DK1059933T3 - Anvendelse af parathyroideahormon bestående af aminosyresekvens 1-34 af humant parathyroideahormon til reduktion af risikoen for både hvirvel- og ikke-hvirvel knoglefraktur - Google Patents

Anvendelse af parathyroideahormon bestående af aminosyresekvens 1-34 af humant parathyroideahormon til reduktion af risikoen for både hvirvel- og ikke-hvirvel knoglefraktur

Info

Publication number
DK1059933T3
DK1059933T3 DK99942350T DK99942350T DK1059933T3 DK 1059933 T3 DK1059933 T3 DK 1059933T3 DK 99942350 T DK99942350 T DK 99942350T DK 99942350 T DK99942350 T DK 99942350T DK 1059933 T3 DK1059933 T3 DK 1059933T3
Authority
DK
Denmark
Prior art keywords
parathyroid hormone
vertebral
risk
amino acid
acid sequence
Prior art date
Application number
DK99942350T
Other languages
Danish (da)
English (en)
Inventor
Janet M Hock
Gregory A Gaich
Willard H Dere
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26792729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1059933(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK1059933T3 publication Critical patent/DK1059933T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Steroid Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
DK99942350T 1998-08-19 1999-08-19 Anvendelse af parathyroideahormon bestående af aminosyresekvens 1-34 af humant parathyroideahormon til reduktion af risikoen for både hvirvel- og ikke-hvirvel knoglefraktur DK1059933T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9715198P 1998-08-19 1998-08-19
US9974698P 1998-09-10 1998-09-10
PCT/US1999/018961 WO2000010596A1 (en) 1998-08-19 1999-08-19 Method of increasing bone toughness and stiffness and reducing fractures

Publications (1)

Publication Number Publication Date
DK1059933T3 true DK1059933T3 (da) 2003-04-07

Family

ID=26792729

Family Applications (4)

Application Number Title Priority Date Filing Date
DK10180447.4T DK2266598T3 (en) 1998-08-19 1999-08-19 Procedure to increase bone hardness and stiffness and to reduce fractures
DK15152726.4T DK2907522T3 (en) 1998-08-19 1999-08-19 Procedure for increasing bone hardness and stiffness and reduction of fractures
DK99942350T DK1059933T3 (da) 1998-08-19 1999-08-19 Anvendelse af parathyroideahormon bestående af aminosyresekvens 1-34 af humant parathyroideahormon til reduktion af risikoen for både hvirvel- og ikke-hvirvel knoglefraktur
DK06027055.0T DK1769804T3 (da) 1998-08-19 1999-08-19 hPTH(1-34) til anvendelse ved forebyggelse eller reduktion af forekomsten eller voldsomheden af vertebral og/eller ikke-vertebral fraktur hos en mand

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK10180447.4T DK2266598T3 (en) 1998-08-19 1999-08-19 Procedure to increase bone hardness and stiffness and to reduce fractures
DK15152726.4T DK2907522T3 (en) 1998-08-19 1999-08-19 Procedure for increasing bone hardness and stiffness and reduction of fractures

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK06027055.0T DK1769804T3 (da) 1998-08-19 1999-08-19 hPTH(1-34) til anvendelse ved forebyggelse eller reduktion af forekomsten eller voldsomheden af vertebral og/eller ikke-vertebral fraktur hos en mand

Country Status (33)

Country Link
US (2) US6977077B1 (el)
EP (3) EP1059933B1 (el)
JP (5) JP2002523375A (el)
KR (1) KR100454207B1 (el)
CN (1) CN1205997C (el)
AR (1) AR033639A1 (el)
AT (1) ATE231000T1 (el)
AU (1) AU746277B2 (el)
BR (1) BR9909445A (el)
CA (1) CA2325371C (el)
CO (1) CO5130020A1 (el)
CY (2) CY1113343T1 (el)
CZ (1) CZ301017B6 (el)
DE (2) DE15152726T1 (el)
DK (4) DK2266598T3 (el)
DZ (1) DZ2873A1 (el)
EA (1) EA003362B1 (el)
ES (4) ES2621653T3 (el)
HK (3) HK1030545A1 (el)
HR (1) HRP20000755A2 (el)
HU (2) HU230697B1 (el)
ID (1) ID29039A (el)
IL (2) IL138829A0 (el)
MY (1) MY129227A (el)
NO (2) NO323984B1 (el)
NZ (1) NZ507056A (el)
PE (1) PE20001089A1 (el)
PL (1) PL201688B1 (el)
PT (4) PT1059933E (el)
TR (1) TR200003455T2 (el)
TW (1) TW576747B (el)
UA (1) UA72205C2 (el)
WO (1) WO2000010596A1 (el)

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EP1222465A1 (en) * 1999-09-20 2002-07-17 Eli Lilly And Company Method for monitoring treatment with a parathyroid hormone
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
CA2472472A1 (en) * 2002-01-10 2003-07-24 Osteotrophin Llc Treatment of bone disorders with skeletal anabolic drugs
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
RU2006108557A (ru) * 2003-09-19 2007-09-27 Пфайзер Продактс Инк. (Us) Фармацевтические композиции, включающие в себя сочетания производных 2-алкилиден-19-нор-витамина d и паратиреоидного гормона, и способы (лечения)
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
JP2007537274A (ja) * 2004-05-10 2007-12-20 ナステック ファーマスーティカル カンパニー インク. 副甲状腺ホルモンの粘膜送達を増強するための組成物及び方法
US20060189533A1 (en) * 2004-05-10 2006-08-24 Nastech Pharmaceutical Company Inc. Stable pharmaceutical dosage forms of teriparatide
BRPI0509788A (pt) 2004-05-13 2007-10-23 Alza Corp aparato e método para liberação transdérmica de agentes de hormÈnio paratireóides
US7648965B2 (en) 2004-05-14 2010-01-19 Unigene Laboratories Inc. Method for fostering bone formation and preservation
US20060069021A1 (en) * 2004-08-13 2006-03-30 Nastech Pharmaceutical Company Inc. Compositions and methods for intranasal administration of inactive analogs of PTH or inactivated preparations of PTH or PTH analogs
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
WO2006073711A2 (en) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
CA2608016A1 (en) * 2005-05-11 2006-11-23 Unigene Laboratories, Inc. Improving bone formation and preservation by surgically inducing an increase in osteoblast activity coupled with the effect of administering pthrp or cgrp
US20070173447A1 (en) * 2005-10-25 2007-07-26 Nastech Pharmaceutical Company Inc. Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
AU2006315132A1 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US20080051332A1 (en) * 2005-11-18 2008-02-28 Nastech Pharmaceutical Company Inc. Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20080119408A1 (en) * 2006-07-07 2008-05-22 Nastech Pharmaceutical Company Inc. Pth formulations for intranasal delivery
EP1961765A1 (en) * 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
JP2010523243A (ja) 2007-04-13 2010-07-15 クロス・バイオサージェリー・アクチェンゲゼルシャフト 高分子組織シーラント
US20110137243A1 (en) * 2007-09-06 2011-06-09 Abbott Cardiovascular Systems Inc. Coating On A Balloon Device
US9457056B2 (en) * 2007-12-04 2016-10-04 Ben-Gurion University Of The Negev Research And Development Authority Peptides comprising alternating hydrophobic and anionic amino acids for treatment of osteoporosis
JP2012512812A (ja) 2007-12-28 2012-06-07 クロス・バイオサージェリー・アクチェンゲゼルシャフト フィブリンフォームに組込まれたpdgf融合タンパク質
CN102470164B (zh) 2009-09-09 2014-04-09 旭化成制药株式会社 以每周给药1次每次为100单位~200单位的pth为特征的、含有pth的骨质疏松症治疗/预防剂
EP2509996A1 (en) 2009-12-07 2012-10-17 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
WO2012111852A1 (ja) * 2011-02-17 2012-08-23 帝人ファーマ株式会社 椎体骨折治療剤及びその評価方法
ES2882852T3 (es) 2011-03-16 2021-12-02 Kuros Biosurgery Ag Formulación farmacéutica para la utilización en la fusión espinal
CN108195965B (zh) 2011-06-07 2021-02-23 旭化成制药株式会社 含pth肽冷冻干燥制剂的检査方法及包含该含pth肽冷冻干燥制剂的医药品的制造方法
US9700485B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
CA3013443C (en) * 2016-02-01 2021-06-15 Eli Lilly And Company Parathyroid hormone - anti-rankl antibody fusion compounds
JP2020506926A (ja) * 2017-02-01 2020-03-05 ザ・ジョンズ・ホプキンス・ユニバーシティ 副甲状腺ホルモンと変性椎間板疾患の再生
CA3075977A1 (en) * 2017-09-22 2019-03-28 Asahi Kasei Pharma Corporation Teriparatide-containing liquid pharmaceutical composition having excellent stability
CN111447943A (zh) 2018-10-29 2020-07-24 旭化成制药株式会社 以按每周2次的频率给予特立帕肽或其盐为特征的骨质疏松症的预防或治疗方法
WO2021030222A1 (en) 2019-08-09 2021-02-18 Flagship Pioneering Innovations Vi, Llc Modulators of parathyroid hormone receptor (pthr1)
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DZ2873A1 (fr) 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
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Also Published As

Publication number Publication date
CA2325371C (en) 2004-08-17
ES2549551T3 (es) 2017-11-27
ES2549551T1 (es) 2015-10-29
HU230697B1 (hu) 2017-09-28
PT1059933E (pt) 2003-06-30
PE20001089A1 (es) 2000-11-04
ID29039A (id) 2001-07-26
EP2266598A1 (en) 2010-12-29
DK2266598T3 (en) 2017-05-15
CA2325371A1 (en) 2000-03-02
HUP0101594A3 (en) 2002-01-28
CY1113343T1 (el) 2016-06-22
EP2266598B1 (en) 2017-02-22
CO5130020A1 (es) 2002-02-27
NO20005947L (no) 2000-11-24
CN1205997C (zh) 2005-06-15
DK1769804T3 (da) 2012-10-15
PL201688B1 (pl) 2009-04-30
DZ2873A1 (fr) 2003-12-15
JP2011021035A (ja) 2011-02-03
JP6177718B2 (ja) 2017-08-09
WO2000010596A1 (en) 2000-03-02
EA200001015A1 (ru) 2001-02-26
CZ301017B6 (cs) 2009-10-14
CN1308545A (zh) 2001-08-15
NO20072983L (no) 2000-11-24
KR100454207B1 (ko) 2004-10-26
HK1102496A1 (en) 2007-11-23
UA72205C2 (uk) 2005-02-15
HUP0101594A2 (hu) 2001-11-28
ES2190244T3 (es) 2003-07-16
DE15152726T1 (de) 2015-12-10
JP2015028065A (ja) 2015-02-12
DK2907522T3 (en) 2017-10-23
AU746277B2 (en) 2002-04-18
JP2002523375A (ja) 2002-07-30
AU5575099A (en) 2000-03-14
HRP20000755A2 (en) 2001-02-28
JP2014139220A (ja) 2014-07-31
IL138829A0 (en) 2001-10-31
DE69904918D1 (de) 2003-02-20
AR033639A1 (es) 2004-01-07
NO20005947D0 (no) 2000-11-24
US7163684B2 (en) 2007-01-16
HU1200430D0 (hu) 2001-11-28
NO323984B1 (no) 2007-07-30
KR20010072763A (ko) 2001-07-31
PT1769804E (pt) 2012-11-13
DE69904918T2 (de) 2003-11-13
PL343595A1 (en) 2001-08-27
HK1212602A1 (zh) 2016-06-17
EA003362B1 (ru) 2003-04-24
PT2266598T (pt) 2017-05-02
EP1059933A1 (en) 2000-12-20
CZ20004134A3 (cs) 2001-08-15
DK2907522T1 (da) 2015-10-19
NZ507056A (en) 2003-10-31
JP2017190332A (ja) 2017-10-19
TR200003455T2 (tr) 2001-06-21
EP2907522B1 (en) 2017-08-02
US6977077B1 (en) 2005-12-20
EP1059933B1 (en) 2003-01-15
BR9909445A (pt) 2000-12-12
PT2907522T (pt) 2017-10-23
ES2393200T3 (es) 2012-12-19
EP2907522A1 (en) 2015-08-19
ATE231000T1 (de) 2003-02-15
HK1030545A1 (en) 2001-05-11
TW576747B (en) 2004-02-21
US20050197294A1 (en) 2005-09-08
CY1119552T1 (el) 2018-03-07
IL138829A (en) 2011-01-31
MY129227A (en) 2007-03-30
ES2621653T3 (es) 2017-07-04

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