ATE444969T1 - Dimerisiertes peptid - Google Patents
Dimerisiertes peptidInfo
- Publication number
- ATE444969T1 ATE444969T1 AT04702444T AT04702444T ATE444969T1 AT E444969 T1 ATE444969 T1 AT E444969T1 AT 04702444 T AT04702444 T AT 04702444T AT 04702444 T AT04702444 T AT 04702444T AT E444969 T1 ATE444969 T1 AT E444969T1
- Authority
- AT
- Austria
- Prior art keywords
- peptide
- tumor antigen
- dimerized peptide
- antigen peptide
- dimerized
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229940022399 cancer vaccine Drugs 0.000 abstract 1
- 238000009566 cancer vaccine Methods 0.000 abstract 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 1
- 239000000539 dimer Substances 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003007122 | 2003-01-15 | ||
| PCT/JP2004/000254 WO2004063217A1 (ja) | 2003-01-15 | 2004-01-15 | 二量体化ペプチド |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE444969T1 true ATE444969T1 (de) | 2009-10-15 |
Family
ID=32709100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04702444T ATE444969T1 (de) | 2003-01-15 | 2004-01-15 | Dimerisiertes peptid |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20060217297A1 (de) |
| EP (2) | EP2154145B1 (de) |
| JP (2) | JP4498274B2 (de) |
| KR (2) | KR101399678B1 (de) |
| CN (2) | CN101851275A (de) |
| AT (1) | ATE444969T1 (de) |
| AU (1) | AU2004204031B2 (de) |
| BR (1) | BRPI0406800B8 (de) |
| CA (1) | CA2513701C (de) |
| DE (1) | DE602004023476D1 (de) |
| ES (1) | ES2332590T3 (de) |
| WO (1) | WO2004063217A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4932199A (en) * | 1998-07-31 | 2000-02-21 | Haruo Sugiyama | Cancer antigens based on tumor suppressor gene wt1 product |
| CN1281625C (zh) * | 2001-03-22 | 2006-10-25 | 株式会社癌免疫研究所 | 经修饰的wt1肽 |
| US8021658B2 (en) * | 2001-05-25 | 2011-09-20 | Thomas Jefferson University | Alternative splice forms of proteins as basis for multiple therapeutic modalities |
| EP1550453B1 (de) * | 2002-09-12 | 2015-05-27 | International Institute of Cancer Immunology, Inc. | Präparat eines peptids eines krebs-antigens |
| WO2005045027A1 (ja) | 2003-11-05 | 2005-05-19 | International Institute Of Cancer Immunology, Inc. | Ｗｔ１由来のｈｌａ−ｄｒ結合性抗原ペプチド |
| PT1731605E (pt) * | 2004-03-31 | 2010-04-14 | Int Inst Cancer Immunology Inc | Péptidos antigénicos de cancro derivados de wt1 |
| DK1853305T3 (en) * | 2005-02-04 | 2014-12-01 | Survac Aps | Survivin-peptide vaccine |
| SI1961761T1 (sl) * | 2005-11-30 | 2010-12-31 | Int Inst Cancer Immunology Inc | Nove peptidne spojine iz Wilmsovega tumorja |
| RU2435782C2 (ru) | 2006-02-22 | 2011-12-10 | Интернешнл Инститьют Оф Кэнсер Иммунолоджи, Инк. | Hla-a*3303-рестриктированный пептид wt1 и содержащая его фармацевтическая композиция |
| DK1987063T3 (da) * | 2006-02-23 | 2010-01-04 | Fibrex Medical Res & Dev Gmbh | Peptider og peptidderivater, fremstilling deraf samt deres anvendelse til fremstilling af en terapeutisk og/eller præventivt aktiv farmaceutisk sammensætning |
| RU2481398C2 (ru) * | 2006-12-28 | 2013-05-10 | Интернешнл Инститьют Оф Кэнсер Иммунолоджи, Инк. | Hla-a*1101-ограниченный пептид wt1 и содержащая его фармацевтическая композиция |
| MX352947B (es) | 2007-02-27 | 2017-12-14 | Int Inst Cancer Immunology Inc | Metodo para activacion de celula t auxiliar y composicion para usarse en el metodo. |
| PT2193142E (pt) * | 2007-08-30 | 2015-04-22 | Curedm Group Holdings Llc | Composições e procedimentos de utilização de peptídeos pro-ilhota e seus análogos |
| SG189287A1 (en) | 2010-10-05 | 2013-05-31 | Int Inst Cancer Immunology Inc | Method for activating helper t cell |
| JP6069212B2 (ja) * | 2010-12-02 | 2017-02-01 | ビオノール イミュノ エーエスＢｉｏｎｏｒ Ｉｍｍｕｎｏ Ａｓ | ペプチド骨格設計 |
| CA2822684A1 (en) * | 2010-12-23 | 2012-06-28 | Intercell Austria Ag | Oprf/i agents and their use in hospitalized and other patients |
| JP6294076B2 (ja) | 2011-01-06 | 2018-03-14 | ビオノール イミュノ エーエスＢｉｏｎｏｒ Ｉｍｍｕｎｏ Ａｓ | 多量体ペプチド |
| JP6082901B2 (ja) * | 2011-01-31 | 2017-02-22 | オリンパス株式会社 | ワクチン・アジュバント |
| EP2868325B1 (de) | 2012-07-02 | 2017-11-01 | Sumitomo Dainippon Pharma Co., Ltd. | Transdermales krebs-antigen-peptidpräparat |
| AR094026A1 (es) | 2012-12-17 | 2015-07-08 | Otsuka Pharma Co Ltd | Metodo para activar la celula t helper |
| EP2974734B1 (de) | 2013-03-12 | 2018-10-10 | Sumitomo Dainippon Pharma Co., Ltd. | Flüssige, wässrige zusammensetzung |
| JP6671956B2 (ja) * | 2013-03-29 | 2020-03-25 | 大日本住友製薬株式会社 | Ｅｒａｐ１によるトリミング機能をきっかけとしたコンジュゲートワクチン |
| WO2014157692A1 (ja) | 2013-03-29 | 2014-10-02 | 大日本住友製薬株式会社 | Ｗｔ１抗原ペプチドコンジュゲートワクチン |
| WO2015057009A1 (ko) | 2013-10-17 | 2015-04-23 | 서울대학교산학협력단 | 알파나선형 세포 투과 펩타이드 다합체, 이의 제조방법 및 그 용도 |
| JP6580581B2 (ja) * | 2014-09-27 | 2019-09-25 | 大日本住友製薬株式会社 | 注射用医薬組成物 |
| JP6671141B2 (ja) * | 2014-10-21 | 2020-03-25 | 大日本住友製薬株式会社 | 懸濁液剤 |
| ES2993462T3 (en) * | 2015-05-20 | 2024-12-30 | Sumitomo Pharma Co Ltd | Combination of wt1 antigen peptide, immunomodulator and wt1 helper peptide |
| JP2018524595A (ja) * | 2015-07-14 | 2018-08-30 | イエダ リサーチ アンド ディベロップメント カンパニー リミテッド | 統合失調症の診断で使用するためのペプチドの組み合わせ |
| WO2018101309A1 (ja) | 2016-11-30 | 2018-06-07 | 大日本住友製薬株式会社 | Ｗｔ１ヘルパーペプチド及びこれと癌抗原ペプチドコンジュゲート体との組合せ |
| JPWO2019131722A1 (ja) * | 2017-12-27 | 2021-01-14 | 大日本住友製薬株式会社 | Ｗｔ１由来ペプチドのコンジュゲート体およびこれを含む組成物 |
| US12233130B2 (en) | 2022-12-22 | 2025-02-25 | Defence Therapeutics Inc. | Covalently-modified steroid acid-peptides having enhanced stability and/or biological activity |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2268705T3 (es) * | 1995-06-01 | 2007-03-16 | Kishimoto, Tadamitsu | Inhibidor del crecimiento de celulas leucemicas que contienen un derivado oligonucleotidico antisentido frente al gen del tumor de wiloms (wt1). |
| JP3060287B2 (ja) | 1995-10-09 | 2000-07-10 | 参天製薬株式会社 | アパファントを主薬とする水性点眼剤 |
| AU4932199A (en) * | 1998-07-31 | 2000-02-21 | Haruo Sugiyama | Cancer antigens based on tumor suppressor gene wt1 product |
| US7063854B1 (en) * | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
| KR100752065B1 (ko) * | 1998-09-30 | 2007-08-28 | 코릭사 코포레이션 | Ｗｔ1 특이적 면역요법용 조성물 및 방법 |
| GB9823897D0 (en) * | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
| JPWO2002047474A1 (ja) | 2000-12-13 | 2004-04-15 | 住友製薬株式会社 | Ｈｌａ−ａ２４発現トランスジェニック動物及びその利用 |
| CN1281625C (zh) | 2001-03-22 | 2006-10-25 | 株式会社癌免疫研究所 | 经修饰的wt1肽 |
| US8735357B2 (en) * | 2001-09-28 | 2014-05-27 | International Institute Of Cancer Immunology, Inc. | Method of inducing antigen-specific T cells |
| EP1447092A4 (de) * | 2001-09-28 | 2007-07-11 | Haruo Sugiyama | Neues verfahren zur induktion von antigenspezifischen t-zellen |
| WO2003106682A1 (ja) * | 2002-06-12 | 2003-12-24 | 中外製薬株式会社 | Ｈｌａ−ａ２４拘束性癌抗原ペプチド |
| WO2005045027A1 (ja) | 2003-11-05 | 2005-05-19 | International Institute Of Cancer Immunology, Inc. | Ｗｔ１由来のｈｌａ−ｄｒ結合性抗原ペプチド |
| PT1731605E (pt) | 2004-03-31 | 2010-04-14 | Int Inst Cancer Immunology Inc | Péptidos antigénicos de cancro derivados de wt1 |
-
2004
- 2004-01-15 EP EP09172205.8A patent/EP2154145B1/de not_active Expired - Lifetime
- 2004-01-15 AU AU2004204031A patent/AU2004204031B2/en not_active Expired
- 2004-01-15 ES ES04702444T patent/ES2332590T3/es not_active Expired - Lifetime
- 2004-01-15 WO PCT/JP2004/000254 patent/WO2004063217A1/ja not_active Ceased
- 2004-01-15 CN CN201010156098A patent/CN101851275A/zh active Pending
- 2004-01-15 DE DE602004023476T patent/DE602004023476D1/de not_active Expired - Lifetime
- 2004-01-15 EP EP04702444A patent/EP1584627B1/de not_active Expired - Lifetime
- 2004-01-15 US US10/541,821 patent/US20060217297A1/en not_active Abandoned
- 2004-01-15 AT AT04702444T patent/ATE444969T1/de not_active IP Right Cessation
- 2004-01-15 KR KR1020057012761A patent/KR101399678B1/ko not_active Expired - Lifetime
- 2004-01-15 KR KR1020127008760A patent/KR20120054644A/ko not_active Withdrawn
- 2004-01-15 BR BRPI0406800A patent/BRPI0406800B8/pt not_active IP Right Cessation
- 2004-01-15 CA CA2513701A patent/CA2513701C/en not_active Expired - Lifetime
- 2004-01-15 JP JP2005508011A patent/JP4498274B2/ja not_active Expired - Lifetime
- 2004-01-15 CN CN2004800058473A patent/CN1756763B/zh not_active Expired - Lifetime
-
2009
- 2009-11-16 JP JP2009260957A patent/JP4926231B2/ja not_active Expired - Lifetime
-
2010
- 2010-06-07 US US12/795,187 patent/US8242084B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20060217297A1 (en) | 2006-09-28 |
| JPWO2004063217A1 (ja) | 2006-06-01 |
| KR101399678B1 (ko) | 2014-05-27 |
| EP2154145A3 (de) | 2010-05-19 |
| JP2010047603A (ja) | 2010-03-04 |
| US20100292164A1 (en) | 2010-11-18 |
| JP4498274B2 (ja) | 2010-07-07 |
| CA2513701A1 (en) | 2004-07-29 |
| KR20120054644A (ko) | 2012-05-30 |
| EP2154145A2 (de) | 2010-02-17 |
| BRPI0406800B1 (pt) | 2020-08-11 |
| JP4926231B2 (ja) | 2012-05-09 |
| BRPI0406800A8 (pt) | 2016-11-01 |
| EP1584627B1 (de) | 2009-10-07 |
| ES2332590T3 (es) | 2010-02-09 |
| HK1141539A1 (en) | 2010-11-12 |
| EP1584627A4 (de) | 2006-03-15 |
| AU2004204031B2 (en) | 2010-03-04 |
| CN1756763A (zh) | 2006-04-05 |
| DE602004023476D1 (de) | 2009-11-19 |
| BRPI0406800B8 (pt) | 2021-05-25 |
| CN1756763B (zh) | 2010-05-26 |
| AU2004204031A1 (en) | 2004-07-29 |
| CA2513701C (en) | 2013-06-18 |
| US8242084B2 (en) | 2012-08-14 |
| EP1584627A1 (de) | 2005-10-12 |
| HK1081975A1 (en) | 2006-05-26 |
| BRPI0406800A (pt) | 2006-01-17 |
| WO2004063217A1 (ja) | 2004-07-29 |
| EP2154145B1 (de) | 2013-04-24 |
| CN101851275A (zh) | 2010-10-06 |
| KR20050098863A (ko) | 2005-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |