2538486T3 (es) * 2002-09-12 2015-06-22 International Institute Of Cancer Immunology, Inc. Preparación de péptidos antigénicos contra el cáncer
KR101399678B1 (ko) 2003-01-15 2014-05-27 추가이 세이야쿠 가부시키가이샤 이량체화 펩티드
KR101431312B1 (ko) * 2003-06-27 2014-08-20 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 Ｗｔ1 백신 적응 환자의 선택 방법
SI2071028T1 (sl) 2003-11-05 2012-03-30 Int Inst Cancer Immunology Inc Antigen peptid pridobljen iz WT ki veže HLA DR
ES2341785T3 (es) * 2004-03-31 2010-06-28 International Institute Of Cancer Immunology, Inc. Peptidos antigenicos del cancer derivados de wt1.
CA2626238C (en) 2005-10-17 2015-10-06 Sloan Kettering Institute For Cancer Research Wt1 hla class ii-binding peptides and compositions and methods comprising same
DK1961761T3 (da) * 2005-11-30 2010-11-29 Int Inst Cancer Immunology Inc Hidtil ukendte peptidforbindelser fra Wilms' tumor
CN102702319B (zh) 2006-02-22 2015-01-28 株式会社癌免疫研究所 Hla-a*3303限制性wt1肽和包含此肽的药物组合物
PL2010209T3 (pl) 2006-04-10 2017-04-28 Sloan Kettering Inst For Cancer Res Immunogeniczne peptydy WT-1 i sposoby ich użycia
CA2886622A1 (en) 2006-12-28 2008-07-10 International Institute Of Cancer Immunology, Inc. Hla-a*1101-restricted wt1 peptide and pharmaceutical composition comprising the same
NZ599160A (en) 2007-02-27 2012-07-27 Int Inst Cancer Immunology Inc Method for activation of helper t cell and composition for use in the method
MX343633B (es) 2007-03-05 2016-11-11 Int Inst Cancer Immunology Inc Gen receptor de celulas t especificas de antigeno cancerigeno, peptido codificado por el gen, y uso de los mismos.
EP2216041A4 (de) * 2007-11-20 2012-10-24 Nec Corp Verfahren zur induktion einer zytotoxischen t-zelle, zytotoxischer t-zell-induktor und pharmazeutische zusammensetzung sowie impfstoff mit dem induktor
KR20110053836A (ko) * 2009-11-16 2011-05-24 삼성에스디아이 주식회사 리튬 폴리머 이차 전지
US10654892B2 (en) 2010-10-05 2020-05-19 International Institute Of Cancer Immunology, Inc. Method for activating helper T cell
AU2012276908A1 (en) 2011-06-28 2014-02-20 International Institute Of Cancer Immunology, Inc. Receptor gene for peptide cancer antigen-specific T cell
US9539299B2 (en) * 2011-10-27 2017-01-10 International Institute Of Cancer Immunology, Inc. Combination therapy with WT1 peptide vaccine and temozolomide
CN104080797A (zh) 2011-11-11 2014-10-01 弗雷德哈钦森癌症研究中心 针对癌症的靶向细胞周期蛋白a1的t细胞免疫疗法
US20150104413A1 (en) 2012-01-13 2015-04-16 Memorial Sloan Kettering Cancer Center Immunogenic wt-1 peptides and methods of use thereof
EP3495483A1 (de) 2012-09-12 2019-06-12 International Institute of Cancer Immunology, Inc. Antigenspezifische helfer-t-zell-rezeptorgene
JP6530192B2 (ja) 2012-12-17 2019-06-12 大塚製薬株式会社 ヘルパーｔ細胞の活性化方法
DK2945647T3 (da) 2013-01-15 2020-11-16 Memorial Sloan Kettering Cancer Center Immunogene wt-1-peptider og anvendelsesmetoder deraf
US10815273B2 (en) 2013-01-15 2020-10-27 Memorial Sloan Kettering Cancer Center Immunogenic WT-1 peptides and methods of use thereof
CA2840988A1 (en) 2013-02-05 2014-08-05 Nitto Denko Corporation Wt1 peptide cancer vaccine composition for mucosal administration
KR20140100417A (ko) 2013-02-05 2014-08-14 닛토덴코 가부시키가이샤 경피 투여용 백신 조성물
CA2840974A1 (en) 2013-02-05 2014-08-05 Nitto Denko Corporation Vaccine composition for mucosal administration
IN2014CH00396A (de) 2013-02-05 2015-04-03 Nitto Denko Corp
RU2697443C2 (ru) 2013-02-05 2019-08-14 Нитто Денко Корпорейшн Препарат противораковой вакцины, содержащий пептид wt1, в форме ленты трансдермального введения
KR20140100416A (ko) 2013-02-05 2014-08-14 닛토덴코 가부시키가이샤 경피 투여용 ｗｔ1 펩티드 암 백신 조성물
EP2762157A1 (de) 2013-02-05 2014-08-06 Nitto Denko Corporation Impfstoffzusammensetzung zur transdermalen oder mukosalen Verabreichung
US10449144B2 (en) 2013-02-05 2019-10-22 Nitto Denko Corporation WT1 peptide cancer vaccine composition for transdermal administration
US10023841B2 (en) * 2014-05-23 2018-07-17 Baylor Research Institute Methods and compositions for treating breast cancer with dendritic cell vaccines
CA2956545A1 (en) 2014-08-04 2016-02-11 Fred Hutchinson Cancer Research Center T cell immunotherapy specific for wt-1
HK1243960A1 (zh) 2014-12-25 2018-07-27 International Institute Of Cancer Immunology, Inc. T细胞群的改变方法
GB201504502D0 (en) * 2015-03-17 2015-04-29 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
CN106610423A (zh) * 2015-10-26 2017-05-03 复旦大学 评价疫苗疗效的细胞免疫学检测试剂盒及其储存方法
ES2946188T3 (es) 2016-11-09 2023-07-13 Univ Osaka Procedimiento para modificar una población de linfocitos T
US12259379B2 (en) 2017-06-30 2025-03-25 Osaka University Method for predicting effect of tumor immunotherapy using tumor cytotoxic activity of peripheral blood T cells as index
JP7611844B2 (ja) 2019-03-11 2025-01-10 フレッド ハッチンソン キャンサー センター 高アビディティｗｔ１ｔ細胞受容体とその使用
EP4017872A1 (de) 2019-08-20 2022-06-29 Fred Hutchinson Cancer Center Wt-1-spezifische t-zell-immuntherapie
CN111978375B (zh) * 2020-08-28 2022-10-04 深圳市乐土生物医药有限公司 具有细胞毒性t细胞诱导能力的蛋白质或多肽
CN112250752B (zh) * 2020-12-21 2021-03-26 中生康元生物科技(北京)有限公司 肿瘤新抗原表位肽及其应用
WO2022140388A1 (en) 2020-12-21 2022-06-30 Allogene Therapeutics, Inc. Protease-activating cd45-gate car
CA3204417A1 (en) 2021-01-29 2022-08-04 Allogene Therapeutics, Inc. Knockdown or knockout of one or more of tap2, nlrc5, ?2m, trac, rfx5, rfxap and rfxank to mitigate t cell recognition of allogeneic cell products
EP4562134A1 (de) 2022-07-29 2025-06-04 Allogene Therapeutics, Inc. Manipulierte zellen mit reduzierter genexpression zur abschwächung der immunzellenerkennung
WO2025096560A1 (en) 2023-10-30 2025-05-08 Allogene Therapeutics, Inc. Engineered cells

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ATE399179T1 (de) 1998-09-30 2008-07-15 Corixa Corp Zusammensetzungen und verfahren für wt1- spezifische immunotherapie
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ATE383375T1 (de) * 2001-03-22 2008-01-15 Int Inst Cancer Immunology Inc Wti-modifiziertes peptid
EP1447092A4 (de) * 2001-09-28 2007-07-11 Haruo Sugiyama Neues verfahren zur induktion von antigenspezifischen t-zellen
EP1447091A4 (de) * 2001-09-28 2008-02-13 Institute Of Can International Neues verfahren zur induktion von antigen-spezifischen t-zellen
DE60332355D1 (de) * 2002-06-12 2010-06-10 Chugai Pharmaceutical Co Ltd Hla-a24-restringiertes krebsantigenpeptid
ES2538486T3 (es) * 2002-09-12 2015-06-22 International Institute Of Cancer Immunology, Inc. Preparación de péptidos antigénicos contra el cáncer
WO2004026897A1 (ja) * 2002-09-20 2004-04-01 Chugai Seiyaku Kabushiki Kaisha Ｗｔ１置換型ペプチド
KR101399678B1 (ko) * 2003-01-15 2014-05-27 추가이 세이야쿠 가부시키가이샤 이량체화 펩티드
KR101431312B1 (ko) * 2003-06-27 2014-08-20 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 Ｗｔ1 백신 적응 환자의 선택 방법
SI2071028T1 (sl) * 2003-11-05 2012-03-30 Int Inst Cancer Immunology Inc Antigen peptid pridobljen iz WT ki veže HLA DR
ES2341785T3 (es) * 2004-03-31 2010-06-28 International Institute Of Cancer Immunology, Inc. Peptidos antigenicos del cancer derivados de wt1.

Also Published As

Publication number Publication date
PL1731605T3 (pl) 2010-08-31
DE602005020121D1 (de) 2010-05-06
ES2341785T3 (es) 2010-06-28
JP4886507B2 (ja) 2012-02-29
EP2186896A1 (de) 2010-05-19
WO2005095598A1 (ja) 2005-10-13
US7622119B2 (en) 2009-11-24
JPWO2005095598A1 (ja) 2008-02-21
EP1731605A1 (de) 2006-12-13
US8388975B2 (en) 2013-03-05
US20130196427A1 (en) 2013-08-01
US20080152631A1 (en) 2008-06-26
PT1731605E (pt) 2010-04-14
EP1731605A4 (de) 2007-11-07
EP2186896B1 (de) 2015-11-04
SI1731605T1 (sl) 2010-07-30
US20100062013A1 (en) 2010-03-11
DK2186896T3 (en) 2015-12-21
ES2556232T3 (es) 2016-01-14
DK1731605T3 (da) 2010-05-25
HK1144305A1 (en) 2011-02-11
EP1731605B1 (de) 2010-03-24

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