DK1002794T3 - 4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer - Google Patents

4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer

Info

Publication number
DK1002794T3
DK1002794T3 DK99500208T DK99500208T DK1002794T3 DK 1002794 T3 DK1002794 T3 DK 1002794T3 DK 99500208 T DK99500208 T DK 99500208T DK 99500208 T DK99500208 T DK 99500208T DK 1002794 T3 DK1002794 T3 DK 1002794T3
Authority
DK
Denmark
Prior art keywords
serotonin
aryloxy
aryl
reuptake inhibitors
norepinephrine reuptake
Prior art date
Application number
DK99500208T
Other languages
Danish (da)
English (en)
Inventor
Venero Aurelio Orjales
Avello Antonio Toledo
Duran Carmen Pumar
Original Assignee
Faes Fabrica Espanola De Produ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Faes Fabrica Espanola De Produ filed Critical Faes Fabrica Espanola De Produ
Application granted granted Critical
Publication of DK1002794T3 publication Critical patent/DK1002794T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99500208T 1998-11-18 1999-11-10 4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer DK1002794T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009802420A ES2157148B1 (es) 1998-11-18 1998-11-18 Nuevas piperidinas 4-sustituidas.

Publications (1)

Publication Number Publication Date
DK1002794T3 true DK1002794T3 (da) 2009-04-14

Family

ID=8305832

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99500208T DK1002794T3 (da) 1998-11-18 1999-11-10 4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer

Country Status (21)

Country Link
EP (1) EP1002794B1 (no)
JP (1) JP4667552B2 (no)
KR (1) KR100646675B1 (no)
AR (1) AR028805A1 (no)
AT (1) ATE422199T1 (no)
AU (1) AU757177B2 (no)
BR (1) BR9905634B1 (no)
CA (1) CA2288533C (no)
CY (1) CY1108955T1 (no)
CZ (1) CZ296053B6 (no)
DE (1) DE69940378D1 (no)
DK (1) DK1002794T3 (no)
ES (2) ES2157148B1 (no)
HR (1) HRP990354B1 (no)
HU (1) HU227558B1 (no)
IL (1) IL132862A0 (no)
NO (1) NO314401B1 (no)
PL (1) PL196329B1 (no)
PT (1) PT1002794E (no)
RU (1) RU2232753C2 (no)
TR (1) TR199902839A2 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1513510A1 (en) * 2002-05-30 2005-03-16 Head Explorer A/S The use of milnacipran for the treatment of tension-type headache
UA77536C2 (en) * 2002-07-03 2006-12-15 Lundbeck & Co As H Secondary aminoaniline piperidines as mch1 antagonists and their use
WO2005092885A1 (en) * 2004-02-27 2005-10-06 Eli Lilly And Company 4-amino-piperidine derivatives as monoamine uptake inhibitors
CN1968932A (zh) 2004-06-18 2007-05-23 惠氏公司 制备6－烷基－5－芳基磺酰基－二氢菲啶的方法
EP1854785A1 (en) * 2006-05-12 2007-11-14 Faes Farma, S.A. 4-[(3-fluorophenoxy)phenylmethyl]piperidine methanesulfonate: uses, process of synthesis and pharmaceutical compositions
CN101506164A (zh) * 2006-08-23 2009-08-12 辉瑞产品公司 哌啶衍生物
AU2009313951B2 (en) * 2008-11-14 2015-03-12 Theravance Biopharma R&D Ip, Llc 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds
WO2010120910A1 (en) * 2009-04-15 2010-10-21 Theravance, Inc. 3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds
US20130131079A1 (en) 2010-05-24 2013-05-23 Faes Farma, S.A. Flufenoxine derivatives for the treatment and prevention of amyloid pathologies
EP2390248A1 (en) 2010-05-24 2011-11-30 Faes Farma, S.A. Flufenoxine derivatives for the treatment and prevention of amiloyd pathologies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1203149A (en) * 1968-06-10 1970-08-26 Ici Ltd Piperidine derivatives
JPH0615529B2 (ja) * 1985-04-01 1994-03-02 エーザイ株式会社 新規ピペリジン誘導体
JPH0840999A (ja) * 1994-08-04 1996-02-13 Yamanouchi Pharmaceut Co Ltd フルオロインダン誘導体
CO5150201A1 (es) * 1998-09-07 2002-04-29 Hoffmann La Roche Derivados de piperidina

Also Published As

Publication number Publication date
HRP990354A2 (en) 2000-06-30
HRP990354B1 (en) 2008-11-30
HUP9904086A2 (hu) 2000-11-28
AR028805A1 (es) 2003-05-28
JP2000154176A (ja) 2000-06-06
HU9904086D0 (en) 2000-01-28
JP4667552B2 (ja) 2011-04-13
TR199902839A3 (tr) 2000-09-21
DE69940378D1 (de) 2009-03-19
RU2232753C2 (ru) 2004-07-20
HUP9904086A3 (en) 2001-11-28
CA2288533C (en) 2009-01-06
ES2157148A1 (es) 2001-08-01
KR20000035525A (ko) 2000-06-26
AU5936699A (en) 2000-05-25
NO995643L (no) 2000-05-19
NO314401B1 (no) 2003-03-17
EP1002794B1 (en) 2009-02-04
PL336607A1 (en) 2000-05-22
BR9905634B1 (pt) 2012-09-04
CZ296053B6 (cs) 2005-12-14
ATE422199T1 (de) 2009-02-15
PT1002794E (pt) 2009-03-25
CY1108955T1 (el) 2014-07-02
ES2157148B1 (es) 2002-03-01
EP1002794A1 (en) 2000-05-24
BR9905634A (pt) 2000-09-26
AU757177B2 (en) 2003-02-06
HU227558B1 (en) 2011-08-29
ES2323742T3 (es) 2009-07-23
CA2288533A1 (en) 2000-05-18
IL132862A0 (en) 2001-03-19
CZ399599A3 (cs) 2000-08-16
KR100646675B1 (ko) 2006-11-17
PL196329B1 (pl) 2007-12-31
NO995643D0 (no) 1999-11-17
TR199902839A2 (xx) 2000-09-21

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