DK1021171T3 - Lægemiddelfremførelsessystem til forsinket, fuldstændig frigivelse gastrointestinalt - Google Patents

Lægemiddelfremførelsessystem til forsinket, fuldstændig frigivelse gastrointestinalt

Info

Publication number
DK1021171T3
DK1021171T3 DK98949742T DK98949742T DK1021171T3 DK 1021171 T3 DK1021171 T3 DK 1021171T3 DK 98949742 T DK98949742 T DK 98949742T DK 98949742 T DK98949742 T DK 98949742T DK 1021171 T3 DK1021171 T3 DK 1021171T3
Authority
DK
Denmark
Prior art keywords
core
drug
coating
insoluble
delivery system
Prior art date
Application number
DK98949742T
Other languages
Danish (da)
English (en)
Inventor
E Itzhak Lerner
Moshe Flashner
Adel Penhasi
Original Assignee
Dexcel Pharma Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dexcel Pharma Technologies Ltd filed Critical Dexcel Pharma Technologies Ltd
Application granted granted Critical
Publication of DK1021171T3 publication Critical patent/DK1021171T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98949742T 1997-10-09 1998-10-01 Lægemiddelfremførelsessystem til forsinket, fuldstændig frigivelse gastrointestinalt DK1021171T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94823597A 1997-10-09 1997-10-09
US16320298A 1998-09-30 1998-09-30
PCT/US1998/020779 WO1999018938A1 (en) 1997-10-09 1998-10-01 Delayed total release gastrointestinal drug delivery system

Publications (1)

Publication Number Publication Date
DK1021171T3 true DK1021171T3 (da) 2003-08-25

Family

ID=26859435

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98949742T DK1021171T3 (da) 1997-10-09 1998-10-01 Lægemiddelfremførelsessystem til forsinket, fuldstændig frigivelse gastrointestinalt

Country Status (20)

Country Link
EP (1) EP1021171B1 (pl)
JP (1) JP2001519379A (pl)
KR (1) KR20010031034A (pl)
CN (1) CN100548279C (pl)
AT (1) ATE238774T1 (pl)
AU (1) AU740757B2 (pl)
BR (1) BR9815240A (pl)
CA (1) CA2305762C (pl)
CZ (1) CZ301028B6 (pl)
DE (1) DE69814122T2 (pl)
DK (1) DK1021171T3 (pl)
ES (1) ES2198756T3 (pl)
HU (1) HUP0004945A3 (pl)
IL (1) IL135502A (pl)
NO (1) NO20001829L (pl)
NZ (1) NZ503820A (pl)
PL (1) PL203733B1 (pl)
PT (1) PT1021171E (pl)
TR (1) TR200000944T2 (pl)
WO (1) WO1999018938A1 (pl)

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CN1285333C (zh) * 2000-06-07 2006-11-22 张昊 结肠定位释放的口服制剂及其制备方法
EP1738751B1 (en) 2001-01-12 2011-05-11 Sun Pharma Advanced Research Company Ltd Spaced drug delivery system
ATE526951T1 (de) * 2001-04-10 2011-10-15 Sun Pharma Advanced Res Co Ltd Zubereitung zur getakteten freisetzung
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PL1631251T3 (pl) 2003-04-24 2011-12-30 Jagotec Ag Tabletka o opóźnionym uwalnianiu i o określonej geometrii
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
KR100645019B1 (ko) * 2004-06-03 2006-11-14 주식회사 리젠 바이오텍 비수용성 무기화합물이 포집되어 있는 고분자 비드, 이의제조방법 및 용도
BRPI0606395A2 (pt) * 2005-01-05 2009-06-23 Univ Texas conjugados para ambas imagem e radioquimioterapia: composição, fabricação e aplicações
US20100135907A1 (en) * 2005-07-22 2010-06-03 Cranley Paul E Oral Drug Compliance Monitoring Using Sound Detection
CN101287443B (zh) 2005-07-29 2013-05-29 斯蒂茨廷格罗宁根药物研究中心 pH控制的脉冲释放系统、其制备方法和用途
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
JP5372525B2 (ja) 2006-03-03 2013-12-18 エフ エム シー コーポレーション カプセルの製造方法および該製造方法により製造されるカプセル
JP2007284483A (ja) * 2006-04-13 2007-11-01 Daito Kasei Kogyo Kk 吸湿性顔料およびそれを含有する化粧料
US20070270443A1 (en) * 2006-05-19 2007-11-22 Gregory Went Methods and compositions for the treatment of viral infections
MY149863A (en) 2006-08-03 2013-10-31 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
WO2008044236A2 (en) * 2006-10-10 2008-04-17 Dexcel Pharma Technologies Ltd. Improved release of statins in the intestine
US20090143343A1 (en) 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
JP2011503073A (ja) 2007-11-13 2011-01-27 メリテイジ ファーマ，インク． コルチコステロイド組成物
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
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US10391059B2 (en) 2009-11-11 2019-08-27 Rapamycin Holdings, Inc. Oral rapamycin nanoparticle preparations and use
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JP6504548B2 (ja) 2014-02-21 2019-04-24 プリンシピア バイオファーマ インコーポレイテッド Ｂｔｋ阻害剤の塩および固体形態
EP3131546B1 (en) 2014-04-16 2022-02-16 Rapamycin Holdings, Inc. Oral rapamycin preparation for use in treating feline chronic gingivo- stomatitis (fcgs)
US10485797B2 (en) 2014-12-18 2019-11-26 Principia Biopharma Inc. Treatment of pemphigus
CA2971109A1 (en) * 2014-12-24 2016-06-30 Principia Biopharma Inc. Site specific dosing of a btk inhibitor
MA42242A (fr) 2015-06-24 2018-05-02 Principia Biopharma Inc Inhibiteurs de la tyrosine kinase
GB201511284D0 (en) * 2015-06-26 2015-08-12 Univ Witwatersrand Jhb An oral pharmaceutical dosage form for the delivery of a peptide and/or protein
CN105434403A (zh) * 2015-12-30 2016-03-30 成都医学院 一种溴吡斯的明包衣缓释微丸及其制备方法
BR112018077503A2 (pt) 2016-06-29 2019-04-09 Principia Biopharma Inc. formulações de liberação modificada de 2-[3-[4-amino-3-(2-fluoro-4- fenoxi-fenil)pirazolo [3,4-d]pirimidin-1-il]piperidino-1- carbonil]-4-metil-4-[4-(oxetan-3-il)piperazin-1-il] pent-2-enenitrila
JP6780412B2 (ja) * 2016-09-28 2020-11-04 ライオン株式会社 コーティング組成物ならびにコーティング製剤及びその製造方法
CN116075294A (zh) * 2020-06-11 2023-05-05 詹森生物科技公司 用于局部药物递送的自包埋颗粒的受控释放
CN112544964B (zh) * 2020-12-28 2024-03-19 苏州大学 一种可服用胶囊及其制备方法与应用
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Also Published As

Publication number Publication date
EP1021171B1 (en) 2003-05-02
TR200000944T2 (tr) 2000-11-21
NO20001829L (no) 2000-06-07
EP1021171A1 (en) 2000-07-26
CN100548279C (zh) 2009-10-14
HUP0004945A2 (hu) 2001-08-28
CZ301028B6 (cs) 2009-10-14
AU9600198A (en) 1999-05-03
CZ20001256A3 (cs) 2000-10-11
IL135502A0 (en) 2001-05-20
HUP0004945A3 (en) 2005-03-29
PT1021171E (pt) 2003-10-31
NO20001829D0 (no) 2000-04-07
PL203733B1 (pl) 2009-11-30
PL339861A1 (en) 2001-01-15
ES2198756T3 (es) 2004-02-01
KR20010031034A (ko) 2001-04-16
IL135502A (en) 2006-07-05
JP2001519379A (ja) 2001-10-23
ATE238774T1 (de) 2003-05-15
NZ503820A (en) 2004-02-27
CA2305762C (en) 2006-09-26
AU740757B2 (en) 2001-11-15
CN1274280A (zh) 2000-11-22
DE69814122T2 (de) 2004-03-18
DE69814122D1 (de) 2003-06-05
WO1999018938A1 (en) 1999-04-22
BR9815240A (pt) 2001-10-30
CA2305762A1 (en) 1999-04-22

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