DK1032571T3 - Cykliske peridinylaminomethyl-triflourmethyl-ether-forbindelser som substans P-antagonister - Google Patents

Cykliske peridinylaminomethyl-triflourmethyl-ether-forbindelser som substans P-antagonister

Info

Publication number
DK1032571T3
DK1032571T3 DK98947726T DK98947726T DK1032571T3 DK 1032571 T3 DK1032571 T3 DK 1032571T3 DK 98947726 T DK98947726 T DK 98947726T DK 98947726 T DK98947726 T DK 98947726T DK 1032571 T3 DK1032571 T3 DK 1032571T3
Authority
DK
Denmark
Prior art keywords
peridinylaminomethyl
triflourmethyl
antagonists
cyclic
substance
Prior art date
Application number
DK98947726T
Other languages
English (en)
Inventor
Kunio Satake
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK1032571T3 publication Critical patent/DK1032571T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76Benzo[c]pyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98947726T 1997-11-19 1998-10-26 Cykliske peridinylaminomethyl-triflourmethyl-ether-forbindelser som substans P-antagonister DK1032571T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9701466 1997-11-19
PCT/IB1998/001704 WO1999025714A1 (en) 1997-11-19 1998-10-26 Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance p antagonists

Publications (1)

Publication Number Publication Date
DK1032571T3 true DK1032571T3 (da) 2002-07-15

Family

ID=11004634

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98947726T DK1032571T3 (da) 1997-11-19 1998-10-26 Cykliske peridinylaminomethyl-triflourmethyl-ether-forbindelser som substans P-antagonister

Country Status (40)

Country Link
US (2) US20030208079A1 (da)
EP (1) EP1032571B1 (da)
JP (2) JP3394239B2 (da)
KR (1) KR100366902B1 (da)
CN (1) CN1173974C (da)
AP (1) AP909A (da)
AR (1) AR016422A1 (da)
AT (1) ATE219078T1 (da)
AU (1) AU734218B2 (da)
BG (1) BG63969B1 (da)
CA (1) CA2310627C (da)
CO (1) CO4771153A1 (da)
CZ (1) CZ297315B6 (da)
DE (1) DE69806045T2 (da)
DK (1) DK1032571T3 (da)
DZ (1) DZ2655A1 (da)
EA (1) EA002621B1 (da)
ES (1) ES2177058T3 (da)
HK (1) HK1033313A1 (da)
HR (1) HRP20000313B1 (da)
HU (1) HUP0101112A3 (da)
ID (1) ID24240A (da)
IL (1) IL135631A0 (da)
IS (1) IS2202B (da)
MA (1) MA26567A1 (da)
MY (1) MY120558A (da)
NO (2) NO20002544L (da)
NZ (1) NZ503912A (da)
OA (1) OA11380A (da)
PA (1) PA8463001A1 (da)
PE (1) PE20000021A1 (da)
PL (1) PL193484B1 (da)
PT (1) PT1032571E (da)
RS (1) RS49792B (da)
SK (1) SK283460B6 (da)
TN (1) TNSN98210A1 (da)
TR (1) TR200001463T2 (da)
TW (1) TW426667B (da)
UA (1) UA59417C2 (da)
WO (1) WO1999025714A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9812662D0 (en) * 1998-06-11 1998-08-12 Merck Sharp & Dohme Therapeutic use
GB9812617D0 (en) * 1998-06-11 1998-08-12 Merck Sharp & Dohme Therapeutic use
EA200101050A1 (ru) * 1999-05-06 2002-04-25 Пфайзер Продактс Инк. Замещенные бензолактамные соединения
RS49964B (sr) 1999-05-17 2008-09-29 Pfizer Products Inc., Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli
ATE234832T1 (de) * 1999-05-21 2003-04-15 Pfizer Prod Inc 1-trifluorotmethyl-4-hydroxy-7-piperidinyl- aminomethylchroman-derivate
AU7557000A (en) * 1999-10-07 2001-05-10 Hisamitsu Pharmaceutical Co. Inc. Piperidine derivatives
PT1095939E (pt) * 1999-10-18 2004-04-30 Pfizer Prod Inc Processo para a preparacao de eteres ciclicos de compostos com piperidinilaminometilo
JP2001172178A (ja) * 1999-10-25 2001-06-26 Pfizer Prod Inc 偏頭痛治療用のnk−1レセプターアンタゴニスト及びエレトリプタン
IL142810A0 (en) * 2000-05-03 2002-03-10 Pfizer Prod Inc Pharmaceutical uses for fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
EP1192952A3 (en) * 2000-09-28 2003-03-26 Pfizer Products Inc. Combination, for treating depression and anxiety, containing an NK-3 receptor antagonist and a CNS penetrant NK-1 receptor antagonist
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
DK1288208T3 (da) 2001-08-30 2006-10-16 Pfizer Prod Inc Fremgangsmåde til fremstilling af 2-(4-alkyl-1-piperazinyl)-benzaldehyd- og -benzylidenforbindelser ved nucleofil aromatisk substituering af 2-flourbenzaldehyd med 4-alkyl-1-peperazin i vand som oplösningsmiddel
US20040001895A1 (en) * 2002-06-17 2004-01-01 Pfizer Inc. Combination treatment for depression and anxiety
AU2003262773A1 (en) * 2002-08-27 2004-03-19 David T. Harris Amelioration of effects of cigarette smoke
US6911544B2 (en) * 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
US7122700B2 (en) 2004-07-30 2006-10-17 Xerox Corporation Arylamine processes
DE102008000891A1 (de) 2008-03-31 2009-10-01 Robert Bosch Gmbh Schutzsystem für Werkzeugmaschinen
NO2729147T3 (da) 2011-07-04 2018-02-03
CN111918647A (zh) 2018-02-26 2020-11-10 圣拉斐尔医院有限公司 用于治疗眼痛的nk-1拮抗剂
US20230134843A1 (en) 2020-03-11 2023-05-04 Ospedale San Raffaele S.R.L. Treatment of stem cell deficiency

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9317987D0 (en) * 1993-08-26 1993-10-13 Glaxo Group Ltd Chemical compounds
US5886011A (en) * 1995-03-27 1999-03-23 Hisamitsu Pharmaceutical Co., Inc. Piperidine derivatives as substance P antagonists
TW475930B (en) * 1995-04-24 2002-02-11 Novartis Ag Novel compound, its use and pharmaceutical composition comprising it
DE69612003T2 (de) * 1995-07-07 2001-06-21 Pfizer Substituierte benzolaktamverbindungen als substanz-p-antagonisten
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
US6329396B1 (en) * 1996-06-10 2001-12-11 Pfizer Inc. Substituted benzylaminopiperidine compounds
ATE234832T1 (de) * 1999-05-21 2003-04-15 Pfizer Prod Inc 1-trifluorotmethyl-4-hydroxy-7-piperidinyl- aminomethylchroman-derivate
PT1095939E (pt) * 1999-10-18 2004-04-30 Pfizer Prod Inc Processo para a preparacao de eteres ciclicos de compostos com piperidinilaminometilo

Also Published As

Publication number Publication date
PL193484B1 (pl) 2007-02-28
DZ2655A1 (fr) 2003-03-22
ID24240A (id) 2000-07-13
AU9454998A (en) 1999-06-07
JP2003040777A (ja) 2003-02-13
EA200000432A1 (ru) 2000-12-25
EA002621B1 (ru) 2002-06-27
NZ503912A (en) 2002-09-27
HK1033313A1 (en) 2001-08-24
PL340642A1 (en) 2001-02-12
CN1279681A (zh) 2001-01-10
MA26567A1 (fr) 2004-12-20
TR200001463T2 (tr) 2000-12-21
HUP0101112A2 (hu) 2002-05-29
HRP20000313B1 (en) 2002-04-30
IL135631A0 (en) 2001-05-20
CN1173974C (zh) 2004-11-03
SK283460B6 (sk) 2003-08-05
IS2202B (is) 2007-02-15
NO20002544D0 (no) 2000-05-18
SK7232000A3 (en) 2001-09-11
AP9801402A0 (en) 1998-12-31
CZ297315B6 (cs) 2006-11-15
ES2177058T3 (es) 2002-12-01
AR016422A1 (es) 2001-07-04
RS49792B (sr) 2008-06-05
ATE219078T1 (de) 2002-06-15
HUP0101112A3 (en) 2002-06-28
CO4771153A1 (es) 1999-04-30
CA2310627A1 (en) 1999-05-27
NO20002544L (no) 2000-07-17
TW426667B (en) 2001-03-21
UA59417C2 (uk) 2003-09-15
AU734218B2 (en) 2001-06-07
JP2001523680A (ja) 2001-11-27
CA2310627C (en) 2005-08-09
PE20000021A1 (es) 2000-02-25
US20050171354A1 (en) 2005-08-04
CZ20001834A3 (cs) 2001-07-11
NO20042879L (no) 2000-07-17
DE69806045D1 (en) 2002-07-18
WO1999025714A1 (en) 1999-05-27
US20030208079A1 (en) 2003-11-06
KR100366902B1 (ko) 2003-01-09
PT1032571E (pt) 2002-09-30
EP1032571B1 (en) 2002-06-12
HRP20000313A2 (en) 2000-12-31
TNSN98210A1 (fr) 2005-03-15
MY120558A (en) 2005-11-30
EP1032571A1 (en) 2000-09-06
PA8463001A1 (es) 2000-09-29
OA11380A (en) 2004-01-27
JP3394239B2 (ja) 2003-04-07
BG63969B1 (bg) 2003-08-29
AP909A (en) 2000-12-04
DE69806045T2 (de) 2002-11-14
BG104437A (en) 2001-02-28
YU29400A (sh) 2003-02-28
IS5470A (is) 2000-04-26

Similar Documents

Publication Publication Date Title
DK1032571T3 (da) Cykliske peridinylaminomethyl-triflourmethyl-ether-forbindelser som substans P-antagonister
DE69905038T2 (de) Cyclische boroprolinverbindungen
DK1218359T3 (da) Piperazinforbindelser som tachykininantagonister
NO20003930L (no) Sammensetninger som inneholder organiske forbindelser
EE200000044A (et) Uued ühendid
NO20012948L (no) Hydroksydifenylureasulfonamider som IL-8 reseptor antagonister
NO971137D0 (no) Dimetyl-(3-aryl-but-3-enyl)-aminforbindelse som farmasöytiske forbindelser
FI4209U1 (fi) Uusia yhdisteitä
DK0975623T3 (da) Indazolamidforbindelser som sertoninerge midler
DK1027342T3 (da) Cyclopentenderivater som motilinreceptorantagonister
DK0964863T3 (da) Oxazolidinoner som 5-HT2A-antagonister
NO20006227L (no) Tetrahydroquiolinderivater som glycin antagonister
BR9804301B1 (pt) compostos espirocÍclicos.
NO995782D0 (no) Kvarternaere ammoniumforbindelser som tachykinin-antagonister
DK1261588T3 (da) Imidazolforbindelser som alfa2-adrenoceptorantagonister
NO20002575D0 (no) Substituerte oksimer som neurokininantagonister
IL144466A0 (en) Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance p antagonists
SI1032571T1 (en) Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance p antagonists
ZA9810544B (en) Piperidinylaminomethyl Trifluoromethyl cyclic ether compounds as substance P antagonists.
FI974550A0 (fi) Styrsystem foer en soekmaskin, som anvaends i samband med ett data- eller telekommunikationsnaet
DK0994876T3 (da) Kvaternære ammoniumforbindelser som tachykinin-antagonister
SE9803106D0 (sv) Novel formulation
SE9704839D0 (sv) New compounds
SE9704838D0 (sv) New compounds
SE9702746D0 (sv) New compounds