ATE497975T1 - Il-21-varianten - Google Patents

Il-21-varianten

Info

Publication number
ATE497975T1
ATE497975T1 AT06763042T AT06763042T ATE497975T1 AT E497975 T1 ATE497975 T1 AT E497975T1 AT 06763042 T AT06763042 T AT 06763042T AT 06763042 T AT06763042 T AT 06763042T AT E497975 T1 ATE497975 T1 AT E497975T1
Authority
AT
Austria
Prior art keywords
amino acids
variants
deleting
seq
peptide
Prior art date
Application number
AT06763042T
Other languages
English (en)
Inventor
Siv Hjorth
Kent Bodensgaard
Dennis Madsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE497975T1 publication Critical patent/ATE497975T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT06763042T 2005-04-18 2006-04-18 Il-21-varianten ATE497975T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500562 2005-04-18
PCT/EP2006/061635 WO2006111524A2 (en) 2005-04-18 2006-04-18 Il-21 variants

Publications (1)

Publication Number Publication Date
ATE497975T1 true ATE497975T1 (de) 2011-02-15

Family

ID=36950214

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06763042T ATE497975T1 (de) 2005-04-18 2006-04-18 Il-21-varianten

Country Status (17)

Country Link
US (2) US8034326B2 (de)
EP (2) EP1877439B1 (de)
JP (2) JP2008538290A (de)
KR (1) KR20080013878A (de)
CN (1) CN101180315A (de)
AT (1) ATE497975T1 (de)
AU (1) AU2006237329B2 (de)
BR (1) BRPI0609079A2 (de)
CA (1) CA2604222A1 (de)
DE (1) DE602006020032D1 (de)
ES (1) ES2357550T3 (de)
IL (1) IL186265A0 (de)
MX (1) MX2007012887A (de)
NO (1) NO20075927L (de)
RU (1) RU2412199C2 (de)
WO (1) WO2006111524A2 (de)
ZA (1) ZA200708407B (de)

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US20060228331A1 (en) 2003-10-10 2006-10-12 Novo Nordisk A/S IL-21 Derivatives and variants
RU2412199C2 (ru) * 2005-04-18 2011-02-20 Ново Нордиск А/С Варианты ил-21
CN101553501A (zh) * 2006-10-26 2009-10-07 诺沃-诺迪斯克有限公司 Il-21变种
EP2109620B1 (de) 2006-12-21 2012-08-22 Novo Nordisk A/S Interleukin-21-varianten mit geänderter bindung an den il-21-rezeptor
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EP2384337A1 (de) * 2009-01-05 2011-11-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Mittel und verfahren zur behandlung von auf il-21 und il-21-varianten basierenden antikörpermangelkrankheiten
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US9959384B2 (en) 2013-12-10 2018-05-01 Bioniz, Llc Methods of developing selective peptide antagonists
CN108350032A (zh) 2015-10-09 2018-07-31 比奥尼斯有限责任公司 调节γC-细胞因子活性
CN109153728A (zh) * 2016-03-21 2019-01-04 埃尔斯塔治疗公司 多特异性和多功能分子及其用途
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CN111205361B (zh) * 2018-11-22 2022-05-06 海珂分子（北京）科技有限责任公司 白介素21蛋白(il21)突变体及其应用
CN115232797A (zh) * 2021-04-23 2022-10-25 南京北恒生物科技有限公司 工程化免疫细胞及其用途
EP4340866A1 (de) * 2021-05-19 2024-03-27 Asher Biotherapeutics, Inc. Il-21-polypeptide und gezielte konstrukte
KR20230157760A (ko) * 2022-05-10 2023-11-17 아주대학교산학협력단 인터루킨21 변이체, 이를 포함하는 융합단백질 및 이의 용도
WO2024002170A1 (en) * 2022-06-29 2024-01-04 Beijing Neox Biotech Limited Il-21 polypeptides and methods of use

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Also Published As

Publication number Publication date
DE602006020032D1 (de) 2011-03-24
US20120082996A1 (en) 2012-04-05
RU2007136026A (ru) 2009-05-27
WO2006111524A2 (en) 2006-10-26
US20090035254A1 (en) 2009-02-05
EP1877439B1 (de) 2011-02-09
MX2007012887A (es) 2007-12-10
CN101180315A (zh) 2008-05-14
JP2012070742A (ja) 2012-04-12
NO20075927L (no) 2007-12-07
KR20080013878A (ko) 2008-02-13
AU2006237329A1 (en) 2006-10-26
RU2412199C2 (ru) 2011-02-20
IL186265A0 (en) 2008-01-20
US8383367B2 (en) 2013-02-26
ES2357550T3 (es) 2011-04-27
EP2360181B1 (de) 2013-09-18
CA2604222A1 (en) 2006-10-26
JP2008538290A (ja) 2008-10-23
US8034326B2 (en) 2011-10-11
EP1877439A2 (de) 2008-01-16
EP2360181A1 (de) 2011-08-24
BRPI0609079A2 (pt) 2010-11-16
WO2006111524A3 (en) 2006-12-07
AU2006237329B2 (en) 2012-04-12
ZA200708407B (en) 2008-10-29

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