DK0974356T3 - Tabletter omfattende en kombination af metformin og glibenclamid - Google Patents

Tabletter omfattende en kombination af metformin og glibenclamid

Info

Publication number
DK0974356T3
DK0974356T3 DK98401781T DK98401781T DK0974356T3 DK 0974356 T3 DK0974356 T3 DK 0974356T3 DK 98401781 T DK98401781 T DK 98401781T DK 98401781 T DK98401781 T DK 98401781T DK 0974356 T3 DK0974356 T3 DK 0974356T3
Authority
DK
Denmark
Prior art keywords
glibenclamide
metformin
tablets
combination
Prior art date
Application number
DK98401781T
Other languages
Danish (da)
English (en)
Inventor
Yves Bonhomme
Geoffrey Nicholson
Original Assignee
Merck Sante Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0974356(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sante Sas filed Critical Merck Sante Sas
Application granted granted Critical
Publication of DK0974356T3 publication Critical patent/DK0974356T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98401781T 1998-07-15 1998-07-15 Tabletter omfattende en kombination af metformin og glibenclamid DK0974356T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98401781A EP0974356B1 (en) 1998-07-15 1998-07-15 Tablets comprising a combination of metformin and glibenclamide

Publications (1)

Publication Number Publication Date
DK0974356T3 true DK0974356T3 (da) 2003-10-27

Family

ID=8235441

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98401781T DK0974356T3 (da) 1998-07-15 1998-07-15 Tabletter omfattende en kombination af metformin og glibenclamid

Country Status (27)

Country Link
US (2) US6303146B1 (enExample)
EP (4) EP0974356B1 (enExample)
JP (2) JP2002520371A (enExample)
KR (2) KR20040053177A (enExample)
CN (2) CN1486698A (enExample)
AP (1) AP1450A (enExample)
AR (2) AR013052A1 (enExample)
AT (1) ATE250418T1 (enExample)
AU (2) AU753604B2 (enExample)
BR (1) BR9906600A (enExample)
CA (1) CA2303537C (enExample)
DE (1) DE69818444T2 (enExample)
DK (1) DK0974356T3 (enExample)
DZ (1) DZ2846A1 (enExample)
ES (1) ES2206868T3 (enExample)
ID (1) ID25784A (enExample)
MA (1) MA24930A1 (enExample)
MY (1) MY129552A (enExample)
NZ (1) NZ503248A (enExample)
OA (1) OA11400A (enExample)
PT (1) PT974356E (enExample)
RU (2) RU2226396C2 (enExample)
SI (1) SI0974356T1 (enExample)
TW (2) TWI245632B (enExample)
UY (1) UY25611A1 (enExample)
WO (1) WO2000003742A2 (enExample)
ZA (1) ZA200001159B (enExample)

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FR2816841B1 (fr) * 2000-11-22 2004-02-06 Lipha Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
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FR2825023B1 (fr) * 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
US20050271737A1 (en) * 2001-06-07 2005-12-08 Chinea Vanessa I Application of a bioactive agent to a substrate
US8206753B2 (en) * 2001-06-20 2012-06-26 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
CN1270724C (zh) * 2001-07-30 2006-08-23 三菱制药株式会社 餐后高血糖改善剂
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
ITFI20010230A1 (it) * 2001-11-29 2003-05-29 Menarini Int Operations Lu Sa Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
US7183321B2 (en) * 2001-12-17 2007-02-27 Bristol-Myers Squibb Company Antidiabetic formulation and method
US9045438B2 (en) * 2002-01-25 2015-06-02 Silanes S.A. De C.V. Pharmaceutical composition containing glimepiride and metformin hydrochloride
ATE536173T1 (de) * 2002-02-21 2011-12-15 Biovail Lab Int Srl Formulierungen mit modifizierter freisetzung von mindestens einer form von tramadol
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
US20030219482A1 (en) * 2002-03-21 2003-11-27 Chaudhari Sunil Sudhakar Multiparticulate compositions for once-a-day administration
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
CA2480824A1 (fr) 2002-04-09 2003-10-16 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline
WO2003105809A1 (en) 2002-06-17 2003-12-24 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
US7445796B2 (en) * 2002-08-19 2008-11-04 L. Perrigo Company Pharmaceutically active particles of a monomodal particle size distribution and method
EP1562607A1 (en) * 2002-11-15 2005-08-17 Ranbaxy Laboratories, Ltd. Pharmaceutical dosage forms of biguanide-sulfonylurea combinations
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation
CN1780642A (zh) * 2003-04-15 2006-05-31 中外制药株式会社 糖尿病治疗剂
US20060121108A1 (en) * 2004-12-02 2006-06-08 Prasad C K System and method for producing a directly compressible, high-potency formulation of metformin hydrochloride
CN100341495C (zh) * 2004-12-29 2007-10-10 三九医药股份有限公司 格列本脲固体分散体、口服组合物及其制备方法
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
US8529537B2 (en) * 2005-08-05 2013-09-10 Kimberly-Clark Worldwide, Inc. Absorbent article with enclosures
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
EP2452683A3 (en) 2006-06-26 2012-08-22 Amgen Inc. Methods for treating atherosclerosis
WO2008062273A2 (en) * 2006-11-20 2008-05-29 Cadila Pharmaceuticals Limited Solid oral dosage form having antidiabetic drug combination
JO3272B1 (ar) 2007-07-19 2018-09-16 Takeda Pharmaceuticals Co مستحضر صلب يشمل ألوجليبتين وميتفورمين هيدروكلوريد
NZ597885A (en) 2007-07-26 2013-08-30 Amgen Inc Modified lecithin-cholesterol acyltransferase enzymes
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
WO2011135106A1 (es) * 2010-04-26 2011-11-03 Smart Pharma Solutions, S.L Granulado altamente dispersable para la preparación de formulaciones de sustancias activas de altas dosis y procedimiento de obtención del mismo
RU2451506C1 (ru) 2011-06-02 2012-05-27 Сергей Юрьевич Лешков Комбинация для лечения сахарного диабета и его осложнений
WO2013086443A1 (en) 2011-12-08 2013-06-13 Amgen Inc. Agonistic human lcat antigen binding proteins and their use in therapy
EP2790729A4 (en) * 2011-12-12 2015-08-12 Orbis Biosciences Inc PARTICULATE FORMULATIONS WITH DELAYED RELEASE
CN104127424A (zh) * 2014-07-30 2014-11-05 沈阳药科大学 格列本脲衍生物及其制备方法和应用
CN105030793A (zh) * 2015-08-25 2015-11-11 瑞阳制药有限公司 二甲双胍格列本脲胶囊及其制备方法
WO2019070109A1 (es) * 2017-10-03 2019-04-11 Infinite Clinical Research International, S.A. De C.V. Triconjugado para el tratamiento de diabetes mellitus
CN115315426B (zh) 2020-04-01 2023-12-12 杭州中美华东制药有限公司 Glp-1受体激动剂游离碱的药学上可接受的酸式盐及其制备方法
EP4130005A4 (en) 2020-04-01 2024-04-24 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. CRYSTALLINE FORM A OF A GLP-1 RECEPTOR AGONIST AND METHOD OF MANUFACTURING THEREOF
KR102484756B1 (ko) * 2020-11-13 2023-01-06 한국생산기술연구원 용해성 증대 및 취급용이성을 갖는 파우더 배지의 과립화 방법
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

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DE362704C (de) * 1921-08-09 1922-11-02 Naamlooze Vennootschap Interna Vorrichtung zum Senken einer Last, insbesondere eines Rettungsbootes
US3174901A (en) 1963-01-31 1965-03-23 Jan Marcel Didier Aron Samuel Process for the oral treatment of diabetes
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Also Published As

Publication number Publication date
WO2000003742A3 (en) 2000-04-20
ID25784A (id) 2000-11-02
KR20040053177A (ko) 2004-06-23
AU2003261560A1 (en) 2005-05-26
TW200303208A (en) 2003-09-01
EP2269613A2 (en) 2011-01-05
DE69818444D1 (de) 2003-10-30
CA2303537C (en) 2005-12-06
RU2003126257A (ru) 2005-02-27
CA2303537A1 (en) 2000-01-27
UY25611A1 (es) 2000-08-21
CN1146427C (zh) 2004-04-21
EP1011684A2 (en) 2000-06-28
USRE38629E1 (en) 2004-10-19
AR065970A2 (es) 2009-07-15
EP0974356B1 (en) 2003-09-24
EP1435240A3 (en) 2009-08-12
JP2002520371A (ja) 2002-07-09
NZ503248A (en) 2002-09-27
US6303146B1 (en) 2001-10-16
MY129552A (en) 2007-04-30
CN1275082A (zh) 2000-11-29
JP2003292443A (ja) 2003-10-15
AU753604B2 (en) 2002-10-24
DZ2846A1 (fr) 2003-12-01
ES2206868T3 (es) 2004-05-16
TW555560B (en) 2003-10-01
EP1435240A2 (en) 2004-07-07
BR9906600A (pt) 2000-07-18
KR20010030603A (ko) 2001-04-16
AP2000001757A0 (en) 2000-03-31
TWI245632B (en) 2005-12-21
KR100478347B1 (ko) 2005-03-23
AR013052A1 (es) 2000-11-22
SI0974356T1 (en) 2003-12-31
CN1486698A (zh) 2004-04-07
MA24930A1 (fr) 2000-04-01
PT974356E (pt) 2004-02-27
RU2286788C2 (ru) 2006-11-10
ATE250418T1 (de) 2003-10-15
AU5417999A (en) 2000-02-07
ZA200001159B (en) 2001-05-31
WO2000003742A2 (en) 2000-01-27
AP1450A (en) 2005-07-25
EP2269613A3 (en) 2012-10-17
RU2226396C2 (ru) 2004-04-10
DE69818444T2 (de) 2004-05-06
EP0974356A1 (en) 2000-01-26
OA11400A (en) 2004-04-08

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