NO20012948L - Hydroksydifenylureasulfonamider som IL-8 reseptor antagonister - Google Patents
Hydroksydifenylureasulfonamider som IL-8 reseptor antagonisterInfo
- Publication number
- NO20012948L NO20012948L NO20012948A NO20012948A NO20012948L NO 20012948 L NO20012948 L NO 20012948L NO 20012948 A NO20012948 A NO 20012948A NO 20012948 A NO20012948 A NO 20012948A NO 20012948 L NO20012948 L NO 20012948L
- Authority
- NO
- Norway
- Prior art keywords
- hydroxydiphenylureasulfonamides
- receptor antagonists
- antagonists
- receptor
- Prior art date
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
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- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US11248198P | 1998-12-16 | 1998-12-16 | |
US13700399P | 1999-06-01 | 1999-06-01 | |
PCT/US1999/029940 WO2000035442A1 (en) | 1998-12-16 | 1999-12-15 | Hydroxy diphenyl urea sulfonamides as il-8 receptor antagonists |
Publications (2)
Publication Number | Publication Date |
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NO20012948D0 NO20012948D0 (no) | 2001-06-14 |
NO20012948L true NO20012948L (no) | 2001-06-15 |
Family
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Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20012948A NO20012948L (no) | 1998-12-16 | 2001-06-14 | Hydroksydifenylureasulfonamider som IL-8 reseptor antagonister |
Country Status (32)
Country | Link |
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US (2) | US6500863B1 (no) |
EP (1) | EP1161232B1 (no) |
JP (1) | JP2002532419A (no) |
KR (1) | KR20010101243A (no) |
CN (1) | CN1334726A (no) |
AR (1) | AR029605A1 (no) |
AT (1) | ATE262328T1 (no) |
AU (1) | AU748799B2 (no) |
BG (1) | BG105661A (no) |
BR (1) | BR9916159A (no) |
CA (1) | CA2355890A1 (no) |
CO (1) | CO4990929A1 (no) |
CZ (1) | CZ20012150A3 (no) |
DE (1) | DE69915888T2 (no) |
DK (1) | DK1161232T3 (no) |
DZ (1) | DZ2964A1 (no) |
EA (1) | EA005210B1 (no) |
ES (1) | ES2217871T3 (no) |
HK (1) | HK1043535B (no) |
HU (1) | HUP0104686A3 (no) |
IL (1) | IL143507A0 (no) |
MA (1) | MA25366A1 (no) |
NO (1) | NO20012948L (no) |
NZ (1) | NZ511993A (no) |
OA (1) | OA11731A (no) |
PE (1) | PE20001323A1 (no) |
PL (1) | PL348179A1 (no) |
PT (1) | PT1161232E (no) |
SK (1) | SK8222001A3 (no) |
TR (1) | TR200101772T2 (no) |
UY (1) | UY25842A1 (no) |
WO (1) | WO2000035442A1 (no) |
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ATE556713T1 (de) | 1999-01-13 | 2012-05-15 | Bayer Healthcare Llc | Omega-carboxyarylsubstituierte-diphenyl- harnstoffe als p38-kinasehemmer |
EP1140840B1 (en) * | 1999-01-13 | 2006-03-22 | Bayer Pharmaceuticals Corp. | -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
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AU2001243351A1 (en) * | 2000-03-01 | 2001-09-12 | Smith Kline Beecham Corporation | Il-8 receptor antagonists |
US20030050298A1 (en) * | 2000-03-10 | 2003-03-13 | Palovich Michael R | Il-8 receptor antagonists |
AR030273A1 (es) * | 2000-03-10 | 2003-08-20 | Smithkline Beecham Corp | Compuestos de hidroxifenil urea sustituidos con sulfonamidas, composiciones farmaceuticas que los comprenden, y uso de los mismos en la fabricacion de medicamentos para tratar una enfermedad mediada por una quimioquina |
AR030689A1 (es) * | 2000-03-14 | 2003-09-03 | Smithkline Beecham Corp | Compuestos de 3-aminosulfonil-2-hidroxifenil urea, composiciones farmaceuticas que los comprenden, y uso de dichos compuestos en la manufactura de medicamentos para tratar enfermedades mediadas por quimioquinas |
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UA82827C2 (en) * | 2000-12-18 | 2008-05-26 | Inhibitors against the production and release of inflammatory cytokines | |
WO2002057230A1 (en) * | 2001-01-16 | 2002-07-25 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
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US7557129B2 (en) | 2003-02-28 | 2009-07-07 | Bayer Healthcare Llc | Cyanopyridine derivatives useful in the treatment of cancer and other disorders |
JP4860474B2 (ja) | 2003-05-20 | 2012-01-25 | バイエル、ファーマシューテイカルズ、コーポレイション | Pdgfrによって仲介される病気のためのジアリール尿素 |
DK1663978T3 (da) | 2003-07-23 | 2008-04-07 | Bayer Pharmaceuticals Corp | Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser |
JP2008517054A (ja) * | 2004-10-20 | 2008-05-22 | スミスクライン・ビーチャム・コーポレイション | Il−8受容体アンタゴニスト |
TWI414517B (zh) * | 2006-04-21 | 2013-11-11 | Smithkline Beecham Corp | Il-8受體拮抗劑 |
EP2010180A4 (en) * | 2006-04-21 | 2010-10-13 | Glaxosmithkline Llc | IL-8 RECEPTOR ANTAGONISTS |
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TW200817006A (en) * | 2006-06-23 | 2008-04-16 | Smithkline Beecham Corp | IL-8 receptor antagonist |
EP2110019A1 (de) | 2008-04-19 | 2009-10-21 | Bayer CropScience AG | Herbizide Verbindungen auf Basis von N-Azinyl-N'-phenylsulfonylharnstoffen |
CN102985557B (zh) | 2009-03-13 | 2018-06-15 | 安吉奥斯医药品有限公司 | 用于细胞增殖相关病症的方法和组合物 |
PL2448582T3 (pl) | 2009-06-29 | 2017-09-29 | Agios Pharmaceuticals, Inc. | Pochodne chinolino-8-sulfonamidowe mające działanie przeciwnowotworowe |
EP2491145B1 (en) | 2009-10-21 | 2016-03-09 | Agios Pharmaceuticals, Inc. | Methods and compositions for cell-proliferation-related disorders |
WO2011050211A2 (en) | 2009-10-21 | 2011-04-28 | Agios Pharmaceuticals, Inc. | Methods and compositions for cell-proliferation-related disorders |
WO2011047788A1 (en) * | 2009-10-21 | 2011-04-28 | Bayer Schering Pharma Aktiengesellschaft | Substituted benzosulphonamides |
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CN103764147B (zh) | 2011-05-03 | 2018-05-22 | 安吉奥斯医药品有限公司 | 用于治疗的丙酮酸激酶活化剂 |
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CN108912066B (zh) | 2012-01-06 | 2022-06-24 | 安吉奥斯医药品有限公司 | 治疗活性化合物及其使用方法 |
US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
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KR102302091B1 (ko) | 2013-07-11 | 2021-09-16 | 아지오스 파마슈티컬스 아이엔씨. | 암 치료용의 idh2 돌연변이체 억제제로서의 n,6-비스(아릴 또는 헤테로아릴)-1,3,5-트리아진-2,4-디아민 화합물 |
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EP3019480B1 (en) | 2013-07-11 | 2020-05-06 | Agios Pharmaceuticals, Inc. | 2,4- or 4,6-diaminopyrimidine compounds as idh2 mutants inhibitors for the treatment of cancer |
US20150031627A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
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US3972886A (en) * | 1972-07-13 | 1976-08-03 | Leo Pharmaceutical Products Ltd. | Certain 4-phenoxy-3-heteroarylmethyl or ethyl sulfamyl benzoic acid derivatives |
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US6218539B1 (en) * | 1996-06-27 | 2001-04-17 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
DE69826695T2 (de) * | 1997-05-23 | 2006-02-02 | Bayer Pharmaceuticals Corp., West Haven | Arylharnstoffderivate zur behandlung von inflammatorischen oder immunomodulatorischen erkrankungen |
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- 1999-12-12 DZ DZ990264A patent/DZ2964A1/xx active
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- 1999-12-14 PE PE1999001243A patent/PE20001323A1/es not_active Application Discontinuation
- 1999-12-14 AR ARP990106373A patent/AR029605A1/es not_active Application Discontinuation
- 1999-12-15 US US09/868,165 patent/US6500863B1/en not_active Expired - Fee Related
- 1999-12-15 DE DE1999615888 patent/DE69915888T2/de not_active Expired - Lifetime
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- 1999-12-15 BR BR9916159-1A patent/BR9916159A/pt not_active IP Right Cessation
- 1999-12-15 CZ CZ20012150A patent/CZ20012150A3/cs unknown
- 1999-12-15 JP JP2000587762A patent/JP2002532419A/ja not_active Ceased
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- 1999-12-15 EA EA200100659A patent/EA005210B1/ru not_active IP Right Cessation
- 1999-12-15 KR KR1020017007504A patent/KR20010101243A/ko not_active Application Discontinuation
- 1999-12-15 PL PL99348179A patent/PL348179A1/xx not_active Application Discontinuation
- 1999-12-15 HU HU0104686A patent/HUP0104686A3/hu unknown
- 1999-12-15 CN CN99816125A patent/CN1334726A/zh active Pending
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- 1999-12-15 WO PCT/US1999/029940 patent/WO2000035442A1/en not_active Application Discontinuation
- 1999-12-15 OA OA1200100154A patent/OA11731A/en unknown
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- 1999-12-15 AU AU31237/00A patent/AU748799B2/en not_active Ceased
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